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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials.

PMID: 34907394
Journal: MOLECULAR PSYCHIATRY
Year: 2022
Reference: Mol Psychiatry. 2022 Mar;27(3):1286-1299. doi: 10.1038/s41380-021-01381-x. Epub 2021 Dec 15.
Impact factor:
Publication type: Review in international publication
Authors: Aislaitner, Georgios; Anderson, Ian M; Aouizerate, Bruno; Arolt, Volker; Arteaga-Henriquez, Gara; Bauer, Michael; Baune, Bernhard T; Benedetti, Francesco; Blier, Pierre; Butlen-Ducuing, Florence et al.
DOI: 10.1038/s41380-021-01381-x

A differential therapeutic consideration for use of corticosteroids according to established COVID-19 clinical phenotypes in critically ill patients.

PMID: 36272908
Journal: Medicina intensiva
Year: 2022
Reference: Med Intensiva (Engl Ed). 2022 Oct 19. pii: S2173-5727(22)00241-7. doi: 10.1016/j.medine.2021.10.016.
Impact factor:
Publication type: Paper in international publication
Authors: Albaya-Moreno, A; Armestar, F; Blasco Cortes, M; Bodi, M; Bonell Goytisolo, J M; Casamitjana Ortega, A M; deAlba-Aparicio, M; Diaz, E; Estella, A; Ferrer, R et al.
DOI: 10.1016/j.medine.2021.10.016

A Drug-Drug Interaction Study to Investigate the Effect of Nintedanib on the Pharmacokinetics of Microgynon (Ethinylestradiol and Levonorgestrel) in Female Patients with Systemic Sclerosis-Associated Interstitial Lung Disease.

PMID: 34664183
Journal: EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
Year: 2022
Reference: Eur J Drug Metab Pharmacokinet. 2022 Jan;47(1):81-89. doi: 10.1007/s13318-021-00728-7. Epub 2021 Oct 18.
Impact factor: 2.448
Publication type: Paper in international publication
Authors: Vonk, Madelon C, Guillen-Del-Castillo, Alfredo, Kreuter, Michael, Avis, Mandy, Marzin, Kristell, Mack, Salome R, Wind, Sven, Gahlemann, Martina et al.
DOI: 10.1007/s13318-021-00728-7

A Drug-Drug Interaction Study to Investigate the Effect of Nintedanib on the Pharmacokinetics of Microgynon (Ethinylestradiol and Levonorgestrel) in Female Patients with Systemic Sclerosis-Associated Interstitial Lung Disease.

PMID: 34664183
Journal: EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
Year: 2022
Reference: Eur J Drug Metab Pharmacokinet. 2022 Jan;47(1):81-89. doi: 10.1007/s13318-021-00728-7. Epub 2021 Oct 18.
Impact factor:
Publication type: Paper in international publication
Authors: Avis, Mandy; Gahlemann, Martina; Guillen-Del-Castillo, Alfredo; Kreuter, Michael; Mack, Salome R; Marzin, Kristell; Vonk, Madelon C; Wind, Sven et al.
DOI: 10.1007/s13318-021-00728-7

A European arena for joint innovation in healthcare: The Platform for Innovation of Procurement and Procurement of Innovation (PiPPi).

PMID: 36711358
Journal: Frontiers in Public Health
Year: 2022
Reference: Front Public Health. 2023 Jan 12;10:1000590. doi: 10.3389/fpubh.2022.1000590. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Ahlberg, Martina; Alessandrello, Rossana; Andrews, Margaret R; Balvert, Fred; Lazzari, Agnese; Long, Preston A; Nouri Janian, Mariet; Rantaniska, Minerva; Soderman, Peter; Spence, Ann et al.
DOI: 10.3389/fpubh.2022.1000590

A faecal microbiota signature with high specificity for pancreatic cancer.

PMID: 35260444
Journal: GUT
Year: 2022
Reference: Gut. 2022 Jul;71(7):1359-1372. doi: 10.1136/gutjnl-2021-324755. Epub 2022 Mar 8.
Impact factor: 23.059
Publication type: Paper in international publication
Authors: Maistrenko, Oleksandr M, Kartal, Ece, Schmidt, Thomas S B, Molina-Montes, Esther, Rodriguez-Perales, Sandra, Wirbel, Jakob, Malats, Nuria, Bork, Peer, Malats, Nuria, Real, Francisco X et al.
DOI: 10.1136/gutjnl-2021-324755

A faecal microbiota signature with high specificity for pancreatic cancer.

PMID: 35260444
Journal: GUT
Year: 2022
Reference: Gut. 2022 Jul;71(7):1359-1372. doi: 10.1136/gutjnl-2021-324755. Epub 2022 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Akanni, Wasiu A; Alashkar Alhamwe, Bilal; Alfaro, Ana; Alonso, Lola; Alvarez-Urturi, Cristina; Alves, Renato J; Artigas, Vicenc; Balcells, Joaquin; Barneo, LuSis; Beghelli, Stefania et al.
DOI: 10.1136/gutjnl-2021-324755

A Feasibility Study of Patients with Major Depression and Substance Use Disorders: Vortioxetine as Maintenance Treatment.

PMID: 35547266
Journal: Neuropsychiatric Disease and Treatment
Year: 2022
Reference: Neuropsychiatr Dis Treat. 2022 May 4;18:965-976. doi: 10.2147/NDT.S358782. eCollection 2022.
Impact factor: 2.57
Publication type: Paper in international publication
Authors: Basurte-Villamor, Ignacio, Vega, Pablo, Roncero, Carlos, Martinez-Raga, Jose, Grau-Lopez, Lara, Aguilar, Lourdes, Torrens, Marta, Szerman, Nestor et al.
DOI: 10.2147/NDT.S358782

A Feasibility Study of Patients with Major Depression and Substance Use Disorders: Vortioxetine as Maintenance Treatment.

PMID: 35547266
Journal: Neuropsychiatric Disease and Treatment
Year: 2022
Reference: Neuropsychiatr Dis Treat. 2022 May 4;18:965-976. doi: 10.2147/NDT.S358782. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Lourdes; Basurte-Villamor, Ignacio; Grau-Lopez, Lara; Martinez-Raga, Jose; Roncero, Carlos; Szerman, Nestor; Torrens, Marta; Vega, Pablo et al.
DOI: 10.2147/NDT.S358782

A first update on mapping the human genetic architecture of COVID-19.

PMID: 35922517
Journal: NATURE
Year: 2022
Reference: Nature. 2022 Aug;608(7921):E1-E10. doi: 10.1038/s41586-022-04826-7. Epub 2022 Aug 3.
Impact factor:
Publication type: Letter or abstract
Authors: Abd Elghafar, Mohamed S; Abdel-Aziz, Mahmoud; Abdollahi, Hamed; Abdullah, Tala; Abecasis, Goncalo R; Abedalthagafi, Malak; Abul-Husn, Noura S; Acquilini, Donatella; Adams, Emma L; Adamsara, Alireza et al.
DOI: 10.1038/s41586-022-04826-7

A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors.

PMID: 35655320
Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Year: 2022
Reference: J Exp Clin Cancer Res. 2022 Jun 2;41(1):189. doi: 10.1186/s13046-022-02383-5.
Impact factor: 11.161
Publication type: Paper in international publication
Authors: Chan, Stephen L, Schuler, Martin, Kang, Yoon-Koo, Yen, Chia-Jui, Edeline, Julien, Choo, Su Pin, Lin, Chia-Chi, Okusaka, Takuji, Weiss, Karl-Heinz, Macarulla, Teresa et al.
DOI: 10.1186/s13046-022-02383-5

A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors.

PMID: 35655320
Journal: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Year: 2022
Reference: J Exp Clin Cancer Res. 2022 Jun 2;41(1):189. doi: 10.1186/s13046-022-02383-5.
Impact factor:
Publication type: Paper in international publication
Authors: Assenat, Eric; Blanc, Jean-Frederic; Bruix, Jordi; Cattan, Stephane; Chan, Stephen L; Chaudhari, Monica; Choo, Su Pin; Delord, Jean-Pierre; Edeline, Julien; Fan, Jia et al.
DOI: 10.1186/s13046-022-02383-5

A gene expression assay based on chronic lymphocytic leukemia activation in the microenvironment to predict progression.

PMID: 35973197
Journal: Blood Advances
Year: 2022
Reference: Blood Adv. 2022 Nov 8;6(21):5763-5773. doi: 10.1182/bloodadvances.2022007508.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Alcoceba, Miguel; Bobillo, Sabela; Boix, Joan; Bosch, Francesc; Carabia, Julia; Crespo, Marta; Gonzalez, Marcos; Iacoboni, Gloria; Lu, Junyan et al.
DOI: 10.1182/bloodadvances.2022007508

A genome-wide association study of outcome from traumatic brain injury.

PMID: 35301180
Journal: EBioMedicine
Year: 2022
Reference: EBioMedicine. 2022 Mar;77:103933. doi: 10.1016/j.ebiom.2022.103933. Epub 2022 Mar 14.
Impact factor: 8.143
Publication type: Paper in international publication
Authors: Izzy, Saef, Kals, Mart, Kunzmann, Kevin, Parodi, Livia, Radmanesh, Farid, Wilson, Lindsay, Helseth, Eirik, Bellander, Bo-Michael, Belli, Antonio, Benali, Habib et al.
DOI: 10.1016/j.ebiom.2022.103933

A genome-wide association study of outcome from traumatic brain injury.

PMID: 35301180
Journal: EBioMedicine
Year: 2022
Reference: EBioMedicine. 2022 Mar;77:103933. doi: 10.1016/j.ebiom.2022.103933. Epub 2022 Mar 14.
Impact factor:
Publication type: Paper in international publication
Authors: Adeoye, Opeolu; Akerlund, Cecilia; Amrein, Krisztina; Andelic, Nada; Anderson, Christopher D; Andreassen, Lasse; Anke, Audny; Antoni, Anna; Ao, Braden Te; Audibert, Gerard et al.
DOI: 10.1016/j.ebiom.2022.103933

A Global Survey of Physicians Knowledge About Non-alcoholic Fatty Liver Disease.

PMID: 34229038
Journal: Clinical Gastroenterology and Hepatology
Year: 2022
Reference: Clin Gastroenterol Hepatol. 2022 Jun;20(6):e1456-e1468. doi: 10.1016/j.cgh.2021.06.048. Epub 2021 Jul 3.
Impact factor: 11.382
Publication type: Paper in international publication
Authors: Wong, Vincent Wai-Sun, Alswat, Khalid, Chan, Wah-Kheong, Mendez-Sanchez, Nahum, Burra, Patrizia, Bugianesi, Elisabetta, Duseja, Ajay K, George, Jacob, Papatheodoridis, George V, Saeed, Hamid et al.
DOI: 10.1016/j.cgh.2021.06.048

A Global Survey of Physicians Knowledge About Non-alcoholic Fatty Liver Disease.

PMID: 34229038
Journal: Clinical Gastroenterology and Hepatology
Year: 2022
Reference: Clin Gastroenterol Hepatol. 2022 Jun;20(6):e1456-e1468. doi: 10.1016/j.cgh.2021.06.048. Epub 2021 Jul 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alqahtani, Saleh; Alswat, Khalid; Arrese, Marco; Bugianesi, Elisabetta; Burra, Patrizia; Buti, Maria; Castera, Laurent; Chan, Wah-Kheong; Diago, Moises; Duseja, Ajay K et al.
DOI: 10.1016/j.cgh.2021.06.048

A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors.

PMID: 35511749
Journal: MOLECULAR CANCER THERAPEUTICS
Year: 2022
Reference: Mol Cancer Ther. 2022 Jul 5;21(7):1246-1258. doi: 10.1158/1535-7163.MCT-21-0947.
Impact factor: 6.261
Publication type: Paper in international publication
Authors: Salazar-Huayna, Lourdes, Fernandez-Rodriguez, Juana, Creus-Bachiller, Edgar, Zhang, Xiaohu, Martinez-Iniesta, Maria, Ortega-Bertran, Sara, Guha, Rajarshi, Thomas, Craig J, Wallace, Margaret R, Romagosa, Cleofe et al.
DOI: 10.1158/1535-7163.MCT-21-0947

A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors.

PMID: 35511749
Journal: MOLECULAR CANCER THERAPEUTICS
Year: 2022
Reference: Mol Cancer Ther. 2022 Jul 5;21(7):1246-1258. doi: 10.1158/1535-7163.MCT-21-0947.
Impact factor:
Publication type: Paper in international publication
Authors: Blakeley, Jaishri O; Creus-Bachiller, Edgar; Fernandez-Rodriguez, Juana; Ferrer, Marc; Guha, Rajarshi; Lazaro, Conxi; Martinez-Iniesta, Maria; Ortega-Bertran, Sara; Pujana, Miguel Angel; Reilly, Karlyne M et al.
DOI: 10.1158/1535-7163.MCT-21-0947

A large case series of travel-related Mansonella perstans (vector-borne filarial nematode): a TropNet study in Europe.

PMID: 35417002
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2022
Reference: J Travel Med. 2022 Apr 13. pii: 6567953. doi: 10.1093/jtm/taac048.
Impact factor: 8.49
Publication type: Paper in international publication
Authors: Tamarozzi, Francesca, Rodari, Paola, Salas-Coronas, Joaquin, Bottieau, Emmanuel, Salvador, Fernando, Soriano-Perez, Manuel Jesus, Cabeza-Barrera, Maria Isabel, Van Esbroeck, Marjan, Trevino, Begona, Buonfrate, Dora et al.
DOI: 10.1093/jtm/taac048

A large case series of travel-related Mansonella perstans (vector-borne filarial nematode): a TropNet study in Europe.

PMID: 35417002
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2022
Reference: J Travel Med. 2022 Nov 4;29(7). pii: 6567953. doi: 10.1093/jtm/taac048.
Impact factor:
Publication type: Paper in international publication
Authors: Bottieau, Emmanuel; Buonfrate, Dora; Cabeza-Barrera, Maria Isabel; Gobbi, Federico G; Rodari, Paola; Salas-Coronas, Joaquin; Salvador, Fernando; Soriano-Perez, Manuel Jesus; Tamarozzi, Francesca; Trevino, Begona et al.
DOI: 10.1093/jtm/taac048

A method for multiplexed full-length single-molecule sequencing of the human mitochondrial genome.

PMID: 36202811
Journal: Nature Communications
Year: 2022
Reference: Nat Commun. 2022 Oct 6;13(1):5902. doi: 10.1038/s41467-022-33530-3.
Impact factor:
Publication type: Paper in international publication
Authors: Abuli, Anna; Becker, Philipp; Brun-Heath, Isabelle; Canevazzi, Davide; Dabad, Marc; Frias-Lopez, Cristina; Garcia-Arumi, Elena; Gut, Ivo Glynne; Gut, Marta; Heath, Simon Charles et al.
DOI: 10.1038/s41467-022-33530-3

A multicenter, dose-finding, phase 1b study of imatinib in combination with alpelisib as third-line treatment in patients with advanced gastrointestinal stromal tumor.

PMID: 35524239
Journal: BMC CANCER
Year: 2022
Reference: BMC Cancer. 2022 May 6;22(1):511. doi: 10.1186/s12885-022-09610-4.
Impact factor: 4.43
Publication type: Paper in international publication
Authors: Valverde, Claudia, Schoffski, Patrick, Grignani, Giovanni, Reyners, Anna K L, Bauer, Sebastian, Reichardt, Peter, Stark, Daniel, Berhanu, Ghimja, Brandt, Ulrike, Stefanelli, Tommaso et al.
DOI: 10.1186/s12885-022-09610-4

A multicenter, dose-finding, phase 1b study of imatinib in combination with alpelisib as third-line treatment in patients with advanced gastrointestinal stromal tumor.

PMID: 35524239
Journal: BMC CANCER
Year: 2022
Reference: BMC Cancer. 2022 May 6;22(1):511. doi: 10.1186/s12885-022-09610-4.
Impact factor:
Publication type: Paper in international publication
Authors: Bauer, Sebastian; Berhanu, Ghimja; Brandt, Ulrike; Gelderblom, Hans; Grignani, Giovanni; Heinrich, Michael C; Italiano, Antoine; Pantaleo, Maria A; Reichardt, Peter; Reyners, Anna K L et al.
DOI: 10.1186/s12885-022-09610-4