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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

BRCA1- and BRCA2-specific in silico tools for variant interpretation in the CAGI 5 ENIGMA challenge.

PMID: 31112341
Journal: HUMAN MUTATION
Year: 2019
Reference: Hum Mutat. 2019 Sep;40(9):1593-1611. doi: 10.1002/humu.23802. Epub 2019 Jul 3.
Impact factor: 4.453
Publication type: Paper in international publication
Authors: Bonache, Sandra, Padilla, Natalia, Moles-Fernandez, Alejandro, Riera, Casandra, Montalban, Gemma, Ozkan, Selen, Ootes, Lars, de la Cruz, Xavier, Gutierrez-Enriquez, Sara, Diez, Orland et al.
DOI: 10.1002/humu.23802

BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance.

PMID: 31827092
Journal: Nature Communications
Year: 2019
Reference: Nat Commun. 2019 Dec 11;10(1):5661. doi: 10.1038/s41467-019-13530-6.
Impact factor: 11.878
Publication type: Paper in international publication
Authors: Wang, Yifan, Bernhardy, Andrea J, Nacson, Joseph, Krais, John J, Tan, Yin-Fei, Nicolas, Emmanuelle, Radke, Marc R, Handorf, Elizabeth, Llop-Guevara, Alba, Balmana, Judith et al.
DOI: 10.1038/s41467-019-13530-6

BRCA2 and Other DDR Genes in Prostate Cancer.

PMID: 30871108
Journal: Cancers
Year: 2019
Reference: Cancers (Basel). 2019 Mar 12;11(3). pii: cancers11030352. doi: 10.3390/cancers11030352.
Impact factor: 6.162
Publication type: Review in international publication
Authors: Nombela, Paz, Lozano, Rebeca, Aytes, Alvaro, Mateo, Joaquin, Olmos, David, Castro, Elena et al.
DOI: 10.3390/cancers11030352

BRIVA-LIFE-A multicenter retrospective study of the long-term use of brivaracetam in clinical practice.

PMID: 30506559
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2019
Reference: Acta Neurol Scand. 2019 Apr;139(4):360-368. doi: 10.1111/ane.13059. Epub 2018 Dec 27.
Impact factor: 2.852
Publication type: Paper in international publication
Authors: Villanueva, Vicente, Lopez-Gonzalez, Francisco Javier, Mauri, Jose Angel, Rodriguez-Uranga, Juan, Olive-Gadea, Marta, Montoya, Javier, Ruiz-Gimenez, Jesus, Zurita, Jorge, Abril, J, Toledo, M et al.
DOI: 10.1111/ane.13059

Broad consensus on the optimal sequence for the systemic treatment of metastatic breast cancer: results from a survey of Spanish medical oncologists.

PMID: 31069129
Journal: Journal of drug assessment
Year: 2019
Reference: J Drug Assess. 2019 Apr 8;8(1):62-69. doi: 10.1080/21556660.2019.1604375. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Sanchez-Rovira, Pedro, Zamora, Pilar, Salvador-Bofill, Javier, Morales, Serafin, Martinez-Janez, Noelia, Martinez-de-Duenas, Eduardo, Lluch, Ana, Illarramendi, Jose Juan, Gomez-Pardo, Patricia, Gavila Gregori, Joaquin et al.
DOI: 10.1080/21556660.2019.1604375

Broad Phenotypes of Disorders/Differences of Sex Development in MAMLD1 Patients Through Oligogenic Disease.

PMID: 31555317
Journal: Frontiers in Genetics
Year: 2019
Reference: Front Genet. 2019 Aug 29;10:746. doi: 10.3389/fgene.2019.00746. eCollection 2019.
Impact factor: 3.517
Publication type: Paper in international publication
Authors: Fluck, Christa E, Audi, Laura, Fernandez-Cancio, Monica, Sauter, Kay-Sara, Martinez de LaPiscina, Idoia, Castano, Luis, Esteva, Isabel, Camats, Nuria et al.
DOI: 10.3389/fgene.2019.00746

Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry.

PMID: 31402007
Journal: Lancet Global Health
Year: 2019
Reference: Lancet Glob Health. 2019 Sep;7(9):e1269-e1279. doi: 10.1016/S2214-109X(19)30327-4.
Impact factor: 15.873
Publication type: Paper in international publication
Authors: Sharma, Shubham, Ghewade, Babaji, Nair, Girija, Jindal, Aditya, Jayadevappa, Gayathri Devi H, Sawhney, Honney, Sarmah, Kripesh Ranjan, Saha, Kaushik, Anantharaj, Suresh, Khanna, Arjun et al.
DOI: 10.1016/S2214-109X(19)30327-4

Bronchiectasis in severe asthma: a distinct phenotype?

PMID: 30461531
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2019
Reference: Curr Opin Pulm Med. 2019 Jan;25(1):71-78. doi: 10.1097/MCP.0000000000000542.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Perez-Miranda, Javier, Traversi, Letizia, Polverino, Eva et al.
DOI: 10.1097/MCP.0000000000000542

Bronchiectasis phenotypes.

PMID: 30893106
Journal: CURRENT OPINION IN PULMONARY MEDICINE
Year: 2019
Reference: Curr Opin Pulm Med. 2019 May;25(3):281-288. doi: 10.1097/MCP.0000000000000569.
Impact factor: 2.541
Publication type: Review in international publication
Authors: Chang-Macchiu, Patricia, Traversi, Letizia, Polverino, Eva et al.
DOI: 10.1097/MCP.0000000000000569

Brugada Syndrome: anaesthetic considerations and management algorithm.

PMID: 30394071
Journal: Minerva Anestesiologica
Year: 2019
Reference: Minerva Anestesiol. 2019 Feb;85(2):173-188. doi: 10.23736/S0375-9393.18.13170-1. Epub 2018 Oct 30.
Impact factor: 2.84
Publication type: Paper in international publication
Authors: Campuzano, Oscar, Sarquella-Brugada, Georgia, Abad-Motos, Ane, Zaballos-Garcia, Matilde, Abad-Torrent, Ana, Prieto-Gundin, Alejandra, Brugada, Josep, Brugada, Ramon, Ripolles-Melchor, Javier, Espinosa, Angel et al.
DOI: 10.23736/S0375-9393.18.13170-1

Budget Impact Analysis Of Subcutaneous Belimumab In Patients With Systemic Lupus Erythematosus In Spain.

PMID: 31824182
Journal: ClinicoEconomics and outcomes research : CEOR
Year: 2019
Reference: Clinicoecon Outcomes Res. 2019 Dec 5;11:757-765. doi: 10.2147/CEOR.S218464. eCollection 2019.
Impact factor: 0
Publication type: Paper in international publication
Authors: Calvo-Alen, Jaime, Crespo, Carlos, Robles-Marhuenda, Angel, Smolen, Lee, Cortes-Hernandez, Josefina, Cevey, Maria et al.
DOI: 10.2147/CEOR.S218464

Burkitt-like lymphoma with 11q aberration: A germinal center derived lymphoma genetically unrelated to Burkitt lymphoma.

PMID: 30733272
Journal: HAEMATOLOGICA
Year: 2019
Reference: Haematologica. 2019 Sep;104(9):1822-1829. doi: 10.3324/haematol.2018.207928. Epub 2019 Feb 7.
Impact factor: 7.57
Publication type: Paper in international publication
Authors: Ferrandez, Antonio, Garrido, Marta, Garcia-Bragado, Federico, de la Maya, Maria Dolores, Vagace, Jose Manuel, Panizo, Carlos Manuel, Astigarraga, Itziar, Andres, Mara, Jaffe, Elaine S, Campo, Elias et al.
DOI: 10.3324/haematol.2018.207928

Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer.

PMID: 31566937
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2019
Reference: N Engl J Med. 2019 Dec 26;381(26):2506-2518. doi: 10.1056/NEJMoa1911206. Epub 2019 Sep 30.
Impact factor: 70.67
Publication type: Paper in international publication
Authors: de Wit, Ronald, de Bono, Johann, Sternberg, Cora N, Fizazi, Karim, Tombal, Bertrand, Wulfing, Christian, Kramer, Gero, Eymard, Jean-Christophe, Bamias, Aristotelis, Carles, Joan et al.
DOI: 10.1056/NEJMoa1911206

Calcitonin gene-related peptide in migraine: from pathophysiology to treatment.

PMID: 31326215
Journal: NEUROLOGIA
Year: 2019
Reference: Neurologia. 2019 Jul 17. pii: S0213-4853(19)30075-1. doi: 10.1016/j.nrl.2019.03.013.
Impact factor: 2.038
Publication type: Review in national publication
Authors: Sanchez Del Rio, M, Santos-Lasaosa, S, Belvis, R, Cuadrado, M L, Diaz-Insa, S, Gago-Veiga, A, Guerrero-Peral, A L, Huerta, M, Irimia, P, Lainez, J M et al.
DOI: 10.1016/j.nrl.2019.03.013

Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue.

PMID: 30277821
Journal: FASEB JOURNAL
Year: 2019
Reference: FASEB J. 2019 Feb;33(2):2343-2358. doi: 10.1096/fj.201800310R. Epub 2018 Oct 2.
Impact factor: 5.391
Publication type: Paper in international publication
Authors: Vila, Maria, Cervela, Luis, de Marco, Marina, Gama-Perez, Pau, Gonzalez-Franquesa, Alba, Statuto, Lucia, Vilallonga, Ramon, Simo, Rafael, Garcia-Roves, Pablo M, Villena, Josep A et al.
DOI: 10.1096/fj.201800310R

Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2.

PMID: 30915659
Journal: BASIC RESEARCH IN CARDIOLOGY
Year: 2019
Reference: Basic Res Cardiol. 2019 Mar 26;114(3):21. doi: 10.1007/s00395-019-0730-5.
Impact factor: 6.47
Publication type: Paper in international publication
Authors: Aluja, David, Inserte, Javier, Penela, Petronila, Ramos, Paula, Ribas, Catalina, Iniguez, Miguel Angel, Mayor, Federico Jr, Garcia-Dorado, David et al.
DOI: 10.1007/s00395-019-0730-5

Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation and Study of Diabetic Nephropathy with Atrasentan: what was learned about the treatment of diabetic kidney disease with canagliflozin and atrasentan?

PMID: 31198532
Journal: Clinical Kidney Journal
Year: 2019
Reference: Clin Kidney J. 2019 May 31;12(3):313-321. doi: 10.1093/ckj/sfz070. eCollection 2019 Jun.
Impact factor: 2.975
Publication type: Paper in international publication
Authors: Fernandez-Fernandez, Beatriz, Fernandez-Prado, Raul, Gorriz, Jose Luis, Martinez-Castelao, Alberto, Navarro-Gonzalez, Juan F, Porrini, Esteban, Soler, Maria Jose, Ortiz, Alberto et al.
DOI: 10.1093/ckj/sfz070

Cancer Core Europe: A translational research infrastructure for a European mission on cancer.

PMID: 30657633
Journal: Molecular Oncology
Year: 2019
Reference: Mol Oncol. 2019 Mar;13(3):521-527. doi: 10.1002/1878-0261.12447. Epub 2019 Feb 2.
Impact factor: 5.962
Publication type: Review in national publication
Authors: Eggermont, Alexander M M, Apolone, Giovanni, Baumann, Michael, Caldas, Carlos, Celis, Julio E, de Lorenzo, Francesco, Ernberg, Ingemar, Ringborg, Ulrik, Rowell, John, Tabernero, Josep et al.
DOI: 10.1002/1878-0261.12447

Candidemia in solid organ transplant recipients in Spain: epidemiological trends and determinants of outcome.

PMID: 31610077
Journal: Transplant Infectious Disease
Year: 2019
Reference: Transpl Infect Dis. 2019 Dec;21(6):e13195. doi: 10.1111/tid.13195. Epub 2019 Oct 26.
Impact factor: 2.112
Publication type: Paper in international publication
Authors: Fernandez-Ruiz, Mario, Cardozo, Celia, Salavert, Miguel, Aguilar-Guisado, Manuela, Escola-Verge, Laura, Munoz, Patricia, Gioia, Francesca, Montejo, Miguel, Merino, Paloma, Cuervo, Guillermo et al.
DOI: 10.1111/tid.13195

Cannabis for pain in orthopedics: a systematic review focusing on study methodology

PMID: 31782292
Journal: CANADIAN JOURNAL OF SURGERY
Year: 2019
Reference: Can J Surg. 2019 Dec 1;62(6):001018. doi: 10.1503/cjs.001018.
Impact factor: 2.306
Publication type: Review in international publication
Authors: Madden, Kim, George, Annie, van der Hoek, Niek J., Borim, Felipe Moreira, Mammen, George, Bhandari, Mohit et al.
DOI: 10.1503/cjs.001018

CanStem111P trial: a Phase III study of napabucasin plus nab-paclitaxel with gemcitabine.

PMID: 30768369
Journal: Future Oncology
Year: 2019
Reference: Future Oncol. 2019 Apr;15(12):1295-1302. doi: 10.2217/fon-2018-0903. Epub 2019 Feb 15.
Impact factor: 2.279
Publication type: Paper in international publication
Authors: Sonbol, Mohamad Bassam, Ahn, Daniel H, Goldstein, David, Okusaka, Takuji, Tabernero, Josep, Macarulla, Teresa, Reni, Michele, Li, Chung-Pin, O'Neil, Bert, Cutsem, Eric Van et al.
DOI: 10.2217/fon-2018-0903

Carcinoembryonic Antigen Levels and Survival in Stage III Colon Cancer: Post hoc Analysis of the MOSAIC and PETACC-8 Trials.

PMID: 31263053
Journal: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
Year: 2019
Reference: Cancer Epidemiol Biomarkers Prev. 2019 Jul;28(7):1153-1161. doi: 10.1158/1055-9965.EPI-18-0867.
Impact factor: 5.057
Publication type: Paper in international publication
Authors: Auclin, Edouard, Taieb, Julien, Lepage, Come, Aparicio, Thomas, Faroux, Roger, Mini, Enrico, Folprecht, Gunnar, Salazar, Ramon, Benetkiewicz, Magdalena, Banzi, Maria et al.
DOI: 10.1158/1055-9965.EPI-18-0867

Cardiac innervation in acute myocardial ischaemia/reperfusion injury and cardioprotection.

PMID: 30796814
Journal: CARDIOVASCULAR RESEARCH
Year: 2019
Reference: Cardiovasc Res. 2019 Jun 1;115(7):1167-1177. doi: 10.1093/cvr/cvz053.
Impact factor: 7.014
Publication type: Paper in international publication
Authors: Hausenloy, Derek J, Botker, Hans Erik, Ferdinandy, Peter, Heusch, Gerd, Ng, G Andre, Redington, Andrew, Garcia-Dorado, David et al.
DOI: 10.1093/cvr/cvz053

Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel.

PMID: 31296297
Journal: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Year: 2019
Reference: J Am Coll Cardiol. 2019 Jul 16;74(2):238-256. doi: 10.1016/j.jacc.2019.05.024.
Impact factor: 18.639
Publication type: Review in international publication
Authors: Eitel, Ingo, Fernandez-Jimenez, Rodrigo, Friedrich, Matthias G, Garcia-Dorado, David, Hausenloy, Derek J, Kim, Raymond J, Kozerke, Sebastian, Kramer, Christopher M, Salerno, Michael, Sanchez-Gonzalez, Javier et al.
DOI: 10.1016/j.jacc.2019.05.024