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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Empirical antibiotic therapy improves outcomes in mechanically ventilated patients with COVID-19: An emulated targeted trial within a prospective, multicentre cohort study.

PMID: 39814268
Journal: JOURNAL OF INFECTION
Year: 2025
Reference: J Infect. 2025 Jan 13:106411. doi: 10.1016/j.jinf.2025.106411.
Impact factor:
Publication type: Paper in international publication
Authors: Almansa, Raquel; Alvarez-Napagao, Sergio; Amaya-Villar, Rosario; Anon, Jose M; Barbe, Ferran; Barbera, Carme; Barberan, Jose; Barral-Segade, Patricia; Blandino-Ortiz, Aaron; Bustamante-Munguira, Elena et al.
DOI: 10.1016/j.jinf.2025.106411

ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancer.

PMID: 39983444
Journal: LUNG CANCER
Year: 2025
Reference: Lung Cancer. 2025 Feb 7;201:108105. doi: 10.1016/j.lungcan.2025.108105.
Impact factor:
Publication type: Paper in international publication
Authors: Alfon, Jose; Bosch-Barrera, Joaquim; Cortal, Marc; Domenech, Carles; Estevez-Garcia, Purificacion; Fierro-Duran, Gemma; Gascon, Pere; Lizcano, Jose M; Martin-Martorell, Paloma; Moran, Teresa et al.
DOI: 10.1016/j.lungcan.2025.108105

Endovascular Treatment for Stroke Due to Occlusion of Medium or Distal Vessels.

PMID: 39908430
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2025
Reference: N Engl J Med. 2025 Feb 5. doi: 10.1056/NEJMoa2408954.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Angelika; Amaro, Sergio; Arenillas, Juan F; Balmer, Luzia; Bellante, Flavio; Bolognese, Manuel; Brehm, Alex; Buhk, Jan-Hendrik; Castano, Carlos; Coutinho, Jonathan M et al.
DOI: 10.1056/NEJMoa2408954

European Guideline on Chronic Nausea and Vomiting-A UEG and ESNM Consensus for Clinical Management.

PMID: 39754724
Journal: United European Gastroenterology Journal
Year: 2025
Reference: United European Gastroenterol J. 2025 Jan 4. doi: 10.1002/ueg2.12711.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Ariadna; Alcala-Gonzalez, Luis; Aziz, Imran; Barba, Elizabeth; Bonaz, Bruno; Carbone, Florencia; Corsetti, Maura; De Giorgio, Roberto; Drewes, Asbjorn Mohr; Dumitrascu, Dan et al.
DOI: 10.1002/ueg2.12711

Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study.

PMID: 39857074
Journal: Diagnostics
Year: 2025
Reference: Diagnostics (Basel). 2025 Jan 15;15(2):189. doi: 10.3390/diagnostics15020189.
Impact factor:
Publication type: Paper in international publication
Authors: Amigo, Judit; Calveiro, Marta; Carreras, Elena; Casellas, Alba; Del Barco, Ester; Ferrer, Roser; Goya, Maria; Maroto, Anna; Marti, Laia; Martinez, Cristina et al.
DOI: 10.3390/diagnostics15020189

Evaluation of dried blood spot sampling for real-time PCR malaria diagnostics in a rural setting in Angola.

PMID: 39915805
Journal: Parasites & Vectors
Year: 2025
Reference: Parasit Vectors. 2025 Feb 7;18(1):44. doi: 10.1186/s13071-025-06685-3.
Impact factor:
Publication type: Paper in international publication
Authors: Aixut, Sandra; Aznar, Maria Luisa; Crego-Vicente, Beatriz; Febrer-Sendra, Begona; Fernandez-Soto, Pedro; Goterris, Lidia; Martinez-Camprecios, Joan; Martinez-Vallejo, Patricia; Maturana, Carles Rubio; Mediavilla, Alejandro et al.
DOI: 10.1186/s13071-025-06685-3

Evaluation of enzyme activity predictions for variants of unknown significance in Arylsulfatase A.

PMID: 40055237
Journal: HUMAN GENETICS
Year: 2025
Reference: Hum Genet. 2025 Mar 8. doi: 10.1007/s00439-025-02731-3.
Impact factor:
Publication type: Paper in international publication
Authors: Acuna-Hidalgo, Rocio; Astore, Courtney; Babbi, Giulia; Bakolitsa, Constantina; Barron, Laura T Jimenez; Berardelli, Silvia; Brenner, Steven E; Calici, Sumeyra Zeynep; Casadio, Rita; Cedillo, Luis R et al.
DOI: 10.1007/s00439-025-02731-3

Evaluation of magnetic resonance spectroscopy total sodium concentration measures, and associations with microstructure and physical impairment in cervical myelopathy.

PMID: 40016502
Journal: Scientific Reports
Year: 2025
Reference: Sci Rep. 2025 Feb 27;15(1):7014. doi: 10.1038/s41598-025-91658-w.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Ahmad, Selma; Bianchi, Alessia; Choi, David; Grussu, Francesco; Kanber, Baris; Panicker, Jalesh N; Prados, Ferran; Russo, Antonino; Russo, Vittorio; Solanky, Bhavana S et al.
DOI: 10.1038/s41598-025-91658-w

Ex vivo T-lymphopoiesis assays assisting corrective treatment choice for genetically undefined T-lymphocytopaenia.

PMID: 39965724
Journal: CLINICAL IMMUNOLOGY
Year: 2025
Reference: Clin Immunol. 2025 Feb 16:110453. doi: 10.1016/j.clim.2025.110453.
Impact factor:
Publication type: Paper in international publication
Authors: Adams, Stuart; Andre, Isabelle; Awuah, Arnold; Bernard, Fanette; Boztug, Kaan; Buckland, Matthew; Cole, Theresa; Corredera, Marta Martin; Davies, E Graham; De Braem, Victoria Bordon Cueto et al.
DOI: 10.1016/j.clim.2025.110453

Explaining cognitive function in multiple sclerosis through networks of grey and white matter features: a joint independent component analysis.

PMID: 39812878
Journal: JOURNAL OF NEUROLOGY
Year: 2025
Reference: J Neurol. 2025 Jan 15;272(2):142. doi: 10.1007/s00415-024-12795-2.
Impact factor:
Publication type: Paper in international publication
Authors: Calhoun, Vince D; Chard, Declan T; Eierud, Cyrus; Eshaghi, Arman; Jolly, Amy; Kanber, Baris; Lageman, Senne B; Prados, Ferran; Sahi, Nitin; Schoonheim, Menno M et al.
DOI: 10.1007/s00415-024-12795-2

Exposomal determinants of non-genetic plasticity in tumor initiation.

PMID: 40023688
Journal: Trends in Cancer
Year: 2025
Reference: Trends Cancer. 2025 Feb 28:S2405-8033(25)00011-1. doi: 10.1016/j.trecan.2025.01.010.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Curbelo, Direna; Carra, Davide; Maas, Silvana C E; Seoane, Jose A et al.
DOI: 10.1016/j.trecan.2025.01.010

Extracellular Vesicles as Tools for Crossing the Blood-Brain Barrier to Treat Lysosomal Storage Diseases.

PMID: 39860010
Journal: Life-Basel
Year: 2025
Reference: Life (Basel). 2025 Jan 9;15(1):70. doi: 10.3390/life15010070.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Ibane; Del Toro, Mireia; Lerussi, Giovanni; Molto-Abad, Marc; Pintos-Morell, Guillem; Seras-Franzoso, Joaquin; Villagrasa-Araya, Veronica et al.
DOI: 10.3390/life15010070

Extracorporeal Life Support Organization 2024 Guideline for Early Rehabilitation or Mobilization of Adult Patients on Extracorporeal Membrane Oxygenation.

PMID: 39883803
Journal: ASAIO JOURNAL
Year: 2025
Reference: ASAIO J. 2025 Jan 28. doi: 10.1097/MAT.0000000000002375.
Impact factor:
Publication type: Paper in international publication
Authors: Brodie, Daniel; Broman, Lars; Cruz, Sherene; Diaz, Rodrigo; Herr, Daniel; Hodgson, Carol; O'Neil, Erika; Peek, Giles; Ramanan, Raj; Ramanathan, Kollengode et al.
DOI: 10.1097/MAT.0000000000002375

First-in-Human Phase 1 study of a CD16A bispecific innate cell engager, AFM24, targeting EGFR-expressing solid tumors.

PMID: 39846810
Journal: CLINICAL CANCER RESEARCH
Year: 2025
Reference: Clin Cancer Res. 2025 Jan 23. doi: 10.1158/1078-0432.CCR-24-1991.
Impact factor:
Publication type: Paper in international publication
Authors: Berrien-Elliott, Melissa M; El-Khoueiry, Anthony; Emig, Michael; Fehniger, Todd A; Foster, Mark; Garralda, Elena; Hintzen, Gabriele; Koch, Joachim; Kohlhas, Laura; Livings, Claire et al.
DOI: 10.1158/1078-0432.CCR-24-1991

Fluid fluctuations assessed with artificial intelligence during the maintenance phase impact anti-vascular endothelial growth factor visual outcomes in a multicentre, routine clinical care national age-related macular degeneration database.

PMID: 39848699
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2025
Reference: Br J Ophthalmol. 2025 Jan 23:bjo-2024-325615. doi: 10.1136/bjo-2024-325615.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, Maximino; Alforja, Socorro; Apostolopoulos, Stefanos; Arruabarrena, Carolina; Bernal-Morales, Carolina; Broc, Laura; Casaroli-Marano, Ricardo P; Ciller, Carlos; De Zanet, Sandro; Escobar-Barranco, Jose Juan et al.
DOI: 10.1136/bjo-2024-325615

Forever young.

PMID: 39784932
Journal: Multiple Sclerosis Journal
Year: 2025
Reference: Mult Scler. 2025 Jan;31(1):3-5. doi: 10.1177/13524585241311154.
Impact factor:
Publication type: Editorail in international publication
Authors: Brownlee, Wallace; Chard, Declan T; Graves, Jennifer; Hedstrom, Anna Karin; Kim, Ho Jin; Moccia, Marcello; Ontaneda, Daniel; Rocca, Maria A; Sastre-Garriga, Jaume; Thompson, Alan J et al.
DOI: 10.1177/13524585241311154

Gene therapy rescues brain edema and motor function in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts.

PMID: 40051162
Journal: MOLECULAR THERAPY
Year: 2025
Reference: Mol Ther. 2025 Mar 5:S1525-0016(25)00173-X. doi: 10.1016/j.ymthe.2025.02.046.
Impact factor:
Publication type: Paper in international publication
Authors: Bosch, Assumpcio; Brao, Alejandro; Chillon, Miguel; Del Rey, Javier; Estevez, Raul; Lope-Piedrafita, Silvia; Nunes, Virginia; Prat, Esther; Rodriguez, Irina; Sanchez, Angela et al.
DOI: 10.1016/j.ymthe.2025.02.046

Genetic subtyping by Whole Exome Sequencing across Diffuse Large B Cell Lymphoma and Plasmablastic Lymphoma.

PMID: 40067847
Journal: PLoS One
Year: 2025
Reference: PLoS One. 2025 Mar 11;20(3):e0318689. doi: 10.1371/journal.pone.0318689. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Arribas, Patricia; Carrillo, Estrella; de Oteyza, Jaime Perez; Garcia-Sancho, Alejandro Martin; Gonzalez, Sonia; Gonzalez-Barca, Eva; Grande, Carlos; Gutierrez, Antonio; Gutierrez, Norma et al.
DOI: 10.1371/journal.pone.0318689

Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses.

PMID: 39825153
Journal: NATURE MEDICINE
Year: 2025
Reference: Nat Med. 2025 Jan 17. doi: 10.1038/s41591-024-03420-w.
Impact factor:
Publication type: Paper in international publication
Authors: Aretz, Stefan; Baets, Jonathan; Beltran, Sergi; Benetti, Elisa; Brookes, Anthony J; Brunner, Han G; Bullich, Gemma; Chinnery, Patrick F; Clayton-Smith, Jill; Cohen, Enzo et al.
DOI: 10.1038/s41591-024-03420-w

Genomics yields biological and phenotypic insights into bipolar disorder.

PMID: 39843750
Journal: NATURE
Year: 2025
Reference: Nature. 2025 Jan 22. doi: 10.1038/s41586-024-08468-9.
Impact factor:
Publication type: Paper in international publication
Authors: Adolfsson, Rolf; Adorjan, Kristina; Agerbo, Esben; Albani, Diego; Alda, Martin; Alemany, Silvia; Alfredsson, Lars; Alliey-Rodriguez, Ney; Als, Thomas D; Andlauer, Till F M et al.
DOI: 10.1038/s41586-024-08468-9

Giancarlo COMI (1947-2024).

PMID: 39931971
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2025
Reference: Eur J Neurol. 2025 Feb;32(2):e70078. doi: 10.1111/ene.70078.
Impact factor:
Publication type: Paper in international publication
Authors: Edan, Gilles; Hartung, Hans-Peter; Montalban, Xavier et al.
DOI: 10.1111/ene.70078

Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study.

PMID: 40058397
Journal: Lancet Gastroenterology & Hepatology
Year: 2025
Reference: Lancet Gastroenterol Hepatol. 2025 Mar 6:S2468-1253(25)00006-8. doi: 10.1016/S2468-1253(25)00006-8.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelkader, Nadia Abdelaaty; Alessandria, Carlo; Allegretti, Andrew S; Angeli, Paolo; Arab, Juan Pablo; Asrani, Sumeet K; Balcar, Lorenz; Barone, Anna; Bruns, Tony; Cabrera, Maria Cecilia et al.
DOI: 10.1016/S2468-1253(25)00006-8

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia and small lymphocytic lymphoma from Chronic Lymphocytic Leukemia Spanish Group (GELLC).

PMID: 39799061
Journal: MEDICINA CLINICA
Year: 2025
Reference: Med Clin (Barc). 2025 Jan 10:S0025-7753(24)00696-1. doi: 10.1016/j.medcli.2024.10.018.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Alcoceba, Miguel; Bosch, Francesc; Crespo, Marta; de la Serna, Javier; Delgado, Julio; Espinet, Blanca; Gonzalez, Marcos; Hernandez-Rivas, Jose-Angel; Loscertales, Javier et al.
DOI: 10.1016/j.medcli.2024.10.018

Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses.

PMID: 39937896
Journal: Science Advances
Year: 2025
Reference: Sci Adv. 2025 Feb 14;11(7):eado9455. doi: 10.1126/sciadv.ado9455. Epub 2025 Feb 12.
Impact factor:
Publication type: Paper in international publication
Authors: Britton, Graham J; Canales-Herrerias, Pablo; Cerutti, Andrea; Clemente, Jose C; Cunningham-Rundles, Charlotte; Dieli-Crimi, Romina; Faith, Jeremiah J; Garcia Prat, Marina; Grasset, Emilie K; Gutzeit, Cindy et al.
DOI: 10.1126/sciadv.ado9455

Publications