About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
IP: Rafael Esteban Mur Collaborators: Joan Genescà Ferrer Funding agency: Instituto de Salud Carlos III Funding: 30000 Reference: INT15/00040 Duration: 01/01/2016 - 31/12/2016
IP: - Collaborators: - Funding agency: Fundació Institut de Recerca HUVH Funding: 46800 Reference: PRED-VHIR-2015-21 Duration: 01/05/2016 - 30/04/2019
IP: Joan Genescà Ferrer Collaborators: - Funding agency: Fundació Institut de Recerca HUVH Funding: 46800 Reference: PRED-VHIR-2015-06 Duration: 09/02/2016 - 08/02/2018
IP: Rafael Esteban Mur Collaborators: Joan Genescà Ferrer Funding agency: Instituto de Salud Carlos III Funding: 18000 Reference: INT16/00109 Duration: 31/01/2017 - 31/12/2017
PMID: 38028633 Journal: Journal of intensive medicine Year: 2023 Reference: J Intensive Med. 2023 Jun 14;3(4):352-364. doi: 10.1016/j.jointm.2023.04.004. eCollection 2023 Oct 31. Impact factor: Publication type: Paper in international publication Authors: Amasi-Hartoonian, Nare; Ammour, Nadir; Begum, Amina; Blot, Stijn; Brown, Mollie; Couvert, Camille; Didden, Eva-Maria; Ege, Duygu; Genesca Ferrer, Joan; Griffon, Nicolas et al. DOI: 10.1016/j.jointm.2023.04.004
PMID: 38047909 Journal: HEPATOLOGY Year: 2023 Reference: Hepatology. 2023 Dec 1. doi: 10.1097/HEP.0000000000000653. Impact factor: Publication type: Paper in international publication Authors: Alessandria, Carlo; Angeli, Paolo; Bhamidimarri, Kalyan Ram; Bruns, Tony; Caraceni, Paolo; Colombato, Luis; Durand, Francois; Elkrief, Laure; Fassio, Eduardo; Fernandez, Javier et al. DOI: 10.1097/HEP.0000000000000653
PMID: 38068330 Journal: Journal of Clinical Medicine Year: 2023 Reference: J Clin Med. 2023 Nov 24;12(23):7276. doi: 10.3390/jcm12237276. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Ferrer-Costa, Roser; Gabriel-Medina, Pablo; Guerrero, Rafael A; Jimenez-Masip, Alba; Marco, Andres; Munoz-Martinez, Sergio; On Behalf Of The Prisonafld Study Group Collaborators; Pericas, Juan M; Rivera-Esteban, Jesus et al. DOI: 10.3390/jcm12237276
PMID: 38100141 Journal: LIVER INTERNATIONAL Year: 2023 Reference: Liver Int. 2023 Dec 15. doi: 10.1111/liv.15777. Impact factor: Publication type: Paper in international publication Authors: Baliellas, Carme; Castells, Lluis; Crespo, Gonzalo; Fabrega, Emilio; Forns, Xavier; Garcia-Eliz, Maria; Gomez Bravo, Miguel A; Gonzalez Dieguez, Maria L; Lens, Sabela; Loinaz, Carmelo et al. DOI: 10.1111/liv.15777
Preliminary study results confirm that the drug resmetirom reduces the presence of fat, inflammation, cell damage and fibrosis in the liver.
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
The research team used nanotechnology to deliver the drug directly to liver cells, which eliminated side effects without reducing effectiveness.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
