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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort.

PMID: 33900052
Journal: Clinical and Translational Allergy
Year: 2021
Reference: Clin Transl Allergy. 2021 Mar;11(1):e12001. doi: 10.1002/clt2.12001.
Impact factor: 5.871
Publication type: Paper in international publication
Authors: Sastre, Joaquin, Pozo, Victora Del, Valverde, Marcela, Valero, Antonio, Sastre, Beatriz, Rial, Manuel J, Alvarez-Puebla, Maria J, Arismendi, Ebymar, Caballero, Maria L, Canas, Jose A et al.
DOI: 10.1002/clt2.12001

Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future.

PMID: 33399086
Journal: ESMO Open
Year: 2021
Reference: ESMO Open. 2021 Feb;6(1):100024. doi: 10.1016/j.esmoop.2020.100024. Epub 2020 Dec 2.
Impact factor: 6.54
Publication type: Paper in international publication
Authors: Pelosi, G, Hofman, P, Ilie, M, Chamorey, E, Brest, P, Schiappa, R, Nakache, V, Antoine, M, Garcia-Martos, M, Gibault, L et al.
DOI: 10.1016/j.esmoop.2020.100024

Clinical audits in nuclear medicine: wuthering heights.

PMID: 33610494
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2021
Reference: Rev Esp Med Nucl Imagen Mol. 2021 Mar-Apr;40(2):69-71. doi: 10.1016/j.remn.2021.01.004. Epub 2021 Feb 18.
Impact factor: 1.359
Publication type: Editorial in national publication
Authors: Garcia-Burillo, A et al.
DOI: 10.1016/j.remn.2021.01.004

Clinical behavior and outcomes of breast cancer in young women with germline BRCA pathogenic variants.

PMID: 33579978
Journal: npj Breast Cancer
Year: 2021
Reference: NPJ Breast Cancer. 2021 Feb 12;7(1):16. doi: 10.1038/s41523-021-00224-w.
Impact factor: 6.923
Publication type: Paper in international publication
Authors: Rousset-Jablonski, Christine, Lambertini, Matteo, Ceppi, Marcello, Hamy, Anne-Sophie, Caron, Olivier, Poorvu, Philip D, Carrasco, Estela, Grinshpun, Albert, Punie, Kevin, Balmana, Judith et al.
DOI: 10.1038/s41523-021-00224-w

Clinical cases referring to current options and recommendations for the use of thoracic endovascular aortic repair in acute and chronic thoracic aortic disease: an expert consensus document of the European Society for Cardiology (ESC) Working Group of Cardiovascular Surgery, the ESC Working Group on Aorta and Peripheral Vascular Diseases, the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC and the European Association for Cardio-Thoracic Surgery (EACTS).

PMID: 33020812
Journal: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
Year: 2021
Reference: Eur J Cardiothorac Surg. 2021 Jan 4;59(1):74-79. doi: 10.1093/ejcts/ezaa313.
Impact factor: 4.191
Publication type: Paper in international publication
Authors: Czerny, Martin, Pacini, Davide, Aboyans, Victor, Al-Attar, Nawwar, Eggebrecht, Holger, Evangelista, Arturo, Grabenwoger, Martin, Stabile, Eugenio, Kolowca, Maciej, Lescan, Mario et al.
DOI: 10.1093/ejcts/ezaa313

Clinical Challenges in Managing Cervical Intraepithelial Neoplasia 2: A Report From a Cross-sectional Survey.

PMID: 33631780
Journal: Journal of Lower Genital Tract Disease
Year: 2021
Reference: J Low Genit Tract Dis. 2021 Apr 1;25(2):119-125. doi: 10.1097/LGT.0000000000000594.
Impact factor: 1.925
Publication type: Paper in international publication
Authors: Centeno, Cristina, Perez-Benavente, Assumpcio, Gil-Moreno, Antonio, Bradbury, Melissa et al.
DOI: 10.1097/LGT.0000000000000594

Clinical characteristics and factors associated with triple therapy use in newly diagnosed patients with COPD.

PMID: 33753747
Journal: npj Primary Care Respiratory Medicine
Year: 2021
Reference: NPJ Prim Care Respir Med. 2021 Mar 22;31(1):16. doi: 10.1038/s41533-021-00227-x.
Impact factor: 2.871
Publication type: Paper in international publication
Authors: Monteagudo, Monica, Barrecheguren, Miriam, Solntseva, Iryna, Dhalwani, Nafeesa, Booth, Alison, Nunez, Alexa, Lambrelli, Dimitra, Miravitlles, Marc et al.
DOI: 10.1038/s41533-021-00227-x

Clinical Characteristics and Outcomes of Extranodal Stage I Diffuse Large B Cell Lymphoma in The Rituximab-Era.

PMID: 32730585
Journal: BLOOD
Year: 2021
Reference: Blood. 2021 Jan 7;137(1):39-48. doi: 10.1182/blood.2020005112.
Impact factor: 23.629
Publication type: Paper in international publication
Authors: Dogan, Ahmet, Seshan, Venkatraman E, Younes, Anas, Yahalom, Joachim, Zelenetz, Andrew D, von Keudell, Gottfried, Straus, David J, Bobillo, Sabela, Joffe, Erel, Lavery, Jessica A et al.
DOI: 10.1182/blood.2020005112

Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: results from the Brazilian COVID-19 Registry.

PMID: 33444752
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2021
Reference: Int J Infect Dis. 2021 Jun;107:300-310. doi: 10.1016/j.ijid.2021.01.019. Epub 2021 Jan 12.
Impact factor: 3.623
Publication type: Paper in international publication
Authors: Marcolino, Milena S, Ziegelmann, Patricia K, Souza-Silva, Maira V R, do Nascimento, Israel J Borges, Oliveira, Luana M, Monteiro, Luanna S, Sales, Thais L S, Martins, Karina P M P, Etges, Ana Paula B S, Molina, Israel et al.
DOI: 10.1016/j.ijid.2021.01.019

Clinical characteristics in 545 patients with severe asthma on biological treatment during the COVID-19 outbreak.

PMID: 33045398
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2021
Reference: J Allergy Clin Immunol Pract. 2021 Jan;9(1):487-489.e1. doi: 10.1016/j.jaip.2020.09.050. Epub 2020 Oct 9.
Impact factor: 8.861
Publication type: Paper in international publication
Authors: Munoz, Xavier, Rial, Manuel Jorge, Valverde, Marcela, Del Pozo, Victoria, Gonzalez-Barcala, Francisco Javier, Martinez-Rivera, Carlos, Curto, Elena, Quirce, Santiago, Barranco, Pilar, Dominguez-Ortega, Javier et al.
DOI: 10.1016/j.jaip.2020.09.050

Clinical characteristics of COVID-19 in older adults. A retrospective study in long-term nursing homes in Catalonia.

PMID: 34297774
Journal: PLoS One
Year: 2021
Reference: PLoS One. 2021 Jul 23;16(7):e0255141. doi: 10.1371/journal.pone.0255141. eCollection 2021.
Impact factor: 3.24
Publication type: Paper in international publication
Authors: Garcia-Navarro, Jose Augusto, San-Jose, Antonio, Andreu, Antoni L, Campins, Magda, Almirante, Benito, Santaeugenia, Sebastia, Ussi, Anton, Lopez-Segui, Francesc, Meis-Pinheiro, Uxio, Walsh, Sandra et al.
DOI: 10.1371/journal.pone.0255141

Clinical development and evaluation of a VEGF-D assay in plasma from patients with metastatic colorectal cancer in the RAISE study.

PMID: 34229554
Journal: CURRENT MEDICAL RESEARCH AND OPINION
Year: 2021
Reference: Curr Med Res Opin. 2021 Oct;37(10):1769-1778. doi: 10.1080/03007995.2021.1940908. Epub 2021 Jul 28.
Impact factor: 2.58
Publication type: Paper in international publication
Authors: Tabernero, Josep, Van Cutsem, Eric, Robling, Kim R, Abada, Paolo B, Hozak, Rebecca R, Siegel, Robert, Fill, Jeffrey A, Wijayawardana, Sameera, Walgren, Richard A, Giles, Brendan et al.
DOI: 10.1080/03007995.2021.1940908

Clinical effectiveness of olaparib monotherapy in germline BRCA-mutated, HER2-negative metastatic breast cancer in a real-world setting: phase IIIb LUCY interim analysis.

PMID: 34087573
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2021
Reference: Eur J Cancer. 2021 Jul;152:68-77. doi: 10.1016/j.ejca.2021.03.029. Epub 2021 Jun 1.
Impact factor: 9.162
Publication type: Paper in international publication
Authors: Bordonaro, Roberto, Levy, Christelle, Lortholary, Alain, Mailliez, Audrey, Medioni, Jacques, Patsouris, Anne, Spaeth, Dominique, Teixeira, Luis, Tennevet, Isabelle, Villanueva, Cristian et al.
DOI: 10.1016/j.ejca.2021.03.029

Clinical effects of intrathecal administration of expanded Wharton jelly mesenchymal stromal cells in patients with chronic complete spinal cord injury: a randomized controlled study.

PMID: 32981857
Journal: CYTOTHERAPY
Year: 2021
Reference: Cytotherapy. 2021 Feb;23(2):146-156. doi: 10.1016/j.jcyt.2020.08.008. Epub 2020 Sep 25.
Impact factor: 5.414
Publication type: Paper in international publication
Authors: Albu, Sergiu, Kumru, Hatice, Coll, Ruth, Vives, Joaquim, Valles, Margarita, Benito-Penalva, Jesus, Rodriguez, Luciano, Codinach, Margarita, Hernandez, Joaquim, Navarro, Xavier et al.
DOI: 10.1016/j.jcyt.2020.08.008

Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure.

PMID: 32781201
Journal: JOURNAL OF HEPATOLOGY
Year: 2021
Reference: J Hepatol. 2021 Feb;74(2):330-339. doi: 10.1016/j.jhep.2020.07.046. Epub 2020 Aug 8.
Impact factor: 25.083
Publication type: Paper in international publication
Authors: Verhelst, Xavier, Wong, Florence, Piano, Salvatore, Singh, Virendra, Bartoletti, Michele, Maiwall, Rakhi, Alessandria, Carlo, Fernandez, Javier, Soares, Elza Cotrim, Kim, Dong Joon et al.
DOI: 10.1016/j.jhep.2020.07.046

Clinical features and health-related quality of life in adult patients with mucopolysaccharidosis IVA: the Spanish experience.

PMID: 34732228
Journal: Orphanet Journal of Rare Diseases
Year: 2021
Reference: Orphanet J Rare Dis. 2021 Nov 3;16(1):464. doi: 10.1186/s13023-021-02074-y.
Impact factor: 4.123
Publication type: Paper in international publication
Authors: Quijada-Fraile, Pilar, Arranz Canales, Elena, Martin-Hernandez, Elena, Ballesta-Martinez, Maria Juliana, Guillen-Navarro, Encarna, Pintos-Morell, Guillem, Molto-Abad, Marc, Moreno-Martinez, David, Garcia Morillo, Salvador, Blasco-Alonso, Javier et al.
DOI: 10.1186/s13023-021-02074-y

Clinical Features and Outcomes of Pregnancy-Related Acute Aortic Dissection.

PMID: 33052376
Journal: JAMA Cardiology
Year: 2021
Reference: JAMA Cardiol. 2021 Jan 1;6(1):58-66. doi: 10.1001/jamacardio.2020.4876.
Impact factor: 14.676
Publication type: Paper in international publication
Authors: Braverman, Alan C, Mittauer, Eric, Harris, Kevin M, Evangelista, Arturo, Pyeritz, Reed E, Brinster, Derek, Conklin, Lori, Suzuki, Toru, Fanola, Christina, Chen, Edward et al.
DOI: 10.1001/jamacardio.2020.4876

Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study.

PMID: 34189163
Journal: Open Forum Infectious Diseases
Year: 2021
Reference: Open Forum Infect Dis. 2021 Mar 29;8(6):ofab163. doi: 10.1093/ofid/ofab163. eCollection 2021 Jun.
Impact factor: 3.835
Publication type: Paper in international publication
Authors: Goenaga, Miguel Angel, Escrihuela-Vidal, Francesc, Lopez-Cortes, Luis Eduardo, Escola-Verge, Laura, De Alarcon Gonzalez, Aristides, Cuervo, Guillermo, Sanchez-Porto, Antonio, Fernandez-Hidalgo, Nuria, Luque, Rafael, Montejo, Miguel et al.
DOI: 10.1093/ofid/ofab163

Clinical Impact of Crossover Techniques for Primary Access Hemostasis in Transfemoral Transcatheter Aortic Valve Replacement Procedures.

PMID: 33600353
Journal: JOURNAL OF INVASIVE CARDIOLOGY
Year: 2021
Reference: J Invasive Cardiol. 2021 Apr;33(4):E302-E311. Epub 2021 Feb 18.
Impact factor: 2.022
Publication type: Paper in international publication
Authors: Colombo, Antonio, Munoz Garcia, Erika, Vera Urquiza, Rafael, Jimenez-Quevedo, Pilar, Pascual, Isaac, Garcia Del Blanco, Bruno, Sabate, Manel, Mohammadi, Siamak, Freitas-Ferraz, Afonso B, Muntane-Carol, Guillem et al.
DOI:

Clinical Impact of Medical Therapy Versus Revascularization in Patients With Chronic Coronary Total Occlusions.

PMID: 33385980
Journal: JOURNAL OF INVASIVE CARDIOLOGY
Year: 2021
Reference: J Invasive Cardiol. 2021 Jan;33(1):E2-E8.
Impact factor: 2.022
Publication type: Paper in international publication
Authors: Cepas-Guillen, Pedro, Ferreira-Gonzalez, Ignacio, Freixa, Xavier, Regueiro, Ander, Brugaletta, Salvatore, Sabate, Manel, Martin-Yuste, Victoria, Flores-Umanzor, Eduardo, Alvarez-Contreras, Luis et al.
DOI:

Clinical impact of pre-surgery circulating tumor DNA after total neoadjuvant treatment in locally advanced rectal cancer: a biomarker study from the GEMCAD1402 Trial.

PMID: 33727257
Journal: CLINICAL CANCER RESEARCH
Year: 2021
Reference: Clin Cancer Res. 2021 May 15;27(10):2890-2898. doi: 10.1158/1078-0432.CCR-20-4769. Epub 2021 Mar 16.
Impact factor: 12.531
Publication type: Paper in international publication
Authors: Gallego-Plazas, Javier, Vera, Ruth, Salud, Antonieta, MArtin Richard, Marta, Nogue, Miguel, Cillan, Elena, Maurel, Joan, Faull, Iris, Raymond, Victoria M, Fernandez-Martos, Carlos et al.
DOI: 10.1158/1078-0432.CCR-20-4769

Clinical improvement within 24 hours from mechanical thrombectomy as a predictor of long-term functional outcome in a multicenter population-based cohort of patients with ischemic stroke.

PMID: 32461229
Journal: Journal of NeuroInterventional Surgery
Year: 2021
Reference: J Neurointerv Surg. 2021 Feb;13(2):119-123. doi: 10.1136/neurintsurg-2020-015934. Epub 2020 May 27.
Impact factor: 5.836
Publication type: Paper in international publication
Authors: Rudilosso, Salvatore, Laredo, Carlos, Amaro, Sergio, Renu, Arturo, Llull, Laura, Obach, Victor, Moreno, Javier, Ribo, Marc, Abilleira, Sonia, Cardona, Pedro et al.
DOI: 10.1136/neurintsurg-2020-015934

Clinical management of cUTI, cIAI, and HABP/VABP attributable to carbapenem-resistant Gram-negative infections in Spain.

PMID: 34806858
Journal: Revista Espanola de Quimioterapia
Year: 2021
Reference: Rev Esp Quimioter. 2021 Nov 22. doi: 10.37201/req/096.2021.
Impact factor: 1.553
Publication type: Paper in international publication
Authors: Lara, N, McCann, E, Fenoll, R, Gomez-Ulloa, D, Lozano, V, Lopez, D, Ferrer, R, Farinas, M C, Maseda, E, Salavert, M et al.
DOI: 10.37201/req/096.2021

Clinical outcome of COVID-19 in patients with adult congenital heart disease.

PMID: 33685931
Journal: HEART
Year: 2021
Reference: Heart. 2021 Mar 8. pii: heartjnl-2020-318467. doi: 10.1136/heartjnl-2020-318467.
Impact factor: 5.994
Publication type: Paper in international publication
Authors: Schwerzmann, Markus, Ruperti-Repilado, Francisco Javier, Baumgartner, Helmut, Bouma, Berto, Bouchardy, Judith, Budts, Werner, Campens, Laurence, Chessa, Massimo, Del Cerro Marin, Maria Jesus, Gabriel, Harald et al.
DOI: 10.1136/heartjnl-2020-318467