About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.
Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.
Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.
PMID: 34015572 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2021 Reference: Seizure. 2021 Jul;89:62-64. doi: 10.1016/j.seizure.2021.04.029. Epub 2021 May 11. Impact factor: 3.184 Publication type: Letter whit IF Authors: Vilaseca, Andreu, Fonseca, Elena, Anciones Martin, Carla, Seijo-Raposo, Ivan, Abraira, Laura, Santamarina, Estevo, Quintana, Manuel, Alvarez-Sabin, Jose, Gil-Nagel, Antonio, Toledo, Manuel et al. DOI: 10.1016/j.seizure.2021.04.029
PMID: 33992961 Journal: EPILEPSY & BEHAVIOR Year: 2021 Reference: Epilepsy Behav. 2021 Jul;120:108007. doi: 10.1016/j.yebeh.2021.108007. Epub 2021 May 13. Impact factor: 2.937 Publication type: Paper in international publication Authors: Santamarina, E, Parejo-Carbonell, B, Abraira, L, Gutierrez-Viedma, A, Fonseca, E, Seijo, I, Abarrategui, B, Salas-Puig, X, Quintana, M, Toledo, M et al. DOI: 10.1016/j.yebeh.2021.108007
PMID: 33875301 Journal: NEUROLOGIA Year: 2021 Reference: Neurologia (Engl Ed). 2021 Apr 16. pii: S0213-4853(21)00053-0. doi: 10.1016/j.nrl.2021.02.014. Impact factor: 3.109 Publication type: Paper in national publication Authors: Llaurado, A, Quintana, M, Fonseca, E, Abraira, L, Toledo, M, Requena, M, Olive, M, Ballve, A, Campos, D, Sueiras, M et al. DOI: 10.1016/j.nrl.2021.02.014
PMID: 33583710 Journal: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY Year: 2021 Reference: Eur J Vasc Endovasc Surg. 2021 Apr;61(4):628-634. doi: 10.1016/j.ejvs.2020.12.015. Epub 2020 Dec 23. Impact factor: 7.069 Publication type: Paper in international publication Authors: Ferrer, Ricard, de Nadal, Miriam, Monreal, Manel, Llagostera, Secundino, Ruiz-Rodriguez, Juan Carlos, Gil, Miquel, Martinez-Carnovale, Lucia, Bellmunt-Montoya, Sergi, Riera, Claudia, Gil, Daniel et al. DOI: 10.1016/j.ejvs.2020.12.015
PMID: 33082494 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Oct 20;10(1):17838. doi: 10.1038/s41598-020-74880-6. Impact factor: 3.998 Publication type: Paper in international publication Authors: Lema, Camila, Andres, Mireia, Aguade-Bruix, Santiago, Consegal, Marta, Rodriguez-Sinovas, Antonio, Benito, Begona, Ferreira-Gonzalez, Ignacio, Barba, Ignasi et al. DOI: 10.1038/s41598-020-74880-6
PMID: 33066917 Journal: Journal of Stroke & Cerebrovascular Diseases Year: 2020 Reference: J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105225. doi: 10.1016/j.jstrokecerebrovasdis.2020.105225. Epub 2020 Aug 5. Impact factor: 1.787 Publication type: Paper in international publication Authors: Ribo, Marc, Molina, Carlos A, Tomasello, Alejandro, Rubiera, Marta, Requena, Manuel, Muchada, Marian, Garcia-Tornel, Alvaro, Deck, Matias, Juega, Jesus, Boned, Sandra et al. DOI: 10.1016/j.jstrokecerebrovasdis.2020.105225
PMID: 32907910 Journal: JOURNAL OF INVESTIGATIVE MEDICINE Year: 2020 Reference: J Investig Med. 2020 Dec;68(8):1379-1385. doi: 10.1136/jim-2020-001432. Epub 2020 Sep 8. Impact factor: 2.304 Publication type: Paper in international publication Authors: Cabezas, Juan Antonio, Bustamante, Alejandro, Giannini, Nicola, Pecharroman, Emilio, Katsanos, Aristeidis H, Tsivgoulis, Georgios, Rozanski, Michal, Audebert, Heinrich, Mondello, Stefania, Llombart, Victor et al. DOI: 10.1136/jim-2020-001432
PMID: 32868372 Journal: MOLECULAR & CELLULAR PROTEOMICS Year: 2020 Reference: Mol Cell Proteomics. 2020 Dec;19(12):1921-1935. doi: 10.1074/mcp.RA120.002283. Epub 2020 Aug 31. Impact factor: 4.87 Publication type: Paper in international publication Authors: Montaner, Joan, Bustamante, Alejandro, Simats, Alba, Ramiro, Laura, Garcia-Berrocoso, Teresa, Brianso, Ferran, Gonzalo, Ricardo, Martin, Luna, Sabe, Anna, Gill, Natalia et al. DOI: 10.1074/mcp.RA120.002283
PMID: 31177974 Journal: STROKE Year: 2019 Reference: Stroke. 2019 Jul;50(7):1781-1788. doi: 10.1161/STROKEAHA.119.025088. Epub 2019 Jun 10. Impact factor: 6.046 Publication type: Paper in international publication Authors: Olive-Gadea, Marta, Garcia-Tornel, Alvaro, Requena, Manuel, Rubiera, Marta, Muchada, Marian, Pagola, Jorge, Rodriguez-Luna, David, Deck, Matias, Juega, Jesus, Rodriguez-Villatoro, Noelia et al. DOI: 10.1161/STROKEAHA.119.025088
PMID: 31165904 Journal: CELLULAR AND MOLECULAR LIFE SCIENCES Year: 2019 Reference: Cell Mol Life Sci. 2019 Aug;76(16):3117-3140. doi: 10.1007/s00018-019-03175-5. Epub 2019 Jun 5. Impact factor: 7.014 Publication type: Review in international publication Authors: Montaner, Joan, Ramiro, Laura, Simats, Alba, Hernandez-Guillamon, Mar, Delgado, Pilar, Bustamante, Alejandro, Rosell, Anna et al. DOI: 10.1007/s00018-019-03175-5
PMID: 31079028 Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY Year: 2019 Reference: Seizure. 2019 Jul;69:198-203. doi: 10.1016/j.seizure.2019.04.021. Epub 2019 May 1. Impact factor: 2.765 Publication type: Paper in international publication Authors: Toledo, Manuel, Abraira, Laura, Mazuela, Gonzalo, Quintana, Manuel, Cazorla, Sonia, Santamarina, Estevo et al. DOI: 10.1016/j.seizure.2019.04.021
PMID: 31077261 Journal: Alzheimers Research & Therapy Year: 2019 Reference: Alzheimers Res Ther. 2019 May 10;11(1):42. doi: 10.1186/s13195-019-0498-8. Impact factor: 6.142 Publication type: Paper in international publication Authors: Bonaterra, Anna, Sanchez-Quesada, Jose Luis, Montaner, Joan, Maspoch, Daniel, Cano-Sarabia, Mary, Hernandez-Guillamon, Mar, Colell, Guillem, Sole, Montse, Marazuela, Paula, de Retana, Sofia Fernandez et al. DOI: 10.1186/s13195-019-0498-8
PMID: 29784938 Journal: Scientific Reports Year: 2018 Reference: Sci Rep. 2018 May 21;8(1):7899. doi: 10.1038/s41598-018-26237-3. Impact factor: 4.122 Publication type: Paper in international publication Authors: Simats, Alba, Garcia-Berrocoso, Teresa, Ramiro, Laura, Giralt, Dolors, Gill, Natalia, Penalba, Anna, Bustamante, Alejandro, Rosell, Anna, Montaner, Joan et al. DOI: 10.1038/s41598-018-26237-3
PMID: 29669870 Journal: STROKE Year: 2018 Reference: Stroke. 2018 May;49(5):1279-1281. doi: 10.1161/STROKEAHA.118.020163. Epub 2018 Apr 18. Impact factor: 6.239 Publication type: Paper in international publication Authors: Riba-Llena, Iolanda, Jimenez-Balado, Joan, Castane, Xavier, Girona, Anna, Lopez-Rueda, Antonio, Mundet, Xavier, Jarca, Carmen I, Alvarez-Sabin, Jose, Montaner, Joan, Delgado, Pilar et al. DOI: 10.1161/STROKEAHA.118.020163
PMID: 29531354 Journal: NATURE GENETICS Year: 2018 Reference: Nat Genet. 2018 Apr;50(4):524-537. doi: 10.1038/s41588-018-0058-3. Epub 2018 Mar 12. Impact factor: 27.125 Publication type: Paper in international publication Authors: Haessler, Jeffrey, Brown, Robert D Jr, Butterworth, Adam S, Carrera, Caty, Carty, Cara L, Chasman, Daniel I, Chen, Wei-Min, Cole, John W, Correa, Adolfo, Cotlarciuc, Ioana et al. DOI: 10.1038/s41588-018-0058-3
PMID: 28631309 Journal: JOURNAL OF SLEEP RESEARCH Year: 2018 Reference: J Sleep Res. 2018 Apr;27(2):232-239. doi: 10.1111/jsr.12571. Epub 2017 Jun 20. Impact factor: 3.433 Publication type: Paper in international publication Authors: Montaner, Joan, Alvarez-Sabin, Jose, Romero, Odile, Delgado, Pilar, Quintana, Manuel, Santamarina, Estevo, Ferre, Alex, Maisterra, Olga, Riba-Llena, Iolanda, Sampol, Gabriel et al. DOI: 10.1111/jsr.12571
PMID: 26718731 Journal: Journal of Proteomics Year: 2016 Reference: J Proteomics. 2016 Feb 5;133:100-12. doi: 10.1016/j.jprot.2015.12.011. Epub 2015 Dec 21. Impact factor: Publication type: Paper in international publication Authors: Bech-Serra, Joan Josep; Bustamante, Alejandro; Canals, Francesc; Garcia-Berrocoso, Teresa; Giralt, Dolors; Hernandez-Guillamon, Mar; Llombart, Victor; Montaner, Joan; Reverter-Branchat, Gemma; Simats, Alba et al. DOI: 10.1016/j.jprot.2015.12.011
PMID: 27311989 Journal: Archivos de la Sociedad Espanola de Oftalmologia Year: 2016 Reference: Arch Soc Esp Oftalmol. 2016 Nov;91(11):513-519. doi: 10.1016/j.oftal.2016.05.001. Epub 2016 Jun 13. Impact factor: 0 Publication type: Paper in national publication Authors: Vazquez Dorrego, X M, Manresa Dominguez, J M, Heras Tebar, A, Fores, R, Girona Marce, A, Alzamora Sas, M T, Delgado Martinez, P, Riba-Llena, I, Ugarte Anduaga, J, Beristain Iraola, A et al. DOI: 10.1016/j.oftal.2016.05.001
PMID: 25966945 Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM Year: 2016 Reference: J Cereb Blood Flow Metab. 2016 Jan;36(1):253-63. doi: 10.1038/jcbfm.2015.90. Impact factor: 5.407 Publication type: Paper in international publication Authors: Montaner, Joan, Riba-Llena, Iolanda, Nafria, Cristina, Filomena, Josefina, Tovar, Jose L, Vinyoles, Ernest, Mundet, Xavier, Jarca, Carmen I, Vilar-Bergua, Andrea, Delgado, Pilar et al. DOI: 10.1038/jcbfm.2015.90
PMID: 25899297 Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM Year: 2016 Reference: J Cereb Blood Flow Metab. 2016 Jan;36(1):55-71. doi: 10.1038/jcbfm.2015.68. Impact factor: 5.407 Publication type: Paper in international publication Authors: Vilar-Bergua, A, Riba-Llena, I, Nafria, C, Bustamante, A, Llombart, V, Delgado, P, Montaner, J et al. DOI: 10.1038/jcbfm.2015.68
PMID: 26101344 Journal: HYPERTENSION Year: 2015 Reference: Hypertension. 2015 Sep;66(3):634-40; discussion 445. doi: 10.1161/HYPERTENSIONAHA.115.05440. Epub 2015 Jun 22. Impact factor: 6.48 Publication type: Paper in international publication Authors: Filomena, Josefina, Tovar, Jose L, Mundet, Xavier, Castane, Xavier, Vilar, Andrea, Lopez-Rueda, Antonio, Jimenez-Balado, Joan, Cartanya, Anna, Montaner, Joan, Delgado, Pilar et al. DOI: 10.1161/HYPERTENSIONAHA.115.05440
For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.
The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.
The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.