About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.
IP: Oriol Bestard Matamoros Collaborators: Juliana Esperalba Esquerra, Joana Sellarés Roig, Emma Pardo De los Santos, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, Narcís Saubí Roca Funding agency: Instituto de Salud Carlos III Funding: 174240 Reference: PI22/01019 Duration: 01/01/2023 - 31/12/2025
IP: Maria Jose Soler Romeo Collaborators: - Funding agency: EUROPEAN COMMISSION Funding: 0.01 Reference: EC / COST-ACTION / 2020 / SOLER Duration: 12/10/2020 - 11/10/2024
IP: Maria Jose Soler Romeo Collaborators: Francesc Moreso Mateos, Oriol Bestard Matamoros, Joana Sellarés Roig, Irina Betsabe Torres Rodriguez, Concepció Jacobs Cachá, Maria Antonia Emilia Meneghini Funding agency: Instituto de Salud Carlos III Funding: 105765 Reference: RD21/0005/0016 Duration: 01/01/2022 - 31/12/2024
IP: Oriol Bestard Matamoros Collaborators: - Funding agency: Instituto de Salud Carlos III Funding: 158886.66 Reference: PI19/01710 Duration: 01/04/2021 - 30/06/2024
PMID: 37862791 Journal: Gynecologic Oncology Year: 2023 Reference: Gynecol Oncol. 2023 Oct 18;178:119-129. doi: 10.1016/j.ygyno.2023.09.012. Impact factor: Publication type: Paper in international publication Authors: Birrer, Michael; Boixadera, A; Castany-Aregall, M; Colombo, Nicoletta; Cristescu, Razvan; Distefano, L; Edmondson, Mackenzie; Garcia-Arumi, J; Garrell-Salat, X; Gonzalez-Martin, Antonio et al. DOI: 10.1016/j.ygyno.2023.09.012
PMID: 37879444 Journal: ANNALS OF ONCOLOGY Year: 2023 Reference: Ann Oncol. 2023 Oct 17:S0923-7534(23)04281-3. doi: 10.1016/j.annonc.2023.10.117. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Azuma, K; Baneras, Jordi; Barala, P; Bauml, J M; Bearz, A; Boixadera, Anna; Bourla, A B; Califano, R; Campelo, R G et al. DOI: 10.1016/j.annonc.2023.10.117
PMID: 38012160 Journal: Nature Communications Year: 2023 Reference: Nat Commun. 2023 Nov 27;14(1):7770. doi: 10.1038/s41467-023-43652-x. Impact factor: Publication type: Paper in international publication Authors: Alonso, Fabiola; Arpa, Berta; Aunon, Pilar; Corral-Pujol, Marta; Cosovanu, Catalina; Egia-Mendikute, Leire; Garcia, Patricia; Garcia-Carro, Clara; Gutierrez, Eduardo; Manichanh, Chaysavanh et al. DOI: 10.1038/s41467-023-43652-x
PMID: 38020746 Journal: TRANSPLANT INTERNATIONAL Year: 2023 Reference: Transpl Int. 2023 Nov 7;36:11963. doi: 10.3389/ti.2023.11963. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Bestard, Oriol; Couzi, Lionel; Del Carmen, Amin; Fernandez-Ruiz, Mario; Garnacho-Castano, Manuel V; Kaminski, Hannah; Manuel, Oriol; Miravitlles, Marc; Moreno, Eva; Pleguezuelos, Eulogio et al. DOI: 10.3389/ti.2023.11963
PMID: 35629041 Journal: Journal of Clinical Medicine Year: 2022 Reference: J Clin Med. 2022 May 21;11(10). pii: jcm11102915. doi: 10.3390/jcm11102915. Impact factor: 4.242 Publication type: Paper in international publication Authors: Blasco, Miquel, Quintana, Luis F, Shabaka, Amir, Rabasco, Cristina, Draibe, Juliana, Merino, Ana, Melero, Maria Rosa, Alonso, Fabiola, Buxeda, Anna, Batalha, Paula et al. DOI: 10.3390/jcm11102915
PMID: 33533909 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Mar 25;37(4):697-704. doi: 10.1093/ndt/gfab020. Impact factor: 5.992 Publication type: Paper in international publication Authors: Rodriguez, Eva, Latzke, Belen, Sierra, Milagros, Romera, Ana Maria, Siedel, Diego, Agraz, Irene, Soler, Maria Jose, Garcia-Carro, Clara, Draibe, Juliana, de la Prada, Francisco Jose et al. DOI: 10.1093/ndt/gfab020
PMID: 35583251 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 May 18. pii: 6588052. doi: 10.1093/ndt/gfac185. Impact factor: 5.992 Publication type: Paper in international publication Authors: Segarra, Alfons, Garcia, Alicia, Abo, Anabel, Gonzalez, Jorge, Jatem, Elias, Roig, Jordi, Valtierra, Naiara, Ostos, Elena, Santacana, Maria et al. DOI: 10.1093/ndt/gfac185
PMID: 35551070 Journal: Clinical Journal of the American Society of Nephro Year: 2022 Reference: Clin J Am Soc Nephrol. 2022 Jun;17(6):872-876. doi: 10.2215/CJN.01770222. Epub 2022 May 12. Impact factor: 8.237 Publication type: Letter whit IF Authors: Puerta Carretero, Marta, Jaldo Rodriguez, Maria Teresa, Carnerero Di Riso, Manuel Antonio, Martinez, Shaira, Gonzalez, Carmen Calderon, Cervienka, Michal, Macias Carmona, Nicolas, Arroyo, David, Perez Del Valle, Katia M, de Arriba, Gabriel et al. DOI: 10.2215/CJN.01770222
PMID: 34289072 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Sep 27;36(10):1950-1954. doi: 10.1093/ndt/gfab227. Impact factor: 5.992 Publication type: Letter whit IF Authors: Soler, Maria Jose, Toapanta, Nestor, Bestard, Oriol et al. DOI: 10.1093/ndt/gfab227
PMID: 34250317 Journal: Kidney International Reports Year: 2021 Reference: Kidney Int Rep. 2021 Sep;6(9):2305-2315. doi: 10.1016/j.ekir.2021.06.023. Epub 2021 Jul 6. Impact factor: 4.164 Publication type: Paper in international publication Authors: Lopez, Veronica, Buxeda, Anna, Arias-Cabrales, Carlos, Perez-Saez, Maria Jose, Cacho, Judit, Pelegrin, Sheila Cabello, Melilli, Edoardo, Aladren, Maria Jose, Galeano, Cristina, Lorenzo, Inmaculada et al. DOI: 10.1016/j.ekir.2021.06.023
PMID: 34238673 Journal: Hipertension y riesgo vascular Year: 2021 Reference: Hipertens Riesgo Vasc. 2021 Oct-Dec;38(4):201-205. doi: 10.1016/j.hipert.2021.05.003. Epub 2021 Jul 6. Impact factor: 0 Publication type: Letter or abstract Authors: Bury, R, Leon Roman, J, Casteras, A, Vergara, A, Biagetti, B, Garcia-Carro, C, Cordero-Vazquez, E, Hernandez Hernandez, I, Agraz, I, Soler, M J et al. DOI: 10.1016/j.hipert.2021.05.003
PMID: 34241988 Journal: TRANSPLANTATION Year: 2021 Reference: Transplantation. 2021 Oct 1;105(10):2146-2155. doi: 10.1097/TP.0000000000003873. Impact factor: 4.939 Publication type: Paper in international publication Authors: Molina, Maria, Vazquez-Sanchez, Teresa, Crespo, Marta, Facundo, Carme, Rodriguez-Ferrero, M feminine Luisa, Ruiz Fuentes, M feminine Carmen, Loinaz, Carmelo, Bernal, Gabriel, Melilli, Edoardo, Bravo, Carlos et al. DOI: 10.1097/TP.0000000000003873
PMID: 32291449 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Jun 1;35(6):1071-1072. doi: 10.1093/ndt/gfaa093. Impact factor: 4.531 Publication type: Letter whit IF Authors: Palau, Vanesa, Riera, Marta, Soler, Maria Jose et al. DOI: 10.1093/ndt/gfaa093
PMID: 31407783 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2020 Reference: Nephrol Dial Transplant. 2020 Apr 1;35(4):552-554. doi: 10.1093/ndt/gfz165. Impact factor: 4.531 Publication type: Editorail in international publication Authors: Stevens, Kate I, Bruchfeld, Annette, Mallamaci, Francesca, Soler, Maria J et al. DOI: 10.1093/ndt/gfz165
PMID: 32272783 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Apr 7;9(4). pii: jcm9041048. doi: 10.3390/jcm9041048. Impact factor: 3.303 Publication type: Paper in international publication Authors: Kronbichler, Andreas, Effenberger, Maria, Shin, Jae Il, Denicolo, Sara, Rudnicki, Michael, Neuwirt, Hannes, Soler, Maria Jose, Stevens, Kate, Bruchfeld, Annette, Tilg, Herbert et al. DOI: 10.3390/jcm9041048
PMID: 32235471 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Mar 30;9(4). pii: jcm9040947. doi: 10.3390/jcm9040947. Impact factor: 3.303 Publication type: Review in international publication Authors: Navarro-Gonzalez, Juan F, Gorriz, Jose Luis, Soler, Maria Jose, D'Marco, Luis, Martinez Castelao, Alberto, Fernandez-Fernandez, Beatriz, Ortiz, Alberto, Gorriz-Zambrano, Carmen, Navarro-Perez, Jorge, Gorgojo-Martinez, Juan Jose et al. DOI: 10.3390/jcm9040947
PMID: 30290959 Journal: NEFROLOGIA Year: 2019 Reference: Nefrologia. 2019 Jan - Feb;39(1):3-10. doi: 10.1016/j.nefro.2018.05.011. Epub 2018 Oct 2. Impact factor: 1.439 Publication type: Paper in national publication Authors: Navarro-Gonzalez, Juan F, Gorriz, Jose Luis, Soler, M Jose, Martinez Martinez-Castelao, Alberto et al. DOI: 10.1016/j.nefro.2018.05.011
PMID: 30496519 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2019 Reference: Nephrol Dial Transplant. 2019 Jan 1;34(1):4-6. doi: 10.1093/ndt/gfy369. Impact factor: 4.198 Publication type: Paper in international publication Authors: Fouque, Denis, Blankestijn, Peter J, Bruchfeld, Annette, Capasso, Giovambattista, Fliser, Danilo, Rychlik, Ivan, Soler, Maria Jose, Spasovski, Goce, Stevens, Kate, Wanner, Christoph et al. DOI: 10.1093/ndt/gfy369
PMID: 30320621 Journal: CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION Year: 2019 Reference: Curr Opin Nephrol Hypertens. 2019 Jan;28(1):1-9. doi: 10.1097/MNH.0000000000000463. Impact factor: 3.013 Publication type: Paper in international publication Authors: Soler, Maria Jose, Valdivielso, Jose Manuel, Jacobs-Cacha, Conxita et al. DOI: 10.1097/MNH.0000000000000463
PMID: 30537648 Journal: JOURNAL OF CLINICAL VIROLOGY Year: 2019 Reference: J Clin Virol. 2019 Jan;110:45-50. doi: 10.1016/j.jcv.2018.11.010. Epub 2018 Dec 1. Impact factor: 3.02 Publication type: Paper in international publication Authors: Len, Oscar, Perello, Manel, Torres, Irina B, Codina, Gemma, Esperalba, Juliana, Sellares, Joana, Moreso, Francesc, Seron, Daniel, Gavalda, Joan, Los-Arcos, Ibai et al. DOI: 10.1016/j.jcv.2018.11.010
PMID: 24879492 Journal: J HYPERTENS Year: 2014 Reference: J Hypertens. 2014 Aug;32(8):1650-7. doi: 10.1097/HJH.0000000000000238. Impact factor: 4.222 Publication type: Paper in international publication Authors: Martinez-Garcia, Miguel-Angel, Tovar, Jose-Luis, Ferrer, Roser, Romero, Odile, Segarra, Alfons, Lloberes, Patricia, Sampol, Gabriel, Espinel, Eugenia, Ramon, Maria-Antonia et al. DOI: 10.1097/HJH.0000000000000238
PMID: 24284518 Journal: KIDNEY INT Year: 2014 Reference: Kidney Int. 2014 May;85(5):1161-8. doi: 10.1038/ki.2013.461. Epub 2013 Nov 27. Impact factor: 8.52 Publication type: Paper in international publication Authors: Trilla, Enric, Sellares, Joana, Morote, Joan, Seron, Daniel, Montero, Angeles, Torres, Irina B, Perello, Manel, Cantarell, Carme, Antonieta Azancot, M, Moreso, Francesc et al. DOI: 10.1038/ki.2013.461
PMID: 24636074 Journal: ACTAS UROL ESP Year: 2014 Reference: Actas Urol Esp. 2014 Oct;38(8):552-6. doi: 10.1016/j.acuro.2014.02.004. Epub 2014 Mar 11. Impact factor: 1.148 Publication type: Paper in national publication Authors: Celma, A, Cantarell, C, Moreso, F, Seron, D, Morote, J, Placer, J, Planas, J, Salvador, C, Lorente, D, Trilla, E et al. DOI: 10.1016/j.acuro.2014.02.004
PMID: 24480289 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 May 6;142(9):393-6. doi: 10.1016/j.medcli.2013.09.044. Epub 2014 Jan 28. Impact factor: 1.252 Publication type: Paper in national publication Authors: Costa-Requena, Gema, Cantarell Aixendri, M Carmen, Rodriguez Urrutia, Amanda, Seron Micas, Daniel et al. DOI: 10.1016/j.medcli.2013.09.044
A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.
An international study involving the Hospital del Mar Research Institute and VHIR shows that there are substantial differences between men and women in the energy metabolism of of renal tubular cells.
Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.
