About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.
Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.
Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.
PMID: 35332927 Journal: REVISTA DE NEUROLOGIA Year: 2022 Reference: Rev Neurol. 2022 Apr 1;74(7):232-241. doi: 10.33588/rn.7407.2021495. Impact factor: 0.87 Publication type: Review in national publication Authors: Llaurado, A, Sanchez-Tejerina, D, Vidal-Taboada, J M, Salvado, M, Sotoca, J, Juntas-Morales, R et al. DOI: 10.33588/rn.7407.2021495
PMID: 35252779 Journal: ACS Applied Nano Materials Year: 2022 Reference: ACS Appl Nano Mater. 2022 Feb 25;5(2):2113-2125. doi: 10.1021/acsanm.1c03837. Epub 2022 Feb 10. Impact factor: 5.097 Publication type: Paper in international publication Authors: Grzelak, Jan, Gazquez, Jaume, Grayston, Alba, Teles, Mariana, Herranz, Fernando, Roher, Nerea, Rosell, Anna, Roig, Anna, Gich, Marti et al. DOI: 10.1021/acsanm.1c03837
PMID: 35226340 Journal: Neurotherapeutics Year: 2022 Reference: Neurotherapeutics. 2022 Mar;19(2):513-527. doi: 10.1007/s13311-022-01203-0. Epub 2022 Feb 28. Impact factor: 7.62 Publication type: Paper in international publication Authors: Valls, Raquel, de Ramon, Helena, Garcia-Rodriguez, Paula, Orset, Cyrille, Artigas, Laura, Sardon, Teresa, Rosell, Anna, Montaner, Joan, Ramiro, Laura, Simats, Alba et al. DOI: 10.1007/s13311-022-01203-0
PMID: 34751541 Journal: INTERNATIONAL ANGIOLOGY Year: 2022 Reference: Int Angiol. 2022 Feb;41(1):1-8. doi: 10.23736/S0392-9590.21.04704-0. Epub 2021 Nov 9. Impact factor: 2.789 Publication type: Paper in international publication Authors: Ruiz-Rodriguez, Juan Carlos, Ferrer, Ricard, DE Nadal, Miriam, Suito-Alcantara, Milagros A, Llagostera, Secundino, Bellmunt, Sergi, Gil, Miquel, Martinez, Lucia, Rodriguez, Manuela, Gil-Sala, Daniel et al. DOI: 10.23736/S0392-9590.21.04704-0
PMID: 34781064 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Dec;125:108395. doi: 10.1016/j.yebeh.2021.108395. Epub 2021 Nov 12. Impact factor: 2.937 Publication type: Paper in international publication Authors: Quintana, Manuel, Fonseca, Elena, Sanchez-Lopez, Javier, Mazuela, Gonzalo, Santamarina, Estevo, Abraira, Laura, Alvarez-Sabin, Jose, Toledo, Manuel et al. DOI: 10.1016/j.yebeh.2021.108395
PMID: 34455823 Journal: STROKE Year: 2021 Reference: Stroke. 2021 Dec;52(12):3908-3917. doi: 10.1161/STROKEAHA.121.034883. Epub 2021 Aug 30. Impact factor: 7.914 Publication type: Paper in international publication Authors: Martinez-Domeno, Alejandro, Prats-Sanchez, Luis, Guasch-Jimenez, Marina, Cardona, Pere, Nunez-Guillen, Ana, Requena, Manuel, Rubiera, Marta, Olive, Marta, Bustamante, Alejandro, Gomis, Meritxell et al. DOI: 10.1161/STROKEAHA.121.034883
PMID: 34375799 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Oct;123:108238. doi: 10.1016/j.yebeh.2021.108238. Epub 2021 Aug 7. Impact factor: 2.937 Publication type: Paper in international publication Authors: Turon, Marc, Jimenez-Balado, Joan, Abraira, Laura, Fonseca, Elena, Toledo, Manuel, Delgado, Pilar, Maisterra, Olga, Salas-Puig, Xavier, Alvarez-Sabin, Jose, Santamarina, Estevo et al. DOI: 10.1016/j.yebeh.2021.108238
PMID: 34338742 Journal: JAMA Neurology Year: 2021 Reference: JAMA Neurol. 2021 Sep 1;78(9):1099-1107. doi: 10.1001/jamaneurol.2021.2385. Impact factor: 18.302 Publication type: Paper in international publication Authors: Requena, Manuel, Olive-Gadea, Marta, Muchada, Marian, Hernandez, David, Rubiera, Marta, Boned, Sandra, Pinana, Carlos, Deck, Matias, Garcia-Tornel, Alvaro, Diaz-Silva, Humberto et al. DOI: 10.1001/jamaneurol.2021.2385
PMID: 31992414 Journal: Journal of Clinical Sleep Medicine Year: 2020 Reference: J Clin Sleep Med. 2020 Feb 15;16(2):243-250. doi: 10.5664/jcsm.8174. Epub 2020 Jan 13. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Sabin, Jose; Delgado, Pilar; Ferre, Alex; Maisterra, Olga; Montaner, Joan; Quintana, Manuel; Riba-Llena, Iolanda; Romero, Odile; Sampol, Gabriel; Santamarina, Estevo et al. DOI: 10.5664/jcsm.8174
PMID: 31958084 Journal: JOURNAL OF ALZHEIMERS DISEASE Year: 2020 Reference: J Alzheimers Dis. 2020;73(4):1585-1595. doi: 10.3233/JAD-190753. Impact factor: Publication type: Paper in international publication Authors: Alcolea, Daniel; Bustamante, Alejandro; Cruchaga, Carlos; Delgado, Pilar; Faura, Julia; Fortea, Juan; Giralt, Dolors; Harari, Oscar; Hernandez-Guillamon, Mar; Ibanez, Laura et al. DOI: 10.3233/JAD-190753
PMID: 31827267 Journal: Nature Reviews Neurology Year: 2020 Reference: Nat Rev Neurol. 2020 Jan;16(1):30-42. doi: 10.1038/s41582-019-0281-2. Epub 2019 Dec 11. Impact factor: Publication type: Review in international publication Authors: Bacskai, Brian J; Greenberg, Steven M; Hernandez-Guillamon, Mar; Pruzin, Jeremy; Sperling, Reisa; van Veluw, Susanne J et al. DOI: 10.1038/s41582-019-0281-2
PMID: 31672489 Journal: NEUROSCIENCE LETTERS Year: 2020 Reference: Neurosci Lett. 2020 Jan 1;714:134580. doi: 10.1016/j.neulet.2019.134580. Epub 2019 Oct 28. Impact factor: Publication type: Paper in international publication Authors: Bustamante, Alejandro; Garcia-Tornel, Alvaro; Mancha, Fernando; Montaner, Joan; Penalba, Anna; Ramiro, Laura; Rovira, Alex; Simats, Alba et al. DOI: 10.1016/j.neulet.2019.134580
PMID: 30582445 Journal: CIRCULATION RESEARCH Year: 2019 Reference: Circ Res. 2019 Jan 4;124(1):114-120. doi: 10.1161/CIRCRESAHA.118.313533. Impact factor: 15.862 Publication type: Paper in international publication Authors: Torres-Aguila, Nuria P, Mola-Caminal, Marina, Carrera, Caty, Soriano-Tarraga, Carolina, Giralt Steinhauer, Eva, Diaz-Navarro, Rosa M, Tur, Silvia, Jimenez, Carmen, Medina-Dols, Aina, Cullell, Natalia et al. DOI: 10.1161/CIRCRESAHA.118.313533
PMID: 31652649 Journal: Cells Year: 2019 Reference: Cells. 2019 Oct 22;8(10). pii: cells8101299. doi: 10.3390/cells8101299. Impact factor: 5.656 Publication type: Paper in international publication Authors: Valls-Lacalle, Laura, Negre-Pujol, Corall, Rodriguez, Cristina, Varona, Saray, Valera-Canellas, Antoni, Consegal, Marta, Martinez-Gonzalez, Jose, Rodriguez-Sinovas, Antonio et al. DOI: 10.3390/cells8101299
PMID: 31590472 Journal: Journal of Stroke Year: 2019 Reference: J Stroke. 2019 Sep;21(3):276-289. doi: 10.5853/jos.2019.01522. Epub 2019 Sep 30. Impact factor: 5.571 Publication type: Review in international publication Authors: Gallego-Fabrega, Cristina, Torres-Aguila, Nuria P, Carrera, Caty, Muino, Elena, Cullell, Natalia, Carcel-Marquez, Jara, Delgado, Pilar, Ibanez, Laura, Heitsch, Laura, Krupinski, Jerzy et al. DOI: 10.5853/jos.2019.01522
PMID: 31059794 Journal: Nanomedicine-Nanotechnology Biology and Medicine Year: 2019 Reference: Nanomedicine. 2019 Aug;20:101986. doi: 10.1016/j.nano.2019.03.008. Epub 2019 May 3. Impact factor: 5.57 Publication type: Paper in international publication Authors: Crich, Simonetta Geninatti, Alberti, Diego, Protti, Nicoletta, Comella, Joan X, Teixidor, Francesc, Rosell, Anna, Vinas, Clara, Grayston, Alba, Galenkamp, Koen M O, Morancho, Anna et al. DOI: 10.1016/j.nano.2019.03.008
PMID: 30172139 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2018 Reference: Seizure. 2018 Oct;61:158-163. doi: 10.1016/j.seizure.2018.08.016. Epub 2018 Aug 18. Impact factor: 2.839 Publication type: Clinical guide Authors: Toledo, M, Salas Puig, X, Abraira Del Fresno, L, Fonseca Hernandez, E, Olive Gadea, M, Requena Ruiz, M, Quintana, M, Santamarina Perez, E, Alvarez Sabin, J et al. DOI: 10.1016/j.seizure.2018.08.016
PMID: 30133323 Journal: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY Year: 2018 Reference: Am J Physiol Cell Physiol. 2018 Nov 1;315(5):C664-C674. doi: 10.1152/ajpcell.00200.2018. Epub 2018 Aug 22. Impact factor: 3.454 Publication type: Paper in international publication Authors: Esquiva, Gema, Grayston, Alba, Rosell, Anna et al. DOI: 10.1152/ajpcell.00200.2018
PMID: 30118928 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2018 Reference: Seizure. 2018 Oct;61:78-82. doi: 10.1016/j.seizure.2018.08.007. Epub 2018 Aug 11. Impact factor: 2.839 Publication type: Paper in international publication Authors: Toledo, Manuel, Fonseca, Elena, Olive, Marta, Requena, Manuel, Quintana, Manuel, Abraira-Del-Fresno, Laura, Salas-Puig, Xavier, Santamarina, Estevo et al. DOI: 10.1016/j.seizure.2018.08.007
PMID: 30093920 Journal: Therapeutic Advances in Neurological Disorders Year: 2018 Reference: Ther Adv Neurol Disord. 2018 Aug 6;11:1756286418789340. doi: 10.1177/1756286418789340. eCollection 2018. Impact factor: 4.75 Publication type: Review in international publication Authors: Ramiro, Laura, Simats, Alba, Garcia-Berrocoso, Teresa, Montaner, Joan et al. DOI: 10.1177/1756286418789340
PMID: 27026631 Journal: STROKE Year: 2016 Reference: Stroke. 2016 May;47(5):1180-6. doi: 10.1161/STROKEAHA.115.012237. Epub 2016 Mar 29. Impact factor: Publication type: Paper in international publication Authors: Carrera, Caty; Cullell, Natalia; Fernandez-Cadenas, Israel; Fontana, Pierre; Gallego-Fabrega, Cristina; Krupinski, Jerzy; Marti-Fabregas, Joan; Montaner, Joan; Muino, Elena; Pera, Joanna et al. DOI: 10.1161/STROKEAHA.115.012237
PMID: 26999113 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2016 Reference: Int J Mol Sci. 2016 Mar 16;17(3). pii: E390. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Sabin, Jose; Jacas, Carlos; Maisterra, Olga; Molina, Carlos; Quintana, Manuel; Santamarina, Estevo et al. DOI: 10.3390/ijms17030390
PMID: 27001146 Journal: NEUROBIOLOGY OF DISEASE Year: 2016 Reference: Neurobiol Dis. 2016 Jul;91:236-46. doi: 10.1016/j.nbd.2016.03.016. Epub 2016 Mar 19. Impact factor: Publication type: Paper in international publication Authors: Barcelo, Veronica; Gabriel-Salazar, Marina; Giralt, Dolors; Ma, Feifei; Montaner, Joan; Morancho, Anna; Rosell, Anna; Segundo, Pablo Martinez-San et al. DOI: 10.1016/j.nbd.2016.03.016
PMID: 26723523 Journal: European Journal of Internal Medicine Year: 2016 Reference: Eur J Intern Med. 2016 Apr;29:9-21. doi: 10.1016/j.ejim.2015.11.030. Epub 2015 Dec 23. Impact factor: Publication type: Review in national publication Authors: Bustamante, Alejandro; Garcia-Berrocoso, Teresa; Llombart, Victor; Molina, Carlos; Montaner, Joan; Ribo, Marc; Rodriguez, Noelia et al. DOI: 10.1016/j.ejim.2015.11.030
PMID: 25466693 Journal: J NEUROL SCI Year: 2015 Reference: J Neurol Sci. 2015 Jan 15;348(1-2):1-2. doi: 10.1016/j.jns.2014.10.038. Epub 2014 Oct 31. Impact factor: Publication type: Editorail in international publication Authors: Montaner, Joan et al. DOI: 10.1016/j.jns.2014.10.038
PMID: 25449044 Journal: MOVEMENT DISORD Year: 2015 Reference: Mov Disord. 2015 Feb;30(2):229-37. doi: 10.1002/mds.26077. Epub 2014 Dec 1. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Miquel; Alvarez, Ramiro; Bayes, Angels; Brucke, Thomas; Callen, Antoni; Compta, Yaroslau; De Fabregues, Oriol; Gaig, Carles; Hofeneder, Dominik; Hotter, Anna et al. DOI: 10.1002/mds.26077
PMID: 25420145 Journal: NAT GENET Year: 2015 Reference: Nat Genet. 2015 Jan;47(1):78-83. doi: 10.1038/ng.3154. Epub 2014 Nov 24. Impact factor: Publication type: Paper in international publication Authors: Abboud, Sherine; Amouyel, Philippe; Arveiler, Dominique; Bartels, Eva; Bejot, Yannick; Beretta, Simone; Bersano, Anna; Bonati, Leo H; Boncoraglio, Giorgio B; Bottcher, Thomas et al. DOI: 10.1038/ng.3154
PMID: 25382311 Journal: PROTEINS Year: 2015 Reference: Proteins. 2015 Jan;83(1):91-104. doi: 10.1002/prot.24708. Epub 2014 Nov 18. Impact factor: Publication type: Paper in international publication Authors: de la Cruz, Xavier; Dominguez, Carmen; Fernandez-Cadenas, Israel; Lois, Sergio; Montaner, Joan; Riera, Casandra; Rodriguez-Sureda, Victor et al. DOI: 10.1002/prot.24708
PMID: 23792330 Journal: Nanomedicine Year: 2014 Reference: Nanomedicine. 2014 Jan;10(1):225-34. doi: 10.1016/j.nano.2013.06.005. Epub 2013 Jun 20. Impact factor: Publication type: Paper in international publication Authors: Barcelo, Veronica; Boada, Cristina; Carenza, Elisa; Laromaine, Anna; Levander, Lisa; Montaner, Joan; Morancho, Anna; Roig, Anna; Rosell, Anna et al. DOI: 10.1016/j.nano.2013.06.005
PMID: 24335228 Journal: STROKE Year: 2014 Reference: Stroke. 2014 Feb;45(2):432-7. doi: 10.1161/STROKEAHA.113.003431. Epub 2013 Dec 12. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Sabin, Jose; Bustamante, Alejandro; Dominguez, Carmen; Eschenfelder, Christoph; Garcia-Berrocoso, Teresa; Giralt, Dolors; Hernandez-Guillamon, Mar; Llombart, Victor; Martin-Gallan, Pilar; Molina, Carlos A et al. DOI: 10.1161/STROKEAHA.113.003431
PMID: 24386991 Journal: JOURNAL OF NEUROCHEMISTRY Year: 2014 Reference: J Neurochem. 2014 May;129(3):463-72. doi: 10.1111/jnc.12649. Epub 2014 Feb 11. Impact factor: Publication type: Paper in international publication Authors: Boada, Cristina; Bustamante, Alejandro; Espadaler, Marc; Garcia-Berrocoso, Teresa; Giralt, Dolors; Llombart, Victor; Molina, Carlos; Montaner, Joan; Penalba, Anna; Rubiera, Marta et al. DOI: 10.1111/jnc.12649
PMID: 25463126 Journal: ATHEROSCLEROSIS Year: 2014 Reference: Atherosclerosis. 2014 Dec;237(2):811-5. doi: 10.1016/j.atherosclerosis.2014.11.003. Epub 2014 Nov 10. Impact factor: 3.971 Publication type: Paper in international publication Authors: Riba-Llena, Iolanda, Penalba, Anna, Pelegri, Dolors, Vilar, Andrea, Jarca, Carme I, Filomena, Josefina, Montaner, Joan, Delgado, Pilar et al. DOI: 10.1016/j.atherosclerosis.2014.11.003
PMID: 21477318 Journal: Nutrition & Metabolism Year: 2011 Reference: Nutr Metab (Lond). 2011 Apr 8;8(1):22. doi: 10.1186/1743-7075-8-22. Impact factor: 2.349 Publication type: Paper in international publication Authors: Joan Sabater, , , , , et al. DOI: 10.1186/1743-7075-8-22
PMID: 20381197 Journal: NEUROBIOLOGY OF AGING Year: 2011 Reference: Neurobiol Aging. 2011 Mar;32(3):551.e13-22. Epub 2010 Apr 9. Impact factor: 6.634 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1016/j.neurobiolaging.2010.01.019
For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.
The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.
The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.
