About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Liver Diseases group is a referent at the local, national and international level in research, and is one of the most active groups in clinical research at VHIR. The group's prominent involvement in clinical trials is a clear indication of our professionals' commitment to ensuring that patients have access to state-of-the-art therapies. Our participation and collaboration in international projects and consortiums are also a fundamental characteristic of the group. The main objective of the group is to become one of the best translational research groups in liver diseases. It is essential to be able to apply all the findings of basic research to clinical research to improve the health of patients with liver disease.
PMID: 37942255 Journal: Frontiers in Public Health Year: 2023 Reference: Front Public Health. 2023 Oct 24;11:1265323. doi: 10.3389/fpubh.2023.1265323. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Aixut, Sandra; Bargues, Ma Dolores; Bocanegra, Cristina; de Pando, Thais; Elvira, David; Espiau, Maria; Gay, Daniel; Martinez-Camprecios, Joan; Mas-Coma, Santiago; Molina, Israel et al. DOI: 10.3389/fpubh.2023.1265323
PMID: 37963304 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2023 Reference: J Clin Oncol. 2023 Nov 14:JCO2300339. doi: 10.1200/JCO.23.00339. Impact factor: Publication type: Paper in international publication Authors: Agarwal, Neeraj; Augustin, Salvador; Barnicle, Alan; Chi, Kim N; Ciudin, Andreea; de Bono, Johann S; Ferrer-Costa, Roser; Fizazi, Karim; Gabriel-Medina, Pablo; Hussain, Maha et al. DOI: 10.1200/JCO.23.00339
PMID: 37962077 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2023 Reference: N Engl J Med. 2023 Nov 13. doi: 10.1056/NEJMoa2306185. Impact factor: Publication type: Paper in international publication Authors: Addy, Carol; Akarca, Ulus S; Allende, Daniela S; Allende, Daniela S; Alvares-da-Silva, Mario Reis; Amaddeo, Giuliana; Andreone, Pietro; Argemi, Josepmaria; Argemi, Josepmaria; Arrese, Marco et al. DOI: 10.1056/NEJMoa2306185
PMID: 37968020 Journal: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Year: 2023 Reference: J Am Coll Cardiol. 2023 Nov 21;82(21):2031-2033. doi: 10.1016/j.jacc.2023.09.810. Impact factor: Publication type: Editorail in international publication Authors: Addy, Carol; Akarca, Ulus S; Alvares-da-Silva, Mario Reis; Andreone, Pietro; Arrese, Marco; Barrabes, Jose A; Bowlus, Christopher L; Corpechot, Christophe; Dietrich, Julie; Francque, Sven M et al. DOI: 10.1016/j.jacc.2023.09.810
PMID: 35215809 Journal: Viruses-Basel Year: 2022 Reference: Viruses. 2022 Jan 22;14(2). pii: v14020215. doi: 10.3390/v14020215. Impact factor: 5.048 Publication type: Paper in international publication Authors: Rodriguez-Frias, Francisco, Pacin-Ruiz, Beatriz, Cortese, Maria Francesca, Tabernero, David, Sopena, Sara, Gregori, Josep, Garcia-Garcia, Selene, Najarro, Adrian, Aldama, Unai, Palom, Adriana et al. DOI: 10.3390/v14020215
PMID: 35175189 Journal: Blood Transfusion Year: 2022 Reference: Blood Transfus. 2022 Feb 4. pii: 2022.0232-21. doi: 10.2450/2022.0232-21. Impact factor: 3.443 Publication type: Paper in international publication Authors: Jane, Mireia, Ciruela, Pilar, Basile, Luca, Martinez, Ana, Puig, Lluis, Bes, Marta, Sauleda, Silvia, Piron, Maria et al. DOI: 10.2450/2022.0232-21
PMID: 35086339 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2022 Reference: Rev Esp Enferm Dig. 2022 Jan 28. doi: 10.17235/reed.2022.8388/2021. Impact factor: 2.086 Publication type: Paper in international publication Authors: Alcala-Gonzalez, Luis, Cortina, Vicente, Jimenez, Alba, Cerda, Maria, Johansson, Erik, Olivera, Pavel, Santamaria, Amparo, Alonso-Cotoner, Carmen, Jimenez, Cesar et al. DOI: 10.17235/reed.2022.8388/2021
PMID: 34758113 Journal: HEPATOLOGY Year: 2022 Reference: Hepatology. 2022 Feb;75(2):501-502. doi: 10.1002/hep.32227. Epub 2021 Dec 18. Impact factor: 17.425 Publication type: Letter or abstract Authors: Tabernero, David, Cortese, Maria Francesca, Rando-Segura, Ariadna, Buti, Maria, Rodriguez-Frias, Francisco et al. DOI: 10.1002/hep.32227
Preliminary study results confirm that the drug resmetirom reduces the presence of fat, inflammation, cell damage and fibrosis in the liver.
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
The research team used nanotechnology to deliver the drug directly to liver cells, which eliminated side effects without reducing effectiveness.
Des de Vall d'Hebron estem buscant 200 persones voluntàries sanes d'entre 18 i 30 anys per a participar en un estudi sobre els patrons de consum habitual de l'alcohol en població jove, en el marc del projecte StopALD.
