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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

A new pleosporalean fungus isolated from superficial to deep human clinical specimens.

PMID: 32717745
Journal: MEDICAL MYCOLOGY
Year: 2021
Reference: Med Mycol. 2021 Mar 4;59(3):278-288. doi: 10.1093/mmy/myaa055.
Impact factor:
Publication type: Paper in international publication
Authors: Cano-Lira, Jose F; Guarro, Josep; Los-Arcos, Ibai; Martin-Gomez, M Teresa; Stchigel, Alberto M; Valenzuela-Lopez, Nicomedes et al.
DOI: 10.1093/mmy/myaa055

A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors.

PMID: 33423945
Journal: European Urology Oncology
Year: 2021
Reference: Eur Urol Oncol. 2021 Jun;4(3):464-472. doi: 10.1016/j.euo.2020.12.006. Epub 2021 Jan 7.
Impact factor: 7.479
Publication type: Paper in international publication
Authors: Shreck, Evan, Gartrell, Benjamin A, Sankin, Alex, Tripathi, Abhishek, Zakopoulou, Roubini, Bamias, Aristotelis, Rodriguez-Vida, Alejo, Drakaki, Alexandra, Liu, Sandy, Kumar, Vivek et al.
DOI: 10.1016/j.euo.2020.12.006

A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors.

PMID: 33423945
Journal: European Urology Oncology
Year: 2021
Reference: Eur Urol Oncol. 2021 Jun;4(3):464-472. doi: 10.1016/j.euo.2020.12.006. Epub 2021 Jan 7.
Impact factor:
Publication type: Paper in international publication
Authors: Agarwal, Neeraj; Alonso Buznego, Lucia; Alva, Ajjai; Bamias, Aristotelis; Barata, Pedro; Bilen, Mehmet A; Carril-Ajuria, Lucia; Castellano, Daniel; De Kouchkovsky, Ivan; Devitt, Michael et al.
DOI: 10.1016/j.euo.2020.12.006

A nomogram of clinical and biologic factors to predict survival in children newly diagnosed with high-risk neuroblastoma: An International Neuroblastoma Risk Group project.

PMID: 33205902
Journal: PEDIATRIC BLOOD & CANCER
Year: 2021
Reference: Pediatr Blood Cancer. 2021 Mar;68(3):e28794. doi: 10.1002/pbc.28794. Epub 2020 Nov 18.
Impact factor: 3.167
Publication type: Paper in international publication
Authors: Irwin, Meredith S, Berthold, Frank, Hogarty, Michael, Kamijo, Takehiko, Morgenstern, Daniel, Pasqualini, Claudia, Ash, Shifra, Potschger, Ulrike, Ladenstein, Ruth, Valteau-Couanet, Dominique et al.
DOI: 10.1002/pbc.28794

A nomogram of clinical and biologic factors to predict survival in children newly diagnosed with high-risk neuroblastoma: An International Neuroblastoma Risk Group project.

PMID: 33205902
Journal: PEDIATRIC BLOOD & CANCER
Year: 2021
Reference: Pediatr Blood Cancer. 2021 Mar;68(3):e28794. doi: 10.1002/pbc.28794. Epub 2020 Nov 18.
Impact factor:
Publication type: Paper in international publication
Authors: Ash, Shifra; Berthold, Frank; Cohn, Susan L; Guo, Dongjing; Hogarty, Michael; Irwin, Meredith S; Kamijo, Takehiko; Ladenstein, Ruth; London, Wendy B; Moreno, Lucas et al.
DOI: 10.1002/pbc.28794

A notable proportion of liver transplant candidates with alcohol-related cirrhosis can be delisted because of clinical improvement.

PMID: 33746085
Journal: JOURNAL OF HEPATOLOGY
Year: 2021
Reference: J Hepatol. 2021 Aug;75(2):275-283. doi: 10.1016/j.jhep.2021.02.033. Epub 2021 Mar 18.
Impact factor: 25.083
Publication type: Paper in international publication
Authors: Pose, Elisa, Torrents, Abiguei, Reverter, Enric, Perez-Campuzano, Valeria, Campos-Varela, Isabel, Avitabile, Emma, Gratacos-Gines, Jordi, Castellote, Jose, Colmenero, Jordi, Tort, Jaume et al.
DOI: 10.1016/j.jhep.2021.02.033

A notable proportion of liver transplant candidates with alcohol-related cirrhosis can be delisted because of clinical improvement.

PMID: 33746085
Journal: JOURNAL OF HEPATOLOGY
Year: 2021
Reference: J Hepatol. 2021 Aug;75(2):275-283. doi: 10.1016/j.jhep.2021.02.033. Epub 2021 Mar 18.
Impact factor:
Publication type: Paper in international publication
Authors: Avitabile, Emma; Campos-Varela, Isabel; Castellote, Jose; Castells, Lluis; Colmenero, Jordi; Crespo, Gonzalo; Gines, Pere; Gratacos-Gines, Jordi; Perez-Campuzano, Valeria; Pose, Elisa et al.
DOI: 10.1016/j.jhep.2021.02.033

A novel antagonistic CD73 antibody for inhibition of the immunosuppressive adenosine pathway.

PMID: 34482286
Journal: MOLECULAR CANCER THERAPEUTICS
Year: 2021
Reference: Mol Cancer Ther. 2021 Nov;20(11):2250-2261. doi: 10.1158/1535-7163.MCT-21-0107. Epub 2021 Sep 4.
Impact factor:
Publication type: Paper in international publication
Authors: Adam, Paul J; Alt, Isabella; Auguste, Aurelie; Bottcher, Jark; Capdevila, Jaume; de Andrade Pereira, Bruna; Delic, Denis; Ganesan, Rajkumar; Han, Fei; Hofmann, Irmgard et al.
DOI: 10.1158/1535-7163.MCT-21-0107

A novel case of diabetes MODY1 and chronic hereditary pancreatitis: coexistence of two infrequent genetic mutations.

PMID: 33846082
Journal: Endocrinologia Diabetes y Nutricion
Year: 2021
Reference: Endocrinol Diabetes Nutr (Engl Ed). 2021 Apr 9. pii: S2530-0164(21)00077-X. doi: 10.1016/j.endinu.2020.11.008.
Impact factor: 1.417
Publication type: Letter or abstract
Authors: Cordero-Vazquez, Efrain, Filippi-Arriaga, Francesca, Hernandez, Irene Hernandez, Haman, Stephanie Solange Tasayco, Ciudin, Andreea et al.
DOI: 10.1016/j.endinu.2020.11.008

A novel experimental porcine model to assess the impact of differential pulmonary blood flow on ischemia-reperfusion injury after unilateral lung transplantation.

PMID: 33543363
Journal: Intensive care medicine experimental
Year: 2021
Reference: Intensive Care Med Exp. 2021 Feb 5;9(1):4. doi: 10.1186/s40635-021-00371-1.
Impact factor:
Publication type: Paper in international publication
Authors: Claes, Sandra; Frick, Anna Elisabeth; Heigl, Tobias; Kaes, Janne; Neyrinck, Arne P; Ordies, Sofie; Orlitova, Michaela; Saez-Gimenez, Berta; Schols, Dominique; Van Raemdonck, Dirk E et al.
DOI: 10.1186/s40635-021-00371-1

A novel model of care for simplified testing of HBV in African communities during the COVID-19 pandemic in Spain.

PMID: 34433852
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Picchio, Camila A, Nomah, Daniel K, Araujo, Silvia G, Rando-Segura, Ariadna, Fernandez, Emma, Buti, Maria, Rodriguez-Tajes, Sergio, Lens, Sabela, Rodriguez-Frias, Francisco, Lazarus, Jeffrey V et al.
DOI: 10.1038/s41598-021-96350-3

A novel model of care for simplified testing of HBV in African communities during the COVID-19 pandemic in Spain.

PMID: 34433852
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Aug 25;11(1):17063. doi: 10.1038/s41598-021-96350-3.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Silvia G; Buti, Maria; Fernandez, Emma; Lazarus, Jeffrey V; Lens, Sabela; Nomah, Daniel K; Picchio, Camila A; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco; Rodriguez-Tajes, Sergio et al.
DOI: 10.1038/s41598-021-96350-3

A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events.

PMID: 34515215
Journal: Oncology Research and Treatment
Year: 2021
Reference: Oncol Res Treat. 2021;44(10):547-556. doi: 10.1159/000518549. Epub 2021 Aug 19.
Impact factor:
Publication type: Paper in international publication
Authors: Ando, Yuichi; Bialucha, Carl U; Concin, Nicole; DiDominick, Sarah; Faris, Jason E; Mansfield, Keith; Origuchi, Shizuka; Ruan, Shiling; Schoffski, Patrick; Suarez, Cristina et al.
DOI: 10.1159/000518549

A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors.

PMID: 33686452
Journal: INVESTIGATIONAL NEW DRUGS
Year: 2021
Reference: Invest New Drugs. 2021 Aug;39(4):1089-1098. doi: 10.1007/s10637-021-01094-6. Epub 2021 Mar 8.
Impact factor: 3.85
Publication type: Paper in international publication
Authors: Azaro, Analia, Massard, Christophe, Tap, William D, Cassier, Philippe A, Merchan, Jaime, Italiano, Antoine, Anderson, Bailey, Yuen, Eunice, Yu, Danni, Oakley, Gerard 3rd et al.
DOI: 10.1007/s10637-021-01094-6

A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors.

PMID: 33686452
Journal: INVESTIGATIONAL NEW DRUGS
Year: 2021
Reference: Invest New Drugs. 2021 Aug;39(4):1089-1098. doi: 10.1007/s10637-021-01094-6. Epub 2021 Mar 8.
Impact factor:
Publication type: Paper in international publication
Authors: Anderson, Bailey; Azaro, Analia; Benhadji, Karim A; Cassier, Philippe A; Italiano, Antoine; Massard, Christophe; Merchan, Jaime; Oakley, Gerard 3rd; Pant, Shubham; Tap, William D et al.
DOI: 10.1007/s10637-021-01094-6

A Phase 2 Randomized Controlled Trial of the Efficacy and Safety of Cannabidivarin as Add-on Therapy in Participants with Inadequately Controlled Focal Seizures.

PMID: 33998885
Journal: Cannabis and Cannabinoid Research
Year: 2021
Reference: Cannabis Cannabinoid Res. 2021 Dec;6(6):528-536. doi: 10.1089/can.2020.0075. Epub 2021 Feb 15.
Impact factor: 5.8
Publication type: Paper in international publication
Authors: Toledo, Manuel, Brodie, Martin J, Czapinski, Piotr, Pazdera, Ladislav, Sander, Josemir W, Schreiber, Ashley, Nezadal, Tomas, Slonkova, Jana, Altman, Anna, Fule, Kalman et al.
DOI: 10.1089/can.2020.0075

A Phase 2 Randomized Controlled Trial of the Efficacy and Safety of Cannabidivarin as Add-on Therapy in Participants with Inadequately Controlled Focal Seizures.

PMID: 33998885
Journal: Cannabis and Cannabinoid Research
Year: 2021
Reference: Cannabis Cannabinoid Res. 2021 Dec;6(6):528-536. doi: 10.1089/can.2020.0075. Epub 2021 Feb 15.
Impact factor:
Publication type: Paper in international publication
Authors: Altman, Anna; Bagary, Manny; Banach, Marta; Brodie, Martin J; Czapinski, Piotr; Falip, Merce; Fule, Kalman; Horvath, Agnes; Kelemen, Anna; Komoly, Samuel et al.
DOI: 10.1089/can.2020.0075

A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia.

PMID: 33626197
Journal: CANCER
Year: 2021
Reference: Cancer. 2021 Jun 15;127(12):2003-2014. doi: 10.1002/cncr.33403. Epub 2021 Feb 24.
Impact factor: 6.86
Publication type: Paper in international publication
Authors: Serrano, Alfons, Labrador, Jorge, Sayas, Maria J, Foncillas, Maria A, Amador Barciela, Maria L, Olave, Maria Teresa, Colorado, Mercedes, Gascon, Adriana, Fernandez, Maria A, Simiele, Adriana et al.
DOI: 10.1002/cncr.33403

A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia.

PMID: 33626197
Journal: CANCER
Year: 2021
Reference: Cancer. 2021 Jun 15;127(12):2003-2014. doi: 10.1002/cncr.33403. Epub 2021 Feb 24.
Impact factor:
Publication type: Paper in international publication
Authors: Algarra, Lorenzo; Amador Barciela, Maria L; Barragan, Eva; Bergua Burgues, Juan; Colorado, Mercedes; Falantes, Jose F; Fernandez, Maria A; Foncillas, Maria A; Garcia, Olga; Gascon, Adriana et al.
DOI: 10.1002/cncr.33403

A phase I dose-finding, pharmacokinetics and genotyping study of olaparib and lurbinectedin in patients with advanced solid tumors.

PMID: 33627685
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Feb 24;11(1):4433. doi: 10.1038/s41598-021-82671-w.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Poveda, Andres, Oaknin, Ana, Romero, Ignacio, Guerrero-Zotano, Angel, Farinas-Madrid, Lorena, Rodriguez-Freixinos, Victor, Mallol, Pedro, Lopez-Reig, Raquel, Lopez-Guerrero, Jose Antonio et al.
DOI: 10.1038/s41598-021-82671-w

A phase I dose-finding, pharmacokinetics and genotyping study of olaparib and lurbinectedin in patients with advanced solid tumors.

PMID: 33627685
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Feb 24;11(1):4433. doi: 10.1038/s41598-021-82671-w.
Impact factor:
Publication type: Paper in international publication
Authors: Farinas-Madrid, Lorena; Guerrero-Zotano, Angel; Lopez-Guerrero, Jose Antonio; Lopez-Reig, Raquel; Mallol, Pedro; Oaknin, Ana; Poveda, Andres; Rodriguez-Freixinos, Victor; Romero, Ignacio et al.
DOI: 10.1038/s41598-021-82671-w

A Phase I study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study).

PMID: 33067614
Journal: BLOOD
Year: 2021
Reference: Blood. 2021 Mar 25;137(12):1582-1590. doi: 10.1182/blood.2020007848.
Impact factor: 23.629
Publication type: Paper in international publication
Authors: Brivio, Erica, Locatelli, Franco, Lopez-Yurda, Marta, Malone, Andrea, Diaz de Heredia, Cristina, Bielorai, Bella, Rossig, Claudia, van der Velden, Vincent H J, Ammerlaan, Anneke Cj, Thano, Adriana et al.
DOI: 10.1182/blood.2020007848

A Phase I study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study).

PMID: 33067614
Journal: BLOOD
Year: 2021
Reference: Blood. 2021 Mar 25;137(12):1582-1590. doi: 10.1182/blood.2020007848.
Impact factor:
Publication type: Paper in international publication
Authors: Ammerlaan, Anneke Cj; Bielorai, Bella; Brethon, Benoit; Brivio, Erica; Chen, Ying; Chen-Santel, Christiane; Den Boer, Monique L; Diaz de Heredia, Cristina; Locatelli, Franco; Lopez-Yurda, Marta et al.
DOI: 10.1182/blood.2020007848

A phase II study of human allogeneic liver-derived progenitor cell therapy for acute-on-chronic liver failure and acute decompensation.

PMID: 34169246
Journal: JHEP reports : innovation in hepatology
Year: 2021
Reference: JHEP Rep. 2021 Apr 18;3(4):100291. doi: 10.1016/j.jhepr.2021.100291. eCollection 2021 Aug.
Impact factor: 0
Publication type: Paper in international publication
Authors: Gordillo, Noelia, Vainilovich, Yelena, Barthel, Virginie, Clerget-Chossat, Nathalie, Sokal, Etienne M, Stoykov, Ivaylo, Michel, Sebastien, Najimi, Mustapha, Albillos, Agustin, Nevens, Frederik et al.
DOI: 10.1016/j.jhepr.2021.100291