About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37328754 Journal: RESPIRATORY RESEARCH Year: 2023 Reference: Respir Res. 2023 Jun 17;24(1):159. doi: 10.1186/s12931-023-02462-x. Impact factor: Publication type: Paper in international publication Authors: Anon, Jose M; Barbe, Ferran; Barbera, Carmen; Belmonte, Thalia; Benitez, Ivan D; Bermejo-Martin, Jesus F; Bustamante-Munguira, Elena; Caballero, Jesus; Carbonell, Nieves; Ceccato, Adrian et al. DOI: 10.1186/s12931-023-02462-x
PMID: 37572680 Journal: LANCET Year: 2023 Reference: Lancet. 2023 Aug 9:S0140-6736(23)01174-1. doi: 10.1016/S0140-6736(23)01174-1. Impact factor: Publication type: Paper in international publication Authors: Allen, Alina; Alvarez, Marife; Andersen, Peter; Angeli, Paolo; Angeli, Paolo; Ardevol, Alba; Arslanow, Anita; Arslanow, Anita; Beggiato, Luca; Ben Abdesselam, Zahia et al. DOI: 10.1016/S0140-6736(23)01174-1
PMID: 37569568 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Jul 29;24(15):12183. doi: 10.3390/ijms241512183. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Borras, Francesc E; Burgui, Idoia; Camos, Silvia; Corrales, Irene; Costafreda, Maria Isabel; Domingo, Esteban; Esteban, Juan Ignacio; Llorens-Revull, Meritxell; Martinez-Gonzalez, Brenda et al. DOI: 10.3390/ijms241512183
PMID: 37593971 Journal: TRANSFUSION Year: 2023 Reference: Transfusion. 2023 Aug 18. doi: 10.1111/trf.17498. Impact factor: Publication type: Letter or abstract Authors: Alvarez Arguelles, Marta Elena; Garcia-Gala, Jose Maria; Mata, Pablo; Munoz, Maria Del Carmen; Ojea, Ana Maria; Quer Sivila, Josep; Quer Sivila, Josep; Rando Segura, Ariadna; Rodriguez, Mercedes; Rodriguez-Frias, Francisco et al. DOI: 10.1111/trf.17498
PMID: 35676871 Journal: TRANSPLANTATION Year: 2022 Reference: Transplantation. 2022 Sep 1;106(9):1738-1744. doi: 10.1097/TP.0000000000004183. Epub 2022 Aug 19. Impact factor: Publication type: Review in international publication Authors: Alconchel, Felipe; Bhangui, Prashant; Campos-Varela, Isabel; Chadha, Ryan; Chan, Albert; De Martin, Eleonora; Goldaracena, Nicolas; Hessheimer, Amelia; Kabacam, Gokhan; Kalisvaart, Marit et al. DOI: 10.1097/TP.0000000000004183
PMID: 34226786 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2022 Reference: Arch Bronconeumol. 2022 Jun;58(6):520-522. doi: 10.1016/j.arbres.2021.05.027. Epub 2021 Jun 18. Impact factor: Publication type: Letter whit IF Authors: Barbeta, Enric; Cilloniz, Catia; Gabarrus, Albert; Pericas, Juan M; Peroni, Hector; Torres, Antoni et al. DOI: 10.1016/j.arbres.2021.05.027
PMID: 34544604 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Jun 10;158(11):509-518. doi: 10.1016/j.medcli.2021.06.012. Epub 2021 Jun 18. Impact factor: Publication type: Paper in national publication Authors: Almirante, Benito; Anton, Andres; Augustin, Salvador; Bosch-Nicolau, Pau; Dura, Xavier; Eremiev-Eremiev, Simeon; Espinosa-Pereiro, Juan; Fernandez-Hidalgo, Nuria; Guillen-Del-Castillo, Alfredo; Miarons, Marta et al. DOI: 10.1016/j.medcli.2021.06.012
PMID: 35658996 Journal: LANCET Year: 2022 Reference: Lancet. 2022 Jun 4;399(10341):2155. doi: 10.1016/S0140-6736(22)00915-1. Impact factor: Publication type: Letter or abstract Authors: Aceituno, Laia; Aleman, Carmen; Banares, Juan; Escobar, Eduardo Dacosta; Jimenez, Alba; Maynard, Avonello et al. DOI: 10.1016/S0140-6736(22)00915-1
PMID: 34041466 Journal: JHEP Reports Year: 2021 Reference: JHEP Rep. 2021 Mar 17;3(3):100280. doi: 10.1016/j.jhepr.2021.100280. eCollection 2021 Jun. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Esteban, Rafael; Nader, Fatema; Palom, Adriana; Riveiro-Barciela, Mar; Roade, Luisa; Stepanova, Maria; Younossi, Zobair et al. DOI: 10.1016/j.jhepr.2021.100280
PMID: 34014280 Journal: Disease Models & Mechanisms Year: 2021 Reference: Dis Model Mech. 2021 May 1;14(5). pii: 268318. doi: 10.1242/dmm.048884. Epub 2021 May 20. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Barbera, Aurora; Bravo, Miren; Estrella, Federico; Genesca, Joan; Gil, Mar; Hide, Diana; Martell, Maria; Raurell, Imma; Salcedo, Maria Teresa et al. DOI: 10.1242/dmm.048884
PMID: 33992698 Journal: JOURNAL OF HEPATOLOGY Year: 2021 Reference: J Hepatol. 2021 Oct;75(4):865-878. doi: 10.1016/j.jhep.2021.04.049. Epub 2021 May 13. Impact factor: Publication type: Paper in international publication Authors: Alves, Venancio A; Andreu-Oller, Carmen; Boffetta, Paolo; Carrilho, Flair J; Chang, Charissa; Dufour, Jean-Francois; Faure-Dupuy, Suzanne; Friedman, Scott L; Heikenwalder, Mathias; Lachenmayer, Anja et al. DOI: 10.1016/j.jhep.2021.04.049
PMID: 33999179 Journal: JOURNAL OF INFECTIOUS DISEASES Year: 2021 Reference: J Infect Dis. 2021 Dec 1;224(11):1890-1899. doi: 10.1093/infdis/jiab241. Impact factor: Publication type: Paper in international publication Authors: Accarino, Elena Vargas; Buti, Maria; Chen, Chien-Hung; Cheung, Ka-Shing; Cheung, Ramsey; Chuang, Wan-Long; Dai, Chia-Yen; Enomoto, Masaru; Hoang, Joseph; Hsu, Yao-Chun et al. DOI: 10.1093/infdis/jiab241
PMID: 32387080 Journal: TRANSPLANTATION PROCEEDINGS Year: 2020 Reference: Transplant Proc. 2020 Jun;52(5):1442-1449. doi: 10.1016/j.transproceed.2020.02.061. Epub 2020 May 6. Impact factor: Publication type: Paper in international publication Authors: Bilbao, Itxarone; Campos-Varela, Isabel; Caralt, Mireia; Castells, Lluis; Charco, Ramon; Dopazo, Cristina; Gomez-Gavara, Concepcion; Hidalgo, Ernest; Pando, Elizabeth; Pando, Elizabeth et al. DOI: 10.1016/j.transproceed.2020.02.061
PMID: 32376409 Journal: GASTROENTEROLOGY Year: 2020 Reference: Gastroenterology. 2020 Aug;159(2):534-548.e11. doi: 10.1053/j.gastro.2020.04.058. Epub 2020 May 4. Impact factor: Publication type: Paper in international publication Authors: Aigner, Elmar; Anstee, Quentin M; Bals, Robert; Bantel, Heike; Benini, Federica; Bewersdorf, Lisa; Burbaum, Barbara; Carvao, Joana; Chorostowska-Wynimko, Joanna; Datz, Christian et al. DOI: 10.1053/j.gastro.2020.04.058
PMID: 32344934 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Apr 25;9(5). pii: jcm9051246. doi: 10.3390/jcm9051246. Impact factor: Publication type: Paper in international publication Authors: Burgos, Joaquin; Crespo, Manuel; Curran, Adrian; Falco, Vicenc; Martin-Castillo, Mario; Navarro, Jordi; Peraire, Joaquim; Planas, Bibiana; Ribera, Esteban; Rull, Anna et al. DOI: 10.3390/jcm9051246
PMID: 32343960 Journal: GASTROENTEROLOGY Year: 2020 Reference: Gastroenterology. 2020 Aug;159(2):521-533.e9. doi: 10.1053/j.gastro.2020.04.036. Epub 2020 Apr 25. Impact factor: Publication type: Paper in international publication Authors: Bourgeois, Stefan; Buti, Maria; Crespo, Javier; Fry, John; Lenz, Oliver; Moscalu, Iurie; Pascasio, Juan Manuel; Sarrazin, Christoph; Shukla, Umesh; Streinu-Cercel, Adrian et al. DOI: 10.1053/j.gastro.2020.04.036
PMID: 30693573 Journal: HEPATOLOGY Year: 2019 Reference: Hepatology. 2019 Jun;69(6):2349-2363. doi: 10.1002/hep.30527. Epub 2019 Mar 14. Impact factor: Publication type: Paper in international publication Authors: Ackaert, Oliver; Aghemo, Alessio; Beumont, Maria; Biermer, Michael; Bourgeois, Stefan; Buggisch, Peter; Buti, Maria; Corbett, Chris; Fevery, Bart; Greenbloom, Susan et al. DOI: 10.1002/hep.30527
PMID: 30472089 Journal: EBioMedicine Year: 2019 Reference: EBioMedicine. 2019 Jan;39:348-357. doi: 10.1016/j.ebiom.2018.11.023. Epub 2018 Nov 22. Impact factor: Publication type: Paper in international publication Authors: Bosch, Albert; Cayla, Joan A; Garcia-Cehic, Damir; Gregori, Josep; Guix, Susana; Manzanares-Laya, Sandra; Pinto, Rosa M; Pumarola, Tomas; Quer, Josep; Sabria, Aurora et al. DOI: 10.1016/j.ebiom.2018.11.023
PMID: 30684506 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 May;70(5):874-884. doi: 10.1016/j.jhep.2019.01.005. Epub 2019 Jan 24. Impact factor: Publication type: Paper in international publication Authors: Ayuso, Carmen; Belmonte, Ernest; Bruix, Jordi; Calleja, Jose Luis; Carrion, Jose Antonio; Coll, Susana; Darnell, Anna; de Lope, Carlos Rodriguez; Diaz, Alba; Forns, Xavier et al. DOI: 10.1016/j.jhep.2019.01.005
PMID: 30014491 Journal: HEPATOLOGY Year: 2019 Reference: Hepatology. 2019 Jan;69(1):455-457. doi: 10.1002/hep.30180. Epub 2018 Dec 28. Impact factor: Publication type: Paper in international publication Authors: Alvarado, Edilmar; Flavia, Montse; Gely, Cristina; Guarner, Carlos; Poca, Maria; Roman, Eva; Soriano, German; Vargas, Victor et al. DOI: 10.1002/hep.30180
PMID: 29481821 Journal: JOURNAL OF HEPATOLOGY Year: 2018 Reference: J Hepatol. 2018 Jul;69(1):11-17. doi: 10.1016/j.jhep.2018.02.012. Epub 2018 Mar 2. Impact factor: Publication type: Paper in international publication Authors: Baliellas, Carme; Castellote, Jose; Castells, Lluis; Crespo, Gonzalo; Forns, Xavier; Londono, Maria-Carlota; Mauro, Ezequiel; Navasa, Miquel; Tort, Jaume; Trota, Nuria et al. DOI: 10.1016/j.jhep.2018.02.012
PMID: 29472014 Journal: Radiologia Year: 2018 Reference: Radiologia. 2018 Jul - Aug;60(4):290-300. doi: 10.1016/j.rx.2017.12.010. Epub 2018 Feb 19. Impact factor: Publication type: Paper in national publication Authors: Augustin, S; Conangla-Planes, M; Persiva, O; Serres, X et al. DOI: 10.1016/j.rx.2017.12.010
PMID: 29456407 Journal: WORLD JOURNAL OF GASTROENTEROLOGY Year: 2018 Reference: World J Gastroenterol. 2018 Feb 14;24(6):680-692. doi: 10.3748/wjg.v24.i6.680. Impact factor: Publication type: Paper in international publication Authors: Belmonte, Irene; Buti, Maria; Casillas, Rosario; Cortese, Maria Francesca; Esteban, Rafael; Gonzalez, Carolina; Gregori, Josep; Lopez, Rosa Maria; Quer, Josep; Riveiro-Barciela, Mar et al. DOI: 10.3748/wjg.v24.i6.680
PMID: 29460201 Journal: QUALITY OF LIFE RESEARCH Year: 2018 Reference: Qual Life Res. 2018 Jun;27(6):1513-1520. doi: 10.1007/s11136-018-1813-8. Epub 2018 Feb 19. Impact factor: Publication type: Paper in international publication Authors: Adebayo, Danielle; Angeli, Paolo; Bureau, Christophe; Capel, Jeroen; Cordoba, Juan; Elkrief, Laure; Jalan, Rajiv; MacDonald, Stewart; McCune, Anne; Nader, Fatema et al. DOI: 10.1007/s11136-018-1813-8
PMID: 28189751 Journal: JOURNAL OF HEPATOLOGY Year: 2017 Reference: J Hepatol. 2017 Jun;66(6):1138-1148. doi: 10.1016/j.jhep.2017.01.028. Epub 2017 Feb 9. Impact factor: Publication type: Paper in international publication Authors: Albillos, Agustin; Ampuero, Javier; Arenas, Juan; Banares, Rafael; Calleja, Jose Luis; Crespo, Javier; Diago, Moises; Fernandez, Inmaculada; Garcia-Eliz, Maria; Garcia-Samaniego, Javier et al. DOI: 10.1016/j.jhep.2017.01.028
PMID: 28288829 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Nov;23(11):860-867. doi: 10.1016/j.cmi.2017.03.003. Epub 2017 Mar 11. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Buti, Maria; Casillas, Rosario; Esteban, Rafael; Homs, Maria; Nieto, Leonardo; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz, Alicia; Sauleda, Silvia et al. DOI: 10.1016/j.cmi.2017.03.003
PMID: 28279536 Journal: MEDICINA CLINICA Year: 2017 Reference: Med Clin (Barc). 2017 Jul 21;149(2):61-71. doi: 10.1016/j.medcli.2016.12.048. Epub 2017 Mar 7. Impact factor: Publication type: Paper in national publication Authors: Andreu, Victoria; Aracil, Carles; Arenas, Juan I; Bruix, Jordi; Crespo, Javier; Duenas, Eva; F Castroagudin, Javier; Ferrer, Maria Teresa; Forne, Montserrat; Fuentes, Javier et al. DOI: 10.1016/j.medcli.2016.12.048
PMID: 28275194 Journal: JOURNAL OF VIROLOGY Year: 2017 Reference: J Virol. 2017 Apr 28;91(10). pii: JVI.02505-16. doi: 10.1128/JVI.02505-16. Print 2017 May 15. Impact factor: Publication type: Paper in international publication Authors: Beach, Nathan M; Castro, Victoria; Domingo, Esteban; Esteban, Juan Ignacio; Gallego, Isabel; Gastaminza, Pablo; Gomez, Jordi; Gregori, Josep; Lucia-Sanz, Adriana; Manrubia, Susanna C et al. DOI: 10.1128/JVI.02505-16
PMID: 27037760 Journal: Transplant Infectious Disease Year: 2016 Reference: Transpl Infect Dis. 2016 Jun;18(3):442-445. doi: 10.1111/tid.12538. Epub 2016 Jun 9. Impact factor: Publication type: Paper in international publication Authors: Castells, L; Crespo, M; Esteban, J I; Esteban, R; Llaneras, J; Puig, T; Santos, B et al. DOI: 10.1111/tid.12538
PMID: 27008918 Journal: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Year: 2016 Reference: J Gastroenterol Hepatol. 2016 Nov;31(11):1882-1887. doi: 10.1111/jgh.13377. Impact factor: Publication type: Paper in international publication Authors: Arends, Pauline; Berg, Thomas; Brown, Ashley; Buti, Maria; Carey, Ivana; Chi, Heng; de Knegt, Robert J; Deterding, Katja; Fasano, Massimo; Hansen, Bettina et al. DOI: 10.1111/jgh.13377
PMID: 26678008 Journal: JOURNAL OF HEPATOLOGY Year: 2016 Reference: J Hepatol. 2016 Apr;64(4):800-6. doi: 10.1016/j.jhep.2015.11.035. Epub 2015 Dec 8. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Calleja, Jose Luis; Chi, Heng; Colombo, Massimo; Dalekos, George; de la Revilla, Juan; Esteban, Rafael; Galanis, Kostantinos; Gatselis, Nikolaos; Goulis, John et al. DOI: 10.1016/j.jhep.2015.11.035
PMID: 26626497 Journal: JOURNAL OF HEPATOLOGY Year: 2016 Reference: J Hepatol. 2016 Apr;64(4):773-80. doi: 10.1016/j.jhep.2015.11.012. Epub 2015 Dec 2. Impact factor: Publication type: Paper in international publication Authors: Asselah, Tarik; Berg, Thomas; Bornstein, Jeffrey D; Buti, Maria; Dinh, Phillip; Flisiak, Robert; Fung, Scott; Gordon, Stuart C; Janssen, Harry L A; Lampertico, Pietro et al. DOI: 10.1016/j.jhep.2015.11.012
PMID: 25179493 Journal: DIGEST DIS SCI Year: 2015 Reference: Dig Dis Sci. 2015 Jan;60(1):260-8. doi: 10.1007/s10620-014-3336-7. Epub 2014 Sep 2. Impact factor: Publication type: Paper in international publication Authors: Buti, Maria; Chan, Sing; Charuworn, Prista; Dinh, Phillip; Flaherty, John F; Gane, Edward; Kitrinos, Kathryn M; Lee, Samuel S; Marcellin, Patrick; Subramanian, G Mani et al. DOI: 10.1007/s10620-014-3336-7
PMID: 25378574 Journal: J CLIN MICROBIOL Year: 2015 Reference: J Clin Microbiol. 2015 Jan;53(1):219-26. doi: 10.1128/JCM.02093-14. Epub 2014 Nov 5. Impact factor: Publication type: Paper in international publication Authors: Allende, Helena; Alvarez-Tejado, Miguel; Belmonte, Irene; Bes, Marta; Blasi, Maria; Briones, Carlos; Buti, Maria; Caballero, Andrea; Casillas, Rosario; Castells, LLuis et al. DOI: 10.1128/JCM.02093-14
PMID: 25341057 Journal: EUR J GASTROEN HEPAT Year: 2015 Reference: Eur J Gastroenterol Hepatol. 2015 Jan;27(1):46-54. doi: 10.1097/MEG.0000000000000195. Impact factor: Publication type: Paper in international publication Authors: Andrade, Raul; Arenas, Juan I; Bonet, Lucia; Buti, Maria; Calleja, Jose L; Castellano, Gregorio; Delgado, Manuel; Diago, Moises; Gallego, Adolfo; Garcia-Buey, Luisa et al. DOI: 10.1097/MEG.0000000000000195
PMID: 25359351 Journal: EUR RESPIR J Year: 2015 Reference: Eur Respir J. 2015 Mar;45(3):726-37. doi: 10.1183/09031936.00095214. Epub 2014 Oct 30. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Caralt, Berta; Gavalda, Joan; Lopez, Iker; Rello, Jordi; Riera, Jordi; Roman, Antonio et al. DOI: 10.1183/09031936.00095214
PMID: 24389655 Journal: BIOINFORMATICS Year: 2014 Reference: Bioinformatics. 2014 Apr 15;30(8):1104-1111. doi: 10.1093/bioinformatics/btt768. Epub 2014 Jan 2. Impact factor: 4.621 Publication type: Paper in international publication Authors: Quer, Josep, Sanchez, Alex, Gregori, Josep, Salicru, Miquel, Domingo, Esteban, Rodriguez-Frias, Francisco et al. DOI: 10.1093/bioinformatics/btt768
The consensus establishes recommendations that could correct the current disparities related to muscle mass, weight and height and would allow for more precise prioritization of patients who require transplants more urgently.
Using computed tomography (CT), with or without contrast, it is possible to perform an accurate and safe detection of the disease without the need for biopsies and avoiding the limitations of other non-invasive diagnostic tools.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.