Skip to main content

Infection and Immunity in pediatric patients

The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.

The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.

Publications

Formation of an invasion-permissive matrix requires TGFbeta/SNAIL1-regulated alternative splicing of fibronectin.

PMID: 37964360
Journal: BREAST CANCER RESEARCH
Year: 2023
Reference: Breast Cancer Res. 2023 Nov 14;25(1):143. doi: 10.1186/s13058-023-01736-y.
Impact factor:
Publication type: Paper in international publication
Authors: Baulida, Josep; Benitez-Carbante, Maria Isabel; Benitez-Carbante, Maria Isabel; Diaz de Heredia, Cristina; Eyras, Eduardo; Fernandez Ledesma, Berta; Fernandez Ledesma, Berta; Fernandez-Polo, Aurora; Franco-Valls, Hector; Garcia de Herreros, Antonio et al.
DOI: 10.1186/s13058-023-01736-y

Renal Function Impairment in Children With Congenital Cytomegalovirus Infection: A Cross-sectional Study.

PMID: 38063508
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2023
Reference: Pediatr Infect Dis J. 2023 Dec 6. doi: 10.1097/INF.0000000000004176.
Impact factor:
Publication type: Paper in international publication
Authors: Alarcon, Ana; Alonso-Ojembarrena, Almudena; Baquero-Artigao, Fernando; Benavides, Marta; Blazquez-Gamero, Daniel; Bringue, Xavier; Castells-Vilella, Laura; Del Valle, Rut; Esteva, Cristina; Fortuny, Claudia et al.
DOI: 10.1097/INF.0000000000004176

Reply to "MOG Antibody-Positive Patients Meeting the 2017 McDonald Criteria for MS: Challenges in Diagnosis and Treatment Decisions".

PMID: 38081749
Journal: ANNALS OF NEUROLOGY
Year: 2023
Reference: Ann Neurol. 2023 Dec 11. doi: 10.1002/ana.26856.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Alvarez-Fernandez, Antonio; Canete-Ramirez, Carme; Cobo-Calvo, Alvaro; Espejo, Carmen; Fernandez-Polo, Aurora; Gartner, Silvia; Jimenez-Lozano, Ines; Luna-Paredes, Carmen; Monte-Boquet, Emilio; Roch-Santed, Maria et al.
DOI: 10.1002/ana.26856

Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain.

PMID: 38145114
Journal:
Year: 2023
Reference: J Health Econ Outcomes Res. 2023 Dec 20;10(2):141-149. doi: 10.36469/001c.85088. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Jordi; Bittermann, Violetta; Bou, Rosa; Calvo Penades, Immaculada; Calzada Hernandez, Joan; Carriqui Arenas, Sonia; de Alarcon, Aristides; de Lossada, Alfonso; Estepa Guillen, Carolina; Fernandez-Polo, Aurora et al.
DOI: 10.36469/001c.85088

Reply to Darcis, et al.

PMID: 34146094
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2022
Reference: Clin Infect Dis. 2022 Mar 1;74(4):747-749. doi: 10.1093/cid/ciab572.
Impact factor:
Publication type: Letter or abstract
Authors: Gatell, Anna; Perramon, Aida; Prats, Clara; Serrano, Pepe; Soler-Palacin, Pere; Soriano-Arandes, Antoni et al.
DOI: 10.1093/cid/ciab572

MDR Tuberculosis Treatment.

PMID: 35208510
Journal: Medicina-Lithuania
Year: 2022
Reference: Medicina (Kaunas). 2022 Jan 26;58(2). pii: medicina58020188. doi: 10.3390/medicina58020188.
Impact factor:
Publication type: Review in international publication
Authors: Aznar, Maria Luisa; Espiau, Maria; Espinosa-Pereiro, Juan; Sanchez-Montalva, Adrian et al.
DOI: 10.3390/medicina58020188

QTc interval prolongation in patients infected with SARS-CoV-2 and treated with antiviral drugs.

PMID: 35193834
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Mar;96(3):213-220. doi: 10.1016/j.anpede.2021.04.006. Epub 2022 Feb 19.
Impact factor:
Publication type: Paper in international publication
Authors: Dolader, Paola; Esmel-Vilomara, Roger; Gran, Ferran; Roses-Noguer, Ferran; Sabate-Rotes, Anna; Soriano-Arandes, Antoni et al.
DOI: 10.1016/j.anpedi.2021.04.009

Respiratory Syncytial Virus Infections in Young Children Presenting to Primary Care in Catalonia During the COVID-19 Pandemic.

PMID: 34922377
Journal: Journal of the Pediatric Infectious Diseases Society
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 Feb 23;11(2):69-72. doi: 10.1093/jpids/piab121.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Andres; Coma, Ermengol; Fabregas, Mireia; Fina, Francesc; Medina, Manuel; Mendez-Boo, Leonardo; Mora, Nuria; Vila, Jorgina et al.
DOI: 10.1093/jpids/piab121

Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy: a position paper.

PMID: 32979154
Journal: INFECTION
Year: 2021
Reference: Infection. 2021 Apr;49(2):215-231. doi: 10.1007/s15010-020-01521-5. Epub 2020 Sep 26.
Impact factor:
Publication type: Review in international publication
Authors: Aguilar-Guisado, Manuela; Alsina-Manrique, Laia; Barba, Pere; Diaz de Heredia, Cristina; Fortuny-Guasch, Claudia; Garcia-Cadenas, Irene; Garcia-Vidal, Carolina; Gonzalez-Vicent, Marta; Hernani, Rafael; Iacoboni, Gloria et al.
DOI: 10.1007/s15010-020-01521-5

A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?

PMID: 33730099
Journal: PLoS Neglected Tropical Diseases
Year: 2021
Reference: PLoS Negl Trop Dis. 2021 Mar 17;15(3):e0009144. doi: 10.1371/journal.pntd.0009144. eCollection 2021 Mar.
Impact factor:
Publication type: Review in international publication
Authors: Boralevi, Franck; Brenier-Pinchart, Marie-Pierre; Chaccour, Carlos J; Coulibaly, Jean T; Dard, Celine; Del Giudice, Pascal; Engelman, Daniel; Failoc-Rojas, Virgilio E; Faisant, Anne; Guerin, Philippe J et al.
DOI: 10.1371/journal.pntd.0009144

Infectious complications of non-surgical biliary tract manipulation in paediatric patients. Role of antibiotic prophylaxis.

PMID: 33715879
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2021 Mar 11. pii: S0213-005X(21)00045-8. doi: 10.1016/j.eimc.2021.01.019.
Impact factor:
Publication type: Paper in national publication
Authors: Juamperez-Gomi, Javier; Lung, Mayli; Melendo, Susana; Mendoza-Palomar, Natalia; Mercadal-Hally, Maria; Perez, Maria Mercedes; Quintero, Jesus; Soler-Palacin, Pere; Soria-Navarro, Beatriz et al.
DOI: 10.1016/j.eimc.2021.01.019

Household SARS-CoV-2 transmission and children: a network prospective study.

PMID: 33709135
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2021
Reference: Clin Infect Dis. 2021 Sep 15;73(6):e1261-e1269. doi: 10.1093/cid/ciab228.
Impact factor:
Publication type: Paper in international publication
Authors: Aceiton, Jordi; Ago, Cintia; Anton, Andres; Aulet, Lidia; Azemar, Joan; Bayona, Imma; Berbel, Evelyn; Biosca, Mireia; Bordas, Anna; Braviz, Lorena et al.
DOI: 10.1093/cid/ciab228

[Evaluation of the impact of the Spanish consensus document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED)].

PMID: 31980415
Journal: ANALES DE PEDIATRIA
Year: 2020
Reference: An Pediatr (Barc). 2020 Nov;93(5):289-296. doi: 10.1016/j.anpedi.2019.11.008. Epub 2020 Jan 21.
Impact factor:
Publication type: Paper in national publication
Authors: Acevedo, Adriana Vidal; Alonso, Matilde Bustillo; Anton, Maria Penin; Aristegui-Fernandez, Javier; Arranz, Leonor; Barnes, Maria Rios; Barreiro, Natalia Cerdeira; Barrero, Pedro Terol; Calvo Rey, Cristina; Campana, M Mercedes Bueno et al.
DOI: 10.1016/j.anpedi.2019.11.008

Longitudinal Evolution Of Vertically HIV/HCV Coinfected Vs HCV Monoinfected Children.

PMID: 31515866
Journal: JOURNAL OF VIRAL HEPATITIS
Year: 2020
Reference: J Viral Hepat. 2020 Jan;27(1):61-67. doi: 10.1111/jvh.13206. Epub 2019 Oct 30.
Impact factor:
Publication type: Paper in international publication
Authors: Diaz, M C; Dominguez-Rodriguez, S; Falcon, D; Fernandez McPhee, C; Fortuny, C; Gavilan, C; Guerrero, C; Hierro, L; Jara, P; Mellado, M J et al.
DOI: 10.1111/jvh.13206

Tocilizumab in a child with acute lymphoblastic leukaemia and COVID-19-related cytokine release syndrome.

PMID: 32837964
Journal: Anales de pediatria
Year: 2020
Reference: An Pediatr (Engl Ed). 2020 Aug;93(2):132-133. doi: 10.1016/j.anpede.2020.05.002. Epub 2020 Jul 1.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Diaz de Heredia, Cristina; Moreno, Lucas; Riviere, Jacques G; Soler Palacin, Pere; Velasco Puyo, Pablo et al.
DOI: 10.1016/j.anpede.2020.05.002

Prevalence of asymptomatic SARS-CoV-2 infection in children undergoing hospital screening.

PMID: 33160709
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2020 Oct 13;39(8):415-6. doi: 10.1016/j.eimc.2020.10.004.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Anton, Andres; Borras-Bermejo, Blanca; Soler-Palacin, Pere; Soriano-Arandes, Antoni et al.
DOI: 10.1016/j.eimc.2020.10.004

Blog

News

The study seeks to better understand blood disorders in children and young people, analyzing the role of immunological alterations to improve diagnosis and treatment.

Members of the RBDCOV project, which involves VHIR, gathered at the Palau Macaya to review progress and achievements made during the final phase of the project.

During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.