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Headache and Neurological Pain

Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.

Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.

Team

Laura Gómez Dabó

Laura Gómez Dabó

Predoctoral researcher
Headache and Neurological Pain
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Maria Teresa Mateu Peláez

Maria Teresa Mateu Peláez

Predoctoral researcher
Headache and Neurological Pain
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Muñoz Adelantado, Estefanía

Muñoz Adelantado, Estefanía

Research technician
Headache and Neurological Pain
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Rut Mas deles Valls Cierco

Rut Mas deles Valls Cierco

Research technician
Headache and Neurological Pain
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Edoardo Caronna

Edoardo Caronna

Predoctoral researcher
Headache and Neurological Pain
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Eulalia Gine Cipres

Eulalia Gine Cipres

Headache and Neurological Pain
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Laura Gómez Dabó

Laura Gómez Dabó

Predoctoral researcher
Headache and Neurological Pain
Read more
Maria Teresa Mateu Peláez

Maria Teresa Mateu Peláez

Predoctoral researcher
Headache and Neurological Pain
Read more
Muñoz Adelantado, Estefanía

Muñoz Adelantado, Estefanía

Research technician
Headache and Neurological Pain
Read more
Rut Mas deles Valls Cierco

Rut Mas deles Valls Cierco

Research technician
Headache and Neurological Pain
Read more
Edoardo Caronna

Edoardo Caronna

Predoctoral researcher
Headache and Neurological Pain
Read more
Eulalia Gine Cipres

Eulalia Gine Cipres

Headache and Neurological Pain
Read more

Projects

Role of microglia in preclinical models of migraine

IP: Marta Vila Pueyo
Collaborators: -
Funding agency: Fundació "La Caixa"
Funding: 305100
Reference: LCF/BQ/PI23/11970015
Duration: 31/12/2023 - 30/12/2026

(PREDIMIGRAINE) Medicina de precisión para prevenir la cronificación de la migraña a través de la predicción de las crisis de dolor y de la respuesta al tratamiento con anticuerpos anti-CGRP utilizando estrategias multi-ómicas.

IP: Patricia Pozo Rosich
Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna
Funding agency: Instituto de Salud Carlos III
Funding: 369930
Reference: PMP22/00189
Duration: 01/01/2023 - 31/12/2025

Cefalea i dolor neurològic

IP: Patricia Pozo Rosich
Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Marta Torres Ferrús, Vila Ballo, Adria, Victor José Gallardo Lopez, Nara Ikumi Montserrat, Marta Vila Pueyo, Edoardo Caronna
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00406
Duration: 01/01/2022 - 30/06/2025

BiOmarcadores Moleculares y clínicos de respuesta al tratamiento en los Ataques de Migraña (Estudio MAMBO).

IP: Marta Torres Ferrús
Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna, Laura Gómez Dabó
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/01530
Duration: 01/01/2023 - 31/12/2025

Publications

Epidemiology, burden and clinical spectrum of cluster headache: a global update.

PMID: 37728577
Journal: CEPHALALGIA
Year: 2023
Reference: Cephalalgia. 2023 Sep;43(9):3331024231201577. doi: 10.1177/03331024231201577.
Impact factor:
Publication type: Review in international publication
Authors: Choi, So Youn; Kim, Seung Ae; Lee, Mi Ji; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Youn, Michelle Sojung et al.
DOI: 10.1177/03331024231201577

The Green Surgical Block 4.0: Automation of the operating theatre's climate conditions through a real-time patient-flow solution.

PMID: 37786502
Journal: Future healthcare journal
Year: 2023
Reference: Future Healthc J. 2023 Mar;10(1):46-49. doi: 10.7861/fhj.2022-0142.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Anna Ochoa de Echaguen; Carbonell-Cobo, Marta; de Castro, Rodolfo; Hueto-Madrid, Juan Antonio; Paradell, Raquel Canovas; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Rovira-Simon, Jordi; Sales-I-Coll, Marc; Shaw, Genevieve et al.
DOI: 10.7861/fhj.2022-0142

Migraine worsening after COVID-19 and COVID-19 vaccination: Are we facing a nocebo effect?

PMID: 37791410
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2023
Reference: Eur J Neurol. 2023 Oct 4. doi: 10.1111/ene.16058.
Impact factor:
Publication type: Paper in international publication
Authors: Alpuente, Alicia; Alpuente, Alicia; Caronna, Edoardo; Elosua-Bayes, Iker; Gallardo, Victor J; Gallardo, Victor J; Melgarejo, Laura; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Rosell-Mirmi, Joana et al.
DOI: 10.1111/ene.16058

Impact of monthly headache days on migraine-related quality of life: Results from the Chronic Migraine Epidemiology and Outcomes (CaMEO) study.

PMID: 37795746
Journal: HEADACHE
Year: 2023
Reference: Headache. 2023 Oct 5. doi: 10.1111/head.14629.
Impact factor:
Publication type: Paper in international publication
Authors: Buse, Dawn C; Dabruzzo, Brett; Fanning, Kristina M; Lipton, Richard B; Orr, Serena L; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Reed, Michael L et al.
DOI: 10.1111/head.14629

Migraine-attributed burden, impact and disability, and migraine-impacted quality of life: Expert consensus on definitions from a Delphi process.

PMID: 35791285
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Jul 5:3331024221110102. doi: 10.1177/03331024221110102.
Impact factor: 6.295
Publication type: Paper in international publication
Authors: Steiner, Timothy J; Terwindt, Gisela M; Katsarava, Zaza; Pozo-Rosich, Patricia; Gantenbein, Andreas R; Roche, Sarah L; Dell'Agnello, Grazia; Tassorelli, Cristina et al.
DOI: 10.1177/03331024221110102

Avoidance behaviour modulates but does not condition phonophobia in migraine.

PMID: 35815637
Journal: CEPHALALGIA
Year: 2022
Reference: Cephalalgia. 2022 Jul 9:3331024221111772. doi: 10.1177/03331024221111772.
Impact factor: 6.295
Publication type: Paper in international publication
Authors: Pozo-Rosich, Patricia, Gallardo, Victor Jose, Caronna, Edoardo, Vila-Ballo, Adria, Marti-Marca, Angela, Cerda-Company, Xim, Ikumi, Nara et al.
DOI: 10.1177/03331024221111772

The influence of temporal unpredictability on the electrophysiological mechanisms of neural entrainment.

PMID: 35678104
Journal: PSYCHOPHYSIOLOGY
Year: 2022
Reference: Psychophysiology. 2022 Jun 9:e14108. doi: 10.1111/psyp.14108.
Impact factor: 4.016
Publication type: Paper in international publication
Authors: Pozo-Rosich, Patricia, Soto-Faraco, Salvador, Torralba Cuello, Mireia, Marti-Marca, Angela, Vila-Ballo, Adria et al.
DOI: 10.1111/psyp.14108

Twenty twenty ... two: Headache and COVID-19.

PMID: 35670131
Journal: HEADACHE
Year: 2022
Reference: Headache. 2022 Jun;62(6):648-649. doi: 10.1111/head.14330. Epub 2022 Jun 7.
Impact factor: 5.887
Publication type: Letter or abstract
Authors: Pozo-Rosich, Patricia, Caronna, Edoardo et al.
DOI: 10.1111/head.14330

Is There a Gender Difference in the Response to onabotulinumtoxinA in Chronic Migraine? Insights from a Real-Life European Multicenter Study on 2879 Patients.

PMID: 34564833
Journal: Pain and Therapy
Year: 2021
Reference: Pain Ther. 2021 Dec;10(2):1605-1618. doi: 10.1007/s40122-021-00328-y. Epub 2021 Sep 26.
Impact factor: 5.725
Publication type: Paper in international publication
Authors: Kamm, Katharina, Ruscheweyh, Ruth, Russo, Marco, Torelli, Paola, Filatova, Elena, Latysheva, Nina, Gryglas-Dworak, Anna, Straburzynski, Marcin, Butera, Calogera, Colombo, Bruno et al.
DOI: 10.1007/s40122-021-00328-y

Toward a better understanding of persistent headache after mild COVID-19: Three migraine-like yet distinct scenarios.

PMID: 34363619
Journal: HEADACHE
Year: 2021
Reference: Headache. 2021 Sep;61(8):1277-1280. doi: 10.1111/head.14197. Epub 2021 Aug 7.
Impact factor: 5.887
Publication type: Letter or abstract
Authors: Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Alpuente, Alicia, Caronna, Edoardo et al.
DOI: 10.1111/head.14197

Cortical metabolic and structural differences in patients with chronic migraine. An exploratory (18)FDG-PET and MRI study.

PMID: 34273945
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2021
Reference: J Headache Pain. 2021 Jul 17;22(1):75. doi: 10.1186/s10194-021-01289-5.
Impact factor: 7.277
Publication type: Paper in international publication
Authors: Torres-Ferrus, Marta, Pareto, Deborah, Gallardo, Victor J, Cuberas-Borros, Gemma, Alpuente, Alicia, Caronna, Edoardo, Vila-Ballo, Adria, Lorenzo-Bosquet, Carles, Castell-Conesa, Joan, Rovira, Alex et al.
DOI: 10.1186/s10194-021-01289-5

MAB-MIG: registry of the spanish neurological society of erenumab for migraine prevention.

PMID: 34273947
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2021
Reference: J Headache Pain. 2021 Jul 17;22(1):74. doi: 10.1186/s10194-021-01267-x.
Impact factor: 7.277
Publication type: Paper in international publication
Authors: Alberte-Woodward, Miguel, Jurado, Carmen, Oms, Teresa, Ezpeleta, David, de Teran, Javier Diaz, Morollon, Noemi, Latorre, German, Torres-Ferrus, Marta, Alpuente, Alicia, Lamas, Raquel et al.
DOI: 10.1186/s10194-021-01267-x

Influence of headache pain intensity and frequency on migraine-related disability in chronic migraine patients treated with OnabotulinumtoxinA.

PMID: 32652924
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2020
Reference: J Headache Pain. 2020 Jul 11;21(1):88. doi: 10.1186/s10194-020-01157-8.
Impact factor: 4.797
Publication type: Paper in international publication
Authors: Torres-Ferrus, Marta, Gallardo, Victor Jose, Alpuente, Alicia, Pozo-Rosich, Patricia et al.
DOI: 10.1186/s10194-020-01157-8

Long-term prognosis related to deep sedation in refractory status epilepticus.

PMID: 32614067
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2020
Reference: Acta Neurol Scand. 2020 Dec;142(6):555-562. doi: 10.1111/ane.13302. Epub 2020 Jul 29.
Impact factor: 2.684
Publication type: Paper in international publication
Authors: Caronna, Edoardo, Sanchez Corral, Anna, Santafe, Manel, Sueiras, Maria, Guzman, Lorena, Quintana, Manuel, Toledo-Argany, Manuel, Santamarina, Estevo, Gracia Gozalo, Rosa Maria, Vilaseca, Andreu et al.
DOI: 10.1111/ane.13302

Evaluation of the concomitant use of oral preventive treatments and OnabotulinumtoxinA in chronic migraine: the PREVENBOX study.

PMID: 32421912
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2020
Reference: Eur J Neurol. 2020 Oct;27(10):2102-2108. doi: 10.1111/ene.14331. Epub 2020 Jun 17.
Impact factor: 4.516
Publication type: Paper in international publication
Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Santos-Lasaosa, Sonia, Guerrero, Angel, Lainez, Jose Miguel, Viguera, Javier, Gago-Veiga, Ana, Irimia, Pablo, Del Rio, Margarita Sanchez et al.
DOI: 10.1111/ene.14331

From transformation to chronification of migraine: pathophysiological and clinical aspects.

PMID: 32349653
Journal: JOURNAL OF HEADACHE AND PAIN
Year: 2020
Reference: J Headache Pain. 2020 Apr 29;21(1):42. doi: 10.1186/s10194-020-01111-8.
Impact factor: 4.797
Publication type: Review in international publication
Authors: Lampl, C, van Hoogstraten, W S, Van den Abbeele, D, Torres-Ferrus, M, Ursitti, F, Alpuente-Ruiz, A, Brunello, F, Chiappino, D, de Vries, T, Di Marco, S et al.
DOI: 10.1186/s10194-020-01111-8

Headache, comorbidities and lifestyle in an adolescent population (The TEENs Study).

PMID: 29771141
Journal: CEPHALALGIA
Year: 2019
Reference: Cephalalgia. 2019 Jan;39(1):91-99. doi: 10.1177/0333102418777509. Epub 2018 May 17.
Impact factor: 4.438
Publication type: Paper in international publication
Authors: Torres-Ferrus, Marta, Vila-Sala, Carme, Quintana, Manuel, Ajanovic, Sara, Gallardo, Victor Jose, Gomez, Juan Bernardo, Alvarez-Sabin, Jose, Macaya, Alfons, Pozo-Rosich, Patricia et al.
DOI: 10.1177/0333102418777509

Blog

News

The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.

The results show that tobacco affects the expression of some genes related to the development of this type of headache.

Aquests guardons reconeixen els millors serveis i unitats de l’Estat, tant públics com privats, que busquen l’excel•lència en l’atenció que presten als seus pacients.

Job offers

Research Coordinator-Headache Clinical Unit.
Start date:
27/04/2023
End date:
31/05/2023
Document: Download
Biostatistician-Headache Clinical Unit.
Start date:
30/01/2023
End date:
13/02/2023
Document: Download
Neurologist-Headache Unit.
Start date:
19/12/2022
End date:
02/01/2023
Document: Download