About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
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IP: Marta Vila Pueyo Collaborators: Laila Asskour, Patricia Pozo Rosich, Victor José Gallardo Lopez, Otilia Gliga Funding agency: Fundación Eugenio Rodríguez Pascual Funding: 24990 Reference: FERP-2023-MVP Duration: 17/01/2024 - 16/01/2026
IP: Patricia Pozo Rosich Collaborators: Otilia Gliga, Miriam Izquierdo Sans Funding agency: Instituto de Salud Carlos III Funding: 89900 Reference: FI23/00149 Duration: 01/01/2024 - 31/12/2027
IP: Patricia Pozo Rosich Collaborators: Edoardo Caronna, Miriam Izquierdo Sans Funding agency: Instituto de Salud Carlos III Funding: 180000 Reference: JR23/00065 Duration: 01/01/2024 - 31/12/2027
IP: Marta Vila Pueyo Collaborators: Laila Asskour, Victor José Gallardo Lopez Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 175000 Reference: PID2022-137287NA-I00 Duration: 01/09/2023 - 31/08/2026
PMID: 37038303 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 Jul;30(7):1937-1944. doi: 10.1111/ene.15816. Epub 2023 Apr 26. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Caronna, Edoardo; Gallardo, Victor J; Gine-Cipres, Eulalia; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al. DOI: 10.1111/ene.15816
PMID: 37516125 Journal: LANCET Year: 2023 Reference: Lancet. 2023 Jul 26:S0140-6736(23)01049-8. doi: 10.1016/S0140-6736(23)01049-8. Impact factor: Publication type: Paper in international publication Authors: Ailani, Jessica; Ashina, Messoud; Boinpally, Ramesh; De Abreu Ferreira, Rosa; Finnegan, Michelle; Goadsby, Peter J; Guo, Hua; Lipton, Richard B; Lu, Kaifeng; McCusker, Emily et al. DOI: 10.1016/S0140-6736(23)01049-8
PMID: 37665495 Journal: Current Neurology and Neuroscience Reports Year: 2023 Reference: Curr Neurol Neurosci Rep. 2023 Sep 4. doi: 10.1007/s11910-023-01296-w. Impact factor: Publication type: Review in international publication Authors: Caronna, Edoardo; Gomez-Dabo, Laura; Melgarejo-Martinez, Laura; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia et al. DOI: 10.1007/s11910-023-01296-w
PMID: 37691118 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2023 Reference: J Headache Pain. 2023 Sep 11;24(1):125. doi: 10.1186/s10194-023-01644-8. Impact factor: Publication type: Review in international publication Authors: Braniste, Diana; Burstein, Rami; Caronna, Edoardo; Chkhitunidze, Nino; Dapkute, Austeja; Gollion, Cedric; Gudadze, Tamari; Hoffmann, Jan; Labastida-Ramirez, Alejandro; Meksa, Liga et al. DOI: 10.1186/s10194-023-01644-8
PMID: 34600443 Journal: BRITISH JOURNAL OF PHARMACOLOGY Year: 2022 Reference: Br J Pharmacol. 2022 Feb;179(3):358-370. doi: 10.1111/bph.15699. Epub 2021 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Goadsby, Peter J; Holland, Philip R; Johnson, Kirk W; Loraine, Howard J; Murdock, Paul R; Page, Keith; Vila-Pueyo, Marta; Woodrooffe, Amanda J et al. DOI: 10.1111/bph.15699
PMID: 35354072 Journal: European Journal of Pharmacology Year: 2022 Reference: Eur J Pharmacol. 2022 May 5;922:174905. doi: 10.1016/j.ejphar.2022.174905. Epub 2022 Mar 27. Impact factor: Publication type: Paper in international publication Authors: Araya, Erika Ivanna; Baggio, Darciane Favero; Chichorro, Juliana Geremias; Koren, Laura de Oliveira; Schwarting, Rainer K W et al. DOI: 10.1016/j.ejphar.2022.174905
PMID: 35166156 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Jul;42(8):804-809. doi: 10.1177/03331024211068074. Epub 2022 Feb 15. Impact factor: 6.295 Publication type: Paper in international publication Authors: Pozo-Rosich, Patricia; de Lorenzo, Inigo; Garcia-Azorin, David; Layos-Romero, Almudena; Porta-Etessam, Jesus; Membrilla, Javier A; Caronna, Edoardo; Gonzalez-Martinez, Alicia; Mencia, Alvaro Sierra; Segura, Tomas et al. DOI: 10.1177/03331024211068074
PMID: 35716692 Journal: LANCET NEUROLOGY Year: 2022 Reference: Lancet Neurol. 2022 Jul;21(7):597-607. doi: 10.1016/S1474-4422(22)00185-5. Impact factor: 44.182 Publication type: Paper in international publication Authors: Lanteri-Minet, Michel; Pozo-Rosich, Patricia; Ettrup, Anders; Christoffersen, Cecilie Laurberg; Josiassen, Mette Krog; Phul, Ravinder; Sperling, Bjorn; Ashina, Messoud et al. DOI: 10.1016/S1474-4422(22)00185-5
PMID: 33832802 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Mar 19;36(8):611-7. doi: 10.1016/j.nrl.2021.03.003. Impact factor: Publication type: Paper in international publication Authors: Alpuente, A; Caronna, E; Gago-Veiga, A B; Irimia Sieira, P; Jose Gallardo, V; Lopez-Bravo, A; Lopez-Veloso, A C; Porta-Etessam, J; Pozo-Rosich, P; Sanchez-Mateo, N M et al. DOI: 10.1016/j.nrl.2021.03.003
PMID: 34903177 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 Dec 13;22(1):151. doi: 10.1186/s10194-021-01366-9. Impact factor: 7.277 Publication type: Paper in international publication Authors: Gallardo, Victor J, Alpuente, Alicia, Pozo-Rosich, Patricia, Torres-Ferrus, Marta, Caronna, Edoardo et al. DOI: 10.1186/s10194-021-01366-9
PMID: 34766205 Journal: Current Pain and Headache Reports Year: 2021 Reference: Curr Pain Headache Rep. 2021 Nov 11;25(11):73. doi: 10.1007/s11916-021-00987-8. Impact factor: 3.494 Publication type: Review in international publication Authors: Caronna, Edoardo, Pozo-Rosich, Patricia et al. DOI: 10.1007/s11916-021-00987-8
PMID: 34601726 Journal: HEADACHE Year: 2021 Reference: Headache. 2021 Oct;61(9):1403-1410. doi: 10.1111/head.14225. Epub 2021 Oct 3. Impact factor: 5.887 Publication type: Paper in international publication Authors: Gallardo, Victor J, Alpuente, Alicia, Cerda-Company, Xim, Torres-Ferrus, Marta, Sanchez Del Rio, Margarita, Lainez, Jose Miguel, Leira, Rogelio, Trochet, Jerome, Pozo-Rosich, Patricia et al. DOI: 10.1111/head.14225
PMID: 33146036 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Nov;40(13):1410-1421. doi: 10.1177/0333102420965157. Impact factor: 4.868 Publication type: Paper in international publication Authors: Caronna, Edoardo, Ballve, Alejandro, Llaurado, Arnau, Gallardo, Victor Jose, Maria Ariton, Diana, Lallana, Sofia, Maza, Samuel Lopez, Gadea, Marta Olive, Quibus, Laura, Restrepo, Juan Luis et al. DOI: 10.1177/0333102420965157
PMID: 32968102 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Sep 23;10(1):15527. doi: 10.1038/s41598-020-72220-2. Impact factor: 3.998 Publication type: Paper in international publication Authors: Marti-Marca, Angela, Deco, Gustavo, Cos, Ignasi et al. DOI: 10.1038/s41598-020-72220-2
PMID: 32664898 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2020 Reference: J Headache Pain. 2020 Jul 14;21(1):90. doi: 10.1186/s10194-020-01135-0. Impact factor: 4.797 Publication type: Review in international publication Authors: Caronna, Edoardo, Benemei, Silvia, Labastida-Ramirez, Alejandro, Abramova, Ekaterina, Brunelli, Nicoletta, Diana, Paola, Gapeshin, Roman, Hofacker, Maxi Dana, Pias, Enrique Martinez, Maestrini, Ilaria et al. DOI: 10.1186/s10194-020-01135-0
PMID: 32657062 Journal: Journal of Clinical Neurology Year: 2020 Reference: J Clin Neurol. 2020 Jul;16(3):416-422. doi: 10.3988/jcn.2020.16.3.416. Impact factor: 2.439 Publication type: Paper in international publication Authors: Fonseca, Elena, Macaya, Alfons, Pozo-Rosich, Patricia, Gallardo, Victor Jose, Torres-Ferrus, Marta et al. DOI: 10.3988/jcn.2020.16.3.416
PMID: 31513849 Journal: NEUROBIOLOGY OF LEARNING AND MEMORY Year: 2019 Reference: Neurobiol Learn Mem. 2019 Dec;166:107085. doi: 10.1016/j.nlm.2019.107085. Epub 2019 Sep 9. Impact factor: 3.01 Publication type: Paper in international publication Authors: Salmi, Juha, Vila-Ballo, Adria, Soveri, Anna, Rostan, Carles, Rodriguez-Fornells, Antoni, Lehtonen, Minna, Laine, Matti et al. DOI: 10.1016/j.nlm.2019.107085
PMID: 31220392 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2019 Reference: Eur J Neurol. 2019 Dec;26(12):1464-1470. doi: 10.1111/ene.14028. Epub 2019 Jul 18. Impact factor: 4.387 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Alvarez-Sabin, Jose, Pozo-Rosich, Patricia et al. DOI: 10.1111/ene.14028
PMID: 30950844 Journal: CURRENT OPINION IN NEUROLOGY Year: 2019 Reference: Curr Opin Neurol. 2019 Jun;32(3):395-404. doi: 10.1097/WCO.0000000000000689. Impact factor: 4.647 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Alpuente, Alicia, Pozo-Rosich, Patricia et al. DOI: 10.1097/WCO.0000000000000689
PMID: 30834194 Journal: Epilepsy & behavior case reports Year: 2019 Reference: Epilepsy Behav Case Rep. 2019 Feb 7;11:92-95. doi: 10.1016/j.ebcr.2019.01.008. eCollection 2019. Impact factor: 0 Publication type: Paper in international publication Authors: Santamarina, Estevo, Alpuente, Alicia, Maisterra, Olga, Sueiras, Maria, Sarria, Silvana, Guzman, Lorena, Abraira, Laura, Salas-Puig, Javier, Toledo, Manuel et al. DOI: 10.1016/j.ebcr.2019.01.008
PMID: 30386285 Journal: Frontiers in Neurology Year: 2018 Reference: Front Neurol. 2018 Oct 16;9:808. doi: 10.3389/fneur.2018.00808. eCollection 2018. Impact factor: 3.508 Publication type: Paper in international publication Authors: Caronna, Edoardo, Gallardo, Victor Jose, Hernandez-Beltran, Natalia, Torres-Ferrus, Marta, Pozo-Rosich, Patricia et al. DOI: 10.3389/fneur.2018.00808
PMID: 30384104 Journal: EPILEPSY & BEHAVIOR Year: 2018 Reference: Epilepsy Behav. 2018 Dec;89:8-14. doi: 10.1016/j.yebeh.2018.09.046. Epub 2018 Oct 26. Impact factor: 2.6 Publication type: Paper in international publication Authors: Santamarina, Estevo, Parejo, Beatriz, Abraira, Laura, Gutierrez-Viedma, Alvaro, Alpuente, Alicia, Abarrategui, Belen, Toledo, Manuel, Mazuela, Gonzalo, Salas-Puig, Xavier, Garcia-Morales, Irene et al. DOI: 10.1016/j.yebeh.2018.09.046
PMID: 30143565 Journal: NEUROLOGY Year: 2018 Reference: Neurology. 2018 Sep 25;91(13):622-624. doi: 10.1212/WNL.0000000000006251. Epub 2018 Aug 24. Impact factor: 8.055 Publication type: Paper in international publication Authors: Midaglia, Luciana, Gratacos, Margarida, Caronna, Edoardo, Raguer, Nuria, Sastre-Garriga, Jaume, Montalban, Xavier, Tintore, Mar et al. DOI: 10.1212/WNL.0000000000006251
PMID: 29339147 Journal: BIOLOGICAL PSYCHOLOGY Year: 2018 Reference: Biol Psychol. 2018 Feb;132:233-243. doi: 10.1016/j.biopsycho.2018.01.007. Epub 2018 Jan 12. Impact factor: 2.891 Publication type: Paper in international publication Authors: Vila-Ballo, Adria, Salmi, Juha, Soveri, Anna, Lehtonen, Minna, Laine, Matti, Rodriguez-Fornells, Antoni et al. DOI: 10.1016/j.biopsycho.2018.01.007
PhD student: Angela Barbara Marti Marca Director/s: Patricia Pozo Rosich, Adria Vila Ballo University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Victor José Gallardo Lopez Director/s: Patricia Pozo Rosich, José Alvarez Sabin University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Alicia Alpuente Ruiz Director/s: José Alvarez Sabin, Patricia Pozo Rosich University: Year: 2023
PhD student: Edoardo Caronna Director/s: Patricia Pozo Rosich, José Alvarez Sabin University: Year: 2022
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
