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The science produced by our scientists is very important. In 2024, 1,501 papers were published in scientific journals with an average impact factor of over 7.13 points.

Evaluation of magnetic resonance spectroscopy total sodium concentration measures, and associations with microstructure and physical impairment in cervical myelopathy.

PMID: 40016502
Journal: Scientific Reports
Year: 2025
Reference: Sci Rep. 2025 Feb 27;15(1):7014. doi: 10.1038/s41598-025-91658-w.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Ahmad, Selma; Bianchi, Alessia; Choi, David; Grussu, Francesco; Kanber, Baris; Panicker, Jalesh N; Prados, Ferran; Russo, Antonino; Russo, Vittorio; Solanky, Bhavana S et al.
DOI: 10.1038/s41598-025-91658-w

Ex vivo T-lymphopoiesis assays assisting corrective treatment choice for genetically undefined T-lymphocytopaenia.

PMID: 39965724
Journal: CLINICAL IMMUNOLOGY
Year: 2025
Reference: Clin Immunol. 2025 Feb 16:110453. doi: 10.1016/j.clim.2025.110453.
Impact factor:
Publication type: Paper in international publication
Authors: Adams, Stuart; Andre, Isabelle; Awuah, Arnold; Bernard, Fanette; Boztug, Kaan; Buckland, Matthew; Cole, Theresa; Corredera, Marta Martin; Davies, E Graham; De Braem, Victoria Bordon Cueto et al.
DOI: 10.1016/j.clim.2025.110453

Expanding the SIAH1-Associated Phenotypic Spectrum: Insights From Loss-of-Function Variants.

PMID: 40156476
Journal: AMERICAN JOURNAL OF MEDICAL GENETICS PART A
Year: 2025
Reference: Am J Med Genet A. 2025 Mar 29:e64048. doi: 10.1002/ajmg.a.64048.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, Paula Fernandez; Douiev, Liza; Frank, Marika; Hanington, Lucy; Harel, Tamar; Hoffman, Trevor L; Irons, Mira B; Kim, Jenny; Kumar, Akash; Lasa-Aranzasti, Amaia et al.
DOI: 10.1002/ajmg.a.64048

Explaining cognitive function in multiple sclerosis through networks of grey and white matter features: a joint independent component analysis.

PMID: 39812878
Journal: JOURNAL OF NEUROLOGY
Year: 2025
Reference: J Neurol. 2025 Jan 15;272(2):142. doi: 10.1007/s00415-024-12795-2.
Impact factor:
Publication type: Paper in international publication
Authors: Calhoun, Vince D; Chard, Declan T; Eierud, Cyrus; Eshaghi, Arman; Jolly, Amy; Kanber, Baris; Lageman, Senne B; Prados, Ferran; Sahi, Nitin; Schoonheim, Menno M et al.
DOI: 10.1007/s00415-024-12795-2

Exploring the Capacity of Large Language Models to Assess the Chronic Pain Experience: Algorithm Development and Validation.

PMID: 40163858
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2025
Reference: J Med Internet Res. 2025 Mar 31;27:e65903. doi: 10.2196/65903.
Impact factor:
Publication type: Paper in international publication
Authors: Albajes, Klara; Amidei, Jacopo; Ferreira De Sa, Jose Gregorio; Kaltenbrunner, Andreas; Nieto, Ruben; Serrat, Mayte et al.
DOI: 10.2196/65903

Exposomal determinants of non-genetic plasticity in tumor initiation.

PMID: 40023688
Journal: Trends in Cancer
Year: 2025
Reference: Trends Cancer. 2025 Feb 28:S2405-8033(25)00011-1. doi: 10.1016/j.trecan.2025.01.010.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Curbelo, Direna; Carra, Davide; Maas, Silvana C E; Seoane, Jose A et al.
DOI: 10.1016/j.trecan.2025.01.010

Extracellular Vesicles as Tools for Crossing the Blood-Brain Barrier to Treat Lysosomal Storage Diseases.

PMID: 39860010
Journal: Life-Basel
Year: 2025
Reference: Life (Basel). 2025 Jan 9;15(1):70. doi: 10.3390/life15010070.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Ibane; Del Toro, Mireia; Lerussi, Giovanni; Molto-Abad, Marc; Pintos-Morell, Guillem; Seras-Franzoso, Joaquin; Villagrasa-Araya, Veronica et al.
DOI: 10.3390/life15010070

Extracorporeal Life Support Organization 2024 Guideline for Early Rehabilitation or Mobilization of Adult Patients on Extracorporeal Membrane Oxygenation.

PMID: 39883803
Journal: ASAIO JOURNAL
Year: 2025
Reference: ASAIO J. 2025 Jan 28. doi: 10.1097/MAT.0000000000002375.
Impact factor:
Publication type: Paper in international publication
Authors: Brodie, Daniel; Broman, Lars; Cruz, Sherene; Diaz, Rodrigo; Herr, Daniel; Hodgson, Carol; O'Neil, Erika; Peek, Giles; Ramanan, Raj; Ramanathan, Kollengode et al.
DOI: 10.1097/MAT.0000000000002375

First prospective, single-arm, multicenter study to evaluate safety and efficacy of the overall thrombectomy system -iNedit, iNdeep, and iNtercept- for acute ischemic stroke. Rationale beyond the study.

PMID: 40134692
Journal: Frontiers in Neurology
Year: 2025
Reference: Front Neurol. 2025 Mar 5;16:1537008. doi: 10.3389/fneur.2025.1537008. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Domingo-Rodriguez, Laura; Duocastella, Lluis; Duran, Marta; Gramegna, Laura Ludovica; Macho, Juan; Pich, Sara; San Roman, Luis et al.
DOI: 10.3389/fneur.2025.1537008

First-in-Human Phase 1 study of a CD16A bispecific innate cell engager, AFM24, targeting EGFR-expressing solid tumors.

PMID: 39846810
Journal: CLINICAL CANCER RESEARCH
Year: 2025
Reference: Clin Cancer Res. 2025 Jan 23. doi: 10.1158/1078-0432.CCR-24-1991.
Impact factor:
Publication type: Paper in international publication
Authors: Berrien-Elliott, Melissa M; El-Khoueiry, Anthony; Emig, Michael; Fehniger, Todd A; Foster, Mark; Garralda, Elena; Hintzen, Gabriele; Koch, Joachim; Kohlhas, Laura; Livings, Claire et al.
DOI: 10.1158/1078-0432.CCR-24-1991

Fluid fluctuations assessed with artificial intelligence during the maintenance phase impact anti-vascular endothelial growth factor visual outcomes in a multicentre, routine clinical care national age-related macular degeneration database.

PMID: 39848699
Journal: BRITISH JOURNAL OF OPHTHALMOLOGY
Year: 2025
Reference: Br J Ophthalmol. 2025 Jan 23:bjo-2024-325615. doi: 10.1136/bjo-2024-325615.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, Maximino; Alforja, Socorro; Apostolopoulos, Stefanos; Arruabarrena, Carolina; Bernal-Morales, Carolina; Broc, Laura; Casaroli-Marano, Ricardo P; Ciller, Carlos; De Zanet, Sandro; Escobar-Barranco, Jose Juan et al.
DOI: 10.1136/bjo-2024-325615

Forever young.

PMID: 39784932
Journal: Multiple Sclerosis Journal
Year: 2025
Reference: Mult Scler. 2025 Jan;31(1):3-5. doi: 10.1177/13524585241311154.
Impact factor:
Publication type: Editorail in international publication
Authors: Brownlee, Wallace; Chard, Declan T; Graves, Jennifer; Hedstrom, Anna Karin; Kim, Ho Jin; Moccia, Marcello; Ontaneda, Daniel; Rocca, Maria A; Sastre-Garriga, Jaume; Thompson, Alan J et al.
DOI: 10.1177/13524585241311154

Gender differences in ADHD and impulsivity among alcohol or alcohol- and cocaine-dependent patients.

PMID: 40084061
Journal: Frontiers in Psychiatry
Year: 2025
Reference: Front Psychiatry. 2025 Feb 27;16:1446970. doi: 10.3389/fpsyt.2025.1446970. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Lourdes; Alvarez-Navares, Ana; Buch-Vicente, Barbara; Garcia-Ullan, LLanyra; Gonzalez-Bolanos, Kristofer Ramon; Grau-Lopez, Lara; Palma-Alvarez, Raul Felipe; Perez, Jesus; Remon-Gallo, Diego; Roncero, Carlos et al.
DOI: 10.3389/fpsyt.2025.1446970

Gene therapy rescues brain edema and motor function in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts.

PMID: 40051162
Journal: MOLECULAR THERAPY
Year: 2025
Reference: Mol Ther. 2025 Mar 5:S1525-0016(25)00173-X. doi: 10.1016/j.ymthe.2025.02.046.
Impact factor:
Publication type: Paper in international publication
Authors: Bosch, Assumpcio; Brao, Alejandro; Chillon, Miguel; Del Rey, Javier; Estevez, Raul; Lope-Piedrafita, Silvia; Nunes, Virginia; Prat, Esther; Rodriguez, Irina; Sanchez, Angela et al.
DOI: 10.1016/j.ymthe.2025.02.046

Genetic subtyping by Whole Exome Sequencing across Diffuse Large B Cell Lymphoma and Plasmablastic Lymphoma.

PMID: 40067847
Journal: PLoS One
Year: 2025
Reference: PLoS One. 2025 Mar 11;20(3):e0318689. doi: 10.1371/journal.pone.0318689. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Arribas, Patricia; Carrillo, Estrella; de Oteyza, Jaime Perez; Garcia-Sancho, Alejandro Martin; Gonzalez, Sonia; Gonzalez-Barca, Eva; Grande, Carlos; Gutierrez, Antonio; Gutierrez, Norma et al.
DOI: 10.1371/journal.pone.0318689

Genomic characterisation of invasive Neisseria meningitidis in Spain (2011/12-2022/23): Expansion of clonal complex 213 and the potential threat to 4CMenB vaccine strain coverage.

PMID: 40105365
Journal: Emerging Microbes & Infections
Year: 2025
Reference: Emerg Microbes Infect. 2025 Mar 19:2482696. doi: 10.1080/22221751.2025.2482696.
Impact factor:
Publication type: Paper in international publication
Authors: Angeles Orellana, M; Belles-Belles, Alba; Camara, Jordi; Cercenado, Emilia; de Gopegui, Enrique Ruiz; de la Cruz, Daniel Navarro; Dolores Quesada, M; Galan-Ladero, M A; Gonzalez-Lopez, Juan Jose; Larrosa, Nieves et al.
DOI: 10.1080/22221751.2025.2482696

Genomic reanalysis of a pan-European rare-disease resource yields new diagnoses.

PMID: 39825153
Journal: NATURE MEDICINE
Year: 2025
Reference: Nat Med. 2025 Jan 17. doi: 10.1038/s41591-024-03420-w.
Impact factor:
Publication type: Paper in international publication
Authors: Aretz, Stefan; Baets, Jonathan; Beltran, Sergi; Benetti, Elisa; Brookes, Anthony J; Brunner, Han G; Bullich, Gemma; Chinnery, Patrick F; Clayton-Smith, Jill; Cohen, Enzo et al.
DOI: 10.1038/s41591-024-03420-w

Genomics yields biological and phenotypic insights into bipolar disorder.

PMID: 39843750
Journal: NATURE
Year: 2025
Reference: Nature. 2025 Jan 22. doi: 10.1038/s41586-024-08468-9.
Impact factor:
Publication type: Paper in international publication
Authors: Adolfsson, Rolf; Adorjan, Kristina; Agerbo, Esben; Albani, Diego; Alda, Martin; Alemany, Silvia; Alfredsson, Lars; Alliey-Rodriguez, Ney; Als, Thomas D; Andlauer, Till F M et al.
DOI: 10.1038/s41586-024-08468-9

Giancarlo COMI (1947-2024).

PMID: 39931971
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2025
Reference: Eur J Neurol. 2025 Feb;32(2):e70078. doi: 10.1111/ene.70078.
Impact factor:
Publication type: Paper in international publication
Authors: Edan, Gilles; Hartung, Hans-Peter; Montalban, Xavier et al.
DOI: 10.1111/ene.70078

Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study.

PMID: 40058397
Journal: Lancet Gastroenterology & Hepatology
Year: 2025
Reference: Lancet Gastroenterol Hepatol. 2025 Mar 6:S2468-1253(25)00006-8. doi: 10.1016/S2468-1253(25)00006-8.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelkader, Nadia Abdelaaty; Alessandria, Carlo; Allegretti, Andrew S; Angeli, Paolo; Arab, Juan Pablo; Asrani, Sumeet K; Balcar, Lorenz; Barone, Anna; Bruns, Tony; Cabrera, Maria Cecilia et al.
DOI: 10.1016/S2468-1253(25)00006-8

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia and small lymphocytic lymphoma from Chronic Lymphocytic Leukemia Spanish Group (GELLC).

PMID: 39799061
Journal: MEDICINA CLINICA
Year: 2025
Reference: Med Clin (Barc). 2025 Jan 10:S0025-7753(24)00696-1. doi: 10.1016/j.medcli.2024.10.018.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Alcoceba, Miguel; Bosch, Francesc; Crespo, Marta; de la Serna, Javier; Delgado, Julio; Espinet, Blanca; Gonzalez, Marcos; Hernandez-Rivas, Jose-Angel; Loscertales, Javier et al.
DOI: 10.1016/j.medcli.2024.10.018

Guidelines of the International Headache Society for Real-World Evidence studies in migraine and cluster headache.

PMID: 40095946
Journal: CEPHALALGIA
Year: 2025
Reference: Cephalalgia. 2025 Mar;45(3):3331024251318016. doi: 10.1177/03331024251318016. Epub 2025 Mar 17.
Impact factor:
Publication type: Paper in international publication
Authors: Ashina, Messoud; Caronna, Edoardo; Diener, Hans-Christoph; Goadsby, Peter J; Pozo-Rosich, Patricia; Tassorelli, Cristina; Terwindt, Gisela M; Torres-Ferrus, Marta; Vaghi, Gloria; van der Arend, Britt W H et al.
DOI: 10.1177/03331024251318016

Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses.

PMID: 39937896
Journal: Science Advances
Year: 2025
Reference: Sci Adv. 2025 Feb 14;11(7):eado9455. doi: 10.1126/sciadv.ado9455. Epub 2025 Feb 12.
Impact factor:
Publication type: Paper in international publication
Authors: Britton, Graham J; Canales-Herrerias, Pablo; Cerutti, Andrea; Clemente, Jose C; Cunningham-Rundles, Charlotte; Dieli-Crimi, Romina; Faith, Jeremiah J; Garcia Prat, Marina; Grasset, Emilie K; Gutzeit, Cindy et al.
DOI: 10.1126/sciadv.ado9455

Harnessing Plasma Biomarkers to Predict Immunotherapy Outcomes in Hepatocellular Carcinoma: The Role of cfDNA, ctDNA, and Cytokines.

PMID: 40141436
Journal:
Year: 2025
Reference: Int J Mol Sci. 2025 Mar 20;26(6):2794. doi: 10.3390/ijms26062794.
Impact factor:
Publication type: Paper in international publication
Authors: Aransay, Ana Maria; Bermudez-Ramos, Maria; Higuera, Monica; Martin, Jose Ezequiel; Merino, Xavier; Minguez, Beatriz; Pons, Monica; Rodriguez-Frias, Francisco; Soriano-Varela, Agnes; Torrens, Maria et al.
DOI: 10.3390/ijms26062794