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Ophtalmology

The clinical and basic research activity of the Ophthalmology Research Group is dedicated to finding new treatments for blindness through the development of new therapies for macular and retinal degenerative diseases, as well as for retinal vascular diseases (diabetic retinopathy and retinal vascular occlusions). Our group consists of core researchers and clinical researchers, so there is a clear clinical translation of the ongoing research in the research group.

We have a research program for the development of new therapeutic strategies based on:

  • Cell therapies
  • Formulations of ocular solutions (LUCIA PI18 and CELLUX EuroNanoMed/AC19)
  • Biological matrices
  • Gene therapy
  • Animal models
  • Retinal cell models based on stem cell-derived organoids.

In the clinical part, the research group bases its activity on clinical trials to develop new treatments for retinal diseases as well as on the ophthalmic involvement of systemic treatments, an example is the phase II trial to test mesenchymal cells (MSV) intravitreal in non-arteritic ischemic optic neuropathy (NAION), the RECOGNISED study or the PULSAR study with aflibercept.

Team

Alfredo Pueyo Ferrer

Alfredo Pueyo Ferrer

Predoctoral researcher
Ophtalmology
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Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
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Sara Martin Nalda

Sara Martin Nalda

Predoctoral researcher
Ophtalmology
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Laia Bisbe López

Laia Bisbe López

Predoctoral researcher
Ophtalmology
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Marta Castany Aregall

Marta Castany Aregall

Ophtalmology
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Silvia Alarcón Portabella

Silvia Alarcón Portabella

Research assistant
Ophtalmology
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Alfredo Pueyo Ferrer

Alfredo Pueyo Ferrer

Predoctoral researcher
Ophtalmology
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Sandra Gonzalez Campos

Sandra Gonzalez Campos

Research assistant
Ophtalmology
Read more
Sara Martin Nalda

Sara Martin Nalda

Predoctoral researcher
Ophtalmology
Read more
Laia Bisbe López

Laia Bisbe López

Predoctoral researcher
Ophtalmology
Read more
Marta Castany Aregall

Marta Castany Aregall

Ophtalmology
Read more
Silvia Alarcón Portabella

Silvia Alarcón Portabella

Research assistant
Ophtalmology
Read more

Research lines

Non-viral gene therapy with Pigment Epithelium-Derived Factor (PEDF) in the treatment of dry and wet forms of AMD

IP: -

Projects

Plataforma ISCIII de Biomodelos y Biobancos

IP: Isabel Novoa Garcia
Collaborators: Shirley Guzmán Avilés, Joaquim Vives Armengol, Anna Duarri Piqué, Eva Colas Ortega, Oriol Bestard Matamoros, Marta Rosal Fontana, Carmen Espejo Ruiz, Marielle Esteves Coelho, Juan Jose Gonzalez Lopez, Sheyla Pascual Martín, Alejandro Tomasello Weitz
Funding agency: Instituto de Salud Carlos III
Funding: 137460
Reference: PT23/00040
Duration: 01/01/2024 - 31/12/2026

(DIGITAL RETINA) - Análisis masivo de datos de bioimagen para el desarrollo de terapias celulares para enfermedades degenerativas de la retina

IP: Miguel Angel Zapata Victori
Collaborators: -
Funding agency: Ministerio Ciencia, Innovación y Universidades
Funding: 188760
Reference: PID2021-122807OB-C32
Duration: 01/09/2022 - 31/08/2026

Ministerio de Ciencia

RETVISION: Del diagnóstico genético molecular a las terapias avanzadas para tratar las enfermedades degenerativas de la retina.

IP: José García Arumí
Collaborators: María Antolín Mate, Anna Duarri Piqué, Claudia Garcia-Arumí Fusté, Miguel Angel Zapata Victori, Laura Natalia Distefano
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI22/01747
Duration: 01/01/2023 - 30/06/2027

Estudio de seguridad y eficacia de la sitagliptina en colirio para el tratamiento de los estadios iniciales de retinopatía diabética.

IP: Rafael Simó Canonge
Collaborators: José García Arumí, Cristina Hernández Pascual, Estudio de seguridad y eficacia de la sitagliptina en colirio para el tratamiento de los estadios iniciales de retinopatía diabé, Cristina Pérez Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 573650
Reference: ICI20/00129
Duration: 01/01/2021 - 31/10/2026

Blog

News

On January 24, a session was held to explain what these three-dimensional models are and what advantages they have, as well as to review some of their applications in research.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

Dr. José García Arumi and Dr. Anna Duarri from the Ophthalmology research group at Vall Hebron Recerca lead the project.