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Infectious Diseases

The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.

The group's lines of research are mainly focused on four areas:

Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.

Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).

Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.

Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.

Publications

Epidemiological and clinical profile of adult patients with diarrhoea after international travel attended in an International Health referral center.

PMID: 34839009
Journal: Travel Medicine and Infectious Disease
Year: 2022
Reference: Travel Med Infect Dis. 2022 Jan-Feb;45:102216. doi: 10.1016/j.tmaid.2021.102216. Epub 2021 Nov 25.
Impact factor: 6.211
Publication type: Paper in international publication
Authors: Salvador, Fernando, Oliveira, Ines, Goterris, Lidia, Trevino, Begona, Sanchez-Montalva, Adrian, Serre-Delcor, Nuria, Sulleiro, Elena, Rodriguez, Virginia, Aznar, Maria Luisa, Bosch-Nicolau, Pau et al.
DOI: 10.1016/j.tmaid.2021.102216

Time-Dependent COVID-19 Mortality in Patients With Cancer: An Updated Analysis of the OnCovid Registry.

PMID: 34817562
Journal: JAMA Oncology
Year: 2022
Reference: JAMA Oncol. 2022 Jan 1;8(1):114-122. doi: 10.1001/jamaoncol.2021.6199.
Impact factor: 31.777
Publication type: Paper in international publication
Authors: Guida, Annalisa, Pinato, David J, Patel, Meera, Scotti, Lorenza, Colomba, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto et al.
DOI: 10.1001/jamaoncol.2021.6199

Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019.

PMID: 35037379
Journal: HIV MEDICINE
Year: 2022
Reference: HIV Med. 2022 Aug;23(7):705-716. doi: 10.1111/hiv.13229. Epub 2022 Jan 17.
Impact factor: 3.18
Publication type: Paper in international publication
Authors: Jarrin, I, Fanciulli, Chiara, Berenguer, Juan, Busca, Carmen, Vivancos, Maria J, Tellez, Maria J, Dominguez, Lourdes, Domingo, Pere, Navarro, Jordi, Santos, Jesus et al.
DOI: 10.1111/hiv.13229

Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial.

PMID: 35024838
Journal: JAMA Network Open
Year: 2022
Reference: JAMA Netw Open. 2022 Jan 4;5(1):e2137277. doi: 10.1001/jamanetworkopen.2021.37277.
Impact factor: 8.485
Publication type: Paper in international publication
Authors: Almirante, Benito, Natera-Kindelan, Clara, Sorli, Luisa, Borrell, Nuria, Giner-Oncina, Livia, Amador-Prous, Concha, Shaw, Evelyn, Jover-Saenz, Alfredo, Molina, Jose, Martinez-Alvarez, Rosa M et al.
DOI: 10.1001/jamanetworkopen.2021.37277

Early Stepdown From Echinocandin to Fluconazole Treatment in Candidemia: A Post Hoc Analysis of Three Cohort Studies.

PMID: 34104670
Journal: Open Forum Infectious Diseases
Year: 2021
Reference: Open Forum Infect Dis. 2021 May 16;8(6):ofab250. doi: 10.1093/ofid/ofab250. eCollection 2021 Jun.
Impact factor: 3.835
Publication type: Paper in international publication
Authors: Merino, P, Machado, M, Guinea, J, Garcia-Rodriguez, J, Garnacho-Montero, J, Cardozo, C, Peman, J, Montejo, M, Fortun, J, Almirante, B et al.
DOI: 10.1093/ofid/ofab250

The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19.

PMID: 34104210
Journal: Therapeutic Advances in Gastroenterology
Year: 2021
Reference: Therap Adv Gastroenterol. 2021 May 30;14:17562848211016567. doi: 10.1177/17562848211016567. eCollection 2021.
Impact factor: 4.409
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel, Villagrasa, Ares, Simon-Talero, Macarena, Riveiro-Barciela, Mar, Ventura-Cots, Meritxell, Aguilera-Castro, Lara, Alvarez-Lopez, Patricia, Nordahl, Emilie A, Rivera-Esteban, Jesus M, Romero, Alba et al.
DOI: 10.1177/17562848211016567

Intra-Discrete Typing Unit TcV Genetic Variability of Trypanosoma cruzi in Chronic Chagas' Disease Bolivian Immigrant Patients in Barcelona, Spain.

PMID: 34095255
Journal: Frontiers in Cardiovascular Medicine
Year: 2021
Reference: Front Cardiovasc Med. 2021 May 20;8:665624. doi: 10.3389/fcvm.2021.665624. eCollection 2021.
Impact factor: 6.05
Publication type: Paper in international publication
Authors: de Oliveira, Maykon Tavares, Sulleiro, Elena, da Silva, Maria Claudia, Silgado, Aroa, de Lana, Marta, da Silva, Joao Santana, Molina, Israel, Marin-Neto, J Antonio et al.
DOI: 10.3389/fcvm.2021.665624

Risk of SARS-CoV-2 Infection in Previously Infected and Non-Infected Cohorts of Health Workers at High Risk of Exposure.

PMID: 34064314
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 May 4;10(9). pii: jcm10091968. doi: 10.3390/jcm10091968.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Sanchez-Montalva, Adrian, Fernandez-Naval, Candela, Anton, Andres, Dura, Xavier, Vimes, Alba, Silgado, Aroa, Velasquez-Orozco, Fernando, Espinosa-Pereiro, Juan, Salvador, Fernando, Pumarola, Tomas et al.
DOI: 10.3390/jcm10091968

Nonepidemic Kaposi sarcoma in a young man.

PMID: 32312182
Journal: INTERNATIONAL JOURNAL OF STD & AIDS
Year: 2020
Reference: Int J STD AIDS. 2020 May;31(6):600-602. doi: 10.1177/0956462420916291. Epub 2020 Apr 20.
Impact factor: 1.406
Publication type: Paper in international publication
Authors: Cabezas-Calderon, Victor, Vall-Mayans, Marti et al.
DOI: 10.1177/0956462420916291

Efficacy and safety assessment of different dosage of benznidazol for the treatment of Chagas disease in chronic phase in adults (MULTIBENZ study): study protocol for a multicenter randomized Phase II non-inferiority clinical trial.

PMID: 32293523
Journal: Trials
Year: 2020
Reference: Trials. 2020 Apr 15;21(1):328. doi: 10.1186/s13063-020-4226-2.
Impact factor: 1.883
Publication type: Paper in international publication
Authors: Molina-Morant, D, Fernandez, M L, Bosch-Nicolau, P, Sulleiro, E, Bangher, M, Salvador, F, Sanchez-Montalva, A, Ribeiro, A L P, de Paula, A M B, Eloi, S et al.
DOI: 10.1186/s13063-020-4226-2

Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Network for Research in Infectious Diseases (REIPI) and the Spanish Society of Haematology and Haemotherapy (SEHH) on the management of febrile neutropenia in patients with hematological malignancies.

PMID: 30926172
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2020
Reference: Enferm Infecc Microbiol Clin. 2020 Apr;38(4):174-181. doi: 10.1016/j.eimc.2019.01.013. Epub 2019 Mar 27.
Impact factor: 1.654
Publication type: Paper in national publication
Authors: Gudiol, Carlota, Aguilar-Guisado, Manuela, Azanza, Jose Ramon, Candel, Francisco Javier, Canton, Rafael, Carratala, Jordi, Garcia-Vidal, Carolina, Jarque, Isidro, Lizasoain, Manuel, Gil-Bermejo, Jose Molina et al.
DOI: 10.1016/j.eimc.2019.01.013

Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts.

PMID: 32216822
Journal: CRITICAL CARE
Year: 2020
Reference: Crit Care. 2020 Mar 26;24(1):117. doi: 10.1186/s13054-020-2793-y.
Impact factor: 6.407
Publication type: Paper in international publication
Authors: Valerio, Maricela, Sartor, Assunta, Bouza, Emilio, Munoz, Patricia, Garcia-Vidal, Carolina, Carratala, Jordi, Aguado, Jose Maria, Meroi, Marco, Cardozo, Celia, Cuervo, Guillermo et al.
DOI: 10.1186/s13054-020-2793-y

Extended-pulsed fidaxomicin versus vancomycin in patients 60 years and older with Clostridium difficile infection: cost-effectiveness analysis in Spain.

PMID: 30989419
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2019
Reference: Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1105-1111. doi: 10.1007/s10096-019-03503-4. Epub 2019 Apr 13.
Impact factor: 2.591
Publication type: Paper in international publication
Authors: Rubio-Terres, Carlos, Aguado, Jose Maria, Almirante, Benito, Cobo, Javier, Grau, Santiago, Salavert, Miguel, Gonzalez Antona Sanchez, Elena, Lopez Gutierrez, Cristina, Rubio-Rodriguez, Dario et al.
DOI: 10.1007/s10096-019-03503-4

Novel tp0548 sequence-type of Treponema pallidum identified in Barcelona, Spain.

PMID: 30461599
Journal: SEXUALLY TRANSMITTED DISEASES
Year: 2019
Reference: Sex Transm Dis. 2019 May;46(5):e50-e52. doi: 10.1097/OLQ.0000000000000947.
Impact factor: 2.27
Publication type: Paper in international publication
Authors: Arando, Maider, Espasa, Mateu, Anton, Andres, Gimferrer, Laura, Pinana, Maria, Fernandez-Huerta, Miguel, Gonzalez-Lopez, Juan Jose, Serra-Pladevall, Judit, Pumarola, Tomas, Vall-Mayans, Marti et al.
DOI: 10.1097/OLQ.0000000000000947

Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study.

PMID: 30449728
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2019
Reference: Int J Infect Dis. 2019 Jan;78:34-38. doi: 10.1016/j.ijid.2018.10.005. Epub 2018 Oct 25.
Impact factor: 3.538
Publication type: Paper in international publication
Authors: Macias, Antonio, Sanchez-Montalva, Adrian, Salvador, Fernando, Villar, Ana, Tortola, Teresa, Saborit, Nuria, Molina, Israel et al.
DOI: 10.1016/j.ijid.2018.10.005

Plasmodium malariae in a Spanish traveller returning from Colombia.

PMID: 30924870
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2019
Reference: J Travel Med. 2019 Jun 1;26(4). pii: 5423127. doi: 10.1093/jtm/taz022.
Impact factor: 4.155
Publication type: Paper in international publication
Authors: Oliveira, I, Aznar, M L, Zarzuela, F, Sulleiro, E, Trevino, B, Serre, N, Pou, D, Salvador, F, Sanchez-Montalva, A, Bosch-Nicolau, P et al.
DOI: 10.1093/jtm/taz022

Cost-effectiveness analysis of combination antifungal therapy with voriconazole and anidulafungin versus voriconazole monotherapy for primary treatment of invasive aspergillosis in Spain.

PMID: 28115858
Journal: ClinicoEconomics and outcomes research : CEOR
Year: 2017
Reference: Clinicoecon Outcomes Res. 2016 Dec 30;9:39-47. doi: 10.2147/CEOR.S122177. eCollection 2017.
Impact factor: 0
Publication type: Paper in international publication
Authors: Ruiz, Isabel, Grau, Santiago, Azanza, Jose Ramon, Maertens, Johan, Heinz, Werner J, Barrueta, Jon Andoni, Peral, Carmen, Mesa, Francisco Jesus, Barrado, Miguel, Charbonneau, Claudie et al.
DOI: 10.2147/CEOR.S122177

Pharmacokinetic of benznidazole in healthy volunteers: Implications in future clinical trials.

PMID: 28167552
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2017
Reference: Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: AAC.01912-16. doi: 10.1128/AAC.01912-16. Print 2017 Apr.
Impact factor: 4.302
Publication type: Paper in international publication
Authors: Pedraz, J L, Pinto, L, Esquisabel, A, Perin, L, Molina, I, Salvador, F, Sanchez-Montalva, A, Artaza, M A, Moreno, R et al.
DOI: 10.1128/AAC.01912-16

PHARMACOKINETIC AND TISSUE DISTRIBUTION OF BENZNIDAZOLE AFTER ORAL ADMINISTRATION IN MICE.

PMID: 28167558
Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Year: 2017
Reference: Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: AAC.02410-16. doi: 10.1128/AAC.02410-16. Print 2017 Apr.
Impact factor: 4.302
Publication type: Paper in international publication
Authors: Perin, Luisa, Moreira da Silva, Rodrigo, da Silva Fonseca, Katia, Mirelle de Oliveira Cardoso, Jamille, Mathias, Fernando Augusto Siqueira, Reis, Levi Eduardo Soares, Molina, Israel, Correa-Oliveira, Rodrigo, de Abreu Vieira, Paula Melo, Carneiro, Claudia Martins et al.
DOI: 10.1128/AAC.02410-16

Impact of fluconazole susceptibility on the outcome of patients with candidemia: data from a population-based surveillance.

PMID: 28143788
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2017
Reference: Clin Microbiol Infect. 2017 Sep;23(9):672.e1-672.e11. doi: 10.1016/j.cmi.2017.01.014. Epub 2017 Jan 29.
Impact factor: 5.292
Publication type: Paper in international publication
Authors: Aguado, Jose Maria, Cuenca-Estrella, Manuel, Puig-Asensio, Mireia, Fernandez-Ruiz, Mario, Guinea, Jesus, Lora-Pablos, David, Zaragoza, Oscar, Almirante, Benito et al.
DOI: 10.1016/j.cmi.2017.01.014

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

Vall d'Hebron has coordinated this initiative that has carried out numerous training and community awareness activities aimed at empowering young people in sexual and reproductive health issues.