About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of design and pharmacodynamics of nanoparticles at the Vall d’Hebron Research Institute focuses on the synthesis, characterization, and applications of engineered inorganic nanoparticles in the field of medicine. By mastering the inorganic core (size, structure, and shape) and understanding and controlling the linking of molecules to the nanoparticle surface, we engineer nanoparticles that can interact with biological systems in a specific way. We also put particular emphasis on safety, feasibility, scale-up, applicability, and other aspects of nanoparticle design.
Our group is led by Prof. Víctor Puntes, who holds an ICREA Research Professorship. Since a great part of our work demands highly multidisciplinary expertise, we maintain several strong collaborations with biologists, immunologists, oncologists, physicists, environmentalists, and more, from all over Europe, China and the US. The work of the group has resulted in several patents and the creation of several spin-offs such as Nanotargeting and Applied nanoparticles.
PMID: 34835755 Journal: Nanomaterials Year: 2021 Reference: Nanomaterials (Basel). 2021 Nov 6;11(11). pii: nano11112991. doi: 10.3390/nano11112991. Impact factor: 5.076 Publication type: Review in international publication Authors: Ernst, Lena M, Casals, Eudald, Italiani, Paola, Boraschi, Diana, Puntes, Victor et al. DOI: 10.3390/nano11112991
PMID: 34394703 Journal: Nano Today Year: 2021 Reference: Nano Today. 2021 Feb;36. doi: 10.1016/j.nantod.2020.101056. Epub 2020 Dec 20. Impact factor: 20.722 Publication type: Paper in international publication Authors: Buzon, Maria J, Puntes, Victor, Genesca, Meritxell, Astorga-Gamaza, Antonio, Vitali, Michele, Borrajo, Mireya L, Jaime, Carlos, Bastus, Neus, Serra-Peinado, Carla, Luque-Ballesteros, Laura et al. DOI: 10.1016/j.nantod.2020.101056
PMID: 28447703 Journal: Nanoscale Year: 2017 Reference: Nanoscale. 2017 May 11;9(18):6111-6121. doi: 10.1039/c7nr00947j. Impact factor: Publication type: Paper in international publication Authors: Brust, Mathias; Casals, Eudald; Garcia-Fernandez, Lorena; Garcia-Pardo, Javier; Lorenzo, Julia; Prior, Ian; Puntes, Victor F; Tort, Olivia et al. DOI: 10.1039/c7nr00947j
PMID: 28290206 Journal: ACS Nano Year: 2017 Reference: ACS Nano. 2017 Mar 28;11(3):2313-2381. doi: 10.1021/acsnano.6b06040. Epub 2017 Mar 14. Impact factor: Publication type: Review in international publication Authors: Alexiou, Christoph; Alvarez-Puebla, Ramon A; Alves, Frauke; Andrews, Anne M; Ashraf, Sumaira; Ballerini, Laura; Balogh, Lajos P; Bestetti, Alessandra; Bosi, Susanna; Brendel, Cornelia et al. DOI: 10.1021/acsnano.6b06040