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Neurovascular Diseases

Stroke is a medical emergency and a leading cause of death and disability worldwide affecting millions of subjects. In this context the Neurovascular Research Laboratory was created in 2001 focused in stroke research from a basic and translational perspective, covering all stages of the disease: from prevention and treatment, to recovery.

Nowadays our team is composed by a highly motivated group of researchers including clinical and basic scientists, with group leaders involved in National and International projects with public or private research funding on biomarkers for clinical decision making in stroke, the presence of silent infarctions, the assessment of cognition and cognitive decline, developing experimental models of cerebral ischemia testing new treatments complementary to reperfusion, and developing studies on cerebral amyloid angiopathy, tissue neurorepair or post-stroke rehabilitation.

Complementary studies on vascular dementia and Alzheimer disease related to amyloid-beta protein have also been encompassed as part of our research in the last years.

Publications

Bridging May Increase the Risk of Symptomatic Intracranial Hemorrhage in Thrombectomy Patients With Low Alberta Stroke Program Early Computed Tomography Score.

PMID: 33504188
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 Mar;52(3):1098-1104. doi: 10.1161/STROKEAHA.120.030508. Epub 2021 Jan 28.
Impact factor: 7.914
Publication type: Paper in international publication
Authors: Schaafsma, Joanna, Gawlitza, Matthias, Friedrich, Benjamin, Benali, Amel, Hajdu, Steven D, Requena, Manuel, Kaesmacher, Johannes, Meinel, Thomas R, Nannoni, Stefania, Olive-Gadea, Marta et al.
DOI: 10.1161/STROKEAHA.120.030508

Response by Olive Gadea and Ribo to Letter Regarding Article, "Deep Learning Based Software to Identify Large Vessel Occlusion on Noncontrast Computed Tomography".

PMID: 33493060
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 Jan;52(2):e63. doi: 10.1161/STROKEAHA.120.033116. Epub 2021 Jan 25.
Impact factor: 7.914
Publication type: Letter or abstract
Authors: Olive Gadea, Marta, Ribo, Marc et al.
DOI: 10.1161/STROKEAHA.120.033116

Angiotensin II-induced cardiomyocyte hypertrophy: A complex response dependent on intertwined pathways.

PMID: 33478847
Journal: Revista Portuguesa de Cardiologia
Year: 2021
Reference: Rev Port Cardiol. 2021 Mar;40(3):201-203. doi: 10.1016/j.repc.2020.12.009. Epub 2021 Jan 18.
Impact factor: 1.374
Publication type: Letter or abstract
Authors: Consegal, Marta, Valls-Lacalle, Laura, Rodriguez-Sinovas, Antonio et al.
DOI: 10.1016/j.repc.2020.12.009

Levetiracetam as first-line monotherapy for Idiopathic Generalized Epilepsy in women.

PMID: 33452703
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2021
Reference: Acta Neurol Scand. 2021 Apr;143(4):407-412. doi: 10.1111/ane.13389. Epub 2021 Jan 15.
Impact factor: 3.209
Publication type: Paper in international publication
Authors: Salas-Puig, Javier, Quintana, Manuel, Campos, Daniel, Llaurado, Arnau, Raspall, Miquel, Fonseca, Elena, Abraira, Laura, Santamarina, Estevo, Toledo, Manuel, Ballve, Alejandro et al.
DOI: 10.1111/ane.13389

Efficacy, retention, and safety of brivaracetam in adult patients with genetic generalized epilepsy.

PMID: 31731108
Journal: EPILEPSY & BEHAVIOR
Year: 2020
Reference: Epilepsy Behav. 2020 Jan;102:106657. doi: 10.1016/j.yebeh.2019.106657. Epub 2019 Nov 12.
Impact factor: 2.508
Publication type: Paper in international publication
Authors: Quintana, Manuel, Abraira, Laura, Santamarina, Estevo, Salas-Puig, Xavier, Toledo, Manuel, Guzman, Lorena, Fonseca, Elena et al.
DOI: 10.1016/j.yebeh.2019.106657

Sudden Recanalization: A Game-Changing Factor in Endovascular Treatment of Large Vessel Occlusion Strokes.

PMID: 32078495
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Apr;51(4):1313-1316. doi: 10.1161/STROKEAHA.119.028787. Epub 2020 Feb 14.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Garcia-Tornel, Alvaro, Rubiera, Marta, Requena, Manuel, Muchada, Marian, Pagola, Jorge, Rodriguez-Luna, David, Deck, Matias, Juega, Jesus, Rodriguez-Villatoro, Noelia, Boned, Sandra et al.
DOI: 10.1161/STROKEAHA.119.028787

PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities.

PMID: 32057060
Journal: Nanoscale
Year: 2020
Reference: Nanoscale. 2020 Feb 27;12(8):4988-5002. doi: 10.1039/c9nr10620k.
Impact factor: 6.895
Publication type: Paper in international publication
Authors: Llop, Jordi, Zhang, Yajie, Garcia-Gabilondo, Miguel, Grayston, Alba, Feiner, Irene V J, Anton-Sales, Irene, Loiola, Rodrigo A, Garcia-Dorado, David, Gosselet, Fabien, Rosell, Anna et al.
DOI: 10.1039/c9nr10620k

Kidney function changes and their relation with the progression of cerebral small vessel disease and cognitive decline.

PMID: 31869590
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2020
Reference: J Neurol Sci. 2020 Feb 15;409:116635. doi: 10.1016/j.jns.2019.116635. Epub 2019 Dec 14.
Impact factor: 3.115
Publication type: Paper in international publication
Authors: Jimenez-Balado, Joan, Riba-Llena, Iolanda, Pizarro, Jesus, Palasi, Antoni, Penalba, Anna, Ramirez, Clara, Maisterra, Olga, Espinel, Eugenia, Ramos, Natalia, Pujadas, Francesc et al.
DOI: 10.1016/j.jns.2019.116635

Blog

News

For three days, the III Stroke Congress of the national RICORS-ICTUS network and a symposium focused on cerebral haemorrhage were held.

The TOUCH MSCA-COFUND doctoral training programme, led by UAB and focusing on the field of mental health, has opened its first call for applications, offering 13 doctoral positions.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.