Neurovascular Diseases

Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.

Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.

Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.

Projects

Aquest any no hi ha projectes actius.

Publications

Common and specific proteins and pathways in heart and cerebral ischemia.

PMID: 37944280
Journal: Journal of Stroke & Cerebrovascular Diseases
Year: 2023
Reference: J Stroke Cerebrovasc Dis. 2023 Nov 7;33(1):107467. doi: 10.1016/j.jstrokecerebrovasdis.2023.107467.
Impact factor:
Publication type: Paper in international publication
Authors: Agudelo, Victor Hugo; Alonso, Javier Robles; Alvarez, Maria Eugenia Vazquez; Amat-Santos, Ignacio J; Andraka, Leire; Anton, Salvador Alvarez; Aquino, Rosa Sanchez; Arellano, Manuel Vizcaino; Arroyo, Jose Ramon Ruiz; Arzamendi, Dabit et al.
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107467

Minimally invasive surgery of the abdominal wall.

PMID: 37951468
Journal: Cirugia espanola
Year: 2023
Reference: Cir Esp (Engl Ed). 2023 Nov 9:S2173-5077(23)00193-X. doi: 10.1016/j.cireng.2023.01.009.
Impact factor:
Publication type: Paper in international publication
Authors: Bustamante, Alejandro; Delgado, Pilar; Escudero-Martinez, Irene; Garcia-Rodriguez, Paula; Guaman-Pilco, Daisy R; Guaman-Pilco, Daisy R; Jimenez-Balado, Joan; Lamana-Vallverdu, Marcel; Lopez Cano, Manuel; Montaner, Joan et al.
DOI: 10.1016/j.cireng.2023.01.009

Diesel exhaust particles exposure exacerbates pro-thrombogenic plasma features ex-vivo after cerebral ischemia and accelerates tPA-induced clot-lysis in hypertensive subjects.

PMID: 37974302
Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Year: 2023
Reference: J Cereb Blood Flow Metab. 2023 Nov 16:271678X231214826. doi: 10.1177/0271678X231214826.
Impact factor:
Publication type: Paper in international publication
Authors: Arrue, Mercedes; Buxo, Xavier; Cacho Lavin, Diego; Cano, Juana Maria; Carmona-Bayonas, Alberto; Cerda, Paula; Cruz, Maria-Jesus; Custodio, Ana; de Homdedeu, Miquel; Delgado, Pilar et al.
DOI: 10.1177/0271678X231214826

Neonatal and Infant Lung Disorders: Glossary, Practical Approach, and Diagnoses.

PMID: 37982525
Journal: JOURNAL OF THORACIC IMAGING
Year: 2023
Reference: J Thorac Imaging. 2023 Nov 3. doi: 10.1097/RTI.0000000000000758.
Impact factor:
Publication type: Paper in international publication
Authors: Arrue, Mercedes; Buxo, Xavier; Chu, Winnie C; Concepcion, Nathan David P; Cruz, Maria-Jesus; Daltro, Pedro; de Homdedeu, Miquel; Delgado, Pilar; DiPrete, Olivia; Elicegui, Amaia et al.
DOI: 10.1097/RTI.0000000000000758

Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke.

PMID: 35226340
Journal: Neurotherapeutics
Year: 2022
Reference: Neurotherapeutics. 2022 Mar;19(2):513-527. doi: 10.1007/s13311-022-01203-0. Epub 2022 Feb 28.
Impact factor:
Publication type: Paper in international publication
Authors: Artigas, Laura; de Ramon, Helena; Garcia-Rodriguez, Paula; Montaner, Joan; Orset, Cyrille; Ramiro, Laura; Rosell, Anna; Sardon, Teresa; Simats, Alba; Valls, Raquel et al.
DOI: 10.1007/s13311-022-01203-0

Biological Age Acceleration Is Lower in Women With Ischemic Stroke Compared to Men.

PMID: 35209739
Journal: STROKE
Year: 2022
Reference: Stroke. 2022 Jul;53(7):2320-2330. doi: 10.1161/STROKEAHA.121.037419. Epub 2022 Feb 25.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera-Simon, Ana; Camps-Renom, Pol; Carcel-Marquez, Jara; Cullell, Natalia; Delgado, Pilar; Delgado-Mederos, Raquel; Fernandez-Cadenas, Israel; Gallego-Fabrega, Cristina; Jimenez-Conde, J; Krupinski, Jerzy et al.
DOI: 10.1161/STROKEAHA.121.037419

Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke.

PMID: 35213696
Journal: BRAIN
Year: 2022
Reference: Brain. 2022 Jul 29;145(7):2394-2406. doi: 10.1093/brain/awac080.
Impact factor:
Publication type: Paper in international publication
Authors: Amini, Hajar; Ander, Bradley P; Arauz, Antonio; Arenillas, Juan Francisco; Arias-Rivas, Susana; Bang, Oh Young; Barboza, Miguel A; Bergmann, Kristy; Bradley, Joseph; Budde, John et al.
DOI: 10.1093/brain/awac080

Mortality and bleeding complications of COVID-19 critically ill patients with venous thromboembolism.

PMID: 34751541
Journal: INTERNATIONAL ANGIOLOGY
Year: 2022
Reference: Int Angiol. 2022 Feb;41(1):1-8. doi: 10.23736/S0392-9590.21.04704-0. Epub 2021 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Bellmunt, Sergi; DE Nadal, Miriam; Ferrer, Ricard; Garcia-Reyes, Marvin; Gil, Miquel; Gil-Sala, Daniel; Llagostera, Secundino; Marrero, Carlos E; Martinez, Lucia; Riera, Claudia et al.
DOI: 10.23736/S0392-9590.21.04704-0

SSAO/VAP-1 in Cerebrovascular Disorders: A Potential Therapeutic Target for Stroke and Alzheimer's Disease.

PMID: 33805974
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Mar 25;22(7). pii: ijms22073365. doi: 10.3390/ijms22073365.
Impact factor:
Publication type: Review in international publication
Authors: Hernandez-Guillamon, Mar; Sole, Montse; Sun, Ping; Unzeta, Mercedes et al.
DOI: 10.3390/ijms22073365

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

PMID: 33773637
Journal: LANCET NEUROLOGY
Year: 2021
Reference: Lancet Neurol. 2021 May;20(5):351-361. doi: 10.1016/S1474-4422(21)00031-4. Epub 2021 Mar 25.
Impact factor:
Publication type: Paper in international publication
Authors: Abedi, Vida; Anderson, Christopher D; Bakker, Mark K; Bell, Steven; Crawford, Katherine; Dichgans, Martin; Fernandez-Cadenas, Israel; Grewal, Raji P; Griessenauer, Christoph J; Havulinna, Aki et al.
DOI: 10.1016/S1474-4422(21)00031-4

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction.

PMID: 33778207
Journal: Bioactive Materials
Year: 2021
Reference: Bioact Mater. 2021 Mar 15;6(10):3314-3327. doi: 10.1016/j.bioactmat.2021.02.026. eCollection 2021 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Bayes-Genis, Antoni; Borras, Francesc E; Calle, Alexandra; Clos-Sansalvador, Marta; Cserkoova, Adriana; Galvez-Monton, Carolina; Gastelurrutia, Paloma; Monguio-Tortajada, Marta; Morancho, Anna; Moron-Font, Miriam et al.
DOI: 10.1016/j.bioactmat.2021.02.026

Genome-wide transcriptome study in skin biopsies reveals an association of E2F4 with cadasil and cognitive impairment.

PMID: 33767277
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Mar 25;11(1):6846. doi: 10.1038/s41598-021-86349-1.
Impact factor:
Publication type: Paper in international publication
Authors: Carcel-Marquez, Jara; Carrera, Caty; Cullell, Natalia; Espejo, Eva; Fernandez-Cadenas, Israel; Gallego-Fabrega, Cristina; Gonzalez-Sanchez, Jonathan; Jimenez-Balado, Joan; Krupinski, Jurek; Lledos, Miquel et al.
DOI: 10.1038/s41598-021-86349-1

Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis.

PMID: 32518978
Journal: JOURNAL OF NEUROLOGY
Year: 2020
Reference: J Neurol. 2020 Oct;267(10):3021-3037. doi: 10.1007/s00415-020-09932-y. Epub 2020 Jun 9.
Impact factor:
Publication type: Review in international publication
Authors: Barber, Philip A; Bath, Philip M; Cox, Dermot; Dawson, Jesse; Fernandez-Cadenas, Israel; Ford, Gary A; Kelly, Peter J; Lim, Soon Tjin; Lim, Su-Yin; Marquardt, Lars et al.
DOI: 10.1007/s00415-020-09932-y

Ambulatory Blood Pressure Levels in the Prediction of Progression of Cerebral Small Vessel Disease.

PMID: 32511756
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2020
Reference: J Am Geriatr Soc. 2020 Oct;68(10):2232-2239. doi: 10.1111/jgs.16568. Epub 2020 Jun 8.
Impact factor:
Publication type: Paper in international publication
Authors: Delgado, Pilar; Jimenez-Balado, Joan; Maisterra, Olga; Mundet, Xavier; Palasi, Antoni; Pizarro, Jesus; Pujadas, Francesc; Riba-Llena, Iolanda; Vinyoles, Ernest et al.
DOI: 10.1111/jgs.16568

Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC).

PMID: 32472697
Journal: CLINICAL PHARMACOLOGY & THERAPEUTICS
Year: 2020
Reference: Clin Pharmacol Ther. 2020 Nov;108(5):1067-1077. doi: 10.1002/cpt.1911. Epub 2020 Jul 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alexopoulos, Dimitrios; Altman, Russ B; Aradi, Daniel; Backman, Joshua D; Bergmeijer, Thomas O; Bliden, Kevin; Bradford, Yuki; Campo, Gianluca; Chang, Kiyuk; Cleator, John H et al.
DOI: 10.1002/cpt.1911

Break in the Stroke Chain of Survival Due to COVID-19.

PMID: 32466738
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Aug;51(8):2307-2314. doi: 10.1161/STROKEAHA.120.030106. Epub 2020 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Barragan-Prieto, Ana; Escudero-Martinez, Irene; Gonzalez, Alejandro; Moniche, Francisco; Montaner, Joan; Perez-Sanchez, Soledad; Ruiz-Bayo, Lidia; Sanchez-Miura, Jose Antonio et al.
DOI: 10.1161/STROKEAHA.120.030106

Biomarkers of immune capacity, infection and inflammation are associated with poor outcome and mortality after stroke - the PREDICT study.

PMID: 31269910
Journal: BMC Neurology
Year: 2019
Reference: BMC Neurol. 2019 Jul 3;19(1):148. doi: 10.1186/s12883-019-1375-6.
Impact factor:
Publication type: Paper in international publication
Authors: Grittner, U; Harms, H; Hoffmann, S; Hotter, B; Meisel, A; Meisel, C; Mengel, A; Montaner, J; Piper, S K; Ulm, L et al.
DOI: 10.1186/s12883-019-1375-6

Comments on: "Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage".

PMID: 31256985
Journal: Journal of Stroke & Cerebrovascular Diseases
Year: 2019
Reference: J Stroke Cerebrovasc Dis. 2019 Sep;28(9):2585-2586. doi: 10.1016/j.jstrokecerebrovasdis.2019.06.014. Epub 2019 Jun 28.
Impact factor:
Publication type: Letter or abstract
Authors: Bustamante, Alejandro; Gill-Testa, Natalia; Montaner, Joan; Penalba, Anna; Ramiro, Laura; Simats, Alba et al.
DOI: 10.1016/j.jstrokecerebrovasdis.2019.06.014

Genetically Determined Risk of Depression and Functional Outcome After Ischemic Stroke.

PMID: 31238828
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Aug;50(8):2219-2222. doi: 10.1161/STROKEAHA.119.026089. Epub 2019 Jun 26.
Impact factor:
Publication type: Paper in international publication
Authors: Fernandez-Cadenas, Israel; Gill, Dipender; Hankey, Graeme J; James, Nicole E; Jern, Christina; Lemmens, Robin; Lindgren, Arne; Lorentzen, Erik; Maguire, Jane M; Monori, Grace et al.
DOI: 10.1161/STROKEAHA.119.026089

Early efficacy and late gain in chronic and high-frequency episodic migraine with OnabotulinumtoxinA.

PMID: 31220392
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2019
Reference: Eur J Neurol. 2019 Dec;26(12):1464-1470. doi: 10.1111/ene.14028. Epub 2019 Jul 18.
Impact factor:
Publication type: Paper in international publication
Authors: Alpuente, Alicia; Alvarez-Sabin, Jose; Gallardo, Victor Jose; Pozo-Rosich, Patricia; Torres-Ferrus, Marta et al.
DOI: 10.1111/ene.14028

Characterization of the rat cerebrospinal fluid proteome following acute cerebral ischemia using an aptamer-based proteomic technology.

PMID: 29784938
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 May 21;8(1):7899. doi: 10.1038/s41598-018-26237-3.
Impact factor:
Publication type: Paper in international publication
Authors: Bustamante, Alejandro; Garcia-Berrocoso, Teresa; Gill, Natalia; Giralt, Dolors; Montaner, Joan; Penalba, Anna; Ramiro, Laura; Rosell, Anna; Simats, Alba et al.
DOI: 10.1038/s41598-018-26237-3

Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium.

PMID: 29781122
Journal: STEM CELLS
Year: 2018
Reference: Stem Cells. 2018 Sep;36(9):1404-1410. doi: 10.1002/stem.2856. Epub 2018 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Arai, Ken; Bruzzese, Morgan; Chan, Su Jing; Hayakawa, Kazuhide; Lo, Eng H; Mandeville, Emiri T; Montaner, Joan; Park, Ji Hyun; Rosell, Anna et al.
DOI: 10.1002/stem.2856

Intravenous lacosamide (LCM) in status epilepticus (SE): Weight-adjusted dose and efficacy.

PMID: 29758445
Journal: EPILEPSY & BEHAVIOR
Year: 2018
Reference: Epilepsy Behav. 2018 Jul;84:93-98. doi: 10.1016/j.yebeh.2018.04.025. Epub 2018 May 11.
Impact factor:
Publication type: Paper in international publication
Authors: Becerra, Juan Luis; Fernandez, Angel; Gonzalez-Cuevas, Montserrat; Jimenez, Marta; Marinas, Ainhoa; Mauri, J A; Puig, Xavier Salas; Quilez, Alex; Quintana, Manuel; Santamarina, Estevo et al.
DOI: 10.1016/j.yebeh.2018.04.025

Arterial Stiffness Is Associated With Basal Ganglia Enlarged Perivascular Spaces and Cerebral Small Vessel Disease Load.

PMID: 29669870
Journal: STROKE
Year: 2018
Reference: Stroke. 2018 May;49(5):1279-1281. doi: 10.1161/STROKEAHA.118.020163. Epub 2018 Apr 18.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Castane, Xavier; Delgado, Pilar; Girona, Anna; Jarca, Carmen I; Jimenez-Balado, Joan; Lopez-Rueda, Antonio; Montaner, Joan; Mundet, Xavier; Riba-Llena, Iolanda et al.
DOI: 10.1161/STROKEAHA.118.020163

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).

PMID: 28797196
Journal: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Year: 2017
Reference: J Cereb Blood Flow Metab. 2017 Nov;37(11):3488-3517. doi: 10.1177/0271678X17709185. Epub 2017 Aug 11.
Impact factor:
Publication type: Clinical guide
Authors: Alfieri, Alessio; Allan, Stuart M; Carswell, Hilary Vo; Deuchar, Graeme A; Farr, Tracy D; Flecknell, Paul; Gallagher, Lindsay; Gibson, Claire L; Haley, Michael J; Macleod, Malcolm R et al.
DOI: 10.1177/0271678X17709185

The choroid plexus is a key cerebral invasion route for T cells after stroke.

PMID: 28762187
Journal: ACTA NEUROPATHOLOGICA
Year: 2017
Reference: Acta Neuropathol. 2017 Dec;134(6):851-868. doi: 10.1007/s00401-017-1758-y. Epub 2017 Jul 31.
Impact factor:
Publication type: Paper in international publication
Authors: Arzberger, Thomas; Benakis, Corinne; Cai, Ruiyao; Engelhardt, Britta; Enzmann, Gaby; Erturk, Ali; Ghasemigharagoz, Alireza; Haffner, Christof; Lazarevic, Ivana; Liebscher, Sabine et al.
DOI: 10.1007/s00401-017-1758-y

Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: A meta-analysis.

PMID: 28747441
Journal: NEUROLOGY
Year: 2017
Reference: Neurology. 2017 Aug 22;89(8):820-829. doi: 10.1212/WNL.0000000000004259. Epub 2017 Jul 26.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Shahi Salman, Rustam; Baron, Jean-Claude; Biffi, Alexandro; Casolla, Barbara; Charidimou, Andreas; Cordonnier, Charlotte; Greenberg, Steven M; Gregoire, Simone M; Hernandez-Guillamon, Mar; Imaizumi, Toshio et al.
DOI: 10.1212/WNL.0000000000004259

Quinolinyl nitrone RP19 induces neuroprotection after transient brain ischemia.

PMID: 28731692
Journal: ACS Chemical Neuroscience
Year: 2017
Reference: ACS Chem Neurosci. 2017 Oct 18;8(10):2202-2213. doi: 10.1021/acschemneuro.7b00126. Epub 2017 Aug 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alcazar, Alberto; Ayuso, Maria Irene; Chioua, Mourad; Escobar-Peso, Alejandro; Gonzalo-Gobernado, Rafael; Marco-Contelles, Jose; Martinez-Alonso, Emma; Montaner, Joan et al.
DOI: 10.1021/acschemneuro.7b00126

Combination of Thrombolysis and Statins in Acute Stroke Is Safe: Results of the STARS Randomized Trial (Stroke Treatment With Acute Reperfusion and Simvastatin).

PMID: 27758944
Journal: STROKE
Year: 2016
Reference: Stroke. 2016 Nov;47(11):2870-2873. doi: 10.1161/STROKEAHA.116.014600. Epub 2016 Oct 6.
Impact factor:
Publication type: Clinical Trials
Authors: Bravo, Yolanda; Bustamante, Alejandro; Canovas, David; Corbeto, Natalia; de Arce, Anna; de la Torre, Javier; Delgado, Pilar; Delgado-Mederos, Raquel; Freijo, Mar; Garcia-Matas, Silvia et al.
DOI: 10.1161/STROKEAHA.116.014600

Automated quantification of cerebral edema following hemispheric infarction: Application of a machine-learning algorithm to evaluate CSF shifts on serial head CTs.

PMID: 27761398
Journal: NeuroImage-Clinical
Year: 2016
Reference: Neuroimage Clin. 2016 Sep 26;12:673-680. eCollection 2016.
Impact factor:
Publication type: Paper in international publication
Authors: An, Hongyu; Carrera, Caty; Chen, Yasheng; Dhar, Rajat; Fernandez-Cadenas, Israel; Ford, Andria; Heitsch, Laura; Lee, Jin-Moo; Lin, Weili; Montaner, Joan et al.
DOI: 10.1016/j.nicl.2016.09.018

Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.

PMID: 27604134
Journal: THROMBOSIS AND HAEMOSTASIS
Year: 2016
Reference: Thromb Haemost. 2016 Nov 30;116(6):1165-1171. doi: 10.1160/TH16-02-0113. Epub 2016 Sep 8.
Impact factor:
Publication type: Paper in international publication
Authors: Beltran, Sergi; Carrera, Caty; Cruchaga, Carlos; Delgado, Pilar; Derdak, Sophia; Diaz-Navarro, Rosa M; Fernandez-Cadenas, Israel; Gallego-Fabrega, Cristina; Giralt-Steinhauer, Eva; Jimenez-Conde, Jordi et al.
DOI: 10.1160/TH16-02-0113

Hyperfibrinolysis increases blood brain barrier permeability by a plasmin and bradykinin-dependent mechanism.

PMID: 27531677
Journal: BLOOD
Year: 2016
Reference: Blood. 2016 Nov 17;128(20):2423-2434. doi: 10.1182/blood-2016-03-705384. Epub 2016 Aug 16.
Impact factor:
Publication type: Paper in international publication
Authors: Anfray, Antoine; Bardou, Isabelle; Frigout, Yvann; Gauberti, Maxime; Hommet, Yannick; Lebouvier, Laurent; Marcos-Contreras, Oscar A; Martinez de Lizarrondo, Sara; Montaner, Joan; Orset, Cyrille et al.
DOI: 10.1182/blood-2016-03-705384

Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.

PMID: 25653287
Journal: NEUROLOGY
Year: 2015
Reference: Neurology. 2015 Mar 3;84(9):918-26. doi: 10.1212/WNL.0000000000001309. Epub 2015 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Anderson, Christopher D; Attia, John; Battey, Thomas W K; Bevan, Steve; Bis, Joshua C; Boncoraglio, Giorgio B; Brown, Devin L; Davies, Gail; Debette, Stephanie; Deka, Ranjan et al.
DOI: 10.1212/WNL.0000000000001309

Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicity.

PMID: 26492372
Journal: CELL DEATH DIS
Year: 2015
Reference: Cell Death Dis. 2015 Oct 22;6:e1939. doi: 10.1038/cddis.2015.307.
Impact factor:
Publication type: Paper in international publication
Authors: Ayuso-Dolado, S; Diaz-Guerra, M; Gamir-Morralla, A; Iglesias, T; Lopez-Menendez, C; Montaner, J; Rosell, A; Tejeda, G S et al.
DOI: 10.1038/cddis.2015.307

CholesteroNitrones for Stroke.

PMID: 26241908
Journal: J MED CHEM
Year: 2015
Reference: J Med Chem. 2015 Aug 27;58(16):6704-9. doi: 10.1021/acs.jmedchem.5b00755. Epub 2015 Aug 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alcazar, Alberto; Ayuso, Maria I; Chioua, Mourad; Hadjipavlou-Litina, Dimitra J; Marco-Contelles, Jose; Martinez-Alonso, Emma; Masjuan, Jaime; Montaner, Joan; Soriano, Elena et al.
DOI: 10.1021/acs.jmedchem.5b00755

DNA methylation levels are highly correlated between pooled samples and averaged values when analysed using the Infinium HumanMethylation450 BeadChip array.

PMID: 26236407
Journal: CLIN EPIGENETICS
Year: 2015
Reference: Clin Epigenetics. 2015 Jul 31;7(1):78. doi: 10.1186/s13148-015-0097-x. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Carrera, Caty; Fernandez-Cadenas, Israel; Gallego-Fabrega, Cristina; Krupinski, Jurek; Montaner, Joan; Muino, Elena et al.
DOI: 10.1186/s13148-015-0097-x

Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply.

PMID: 24849857
Journal: LANCET NEUROLOGY
Year: 2014
Reference: Lancet Neurol. 2014 Jun;13(6):540. doi: 10.1016/S1474-4422(14)70097-3.
Impact factor:
Publication type: Letter whit IF
Authors: Al-Shahi Salman, Rustam; Biessels, Geert Jan; Cordonnier, Charlotte; Greenberg, Steven M; Lee, Jin-Moo; Montaner, Joan; Schneider, Julie A; Smith, Eric E; van Buchem, Mark; Vernooij, Meike et al.
DOI: 10.1016/S1474-4422(14)70097-3

EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke.

PMID: 24828363
Journal: International Journal of Stroke
Year: 2014
Reference: Int J Stroke. 2014 Jul;9(5):642-5. doi: 10.1111/ijs.12294. Epub 2014 May 15.
Impact factor:
Publication type: Clinical Trials
Authors: Bath, P M W; Bath, Philip M W; Brainin, M; Broessner, G; Colam, B; Cordonnier, C; Czlonkowska, A; Dalkara, T; Demotes, J; Demotes, Jacques et al.
DOI: 10.1111/ijs.12294

Global DNA methylation of ischemic stroke subtypes.

PMID: 24788121
Journal: PLoS One
Year: 2014
Reference: PLoS One. 2014 Apr 30;9(4):e96543. doi: 10.1371/journal.pone.0096543. eCollection 2014.
Impact factor:
Publication type: Paper in international publication
Authors: Carrera, Caty; Cuadrado-Godia, Elisa; Elosua, Roberto; Fernandez-Cadenas, Israel; Giralt-Steinhauer, Eva; Jimenez-Conde, Jordi; Mola, Marina; Montaner, Joan; Ois, Angel; Rodriguez-Campello, Ana et al.
DOI: 10.1371/journal.pone.0096543

How to unfasten the Spanish Stroke Belt? Andalusia chooses research.

PMID: 25042753
Journal: International Journal of Stroke
Year: 2014
Reference: Int J Stroke. 2014 Oct;9(7):946-9. doi: 10.1111/ijs.12332. Epub 2014 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Jimenez-Hernandez, M D; Lopez-Barneo, J; Montaner, J et al.
DOI: 10.1111/ijs.12332

Genes involved in hemorrhagic transformations that follow recombinant t-PA treatment in stroke patients.

PMID: 23556447
Journal: PHARMACOGENOMICS
Year: 2013
Reference: Pharmacogenomics. 2013 Apr;14(5):495-504. doi: 10.2217/pgs.13.19.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Chacon, Pilar; Delgado, Pilar; Domingues-Montanari, Sophie; Fernandez-Cadenas, Israel; Fernandez-Morales, Jessica; Garcia-Arumi, Elena; Hernandez-Guillamon, Mar; Mendioroz, Maite; Molina, Carlos A et al.
DOI: 10.2217/pgs.13.19

Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice.

PMID: 24023842
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Sep 4;8(9):e73244. doi: 10.1371/journal.pone.0073244.
Impact factor:
Publication type: Paper in international publication
Authors: Barcelo, Veronica; Borras, Francesc; Garcia-Bonilla, Lidia; Hernandez-Guillamon, Mar; Lope-Piedrafita, Silvia; Martinez-Saez, Elena; Montaner, Joan; Morancho, Anna; Navarro-Sobrino, Miriam; Penalba, Anna et al.
DOI: 10.1371/journal.pone.0073244

Statin therapy should not be discontinued in patients with intracerebral hemorrhage.

PMID: 23765946
Journal: STROKE
Year: 2013
Reference: Stroke. 2013 Jul;44(7):2060-1. doi: 10.1161/STROKEAHA.113.000916. Epub 2013 Jun 13.
Impact factor:
Publication type: Paper in international publication
Authors: Bustamante, Alejandro; Montaner, Joan et al.
DOI: 10.1161/STROKEAHA.113.000916

Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage.

PMID: 23559261
Journal: STROKE
Year: 2013
Reference: Stroke. 2013 Jun;44(6):1578-83. doi: 10.1161/STROKEAHA.111.000089. Epub 2013 Apr 4.
Impact factor:
Publication type: Paper in international publication
Authors: Anderson, Christopher D; Ayres, Alison M; Biffi, Alessandro; Brown, Devin L; Cuadrado-Godia, Elisa; Delgado, Pilar; Devan, William J; Falcone, Guido J; Fernandez-Cadenas, Israel; Freudenberger, Paul et al.
DOI: 10.1161/STROKEAHA.111.000089

Biomarker level improves the diagnosis of embolic source in ischemic stroke of unknown origin.

PMID: 22592287
Journal: JOURNAL OF NEUROLOGY
Year: 2012
Reference: J Neurol. 2012 Dec;259(12):2538-45. doi: 10.1007/s00415-012-6532-4. Epub 2012 May 17.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1007/s00415-012-6532-4

Evidence for the efficacy of statins in animal stroke models: a meta-analysis.

PMID: 22548274
Journal: JOURNAL OF NEUROCHEMISTRY
Year: 2012
Reference: J Neurochem. 2012 Jul;122(2):233-43. doi: 10.1111/j.1471-4159.2012.07773.x. Epub 2012 May 21.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1471-4159.2012.07773.x

Vorapaxar in the secondary prevention of atherothrombotic events.

PMID: 22443427
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2012
Reference: N Engl J Med. 2012 Apr 12;366(15):1404-13. Epub 2012 Mar 24.
Impact factor:
Publication type: Paper in international publication
Authors: Abadier, R; Abell, T; Abrahams, L; Abramovich, M; Abramson, B; Abrantes, J A M; Accini, J L; Accini, M; Acevedo, L; Adachi, T et al.
DOI: 10.1056/NEJMoa1200933

Role of the MMP9 Gene in Hemorrhagic Transformations After Tissue-Type Plasminogen Activator Treatment in Stroke Patients.

PMID: 22496335
Journal: STROKE
Year: 2012
Reference: Stroke. 2012 May;43(5):1398-400. doi: 10.1161/STROKEAHA.111.639823. Epub 2012 Apr 10.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1161/STROKEAHA.111.639823

Effects of an omega-3 fatty acid-enriched lipid emulsion on eicosanoid synthesis in acute respiratory distress syndrome (ARDS): A prospective, randomized, double-blind, parallel group study.

PMID: 21477318
Journal: Nutrition & Metabolism
Year: 2011
Reference: Nutr Metab (Lond). 2011 Apr 8;8(1):22. doi: 10.1186/1743-7075-8-22.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; Joan Sabater et al.
DOI: 10.1186/1743-7075-8-22

ACE variants and risk of intracerebral hemorrhage recurrence in amyloid angiopathy.

PMID: 20381197
Journal: NEUROBIOLOGY OF AGING
Year: 2011
Reference: Neurobiol Aging. 2011 Mar;32(3):551.e13-22. Epub 2010 Apr 9.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.neurobiolaging.2010.01.019

Citicoline in Vascular Cognitive Impairment and Vascular Dementia After Stroke.

PMID: 21164117
Journal: STROKE
Year: 2011
Reference: Stroke. 2011 Jan;42(1 Suppl):S40-3. Epub 2010 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: ; et al.
DOI: 10.1161/STROKEAHA.110.606509

Effects of acute post-treatment with dipyridamole in a rat model of focal cerebral ischemia.

PMID: 21146508
Journal: BRAIN RESEARCH
Year: 2011
Reference: Brain Res. 2011 Feb 10;1373:211-20. Epub 2010 Dec 10.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.brainres.2010.12.005

The I/D polymorphism of the ACE1 gene is not associated with ischaemic stroke in Spanish individuals.

PMID: 20402757
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2010
Reference: Eur J Neurol. 2010 Nov;17(11):1390-2.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1468-1331.2010.03022.x

Stroke with polyvascular atherothrombotic disease.

PMID: 19695570
Journal: ATHEROSCLEROSIS
Year: 2010
Reference: Atherosclerosis. 2010 Feb;208(2):587-92. Epub 2009 Jul 28.
Impact factor:
Publication type: Paper in international publication
Authors: Aguera, Eduardo; Alvarez, Maria; Arboix, Adria; Arboix, Adria; Arce, Ana; Arribas, Maria Antonia; Asensi, Jose Maria; Bescansa, Enrique; Blanco, Miguel; Blanco, Miguel et al.
DOI: 10.1016/j.atherosclerosis.2009.07.041

PAI-1 4G/5G polymorphism is associated with brain vessel reocclusion after successful fibrinolytic therapy in ischemic stroke patients.

PMID: 20374070
Journal: INTERNATIONAL JOURNAL OF NEUROSCIENCE
Year: 2010
Reference: Int J Neurosci. 2010 Apr;120(4):245-51.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, J; Cuadrado, E; Del Rio-Espinola, A; Domingues-Montanari, S; Fernandez-Cadenas, I; Hernandez-Guillamon, M; Mendioroz, M; Molina, C A; Montaner, J; Ribo, M et al.
DOI: 10.3109/00207451003597169

Association of a Genetic Variant in the ALOX5AP with Higher Risk of Ischemic Stroke: A Case-Control, Meta-Analysis and Functional Study.

PMID: 20357438
Journal: CEREBROVASCULAR DISEASES
Year: 2010
Reference: Cerebrovasc Dis. 2010;29(6):528-37. doi: 10.1159/000302738. Epub 2010 Mar 30.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1159/000302738

Buying time for recanalization in acute stroke: arterial blood infusion beyond the occluding clot as a neuroprotective strategy.

PMID: 18800999
Journal: JOURNAL OF NEUROIMAGING
Year: 2009
Reference: J Neuroimaging. 2009 Apr;19(2):188-90.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Beatriz; Alvarez-Sabin, Jose; Dinia, Lavinia; Matas, Manel; Molina, Carlos; Ribo, Marc et al.
DOI: 10.1111/j.1552-6569.2008.00253.x

Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact.

PMID: 19574439
Journal: BRAIN
Year: 2009
Reference: Brain. 2009 Aug;132(Pt 8):2219-30.
Impact factor:
Publication type: Paper in international publication
Authors: Agin, Veronique; Ali, Carine; Castel, Herve; Dauphinot, Luce; Hommet, Yannick; Jullienne, Amandine; Macrez, Richard; Maubert, Eric; Montaner, Joan; Munuera, Josep et al.
DOI: 10.1093/brain/awp162

Invited Article: Searching for oracles? Blood biomarkers in acute stroke.

PMID: 19652144
Journal: NEUROLOGY
Year: 2009
Reference: Neurology. 2009 Aug 4;73(5):393-9.
Impact factor:
Publication type: Paper in international publication
Authors: Foerch, C; Furie, K L; Lo, E H; Montaner, J; Ning, M M et al.
DOI: 10.1212/WNL.0b013e3181b05ef9

Changes in lipid profile between flare and remission of patients with systemic lupus erythematosus: a prospective study.

PMID: 19531751
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2009
Reference: J Rheumatol. 2009 Aug;36(8):1639-45.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Chacon, Pilar; Ordi-Ros, Josep; Perez, Eduardo Hermosilla; Urquizu-Padilla, Maria; Vilardell-Tarres, Miquel et al.
DOI: 10.3899/jrheum.081097

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