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Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function. 

 

Team

Matteo Pusceddu

Matteo Pusceddu

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Natalia Borruel Sainz

Natalia Borruel Sainz

Physiology and Pathophysiology of the Digestive Tract
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Ronald Benjamin Llerena Castro

Ronald Benjamin Llerena Castro

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Virginia Robles Alonso

Virginia Robles Alonso

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Matteo Pusceddu

Matteo Pusceddu

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Natalia Borruel Sainz

Natalia Borruel Sainz

Physiology and Pathophysiology of the Digestive Tract
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Ronald Benjamin Llerena Castro

Ronald Benjamin Llerena Castro

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Virginia Robles Alonso

Virginia Robles Alonso

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Publications

Work productivity and activity impairment in disorders of gut-brain interaction: Data from the Rome Foundation Global Epidemiology Study.

PMID: 37332146
Journal: United European Gastroenterology Journal
Year: 2023
Reference: United European Gastroenterol J. 2023 Jun 18. doi: 10.1002/ueg2.12425.
Impact factor:
Publication type: Paper in international publication
Authors: Andresen, Viola; Bangdiwala, Shrikant I; Benninga, Marc A; Corazziari, Enrico S; Frandemark, Asa; Fukudo, Shin; Hreinsson, Johann Pall; Mulak, Agata; Palsson, Olafur S; Santos, Javier et al.
DOI: 10.1002/ueg2.12425

Gut microbial dysbiosis in patients with Cushing's disease in long-term remission. Relationship with cardiometabolic risk.

PMID: 37342265
Journal: Frontiers in Endocrinology
Year: 2023
Reference: Front Endocrinol (Lausanne). 2023 Jun 5;14:1074757. doi: 10.3389/fendo.2023.1074757. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Amodru, Vincent; Fernandez, Pedro Gonzalez; Gaztambide, Sonia; Manichanh, Chaysavanh; Martel-Duguech, Luciana; Puig-Domingo, Manel; Valassi, Elena; Webb, Susan M; Yanez, Francisca et al.
DOI: 10.3389/fendo.2023.1074757

An integral approach to the molecular diagnosis of tuberous sclerosis complex: the role of mosaicism and splicing variants.

PMID: 37356622
Journal: JOURNAL OF MOLECULAR DIAGNOSTICS
Year: 2023
Reference: J Mol Diagn. 2023 Jun 23:S1525-1578(23)00134-4. doi: 10.1016/j.jmoldx.2023.06.006.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Blasco-Perez, Laura; Camprodon-Gomez, Maria; Garcia-Arumi, Elena; Iranzo-Nuez, Leticia; Lopez-Ortega, Ricard; Martinez-Cruz, Desiree; Tenes, Anna; Tizzano, Eduardo F et al.
DOI: 10.1016/j.jmoldx.2023.06.006

Methods for Evaluating the Efficacy of Medical Castration: A Systematic Review.

PMID: 37444589
Journal: Cancers
Year: 2023
Reference: Cancers (Basel). 2023 Jul 3;15(13):3479. doi: 10.3390/cancers15133479.
Impact factor:
Publication type: Review in international publication
Authors: Aguilar, Adriana; Morote, Juan; Planas, Jacques; Trilla, Enrique et al.
DOI: 10.3390/cancers15133479

The Process of Developing a Disease Activity Index in Microscopic Colitis.

PMID: 34562005
Journal: Journal of Crohns & Colitis
Year: 2022
Reference: J Crohns Colitis. 2022 Mar 14;16(3):452-459. doi: 10.1093/ecco-jcc/jjab170.
Impact factor:
Publication type: Paper in international publication
Authors: Bonderup, Ole; Fernandez-Banares, Fernando; Guagnozzi, Danila; Hjortswang, Henrik; Kupcinskas, Juozas; Latella, Giovanni; Lesnovska, Katarina Pihl; Madisch, Ahmed; Magro, Fernando; Miehlke, Stephan et al.
DOI: 10.1093/ecco-jcc/jjab170

Adherence improvement in patients with ulcerative colitis: a multidisciplinary consensus document.

PMID: 34254522
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2022
Reference: Rev Esp Enferm Dig. 2022 Mar;114(3):156-165. doi: 10.17235/reed.2021.8130/2021.
Impact factor:
Publication type: Paper in national publication
Authors: Barreiro-de Acosta, Manuel; Bella Castillo, Pablo; Cabez, Ana; Camacho, Laura; Casellas, Francesc; Fortes, Pilar; Garcia-Lopez, Santiago; Ginard Vicens, Daniel; Gomez, Susana; Gonzalez-Lama, Yago et al.
DOI: 10.17235/reed.2021.8130/2021

A faecal microbiota signature with high specificity for pancreatic cancer.

PMID: 35260444
Journal: GUT
Year: 2022
Reference: Gut. 2022 Jul;71(7):1359-1372. doi: 10.1136/gutjnl-2021-324755. Epub 2022 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Akanni, Wasiu A; Alashkar Alhamwe, Bilal; Alfaro, Ana; Alonso, Lola; Alvarez-Urturi, Cristina; Alves, Renato J; Artigas, Vicenc; Balcells, Joaquin; Barneo, LuSis; Beghelli, Stefania et al.
DOI: 10.1136/gutjnl-2021-324755

The Intestinal Gas Questionnaire (IGQ): Psychometric validation of a new instrument for measuring gas-related symptoms and their impact on daily life among general population and irritable bowel syndrome.

PMID: 34145682
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Mar;34(3):e14202. doi: 10.1111/nmo.14202. Epub 2021 Jun 18.
Impact factor:
Publication type: Paper in international publication
Authors: Archbold, Sharon; Azpiroz, Fernando; Bessonneau, Pascal; Chassany, Olivier; Coffin, Benoit; Duracinsky, Martin; Guagnozzi, Danila; Lobo, Beatriz; Payakachat, Nalin; Santos, Javier et al.
DOI: 10.1111/nmo.14202

Blastocystis sp. Carriage and Irritable Bowel Syndrome: Is the Association Already Established?

PMID: 33921803
Journal: Biology-Basel
Year: 2021
Reference: Biology (Basel). 2021 Apr 19;10(4). pii: biology10040340. doi: 10.3390/biology10040340.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Bailo, Begona; Bosch-Nicolau, Pau; Carmena, David; Espinosa-Pereiro, Juan; Fuentes, Isabel; Goterris, Lidia; Lobo, Beatriz; Molina, Israel; Salvador, Fernando et al.
DOI: 10.3390/biology10040340

Long-Term Safety and Efficacy of Prebiotic Enriched Infant Formula-A Randomized Controlled Trial.

PMID: 33924514
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 Apr 13;13(4). pii: nu13041276. doi: 10.3390/nu13041276.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Joaquin; Campoy, Cristina; Guarner, Francisco; Moreno-Munoz, Jose Antonio; Neumer, Franka; Palencia, Jesus; Rodriguez-Palmero, Maria; Theis, Stephan; Urraca, Orenci; Vandenplas, Yvan et al.
DOI: 10.3390/nu13041276

Gastrointestinal Contributions to the Postprandial Experience.

PMID: 33801924
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 Mar 10;13(3). pii: nu13030893. doi: 10.3390/nu13030893.
Impact factor:
Publication type: Review in international publication
Authors: Azpiroz, Fernando; Livovsky, Dan M et al.
DOI: 10.3390/nu13030893

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Position paper on diagnosis, prognosis, and treatment by the MNGIE International Network.

PMID: 32898308
Journal: JOURNAL OF INHERITED METABOLIC DISEASE
Year: 2021
Reference: J Inherit Metab Dis. 2021 Mar;44(2):376-387. doi: 10.1002/jimd.12300. Epub 2020 Sep 8.
Impact factor:
Publication type: Review in international publication
Authors: Accarino, Anna; Baldin, Elisa; Bax, Bridget Elizabeth; Bolletta, Alessio; Bolletta, Riccardo; Boschetti, Elisa; Carelli, Valerio; Cenacchi, Giovanna; Cescon, Matteo; D'Alessandro, Roberto et al.
DOI: 10.1002/jimd.12300

Improving Quality of Care in Inflammatory Bowel Disease Through Patients' Eyes: IQCARO Project.

PMID: 31634907
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2020
Reference: Inflamm Bowel Dis. 2020 Apr 11;26(5):782-791. doi: 10.1093/ibd/izz126.
Impact factor:
Publication type: Paper in international publication
Authors: Calvet, Xavier; Carpio, Daniel; Casellas, Fransesc; Julia, Berta; Marin, Laura; Minguez, Miguel; Saldana, Roberto; Vera, Isabel et al.
DOI: 10.1093/ibd/izz126

Food, Eating, and the Gastrointestinal Tract.

PMID: 32252402
Journal: Nutrients
Year: 2020
Reference: Nutrients. 2020 Apr 2;12(4). pii: nu12040986. doi: 10.3390/nu12040986.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Livovsky, Dan M; Pribic, Teorora et al.
DOI: 10.3390/nu12040986

Testing the Food Experience in Healthy Human Volunteers: a Proof-of-Concept Study.

PMID: 32176761
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2020
Reference: J Gastrointestin Liver Dis. 2020 Mar 13;29(1):65-68. doi: 10.15403/jgld-806.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Livovsky, Dan M; Lopez, Quiro; Lucas, Eduardo; Pareto, Deborah; Pribic, Teodora; Rovira, Alex et al.
DOI: 10.15403/jgld-806

The Brain-Gut Team.

PMID: 32114574
Journal: DIGESTIVE DISEASES
Year: 2020
Reference: Dig Dis. 2020;38(4):293-298. doi: 10.1159/000505810. Epub 2020 Feb 28.
Impact factor:
Publication type: Review in international publication
Authors: Malagelada, Juan R et al.
DOI: 10.1159/000505810

Intestinal Mucosal Mast Cells: Key Modulators of Barrier Function and Homeostasis.

PMID: 30744042
Journal: Cells
Year: 2019
Reference: Cells. 2019 Feb 8;8(2). pii: cells8020135. doi: 10.3390/cells8020135.
Impact factor:
Publication type: Review in national publication
Authors: Albert-Bayo, Merce; Alonso-Cotoner, Carmen; Gonzalez-Castro, Ana M; Paracuellos, Irene; Rodriguez-Lagunas, Maria J; Rodriguez-Urrutia, Amanda; Santos, Javier; Vicario, Maria et al.
DOI: 10.3390/cells8020135

Microcytic anemia due to ileocolic anastomotic ulcer.

PMID: 29588085
Journal: Gastroenterologia y Hepatologia
Year: 2019
Reference: Gastroenterol Hepatol. 2019 Feb;42(2):111-112. doi: 10.1016/j.gastrohep.2018.02.004. Epub 2018 Mar 24.
Impact factor:
Publication type: Letter or abstract
Authors: Alonso-Cotoner, Carmen; Espin Basany, Eloy; Rivera Esteban, Jesus Manuel; Santos Vicente, Javier et al.
DOI: 10.1016/j.gastrohep.2018.02.004

Prevalence and Factors Associated with Fatigue in Patients with Inflammatory Bowel Disease: A Multicenter Study.

PMID: 30721954
Journal: Journal of Crohns & Colitis
Year: 2019
Reference: J Crohns Colitis. 2019 Aug 14;13(8):996-1002. doi: 10.1093/ecco-jcc/jjz024.
Impact factor:
Publication type: Paper in international publication
Authors: Algaba, A; Almela, P; Antolin-Melero, B; Arguelles-Arias, F; Arribas-Lopez, M R; Banales, J M; Barreiro-de Acosta, M; Bujanda, L; Casanova, M J; Casellas, F et al.
DOI: 10.1093/ecco-jcc/jjz024

Pancreatic cancer and autoimmune diseases: An association sustained by computational and epidemiological case-control approaches.

PMID: 30229903
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2019
Reference: Int J Cancer. 2019 Apr 1;144(7):1540-1549. doi: 10.1002/ijc.31866. Epub 2018 Oct 26.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, Joaquim; Barbera, Victor M; Carrato, Alfredo; Costello, Eithne; Crnogorac-Jurcevic, Tatjana; Dominguez-Munoz, Enrique; Farre, Antoni; Furlong, Laura I; Gomez-Rubio, Paulina; Greenhalf, William et al.
DOI: 10.1002/ijc.31866

Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction.

PMID: 29396473
Journal: Scientific Reports
Year: 2018
Reference: Sci Rep. 2018 Feb 2;8(1):2255. doi: 10.1038/s41598-018-20540-9.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Azpiroz, Fernando; Fortea, Marina; Gonzalez-Castro, Ana Maria; Guagnozzi, Danila; Iribarren, Cristina; Lobo, Beatriz; Martinez, Cristina; Nieto, Adoracion; Pardo-Camacho, Cristina et al.
DOI: 10.1038/s41598-018-20540-9

Biogastronomy: Factors that determine the biological response to meal ingestion.

PMID: 29392797
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Jul;30(7):e13309. doi: 10.1111/nmo.13309. Epub 2018 Feb 2.
Impact factor:
Publication type: Review in international publication
Authors: Azpiroz, F; Pribic, T et al.
DOI: 10.1111/nmo.13309

Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.

PMID: 28834270
Journal: LIVER INTERNATIONAL
Year: 2018
Reference: Liver Int. 2018 Feb;38(2):295-302. doi: 10.1111/liv.13551. Epub 2017 Sep 13.
Impact factor:
Publication type: Paper in international publication
Authors: Bellot, Pablo; Frances, Ruben; Garcia, Irma; Gimenez, Paula; Gomez-Hurtado, Isabel; Gonzalez-Navajas, Jose Manuel; Guarner, Francisco; Manichahn, Chaysavanh; Ramos, Jose Manuel; Such, Jose et al.
DOI: 10.1111/liv.13551

Effects of meal palatability on postprandial sensations.

PMID: 29105893
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Feb;30(2). doi: 10.1111/nmo.13248. Epub 2017 Nov 6.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Hernandez, L; Malagelada, C; Nieto, A; Pribic, T et al.
DOI: 10.1111/nmo.13248

Fermented milk containing Lactobacillus paracasei subsp. paracasei CNCM I-1518 reduces bacterial translocation in rats treated with carbon tetrachloride.

PMID: 28368023
Journal: Scientific Reports
Year: 2017
Reference: Sci Rep. 2017 Apr 3;7:45712. doi: 10.1038/srep45712.
Impact factor:
Publication type: Paper in international publication
Authors: Corominola, Helena; Guarner, Carlos; Juarez, Candido; Manichanh, Chaysavanh; Martinez, Xavier; Mirelis, Beatriz; Nieto, Juan C; Sanchez, Elisabet; Sancho, Francesc J; Sancho-Bru, Pau et al.
DOI: 10.1038/srep45712

Colonic content: effect of diet, meals, and defecation.

PMID: 27545449
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2017
Reference: Neurogastroenterol Motil. 2017 Feb;29(2). doi: 10.1111/nmo.12930. Epub 2016 Aug 21.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Bendezu, R A; Malagelada, J R; Mego, M; Merino, X; Monclus, E; Navazo, I et al.
DOI: 10.1111/nmo.12930

Effects of scFOS on the composition of fecal microbiota and anxiety in patients with irritable bowel syndrome: a randomized, double blind, placebo controlled study.

PMID: 27477485
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2017
Reference: Neurogastroenterol Motil. 2017 Feb;29(2). doi: 10.1111/nmo.12911. Epub 2016 Jul 31.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Bernalier-Donadille, A; Cardot, J-M; Dapoigny, M; Dubray, C; Respondek, F; Serra, J; Wagner, A et al.
DOI: 10.1111/nmo.12911

Practical aspects of high resolution esophageal manometry.

PMID: 27990836
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2017
Reference: Rev Esp Enferm Dig. 2017 Feb;109(2):91-105. doi: 10.17235/reed.2016.4441/2016.
Impact factor:
Publication type: Paper in national publication
Authors: Barba Orozco, Elisabeth; Bosque Lopez, Maria Jose; Canga Rodriguez-Valcarcel, Fernando; Carrion Bolorino, Silvia; Casabona Frances, Sergio; Castillo Grau, Pilar; Ciriza de Los Rios, Constanza; Delgado Aros, Silvia; Dominguez Carbajo, Ana Belen; Estremera Arevalo, Fermin et al.
DOI: 10.17235/reed.2016.4441/2016

Development and Validation of the Short Crohn's Disease Work Disability Questionnaire.

PMID: 26933747
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2016
Reference: Inflamm Bowel Dis. 2016 Apr;22(4):955-62. doi: 10.1097/MIB.0000000000000678.
Impact factor:
Publication type: Paper in international publication
Authors: Calvet, Xavier; Casellas, Francesc; Gomollon, Fernando; Prieto, Luis; Ramos, Alexis; Sicilia, Beatriz; Vergara, Mercedes et al.
DOI: 10.1097/MIB.0000000000000678

[Recommendations for the diagnosis, staging and treatment of pre-malignant lesions and pancreatic adenocarcinoma].

PMID: 27726847
Journal: MEDICINA CLINICA
Year: 2016
Reference: Med Clin (Barc). 2016 Nov 18;147(10):465.e1-465.e8. doi: 10.1016/j.medcli.2016.07.033. Epub 2016 Oct 7.
Impact factor:
Publication type: Paper in national publication
Authors: Ayuso, Juan Ramon; Cuatrecasas, Miriam; Fabregat, Joan; Fernandez-Esparrach, Gloria; Ferrandez, Antonio; Gines, Angels; Martin-Richard, Marta; Maurel, Joan; Mendez, Ramiro; Molero, Xavier et al.
DOI: 10.1016/j.medcli.2016.07.033

A weakly acidic solution containing deoxycholic acid induces esophageal epithelial apoptosis and impairs integrity in an in vivo perfusion rabbit model.

PMID: 26797397
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2016
Reference: Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G487-96. doi: 10.1152/ajpgi.00370.2015. Epub 2016 Jan 21.
Impact factor:
Publication type: Paper in international publication
Authors: Ceulemans, Laurens J; Farre, Ricard; Jimenez, Marcel; Pardon, Nicolas A; Tack, Jan; Vanheel, Hanne; Vanuytsel, Tim; Vicario, Maria; Vieth, Michael et al.
DOI: 10.1152/ajpgi.00370.2015

Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease.

PMID: 26642859
Journal: GUT
Year: 2016
Reference: Gut. 2016 May;65(5):830-9. doi: 10.1136/gutjnl-2015-310585. Epub 2015 Dec 7.
Impact factor:
Publication type: Paper in international publication
Authors: Agostini, H; Berrebi, D; Boschat, L; Bruneau, A; Cailleux, F; Cassard, A M; Ciocan, D; Ferrere, G; Gaudin, F; Gerard, P et al.
DOI: 10.1136/gutjnl-2015-310585

[Use of probiotics and prebiotics in primary care].

PMID: 25659055
Journal: NUTR HOSP
Year: 2015
Reference: Nutr Hosp. 2015 Feb 7;31 Suppl 1:59-63. doi: 10.3305/nh.2015.31.sup1.8708.
Impact factor:
Publication type: Paper in national publication
Authors: Alvarez Calatayud, Guillermo; Azpiroz, Fernando et al.
DOI: 10.3305/nh.2015.31.sup1.8708

Increased antibody response in the intestinal mucosa of diarrhoea-prone irritable bowel syndrome in association with psychological stress and abdominal pain.

PMID: 26383484
Journal: PSYCHONEUROENDOCRINO
Year: 2015
Reference: Psychoneuroendocrinology. 2015 Nov;61:75-6. doi: 10.1016/j.psyneuen.2015.07.599. Epub 2015 Aug 8.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Azpiroz, Fernando; Casado-Bedmar, Maite; Fortea, Marina; Gonzalez-Castro, Ana M; Lobo, Beatriz; Pardo-Camacho, Cristina; Rodino-Janeiro, Bruno K; Salvo-Romero, Eloisa; Santos, Javier et al.
DOI: 10.1016/j.psyneuen.2015.07.599

Classification of functional bowel disorders by objective physiological criteria based on endoluminal image analysis.

PMID: 26251472
Journal: AM J PHYSIOL-GASTR L
Year: 2015
Reference: Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G413-9. doi: 10.1152/ajpgi.00193.2015. Epub 2015 Aug 6.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; Drozdzal, Michal; Malagelada, Carolina; Malagelada, Juan-R; Mendez, Sara; Radeva, Petia; Santos, Javier; Segui, Santi; Vitria, Jordi et al.
DOI: 10.1152/ajpgi.00193.2015

Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy.

PMID: 26264513
Journal: BRAIN
Year: 2015
Reference: Brain. 2015 Oct;138(Pt 10):2847-58. doi: 10.1093/brain/awv226. Epub 2015 Aug 10.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Bakker, Jaap A; Barba, Pere; Beguin, Yves; Boelens, Jaap J; Casali, Carlo; Chinnery, Patrick F; Collin, Matthew; de Coo, Irenaeus F M; Dotti, Maria T et al.
DOI: 10.1093/brain/awv226

Intestinal barrier function and the brain-gut axis.

PMID: 24997030
Journal: ADV EXP MED BIOL
Year: 2014
Reference: Adv Exp Med Biol. 2014;817:73-113. doi: 10.1007/978-1-4939-0897-4_4.
Impact factor: 2.012
Publication type: Review in national publication
Authors: Alonso, Carmen, Vicario, Maria, Pigrau, Marc, Lobo, Beatriz, Santos, Javier et al.
DOI: 10.1007/978-1-4939-0897-4_4

Vitamin E and vitamin E acetate absorption from self-assembly systems under pancreas insufficiency conditions.

PMID: 24801842
Journal: CHIMIA
Year: 2014
Reference: Chimia (Aarau). 2014;68(3):129-34. doi: 10.2533/chimia.2014.129.
Impact factor: 1.091
Publication type: Clinical Trials
Authors: Nagy, Kornel, Lobo, Beatriz, Courtet-Compondu, Marie-Claude, Braga-Lagache, Sophie, Ramos, Laura, Puig-Divi, Valenti, Azpiroz, Fernando, Malagelada, Juan Ramon, Beaumont, Maurice, Moulin, Julie et al.
DOI: 10.2533/chimia.2014.129

Decade in review-gut microbiota: The gut microbiota era marches on.

PMID: 25201043
Journal: NAT REV GASTRO HEPAT
Year: 2014
Reference: Nat Rev Gastroenterol Hepatol. 2014 Nov;11(11):647-9. doi: 10.1038/nrgastro.2014.156. Epub 2014 Sep 9.
Impact factor: 10.807
Publication type: Paper in international publication
Authors: Guarner, Francisco et al.
DOI: 10.1038/nrgastro.2014.156

Structure And Functions Of The Gut Microbiome.

PMID: 25022563
Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Year: 2014
Reference: Endocr Metab Immune Disord Drug Targets. 2014;14(4):290-9.
Impact factor: 0
Publication type: Review in international publication
Authors: Panda, Suchita, Guarner, Francisco, Manichanh, Chaysavanh et al.
DOI: 10.2174/1871530314666140714120744

Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission.

PMID: 23385241
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2013
Reference: Inflamm Bowel Dis. 2013 Mar;19(3):481-8. doi: 10.1097/MIB.0b013e31827fec6d.
Impact factor:
Publication type: Paper in international publication
Authors: de Vos, Willem M; Guarner, Francisco; Rajilic-Stojanovic, Mirjana; Shanahan, Fergus et al.
DOI: 10.1097/MIB.0b013e31827fec6d

Abdominal accommodation induced by meal ingestion: differential responses to gastric and colonic volume loads.

PMID: 23360536
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2013
Reference: Neurogastroenterol Motil. 2013 Apr;25(4):339-e253. doi: 10.1111/nmo.12068. Epub 2013 Jan 29.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Burri, E; Cisternas, D; Malagelada, J-R; Soldevilla, A; Villoria, A et al.
DOI: 10.1111/nmo.12068

Epidemiological Risk Factors in Microscopic Colitis: A Prospective Case-Control Study.

PMID: 23344243
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2013
Reference: Inflamm Bowel Dis. 2013 Feb;19(2):411-7. doi: 10.1002/ibd.23009.
Impact factor:
Publication type: Paper in international publication
Authors: Andreu, Montserrat; Beltran, Belen; Calvo, Marta; de Sousa, Monia R; Esteve, Maria; Fernandez-Banares, Fernando; Garcia-Planella, Esther; Gisbert, Javier P; Iglesias, Eva; Lobo, Beatriz et al.
DOI: 10.1002/ibd.23009

Understanding the microbiota in the midst of Renaissance architecture and olive groves.

PMID: 23334821
Journal: NATURE IMMUNOLOGY
Year: 2013
Reference: Nat Immunol. 2013 Feb;14(2):101-5. doi: 10.1038/ni.2512.
Impact factor:
Publication type: Paper in international publication
Authors: Guarner, Francisco; Hooper, Lora V; Nunez, Gabriel et al.
DOI: 10.1038/ni.2512

Guidelines for the use and interpretation of assays for monitoring autophagy.

PMID: 22966490
Journal: Autophagy
Year: 2012
Reference: Autophagy. 2012 Apr;8(4):445-544.
Impact factor: 7.453
Publication type: Review in international publication
Authors: Bai, Xue-Yuan, Albin, Roger L, Alegre-Abarrategui, Javier, Aleo, Maria Francesca, Alirezaei, Mehrdad, Almasan, Alexandru, Almonte-Becerril, Maylin, Amano, Atsuo, Amaravadi, Ravi, Amarnath, Shoba et al.
DOI:

The gut microbiota in IBD.

PMID: 22907164
Journal: Nature Reviews Gastroenterology & Hepatology
Year: 2012
Reference: Nat Rev Gastroenterol Hepatol. 2012 Oct;9(10):599-608. doi: 10.1038/nrgastro.2012.152. Epub 2012 Aug 21.
Impact factor: 8.102
Publication type: Review in international publication
Authors: Manichanh, Chaysavanh, Borruel, Natalia, Casellas, Francesc, Guarner, Francisco et al.
DOI: 10.1038/nrgastro.2012.152

Storage conditions of intestinal microbiota matter in metagenomic analysis.

PMID: 22846661
Journal: BMC MICROBIOLOGY
Year: 2012
Reference: BMC Microbiol. 2012 Jul 30;12:158. doi: 10.1186/1471-2180-12-158.
Impact factor: 3.044
Publication type: Paper in international publication
Authors: Cardona, Silvia, Eck, Anat, Cassellas, Montserrat, Gallart, Milagros, Alastrue, Carmen, Dore, Joel, Azpiroz, Fernando, Roca, Joaquim, Guarner, Francisco, Manichanh, Chaysavanh et al.
DOI: 10.1186/1471-2180-12-158

World gastroenterology organisation global guidelines: probiotics and prebiotics october 2011.

PMID: 22688142
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2012
Reference: J Clin Gastroenterol. 2012 Jul;46(6):468-81.
Impact factor: 3.159
Publication type: Paper in international publication
Authors: de Paula, Juan Andres, Guarner, Francisco, Khan, Aamir G, Garisch, James, Eliakim, Rami, Gangl, Alfred, Thomson, Alan, Krabshuis, Justus, Lemair, Ton, Kaufmann, Pedro et al.
DOI: 10.1097/MCG.0b013e3182549092

Guidelines for the design, conduct and reporting of human intervention studies to evaluate the health benefits of foods.

PMID: 22129662
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2011
Reference: Br J Nutr. 2011 Nov;106 Suppl 2:S3-15.
Impact factor: 3.072
Publication type: Paper in international publication
Authors: Berta, Jean-Louis, Bub, Achim, de Vries, Jan, Guarner, Francisco, Hasselwander, Oliver, Hendriks, Henk, Jakel, Martin, Koletzko, Berthold V, Patterson, Chris C, Richelle, Myriam et al.
DOI: 10.1017/S0007114511003606

A New Validation of the Spanish Work Productivity and Activity Impairment Questionnaire-Crohn's Disease Version.

PMID: 21914506
Journal: VALUE IN HEALTH
Year: 2011
Reference: Value Health. 2011 Sep-Oct;14(6):859-61. Epub 2011 May 28.
Impact factor: 2.342
Publication type: Paper in international publication
Authors: Calvet, Xavier, Gallardo, Olga, Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Villoria, Albert, Suarez, David, Maudsley, Michael, Ricart, Elena et al.
DOI: 10.1016/j.jval.2011.02.1179

Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis.

PMID: 21852363
Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Year: 2011
Reference: Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G846-55. Epub 2011 Aug 18.
Impact factor: 3.522
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1152/ajpgi.00485.2010

Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial).

PMID: 20938444
Journal: INTERNATIONAL JOURNAL OF OBESITY
Year: 2011
Reference: Int J Obes (Lond). 2011 Jun;35(6):829-37. doi: 10.1038/ijo.2010.210. Epub 2010 Oct 12.
Impact factor: 5.125
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1038/ijo.2010.210

Current level of consensus on probiotic science--report of an expert meeting--London, 23 November 2009.

PMID: 21637035
Journal: Gut microbes
Year: 2010
Reference: Gut Microbes. 2010 Nov-Dec;1(6):436-9. doi: 10.4161/gmic.1.6.13610.
Impact factor: 2.19
Publication type: Paper in international publication
Authors: Rowland, Ian, Capurso, Lucio, Collins, Kevin, Cummings, John, Delzenne, Nathalie, Goulet, Olivier, Guarner, Francisco, Marteau, Philippe, Meier, Remy et al.
DOI: 10.4161/gmic.1.6.13610

Consensus statements from the Workshop "Probiotics and Health: Scientific Evidence"

PMID: 21336423
Journal: Nutricion Hospitalaria
Year: 2010
Reference: Nutr Hosp. 2010 Oct;25(5):700-704.
Impact factor: 1.065
Publication type: Paper in national publication
Authors: , , et al.
DOI:

The dysfunctional gut.

PMID: 20582743
Journal: Curr Gastroenterol Rep
Year: 2010
Reference: Curr Gastroenterol Rep. 2010 Aug;12(4):242-8.
Impact factor:
Publication type: Letter or abstract
Authors: Malagelada, Carolina, Malagelada, Juan-R et al.
DOI: 10.1007/s11894-010-0119-y

Crohn s disease, feeling well or healthy?

PMID: 21142381
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2010
Reference: Rev Esp Enferm Dig. 2010 Nov;102(11):621-623.
Impact factor: 0.994
Publication type: Editorial in national publication
Authors: et al.
DOI:

The challenge of developing new therapies for irritable bowel syndrome.

PMID: 21180543
Journal: Therapeutic advances in gastroenterology
Year: 2009
Reference: Therap Adv Gastroenterol. 2009 Jul;2(4):201-3. doi: 10.1177/1756283X09335638.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Whorwell, Peter J, Azpiroz, Fernando et al.
DOI: 10.1177/1756283X09335638

Predictive factors of poor response to intravenous cyclosporine in steroid-refractory ulcerative colitis.

PMID: 19388796
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2009
Reference: Rev Esp Enferm Dig. 2009 Mar;101(3):163-71. doi: 10.4321/s1130-01082009000300002.
Impact factor: 1.263
Publication type: Paper in national publication
Authors: Huaman Rios, J W, Casellas Jorda, F, Malagelada Benapres, J R et al.
DOI: 10.4321/s1130-01082009000300002

[Application of a model of continued attention in inflammatory bowel disease: the Crohn-colitis care unit].

PMID: 19231678
Journal: Gastroenterol Hepatol
Year: 2009
Reference: Gastroenterol Hepatol. 2009 Feb;32(2):77-82. doi: 10.1016/j.gastrohep.2008.09.015. Epub 2009 Feb 5.
Impact factor: 0
Publication type: Paper in national publication
Authors: Casellas Jorda, Francesc, Malagelada Benapres, Juan Ramon, Castillejo Badia, Neus, Borruel Sainz, Natalia, Torrejon Herrera, Antonio, Masachs Peracaula, Miquel, Castells Carner, Isabel et al.
DOI: 10.1016/j.gastrohep.2008.09.015

Validation of the Spanish Work Productivity and Activity impairment questionnaire: Crohn's disease version.

PMID: 19404204
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2009
Reference: Eur J Gastroenterol Hepatol. 2009 Jul;21(7):809-15.
Impact factor: 2.08
Publication type: Paper in international publication
Authors: Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Maudsley, Michael, Gallardo, Olga, Ricart, Elena, Calvet, Xavier et al.
DOI: 10.1097/MEG.0b013e32830f4c9e

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A new diagnostic algorithm has been created to guide professionals in cases of persistent vomiting for more than four weeks.

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.