About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of design and pharmacodynamics of nanoparticles at the Vall d’Hebron Research Institute focuses on the synthesis, characterization, and applications of engineered inorganic nanoparticles in the field of medicine. By mastering the inorganic core (size, structure, and shape) and understanding and controlling the linking of molecules to the nanoparticle surface, we engineer nanoparticles that can interact with biological systems in a specific way. We also put particular emphasis on safety, feasibility, scale-up, applicability, and other aspects of nanoparticle design.
Our group is led by Prof. Víctor Puntes, who holds an ICREA Research Professorship. Since a great part of our work demands highly multidisciplinary expertise, we maintain several strong collaborations with biologists, immunologists, oncologists, physicists, environmentalists, and more, from all over Europe, China and the US. The work of the group has resulted in several patents and the creation of several spin-offs such as Nanotargeting and Applied nanoparticles.
PMID: 33676214 Journal: SCIENCE OF THE TOTAL ENVIRONMENT Year: 2021 Reference: Sci Total Environ. 2021 Jul 10;777:145969. doi: 10.1016/j.scitotenv.2021.145969. Epub 2021 Feb 19. Impact factor: Publication type: Paper in international publication Authors: Baranska, Maja; Barrena, Raquel; Capell, Georgina; Font, Xavier; Moral-Vico, Javier; Puntes, Victor; Sanchez, Antoni; Vargas-Garcia, Maria Del Carmen et al. DOI: 10.1016/j.scitotenv.2021.145969
PMID: 33367345 Journal: Nanoscale Year: 2021 Reference: Nanoscale. 2021 Jan 14;13(2):980-990. doi: 10.1039/d0nr06356h. Epub 2020 Dec 24. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus; Lisdat, Fred; Parak, Wolfgang J; Patarroyo, Javier; Puntes, Victor; Riedel, Marc; Yue, Zhao; Zhao, Shuang et al. DOI: 10.1039/d0nr06356h
PMID: 33458959 Journal: Small Year: 2021 Reference: Small. 2021 Apr;17(15):e2006012. doi: 10.1002/smll.202006012. Epub 2021 Jan 18. Impact factor: Publication type: Paper in international publication Authors: Bastus, Neus G; Biehl, Margit; Dubaj, Tibor; Dusinska, Maria; Elje, Elisabeth; Gabelova, Alena; Hesler, Michelle; Kapur, Nikil; Knoll, Thorsten; Kohl, Yvonne et al. DOI: 10.1002/smll.202006012
PMID: 33254802 Journal: JOURNAL OF HAZARDOUS MATERIALS Year: 2021 Reference: J Hazard Mater. 2021 Jan 15;402:123793. doi: 10.1016/j.jhazmat.2020.123793. Epub 2020 Aug 30. Impact factor: Publication type: Paper in international publication Authors: Alijagic, Andi; Barbero, Francesco; Bastus, Neus G; Benada, Oldrich; Gaglio, Daniela; Kofronova, Olga; Napodano, Elisabetta; Pinsino, Annalisa; Puntes, Victor F et al. DOI: 10.1016/j.jhazmat.2020.123793
PMID: 29199832 Journal: LANGMUIR Year: 2017 Reference: Langmuir. 2017 Dec 19;33(50):14502-14512. doi: 10.1021/acs.langmuir.7b03318. Epub 2017 Dec 4. Impact factor: Publication type: Paper in international publication Authors: Jaime, Carlos; Puntes, Victor F; Raman, Asli et al. DOI: 10.1021/acs.langmuir.7b03318
PMID: 29104700 Journal: Cancer nanotechnology Year: 2017 Reference: Cancer Nanotechnol. 2017;8(1):7. doi: 10.1186/s12645-017-0030-4. Epub 2017 Oct 26. Impact factor: Publication type: Review in national publication Authors: Casals, Eudald; Cobaleda-Siles, Macarena; Garcia-Sanz, Ana; Gusta, Muriel F; Puntes, Victor F et al. DOI: 10.1186/s12645-017-0030-4
PMID: 29066063 Journal: SEMINARS IN IMMUNOLOGY Year: 2017 Reference: Semin Immunol. 2017 Dec;34:52-60. doi: 10.1016/j.smim.2017.10.001. Epub 2017 Oct 21. Impact factor: Publication type: Review in national publication Authors: Barbero, Francesco; Bastus, Neus G; Borrajo, Mireya L; Busquets-Fite, Marti; Casals, Eudald; Grandori, Rita; Piella, Jordi; Puntes, Victor; Russo, Lorenzo; Salvo, Ignacio et al. DOI: 10.1016/j.smim.2017.10.001
PMID: 28855907 Journal: Frontiers in Immunology Year: 2017 Reference: Front Immunol. 2017 Aug 14;8:970. doi: 10.3389/fimmu.2017.00970. eCollection 2017. Impact factor: Publication type: Review in national publication Authors: Casals, Eudald; Casals, Gregori; Gusta, Muriel F; Jimenez, Wladimiro; Piella, Jordi; Puntes, Victor et al. DOI: 10.3389/fimmu.2017.00970
PMID: NOPMID3 Journal: Journal of Materials Chemistry A Year: 2016 Reference: J. Mater. Chem. A, 2016,4, 200-208 Impact factor: Publication type: Paper in international publication Authors: Edgar Gonzalez; Florind Merkoçi; Joan Esteve; Jordi Arbiol; Neus G Bastus; Raul Arenal; Victor Puntes et al. DOI: 10.1039/C5TA07504A
PMID: 26495872 Journal: BRITISH JOURNAL OF RADIOLOGY Year: 2016 Reference: Br J Radiol. 2016;89(1057):20150210. doi: 10.1259/bjr.20150210. Epub 2015 Oct 23. Impact factor: Publication type: Paper in international publication Authors: Puntes, Victor et al. DOI: 10.1259/bjr.20150210