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Ophtalmology

The clinical and basic research activity of the Ophthalmology Research Group is dedicated to finding new treatments for blindness through the development of new therapies for macular and retinal degenerative diseases, as well as for retinal vascular diseases (diabetic retinopathy and retinal vascular occlusions). Our group consists of core researchers and clinical researchers, so there is a clear clinical translation of the ongoing research in the research group.

We have a research program for the development of new therapeutic strategies based on:

  • Cell therapies
  • Formulations of ocular solutions (LUCIA PI18 and CELLUX EuroNanoMed/AC19)
  • Biological matrices
  • Gene therapy
  • Animal models
  • Retinal cell models based on stem cell-derived organoids.

In the clinical part, the research group bases its activity on clinical trials to develop new treatments for retinal diseases as well as on the ophthalmic involvement of systemic treatments, an example is the phase II trial to test mesenchymal cells (MSV) intravitreal in non-arteritic ischemic optic neuropathy (NAION), the RECOGNISED study or the PULSAR study with aflibercept.

Team

Eric Kirkegaard Biosca

Eric Kirkegaard Biosca

Research technician
Ophtalmology
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Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
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Sara Martin Nalda

Sara Martin Nalda

Ophtalmology
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Valero Dominguez, Daniel

Valero Dominguez, Daniel

Ophtalmology
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Albert Arnaiz

Albert Arnaiz

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Ares Borras, Barbara

Ares Borras, Barbara

Postdoctoral researcher
Ophtalmology
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Eric Kirkegaard Biosca

Eric Kirkegaard Biosca

Research technician
Ophtalmology
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Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
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Sara Martin Nalda

Sara Martin Nalda

Ophtalmology
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Valero Dominguez, Daniel

Valero Dominguez, Daniel

Ophtalmology
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Albert Arnaiz

Albert Arnaiz

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Ares Borras, Barbara

Ares Borras, Barbara

Postdoctoral researcher
Ophtalmology
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Research lines

Non-viral gene therapy with Pigment Epithelium-Derived Factor (PEDF) in the treatment of dry and wet forms of AMD

IP: -

Projects

Hemopexin: un nuevo factor patogénico en las complicaciones microvasculares de la diabetes.

IP: Cristina Hernández Pascual
Collaborators: Marina Lopez Martinez, Ana Boixadera Espax, Alejandra Planas Vilaseca, Patricia Bogdanov Baruj, Pilar Costa Forner
Funding agency: Instituto de Salud Carlos III
Funding: 139150
Reference: PI22/01670
Duration: 01/01/2023 - 31/12/2025

RETVISION: Del diagnóstico genético molecular a las terapias avanzadas para tratar las enfermedades degenerativas de la retina.

IP: José García Arumí
Collaborators: María Antolín Mate, Anna Duarri Piqué, Helena Isla Magrané, Claudia Garcia-Arumí Fusté, Miguel Angel Zapata Victori, Laura Natalia Distefano, Maddalen Zufiaurre Seijo
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI22/01747
Duration: 01/01/2023 - 31/12/2025

Microperimetry and serum biomarkers for identifying type 2 diabetic patients with cognitive impairment. A cross-sectional and prospective study.

IP: Olga Simó Servat
Collaborators: Ana Boixadera Espax, Marina Giralt Arnaiz, Cristina Udina Argilaga
Funding agency: Instituto de Salud Carlos III
Funding: 82280
Reference: PI20/01703
Duration: 01/01/2021 - 30/06/2025

Estudio de seguridad y eficacia de la sitagliptina en colirio para el tratamiento de los estadios iniciales de retinopatía diabética.

IP: Rafael Simó Canonge
Collaborators: Marc Rivas Agudo, Cristina Hernández Pascual, José García Arumí
Funding agency: Instituto de Salud Carlos III
Funding: 573650
Reference: ICI20/00129
Duration: 01/01/2021 - 31/10/2026

Publications

Chitinase 3-like 1 is neurotoxic in multiple sclerosis patient-derived cortical neurons.

PMID: 39658520
Journal: Clinical and Translational Medicine
Year: 2024
Reference: Clin Transl Med. 2024 Dec;14(12):e70125. doi: 10.1002/ctm2.70125.
Impact factor:
Publication type: Paper in international publication
Authors: Comabella, Manuel; Duarri, Anna; Eixarch, Herena; Lizcano, Jose M; Lopez Comellas, Gloria; Malhotra, Sunny; Matute-Blanch, Clara; Montalban, Xavier; Pinteac, Rucsanda; Soriano, Jordi et al.
DOI: 10.1002/ctm2.70125

Regulatory T cell expansion prevents retinal degeneration in type 2 diabetes.

PMID: 39716335
Journal: Journal of Neuroinflammation
Year: 2024
Reference: J Neuroinflammation. 2024 Dec 23;21(1):328. doi: 10.1186/s12974-024-03323-0.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Guaita, Anna; Bogdanov, Patricia; de la Fuente, Alerie G; Deas-Just, Anna; Duarri, Anna; Garcia-Ramirez, Marta; Gomez-Sanchez, Jose A; Hernandez, Cristina; Llorian-Salvador, Maria; Perez-Martinez, Daniel et al.
DOI: 10.1186/s12974-024-03323-0

Generation of three human induced pluripotent stem cell lines from retinitis pigmentosa 25 patient and two carriers but asymptomatic daughters.

PMID: 39742628
Journal: Stem Cell Research
Year: 2024
Reference: Stem Cell Res. 2024 Dec 28;82:103645. doi: 10.1016/j.scr.2024.103645.
Impact factor:
Publication type: Paper in international publication
Authors: Duarri, Anna; Garcia-Arumi, Josep; Isla-Magrane, Helena; Zapata, Miguel Angel; Zufiaurre-Seijo, Maddalen et al.
DOI: 10.1016/j.scr.2024.103645

Therapeutic Keratoplasty for Fusarium Keratitis.

PMID: 39768698
Journal: Journal of Clinical Medicine
Year: 2024
Reference: J Clin Med. 2024 Dec 19;13(24):7775. doi: 10.3390/jcm13247775.
Impact factor:
Publication type: Paper in international publication
Authors: Anglada-Masferrer, Natalia; Bisbe, Laia; Gutuleac, Liliana; Martin, Sara; Martin-Gomez, Maria Teresa; Oliver-Gutierrez, David; Puig, Javier Jose; Segura-Duch, Gloria; Zapata, Miguel Angel et al.
DOI: 10.3390/jcm13247775

Outcomes of switching from proactive to reactive treatment after developing advanced central neovascular age-related macular degeneration.

PMID: 36893432
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2023
Reference: Retina. 2023 Jul 1;43(7):1070-1080. doi: 10.1097/IAE.0000000000003771.
Impact factor:
Publication type: Paper in international publication
Authors: Barthelmes, Daniel; Cornish, Elisa E; Gemmy Cheung, Chui Ming; Gillies, Mark C; Guillaumie, Tremeur; Morros, Helena Brosa; Morros, Helena Brosa; Nguyen, Vuong; Oei, Sioe Lan; Puzo, Martin et al.
DOI: 10.1097/IAE.0000000000003771

Serum glial fibrillary acidic protein and neurofilament light chain as biomarkers of retinal neurodysfunction in early diabetic retinopathy: results of the EUROCONDOR study.

PMID: 36959506
Journal: ACTA DIABETOLOGICA
Year: 2023
Reference: Acta Diabetol. 2023 Jun;60(6):837-844. doi: 10.1007/s00592-023-02076-1. Epub 2023 Mar 23.
Impact factor:
Publication type: Paper in international publication
Authors: Cunha-Vaz, Jose; Frydkjaer-Olsen, Ulrik; Garcia-Arumi, Jose; Grauslund, Jakob; Harding, Simon P; Hernandez, Cristina; Hernandez, Cristina; Porta, Massimo; Ribeiro, Luisa; Scanlon, Peter et al.
DOI: 10.1007/s00592-023-02076-1

Delayed suprachoroidal hemorrhage after descemet stripping automated endothelial keratoplasty (DSAEK).

PMID: 37023849
Journal: Archivos de la Sociedad Espanola de Oftalmologia
Year: 2023
Reference: Arch Soc Esp Oftalmol (Engl Ed). 2023 Apr 4:S2173-5794(23)00044-0. doi: 10.1016/j.oftale.2023.04.001.
Impact factor:
Publication type: Letter or abstract
Authors: Bisbe, L; Buck, P; Buck, P; Martin Nalda, S; Oliver-Gutierrez, D; Oliver-Gutierrez, D; Ros-Sanchez, E; Ros-Sanchez, E; Segura-Duch, G et al.
DOI: 10.1016/j.oftale.2023.04.001

Hybrid neurofibroma/schwannoma of the orbit.

PMID: 37061243
Journal: Revista espanola de patologia
Year: 2023
Reference: Rev Esp Patol. 2023 Apr-Jun;56(2):140-143. doi: 10.1016/j.patol.2022.03.002. Epub 2022 Jun 15.
Impact factor:
Publication type: Letter or abstract
Authors: Arcediano, Miguel Angel; Arcediano, Miguel Angel; Dinares, Carme; Dinares, Carme; Naranjo, Lourdes; Ramon Y Cajal, Santiago; Ramon Y Cajal, Santiago; Romagosa, Cleofe; Romagosa, Cleofe; Salazar-Huayna, Lourdes et al.
DOI: 10.1016/j.patol.2022.03.002

A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population.

PMID: 35749108
Journal: Translational Vision Science & Technology
Year: 2022
Reference: Transl Vis Sci Technol. 2022 Jun 1;11(6):23. doi: 10.1167/tvst.11.6.23.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Luis; Aslam, Tariq M; de Dios Hernandez, Jose M; Garcia-Arumi, Jose; Garcia-Layana, Alfredo; Gea-Sanchez, Alfredo; Ibanez, Isabel Lopez; Lopez-Galvez, Maribel; Marin-Mendez, Juan J; Minnella, Angelo M et al.
DOI: 10.1167/tvst.11.6.23

Validation of an autonomous artificial intelligence-based diagnostic system for holistic maculopathy screening in a routine occupational health checkup context.

PMID: 35567610
Journal: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Year: 2022
Reference: Graefes Arch Clin Exp Ophthalmol. 2022 Oct;260(10):3255-3265. doi: 10.1007/s00417-022-05653-2. Epub 2022 May 14.
Impact factor:
Publication type: Paper in international publication
Authors: Bures, Anniken; Font, Octavi; Garcia, Sandra Banderas; Royo, Didac; Salinas, Cecilia; Torrents-Barrena, Jordina; Zapata, Miguel Angel; Zarranz-Ventura, Javier et al.
DOI: 10.1007/s00417-022-05653-2

Retinal microvascular abnormalities in patients after COVID-19 depending on disease severity.

PMID: 33328184
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2022
Reference: Br J Ophthalmol. 2022 Apr;106(4):559-563. doi: 10.1136/bjophthalmol-2020-317953. Epub 2020 Dec 16.
Impact factor:
Publication type: Paper in international publication
Authors: Arcos, Gabriel; Banderas Garcia, Sandra; Falco, Anna; Garcia-Arumi, Jose; Otero-Romero, Susana; Sanchez, Adrian; Velazquez-Villoria, Daniel; Zapata, Miguel Angel et al.
DOI: 10.1136/bjophthalmol-2020-317953

Orbital filariasis.

PMID: 35282899
Journal: MEDICINA CLINICA
Year: 2022
Reference: Med Clin (Barc). 2022 Jul 8;159(1):56. doi: 10.1016/j.medcli.2022.02.004. Epub 2022 Mar 10.
Impact factor:
Publication type: Paper in national publication
Authors: Garrido-Marin, Marta; Sanchez-Dalmau, Bernardo F; Sanchez-Vela, Laura et al.
DOI: 10.1016/j.medcli.2022.02.004

Ex-Press P50 device filtering failure due to non-visible intraluminal blockages.

PMID: 32838551
Journal: EUROPEAN JOURNAL OF OPHTHALMOLOGY
Year: 2021
Reference: Eur J Ophthalmol. 2021 Jul;31(4):1822-1828. doi: 10.1177/1120672120952032. Epub 2020 Aug 24.
Impact factor:
Publication type: Paper in international publication
Authors: Azarfane, Brahim; Banderas Garcia, Sandra; Castany Aregall, Marta; Dou Saenz De Vizmanos, Antonio; Garcia Arumi, Josep; Rigo Quera, Jaume et al.
DOI: 10.1177/1120672120952032

Interobserver and Intertest Agreement in Telemedicine Glaucoma Screening with Optic Disk Photos and Optical Coherence Tomography.

PMID: 34362120
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Jul 28;10(15). pii: jcm10153337. doi: 10.3390/jcm10153337.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Alfonso; Ayala-Fuentes, Miriam Eleonora; Castells, Xavier; Comas, Merce; Fatti, Gianluca; Herranz, Alejandra; Martinez-Prats, Elena; Monleon-Getino, Antoni; Morilla-Grasa, Antonio; Nolivos, Karen et al.
DOI: 10.3390/jcm10153337

Repopulation of decellularized retinas with hiPSC-derived retinal pigment epithelial and ocular progenitor cells shows cell engraftment, organization and differentiation.

PMID: 34332373
Journal: BIOMATERIALS
Year: 2021
Reference: Biomaterials. 2021 Sep;276:121049. doi: 10.1016/j.biomaterials.2021.121049. Epub 2021 Jul 24.
Impact factor:
Publication type: Paper in international publication
Authors: Duarri, Anna; Garcia-Arumi, Jose; Maqueda, Maria; Mosquera, Jose Luis; Veiga, Anna et al.
DOI: 10.1016/j.biomaterials.2021.121049

Fundus flavimaculatus-like in myotonic dystrophy: a case report.

PMID: 34051736
Journal: BMC Ophthalmology
Year: 2021
Reference: BMC Ophthalmol. 2021 May 29;21(1):240. doi: 10.1186/s12886-021-02002-5.
Impact factor:
Publication type: Letter or abstract
Authors: Azarfane, Brahim; Berges-Marti, Monica; Cilveti, Esther; Distefano, Laura; Garcia-Arumi, Jose; Kirkegaard-Biosca, Eric et al.
DOI: 10.1186/s12886-021-02002-5

Author Correction: The LRRC8-mediated volume-regulated anion channel is altered in glaucoma.

PMID: 32632252
Journal: Scientific Reports
Year: 2020
Reference: Sci Rep. 2020 Jul 7;10(1):11443. doi: 10.1038/s41598-020-68525-x.
Impact factor:
Publication type: Letter or abstract
Authors: Andres-Bilbe, Alba; Borras, Teresa; Canut, Maria Isabel; Castany, Marta; Castellanos, Aida; Comes, Nuria; Estevez, Raul; Gasull, Xavier; Rezola, Mikel et al.
DOI: 10.1038/s41598-020-68525-x

Is optical coherence tomography angiography helpful in the differential diagnosis of choroidal nevus versus melanoma?

PMID: 31210061
Journal: EUROPEAN JOURNAL OF OPHTHALMOLOGY
Year: 2020
Reference: Eur J Ophthalmol. 2020 Jul;30(4):723-729. doi: 10.1177/1120672119851768. Epub 2019 Jun 18.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Arumi Fuste, Claudia; Garcia-Arumi, Jose; Peralta Iturburu, Federico et al.
DOI: 10.1177/1120672119851768

Surgical Options for Optic Disc Pit Maculopathy: Perspectives and Controversies.

PMID: 32606575
Journal: Clinical ophthalmology (Auckland, N.Z.)
Year: 2020
Reference: Clin Ophthalmol. 2020 Jun 16;14:1601-1608. doi: 10.2147/OPTH.S250921. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Copete, Sergio; Garcia-Arumi Fuste, Claudia; Garcia-Arumi, Jose; Garcia-Onrubia, Luis; Pastor-Idoate, Salvador et al.
DOI: 10.2147/OPTH.S250921

EFFICACY AND SAFETY OF A TREAT-AND-EXTEND REGIMEN WITH AFLIBERCEPT IN TREATMENT-NAIVE PATIENTS WITH TYPE 3 NEOVASCULARIZATION: A 52-Week, Single-Arm, Multicenter Trial.

PMID: 31259813
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2020
Reference: Retina. 2020 Jul;40(7):1234-1244. doi: 10.1097/IAE.0000000000002582.
Impact factor:
Publication type: Paper in international publication
Authors: Arias, Luis; Cervera, Enrique; Escobar, Antonio Gomez; Escobar, Jose Juan; Vilimelis, Jaume Crespi; Zapata, Miguel Angel et al.
DOI: 10.1097/IAE.0000000000002582

Management of Wet Age-Related Macular Degeneration in Spain: Challenges for Treat and Extend Implementation in Routine Clinical Practice.

PMID: 31662900
Journal: Journal of Ophthalmology
Year: 2019
Reference: J Ophthalmol. 2019 Sep 30;2019:9821509. doi: 10.1155/2019/9821509. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Arias Barquet, L; Figueroa, M S; Garcia-Arumi, J; Garcia-Layana, A; Monclus-Arbona, L; Ruiz-Moreno, J M; The Spanish Amd Multicenter Group et al.
DOI: 10.1155/2019/9821509

Management of diabetic macular edema patients in clinical practice in Spain.

PMID: 30295076
Journal: EUROPEAN JOURNAL OF OPHTHALMOLOGY
Year: 2019
Reference: Eur J Ophthalmol. 2019 Nov;29(6):664-672. doi: 10.1177/1120672118804079. Epub 2018 Oct 7.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1177/1120672118804079

PREOPERATIVE VITREORETINAL INTERFACE ABNORMALITIES ON SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AS RISK FACTOR FOR PSEUDOPHAKIC CYSTOID MACULAR EDEMA AFTER PHACOEMULSIFICATION.

PMID: 30157113
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2019
Reference: Retina. 2019 Nov;39(11):2225-2232. doi: 10.1097/IAE.0000000000002298.
Impact factor:
Publication type: Paper in international publication
Authors: Copete, Sergio; Figueroa, Marta S; Garcia-Arumi, Jose; Marti-Rodrigo, Pablo; Muniz-Vidal, Romina; Pastor-Idoate, Salvador; Rigo, Jaume; Zapata, Miguel A et al.
DOI: 10.1097/IAE.0000000000002298

Disc-foveal angle and ocular counterrolling as a key in its interpretation.

PMID: 31582183
Journal: Archivos de la Sociedad Espanola de Oftalmologia
Year: 2019
Reference: Arch Soc Esp Oftalmol. 2019 Dec;94(12):585-590. doi: 10.1016/j.oftal.2019.05.019. Epub 2019 Oct 1.
Impact factor:
Publication type: Paper in national publication
Authors: Arcos Algaba, G; Galan Terraza, A; Garcia-Arumi, J; Lagreze, W A; Martin Begue, N; Mora Ramirez, D; Puig Galy, J; Velazquez Villoria, D; Velez Escola, L et al.
DOI: 10.1016/j.oftal.2019.05.019

Fibrin glue as agent for sealing corneal and conjunctival wound leaks.

PMID: 29075013
Journal: EYE
Year: 2018
Reference: Eye (Lond). 2018 Feb;32(2):463-466. doi: 10.1038/eye.2017.227. Epub 2017 Oct 27.
Impact factor: 2.478
Publication type: Paper in international publication
Authors: Scalcione, C, Ortiz-Vaquerizas, D, Said, D G, Dua, H S et al.
DOI: 10.1038/eye.2017.227

INTEROCULAR ASYMMETRY IN CHOROIDAL THICKNESS AND RETINAL SENSITIVITY IN HIGH MYOPIA.

PMID: 28682947
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2018
Reference: Retina. 2018 Aug;38(8):1620-1628. doi: 10.1097/IAE.0000000000001756.
Impact factor: 3.7
Publication type: Paper in international publication
Authors: Alzaben, Zeyad, Cardona, Genis, Zapata, Miguel A, Zaben, Ahmad et al.
DOI: 10.1097/IAE.0000000000001756

Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naive Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-Month, Single-Arm, Multicentre Trial.

PMID: 30405907
Journal: Journal of Ophthalmology
Year: 2018
Reference: J Ophthalmol. 2018 Oct 14;2018:8310350. doi: 10.1155/2018/8310350. eCollection 2018.
Impact factor: 1.68
Publication type: Paper in international publication
Authors: Manzanas, Lucia, Garcia-Arumi, Jose, Gomez-Ulla, Francisco, Amparo, Navea, Cervera, Enrique, Fonollosa, Alex, Arias, Luis, Araiz, Javier, Donate, Juan, de Figueroa, Marta Suarez et al.
DOI: 10.1155/2018/8310350

Keratitis secondary to Fusarium spp. in Spain 2012-2014.

PMID: 29150218
Journal: Archivos de la Sociedad Espanola de Oftalmologia
Year: 2018
Reference: Arch Soc Esp Oftalmol. 2018 Jun;93(6):283-289. doi: 10.1016/j.oftal.2017.08.005. Epub 2017 Nov 14.
Impact factor: 0
Publication type: Paper in national publication
Authors: Mosquera Gordillo, M A, Baron Cano, N, Garralda Luquin, A, Lopez Gutierrez, C, Mengual Verdu, E, Trujillo Cabrera, G, Garrido Fierro, J M, Lamarca Mateu, J, Sanchez Espana, J C, Marticorena Alvarez, P et al.
DOI: 10.1016/j.oftal.2017.08.005

Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy. Cross-sectional Analyses of Baseline Data of the EUROCONDOR project.

PMID: 28663190
Journal: DIABETES
Year: 2017
Reference: Diabetes. 2017 Sep;66(9):2503-2510. doi: 10.2337/db16-1453. Epub 2017 Jun 29.
Impact factor:
Publication type: Paper in international publication
Authors: Aldington Hnd, Stephen J; Bandello, Francesco; Costa, Miguel Angelo; Cunha-Vaz, Jose; Egan, Catherine; Frydkjaer-Olsen, Ulrik; Garcia-Arumi, Jose; Gibson, Jonathan; Grauslund DMSci, Jakob; Harding, Simon P et al.
DOI: 10.2337/db16-1453

Re: Martinez-Castillo et al.: Pars plana vitrectomy alone for the management of pseudophakic rhegmatogenous retinal detachment with only inferior breaks REPLY

PMID: 28528838
Journal: OPHTHALMOLOGY
Year: 2017
Reference: Ophthalmology. 2017 Jun;124(6):e52. doi: 10.1016/j.ophtha.2017.01.023.
Impact factor:
Publication type: Letter or abstract
Authors: Boixadera, Anna; Martinez-Castillo, Vicente J et al.
DOI: 10.1016/j.ophtha.2017.01.023

Guidelines for the Management of Diabetic Macular Edema by the European Society of Retina Specialists (EURETINA).

PMID: 28423385
Journal: OPHTHALMOLOGICA
Year: 2017
Reference: Ophthalmologica. 2017;237(4):185-222. doi: 10.1159/000458539. Epub 2017 Apr 20.
Impact factor:
Publication type: Clinical guide
Authors: Bandello, Francesco; Berg, Karina; Chakravarthy, Usha; Garcia-Arumi, Jose; Gerendas, Bianca S; Jonas, Jost; Larsen, Michael; Loewenstein, Anat; Schmidt-Erfurth, Ursula; Tadayoni, Ramin et al.
DOI: 10.1159/000458539

Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review.

PMID: 28348882
Journal: Journal of Ophthalmology
Year: 2017
Reference: J Ophthalmol. 2017;2017:2407037. doi: 10.1155/2017/2407037. Epub 2017 Feb 27.
Impact factor:
Publication type: Review in international publication
Authors: Boixadera, Anna; Distefano, Laura N; Garcia-Arumi, Jose; Martinez-Castillo, Vicente et al.
DOI: 10.1155/2017/2407037

Radius of curvature changes in spontaneous improvement of foveoschisis in highly myopic eyes.

PMID: 26130673
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2016
Reference: Br J Ophthalmol. 2016 Feb;100(2):222-6. doi: 10.1136/bjophthalmol-2015-306628. Epub 2015 Jun 30.
Impact factor: 3.036
Publication type: Paper in international publication
Authors: Sherwood, Pamela R, Chang, Stanley, Garcia-Arumi, Jose, Chen, Ching-Lung, Hoang, Quan V et al.
DOI: 10.1136/bjophthalmol-2015-306628

Pars Plana Vitrectomy Alone for the Management of Pseudophakic Rhegmatogenous Retinal Detachment with Only Inferior Breaks.

PMID: 27126928
Journal: OPHTHALMOLOGY
Year: 2016
Reference: Ophthalmology. 2016 Jul;123(7):1563-9. doi: 10.1016/j.ophtha.2016.03.032. Epub 2016 Apr 26.
Impact factor: 6.75
Publication type: Paper in international publication
Authors: Martinez-Castillo, Vicente J, Garcia-Arumi, Jose, Boixadera, Anna et al.
DOI: 10.1016/j.ophtha.2016.03.032

Comparative study of human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC) as a treatment for retinal dystrophies.

PMID: 27006969
Journal: Molecular Therapy-Nucleic Acids
Year: 2016
Reference: Mol Ther Methods Clin Dev. 2016 Mar 16;3:16010. doi: 10.1038/mtm.2016.10. eCollection 2016.
Impact factor: 5.048
Publication type: Paper in international publication
Authors: Riera, Marina, Fontrodona, Laura, Albert, Silvia, Ramirez, Diana Mora, Seriola, Anna, Salas, Anna, Munoz, Yolanda, Ramos, David, Villegas-Perez, Maria Paz, Zapata, Miguel Angel et al.
DOI: 10.1038/mtm.2016.10

ENDORESECTION TECHNIQUE WITH/WITHOUT BRACHYTHERAPY FOR MANAGEMENT OF HIGH POSTERIOR CHOROIDAL MELANOMA: Extended Follow-up Results.

PMID: 25462434
Journal: RETINA-J RET VIT DIS
Year: 2015
Reference: Retina. 2015 Apr;35(4):628-37. doi: 10.1097/IAE.0000000000000379.
Impact factor:
Publication type: Paper in international publication
Authors: Corcostegui, Borja; Dinares-Fernandez, M Carme; Garcia-Arumi, Jose; Leila, Mahmoud; Tresserra, Francesc; Velazquez, Daniel; Zapata, Miguel Angel et al.
DOI: 10.1097/IAE.0000000000000379

Management of Vision-Threatening Complications of Vasoproliferative Tumors of the Retina.

PMID: 26065358
Journal: OPHTHALMIC RES
Year: 2015
Reference: Ophthalmic Res. 2015;54(1):34-40. doi: 10.1159/000430955. Epub 2015 Jun 6.
Impact factor:
Publication type: Paper in international publication
Authors: Corcostegui, Borja; Distefano, Laura N; Fonollosa, Alex; Garcia-Arumi, Jose; Quijano, Claudia et al.
DOI: 10.1159/000430955

A review of current management of vitreomacular traction and macular hole.

PMID: 25821592
Journal: J OPHTHALMOL
Year: 2015
Reference: J Ophthalmol. 2015;2015:809640. doi: 10.1155/2015/809640. Epub 2015 Mar 3.
Impact factor:
Publication type: Paper in international publication
Authors: Arias-Barquet, Lluis; Cabrera-Lopez, Francisco; Figueroa, Marta S; Garcia-Arumi, Jose; Garcia-Layana, Alfredo; Ruiz-Moreno, Jose M et al.
DOI: 10.1155/2015/809640

Comparative study between fundus autofluorescence and red reflectance imaging of choroidal nevi using ultra-wide-field scanning laser ophthalmoscopy.

PMID: 25650707
Journal: RETINA-J RET VIT DIS
Year: 2015
Reference: Retina. 2015 Jun;35(6):1202-10. doi: 10.1097/IAE.0000000000000463.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Arumi, Jose; Leila, Mahmoud; Teixidor, Teresa; Zapata, Miguel Angel et al.
DOI: 10.1097/IAE.0000000000000463

Age-Related Macular Degeneration: Clinical Findings following Treatment with Antiangiogenic Drugs.

PMID: 24693418
Journal: Journal of Ophthalmology
Year: 2014
Reference: J Ophthalmol. 2014;2014:346360. doi: 10.1155/2014/346360. Epub 2014 Feb 16.
Impact factor:
Publication type: Paper in international publication
Authors: Casaroli-Marano, Ricardo; Donate Lopez, Juan; Farres Marti, Jordi; Fernandez-Baca Vaca, Gustavo; Fernandez-Blanco, Clemencia Torron; Figueroa, Marta S; Gallego-Pinazo, Roberto; Garcia-Arumi, Jose; Pina Marin, Begona; Pinero-Bustamante, Antonio et al.
DOI: 10.1155/2014/346360

Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?

PMID: 24672708
Journal: Journal of Ophthalmology
Year: 2014
Reference: J Ophthalmol. 2014;2014:901686. Epub 2014 Jan 23.
Impact factor:
Publication type: Review in international publication
Authors: Araiz, Javier; Arias, Luis; Casaroli-Marano, Ricardo; Diaz-Llopis, Manuel; Gallego-Pinazo, Roberto; Garcia-Layana, Alfredo; Garcia-Medina, Jose J; Gomez-Ulla, Francisco; Lopez-Galvez, Maria Isabel; Manzanas, Lucia et al.
DOI: 10.1155/2014/901686

Intravitreal bevacizumab for choroidal neovascularization associated with Best's disease.

PMID: 24508228
Journal: Archivos de la Sociedad Espanola de Oftalmologia
Year: 2014
Reference: Arch Soc Esp Oftalmol. 2014 Oct;89(10):405-7. doi: 10.1016/j.oftal.2013.07.002. Epub 2014 Feb 5.
Impact factor:
Publication type: Letter or abstract
Authors: Arcos-Algaba, G; Garcia-Arumi, J; Macia Badia, C; Martinez-Castillo, V; Rigo Quera, J; Velazquez-Villoria, D; Velez-Escola, L et al.
DOI: 10.1016/j.oftal.2013.07.002

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives.

PMID: 24183659
Journal: TRENDS IN ENDOCRINOLOGY AND METABOLISM
Year: 2014
Reference: Trends Endocrinol Metab. 2014 Jan;25(1):23-33. doi: 10.1016/j.tem.2013.09.005. Epub 2013 Nov 1.
Impact factor:
Publication type: Paper in international publication
Authors: Bandello, F; Burks, D; Cunha-Vaz, J; Egan, C; Garcia-Arumi, J; Gibson, J; Grauslund, J; Harding, S; Hernandez, Cristina; Karadeniz, S et al.
DOI: 10.1016/j.tem.2013.09.005

Retinal Venous Occlusions: Diagnosis and Choice of Treatments.

PMID: 23406678
Journal: OPHTHALMIC RESEARCH
Year: 2013
Reference: Ophthalmic Res. 2013;49(4):215-22. doi: 10.1159/000346734. Epub 2013 Feb 8.
Impact factor:
Publication type: Review in international publication
Authors: Badal, Josep; Bandello, Francesco; Boixadera, Ana; Casalino, Giuseppe; Castillo, Vicente Martinez; Garcia-Arumi, Jose; Querques, Giuseppe; Triolo, Giacinto; Zapata, Miguel et al.
DOI: 10.1159/000346734

Correspondence to: Intravitreal tumor necrosis factor inhibitors in the treatment of refractory diabetic macular edema: a pilot study from the Pan-American Collaborative Retina Study Group.

PMID: 23624520
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2013
Reference: Retina. 2013 Jun;33(6):1285-7. doi: 10.1097/IAE.0b013e31828bcb15.
Impact factor: 2.825
Publication type: Letter whit IF
Authors: Zapata, Miguel A, Suarez, Joel, Minoves, Teresa, Moncho, Dulce, Farriols, Anna, Garcia-Arumi, Jose et al.
DOI: 10.1097/IAE.0b013e31828bcb15

Spectral-domain optical coherence tomography study of macular structure as prognostic and determining factor for macular hole surgery outcome.

PMID: 23584694
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2013
Reference: Retina. 2013 Jun;33(6):1117-22. doi: 10.1097/IAE.0b013e318285cc3b.
Impact factor: 2.825
Publication type: Paper in international publication
Authors: Ruiz-Moreno, Jose M, Arias, Luis, Araiz, Javier, Garcia-Arumi, Jose, Montero, Javier A, Pinero, David P et al.
DOI: 10.1097/IAE.0b013e318285cc3b

Dexamethasone intravitreal implant for treatment of patients with recalcitrant macular edema resulting from Irvine-Gass syndrome.

PMID: 23599334
Journal: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Year: 2013
Reference: Invest Ophthalmol Vis Sci. 2013 May 7;54(5):3320-4. doi: 10.1167/iovs.12-11463.
Impact factor: 3.441
Publication type: Paper in international publication
Authors: Dutra Medeiros, Marco, Mateo, Carlos, Corcostegui, Borja, Garcia-Arumi, Jose, Navarro, Rafael et al.
DOI: 10.1167/iovs.12-11463

Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications.

PMID: 22887976
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2012
Reference: Br J Ophthalmol. 2012 Oct;96(10):1285-90. Epub 2012 Aug 11.
Impact factor:
Publication type: Review in international publication
Authors: Arce, R; Bandello, F; Burks, D; Cunha-Vaz, J; Egan, C; Garcia-Arumi, J; Gibson, J; Harding, SP; Hernandez, Cristina; Karadeniz, S et al.
DOI: 10.1136/bjophthalmol-2012-302005

23-G Pars Plana Vitrectomy, Lensectomy, and Artisan IOL Implantation for the Management of Nontraumatic Ectopia Lentis: A New Iris Enclavation Technique for Iris Claw Lens.

PMID: 22643806
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2012
Reference: Retina. 2012 Jun;32(6):1214-6.
Impact factor:
Publication type: Editorail in international publication
Authors: Castany-Aregall, Marta; Catala-Mora, Jaume; Diaz-Cascajosa, Jesus; Ferreruela-Sanfeliu, Guillem; Garcia-Arumi, Jose; Prat-Bartomeu, Joan et al.
DOI: 10.1097/IAE.0b013e31824d4f06

Epiretinal membrane after pars plana vitrectomy for primary pseudophakic or aphakic rhegmatogenous retinal detachment: incidence and outcomes.

PMID: 22414957
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2012
Reference: Retina. 2012 Jul;32(7):1350-5.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1097/IAE.0b013e318242b965

Photodynamic therapy for symptomatic subretinal fluid related to choroidal nevus.

PMID: 22366902
Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
Year: 2012
Reference: Retina. 2012 May;32(5):936-41. doi: 10.1097/IAE.0b013e318232c366.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1097/IAE.0b013e318232c366

Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion.

PMID: 20417567
Journal: OPHTHALMOLOGY
Year: 2010
Reference: Ophthalmology. 2010 Jun;117(6):1134-1146.e3. Epub 2010 Apr 24.
Impact factor:
Publication type: Paper in international publication
Authors: Aaberg, Thomas M; Abraham, Prema; Abujamra, Suel; Acton, James; Adamczyk-Ludyga, Aneta; Adenwalla, Mohamed; Agahigian, David D; Agoas, Vitor; Aguilar-Mendoza, Miguel; Aisenbrey, Sabine et al.
DOI: 10.1016/j.ophtha.2010.03.032

Insulin resistance and diabetic macular oedema in type 2 diabetes mellitus.

PMID: 20542983
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2010
Reference: Br J Ophthalmol. 2010 Sep;94(9):1230-2. Epub 2010 Jun 11.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1136/bjo.2009.171702

Bilateral anterior ischemic optic neuropathy in patients on dialysis: A report of two cases.

PMID: 20535272
Journal: Indian Journal of Nephrology
Year: 2010
Reference: Indian J Nephrol. 2010 Jan;20(1):48-50.
Impact factor:
Publication type: Letter or abstract
Authors: Nieto, J; Zapata, M A et al.
DOI: 10.4103/0971-4065.62094

Vitreous levels of interleukine-8 and monocyte chemoattractant protein-1 in macular oedema with branch retinal vein occlusion.

PMID: 20111061
Journal: EYE
Year: 2010
Reference: Eye (Lond). 2010 Jul;24(7):1284-90. Epub 2010 Jan 29.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/eye.2009.340

Conjunctival cytology in floppy eyelid syndrome: objective assessment of the outcome of surgery.

PMID: 19060014
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2009
Reference: Br J Ophthalmol. 2009 Apr;93(4):513-7.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, T; Bisbe, L; Calatayud, M; Garcia-Arumi, J; Medel, R; Vela, J I et al.
DOI: 10.1136/bjo.2008.144287

Transconjunctival sutureless 23-gauge vitrectomy for diabetic retinopathy. Review.

PMID: 19199901
Journal: Curr Diabetes Rev
Year: 2009
Reference: Curr Diabetes Rev. 2009 Feb;5(1):63-6.
Impact factor:
Publication type: Letter or abstract
Authors: Arumi, Jose G; Boixadera, Anna; Corcostegui, Borja; Martinez-Castillo, Vicente et al.
DOI:

Prospective clinical trial evaluating the efficacy of photodynamic therapy for symptomatic circumscribed choroidal hemangioma.

PMID: 18973950
Journal: OPHTHALMOLOGY
Year: 2009
Reference: Ophthalmology. 2009 Jan;116(1):100-105.e1.
Impact factor:
Publication type: Paper in international publication
Authors: Armada, Felix; Blanco-Mateos, Gonzalo; Boixadera, Anna; Caminal, Jose; Capeans, Carmela; Elizalde, Javier; Encinas, Jose Luis; Garcia-Arumi, Jose; Martinez-Castillo, Vicente; Navea, Amaparo et al.
DOI: 10.1016/j.ophtha.2008.08.029

Ocular syphilis--back again: understanding recent increases in the incidence of ocular syphilitic disease.

PMID: 19585365
Journal: OCULAR IMMUNOLOGY AND INFLAMMATION
Year: 2009
Reference: Ocul Immunol Inflamm. 2009 May-Jun;17(3):207-12.
Impact factor:
Publication type: Paper in international publication
Authors: Adan, Alfredo; Fonollosa, Alex; Garcia-Arumi, Jose; Giralt, Joan; Pelegrin, Laura; Sanchez-Dalmau, Bernat; Segura, Antonio et al.
DOI: 10.1080/09273940902741709

Blog

News

On January 24, a session was held to explain what these three-dimensional models are and what advantages they have, as well as to review some of their applications in research.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Dr. José García Arumi and Dr. Anna Duarri from the Ophthalmology research group at Vall Hebron Recerca lead the project.