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Infection and Immunity in pediatric patients

The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.

The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.

Publications

Antibiotic Prescribing in Children Hospitalized With COVID-19 and Multisystem Inflammatory Syndrome in Spain: Prevalence, Trends, and Associated Factors.

PMID: 35188190
Journal: Journal of the Pediatric Infectious Diseases Society
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 May 30;11(5):225-228. doi: 10.1093/jpids/piac003.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Alonso, David; Ballesteros, Alvaro; Calvo, Cristina; Caro-Teller, Jose Manuel; Cervantes Hernandez, Eloisa; Cobos-Carrascosa, Elena; Dominguez-Rodriguez, Sara; Epalza, Cristina; Gomez, Marisa Navarro; Gonzalez Montero, Raul et al.
DOI: 10.1093/jpids/piac003

Multicenter Prospective Study of Biomarkers for Diagnosis of Invasive Candidiasis in Children and Adolescents.

PMID: 35134165
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2022
Reference: Clin Infect Dis. 2022 Aug 25;75(2):248-259. doi: 10.1093/cid/ciab928.
Impact factor:
Publication type: Paper in international publication
Authors: Allen, John; Berman, David; Boge, Craig L K; Chang, Yeh-Chung; Chin-Quee, Dawn; Danziger-Isakov, Lara; Doby Knackstedt, Elizabeth; Fisher, Brian T; Gonzalez, Blanca E; Green, Michael et al.
DOI: 10.1093/cid/ciab928

Antimicrobial defined daily dose in neonatal population.

PMID: 35120651
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2022
Reference: Enferm Infecc Microbiol Clin. 2022 Feb;40(2):59-65. doi: 10.1016/j.eimce.2021.05.012.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez Del Vayo-Benito, Concepcion; Catillo-Salinas, Felix; Comunas, Juanjo; Dolz, Elisenda; Fernandez-Llamazares, Cecilia M; Fernandez-Polo, Aurora; Gallego-Fernandez, Carmen; Gazquez-Perez, Rocio; Gil-Navarro, Maria-Victoria; Gomez-Trevecedo Calvo, Maria-Teresa et al.
DOI: 10.1016/j.eimc.2021.05.007

Antimicrobial stewardship programs in pediatrics: A growing reality in our country.

PMID: 35120649
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2022
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2022 Feb;40(2):51-52. doi: 10.1016/j.eimce.2021.12.007.
Impact factor:
Publication type: Editorail in international publication
Authors: Fernandez-Polo, Aurora; Soler-Palacin, Pere et al.
DOI: 10.1016/j.eimce.2021.12.007

Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.

PMID: 33484697
Journal: JOURNAL OF PEDIATRICS
Year: 2021
Reference: J Pediatr. 2021 May;232:287-289.e4. doi: 10.1016/j.jpeds.2021.01.027. Epub 2021 Jan 21.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Alonso, David; Alcala, Pedro; Alfayate, Santiago; Alonso, J A; Alonso, M; Alonso, Maruchi; Alvaredo, Teresa; Amich, Ines; Ara, Fatima; Astigarraga, Itziar et al.
DOI: 10.1016/j.jpeds.2021.01.027

Mortality in Perinatally HIV-infected Adolescents After Transition to Adult Care in Spain.

PMID: 33264211
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2021
Reference: Pediatr Infect Dis J. 2021 Apr 1;40(4):347-350. doi: 10.1097/INF.0000000000003009.
Impact factor:
Publication type: Paper in international publication
Authors: Albendin Iglesias, Helena; Berzosa Sanchez, Arantxa; Bisbal, Otilia; Carrasco, Itziar; Cervero, Miguel; Couceiro, Jose Antonio; Fortuny Guash, Claudia; Frick, M Antoinette; Jimenez De Ory, Santiago; Mellado, M feminine Jose et al.
DOI: 10.1097/INF.0000000000003009

Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions.

PMID: 32229130
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin. 2021 Mar;39(3):134-138. doi: 10.1016/j.eimc.2020.02.015. Epub 2020 Mar 27.
Impact factor:
Publication type: Paper in national publication
Authors: Alonso Garcia, Laura; Barnes-Mayolas, Meritxell; Castellnou Asens, Ivette; Castilla Fernandez, Yolanda; Estrella Barcelo, Maria; Fernandez Polo, Aurora; Fernandez-Polo, Aurora; Lopez Fernandez, Sergio; Melendo Perez, Susana; Melendo, Susana et al.
DOI: 10.1016/j.eimc.2020.02.015

Compassionate use of remdesivir in children with COVID-19.

PMID: 33200304
Journal: EUROPEAN JOURNAL OF PEDIATRICS
Year: 2021
Reference: Eur J Pediatr. 2021 Apr;180(4):1317-1322. doi: 10.1007/s00431-020-03876-1. Epub 2020 Nov 16.
Impact factor:
Publication type: Paper in international publication
Authors: Ara, Maria Fatima; Cabanas, Fernando; Calvo, Cristina; Gonzalez Del Valle, Luis; Melendo, Susana; Mendez-Echevarria, Ana; Morales-Martinez, Antonio; Perez-Martinez, Antonio; Remesal, Agustin; Ruiz de Valbuena, Marta et al.
DOI: 10.1007/s00431-020-03876-1

Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies.

PMID: 33161963
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2020
Reference: J Allergy Clin Immunol Pract. 2020 Nov - Dec;8(10):3342-3347. doi: 10.1016/j.jaip.2020.05.008.
Impact factor: 7.574
Publication type: Review in international publication
Authors: Cordero, Elisa, Goycochea-Valdivia, Walter, Mendez-Echevarria, Ana, Allende, Luis M, Alsina, Laia, Bravo Garcia-Morato, Maria, Neth, Olaf, Rodriguez-Gallego, Carlos, Santos-Perez, Juan Luis, Rodriguez Pena, Rebeca et al.
DOI: 10.1016/j.jaip.2020.05.008

Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies.

PMID: 33161954
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin. 2020 Nov;38(9):438-443. doi: 10.1016/j.eimc.2020.07.001.
Impact factor: 1.654
Publication type: Review in national publication
Authors: Aguilera Cros, Clara, Cordero, Elisa, Goycochea-Valdivia, Walter, Mendez-Echevarria, Ana, Allende, Luis M, Alsina, Laia, Bravo Garcia-Morato, Maria, Gil-Herrera, Juana, Gudiol, Carlota, Len-Abad, Oscar et al.
DOI: 10.1016/j.eimc.2020.07.001

Auto-antibodies against type I IFNs in patients with life-threatening COVID-19.

PMID: 32972996
Journal: SCIENCE
Year: 2020
Reference: Science. 2020 Oct 23;370(6515). pii: science.abd4585. doi: 10.1126/science.abd4585. Epub 2020 Sep 24.
Impact factor: 41.845
Publication type: Paper in international publication
Authors: Manry, Jeremy, Shaw, Elana, Haljasmagi, Liis, Peterson, Part, Lorenzo, Lazaro, Bizien, Lucy, Trouillet-Assant, Sophie, Dobbs, Kerry, de Jesus, Adriana Almeida, Belot, Alexandre et al.
DOI: 10.1126/science.abd4585

Adverse Events Associated With New Injectable-Free Multidrug-Resistant Tuberculosis Drug Regimens.

PMID: 32800388
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2020
Reference: Arch Bronconeumol. 2020 Dec;56(12):823-825. doi: 10.1016/j.arbres.2020.07.006. Epub 2020 Aug 13.
Impact factor: 4.957
Publication type: Letter whit IF
Authors: Mendoza-Palomar, Natalia, Soler-Palacin, Pere, Schaaf, H Simon, Soriano-Arandes, Antoni, Melendo-Perez, Susana, Martin-Nalda, Andrea, Lopez-Seguer, Laura, Carreras-Abad, Clara, Espiau, Maria, Martin-Begue, Nieves et al.
DOI: 10.1016/j.arbres.2020.07.006

Blog

News

The study seeks to better understand blood disorders in children and young people, analyzing the role of immunological alterations to improve diagnosis and treatment.

Members of the RBDCOV project, which involves VHIR, gathered at the Palau Macaya to review progress and achievements made during the final phase of the project.

During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.