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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.

PMID: 31104069
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 May 28;321(20):1993-2002. doi: 10.1001/jama.2019.5358.
Impact factor:
Publication type: Paper in international publication
Authors: Barie, Philip S; Crowther, Mark; Daga, Mradul Kumar; Esmon, Charles T; Fareed, Jawed; Ferrer Roca, Ricard; Fineberg, David; Francois, Bruno; Gando, Satoshi; Gorelick, Kenneth J et al.
DOI: 10.1001/jama.2019.5358

Effect of Aflibercept Plus Modified FOLFOX6 Induction Chemotherapy Before Standard Chemoradiotherapy and Surgery in Patients With High-Risk Rectal Adenocarcinoma: The GEMCAD 1402 Randomized Clinical Trial.

PMID: 31465088
Journal: JAMA Oncology
Year: 2019
Reference: JAMA Oncol. 2019;5(11):1566-1573. doi: 10.1001/jamaoncol.2019.2294.
Impact factor: 22.416
Publication type: Paper in international publication
Authors: Garcia-Albeniz, Xabier, Jain, Rakesh K, Macias, Ismael, Montagut, Clara, Fernandez-Martos, Carlos, Pericay, Carles, Losa, Ferran, Garcia-Carbonero, Rocio, Layos, Laura, Rodriguez-Salas, Nuria et al.
DOI: 10.1001/jamaoncol.2019.2294

Effect of Aflibercept Plus Modified FOLFOX6 Induction Chemotherapy Before Standard Chemoradiotherapy and Surgery in Patients With High-Risk Rectal Adenocarcinoma: The GEMCAD 1402 Randomized Clinical Trial.

PMID: 31465088
Journal: JAMA Oncology
Year: 2019
Reference: JAMA Oncol. 2019;5(11):1566-1573. doi: 10.1001/jamaoncol.2019.2294.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Orduna, Vicente; Capdevila, Jaume; Fernandez-Martos, Carlos; Gallego, Javier; Garcia-Albeniz, Xabier; Garcia-Carbonero, Rocio; Guash, Inmaculada; Jain, Rakesh K; Layos, Laura; Lopez, Carlos et al.
DOI: 10.1001/jamaoncol.2019.2294

Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).

PMID: 31248390
Journal: BMC Pediatrics
Year: 2019
Reference: BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8.
Impact factor: 1.983
Publication type: Paper in international publication
Authors: Naulaers, Gunnar, van Bel, Frank, Allegaert, Karel, Naulaers, Gunnar, Bassler, Dirk, Klebermass-Schrehof, Katrin, Vento, Maximo, Guimaraes, Hercilia, Stiris, Tom, Cattarossi, Luigi et al.
DOI: 10.1186/s12887-019-1566-8

Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).

PMID: 31248390
Journal: BMC Pediatrics
Year: 2019
Reference: BMC Pediatr. 2019 Jun 27;19(1):210. doi: 10.1186/s12887-019-1566-8.
Impact factor:
Publication type: Paper in international publication
Authors: Allegaert, Karel; Allegaert, Karel; Andresson, Pille; Annink, Kim V; Annink, Kim V; Baraldi, Eugenio; Barbarini, Mario; Barroso, Rosalina; Bassler, Dirk; Bassler, Dirk et al.
DOI: 10.1186/s12887-019-1566-8

Effect of brivaracetam on the anger levels of epilepsy patients. A prospective open-labelled controlled study.

PMID: 31079028
Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Year: 2019
Reference: Seizure. 2019 Jul;69:198-203. doi: 10.1016/j.seizure.2019.04.021. Epub 2019 May 1.
Impact factor: 2.765
Publication type: Paper in international publication
Authors: Toledo, Manuel, Abraira, Laura, Mazuela, Gonzalo, Quintana, Manuel, Cazorla, Sonia, Santamarina, Estevo et al.
DOI: 10.1016/j.seizure.2019.04.021

Effect of brivaracetam on the anger levels of epilepsy patients. A prospective open-labelled controlled study.

PMID: 31079028
Journal: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Year: 2019
Reference: Seizure. 2019 Jul;69:198-203. doi: 10.1016/j.seizure.2019.04.021. Epub 2019 May 1.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, Laura; Cazorla, Sonia; Mazuela, Gonzalo; Quintana, Manuel; Santamarina, Estevo; Toledo, Manuel et al.
DOI: 10.1016/j.seizure.2019.04.021

Effect of continuous positive airway pressure in patients with true refractory hypertension and sleep apnea: a post-hoc intention-to-treat analysis of the HIPARCO randomized clinical trial.

PMID: 30676482
Journal: JOURNAL OF HYPERTENSION
Year: 2019
Reference: J Hypertens. 2019 Jun;37(6):1269-1275. doi: 10.1097/HJH.0000000000002053.
Impact factor: 4.209
Publication type: Paper in international publication
Authors: Navarro-Soriano, Cristina, Martinez-Garcia, Miguel-Angel, Torres, Gerard, Barbe, Ferran, Caballero-Eraso, Candela, Lloberes, Patricia, Diaz Cambriles, Trinidad, Somoza, Maria, Masa, Juan F, Gonzalez, Monica et al.
DOI: 10.1097/HJH.0000000000002053

Effect of continuous positive airway pressure in patients with true refractory hypertension and sleep apnea: a post-hoc intention-to-treat analysis of the HIPARCO randomized clinical trial.

PMID: 30676482
Journal: JOURNAL OF HYPERTENSION
Year: 2019
Reference: J Hypertens. 2019 Jun;37(6):1269-1275. doi: 10.1097/HJH.0000000000002053.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Caballero-Eraso, Candela; Calhoun, David; Campos-Rodriguez, Francisco; de la Pena, Monica; Diaz Cambriles, Trinidad; Feced Olmos, Laura; Garcia-Ortega, Alberto; Garcia-Rio, Francisco; Gonzalez, Monica et al.
DOI: 10.1097/HJH.0000000000002053

Effect of extracranial lesion severity on outcome of endovascular thrombectomy in patients with anterior circulation tandem occlusion: analysis of the TITAN registry.

PMID: 30842304
Journal: Journal of NeuroInterventional Surgery
Year: 2019
Reference: J Neurointerv Surg. 2019 Oct;11(10):970-974. doi: 10.1136/neurintsurg-2018-014629. Epub 2019 Mar 6.
Impact factor: 3.925
Publication type: Paper in international publication
Authors: Boutchakova, Maria, Siddiqui, Adnan H, Lapergue, Bertrand, Dorn, Franziska, Cognard, Christophe, Killer-Oberpfalzer, Monika, Mangiafico, Salvatore, Ribo, Marc, Psychogios, Marios-Nikos, Labeyrie, Marc-Antoine et al.
DOI: 10.1136/neurintsurg-2018-014629

Effect of extracranial lesion severity on outcome of endovascular thrombectomy in patients with anterior circulation tandem occlusion: analysis of the TITAN registry.

PMID: 30842304
Journal: Journal of NeuroInterventional Surgery
Year: 2019
Reference: J Neurointerv Surg. 2019 Oct;11(10):970-974. doi: 10.1136/neurintsurg-2018-014629. Epub 2019 Mar 6.
Impact factor:
Publication type: Paper in international publication
Authors: Alawieh, Ali; Anadani, Mohammad; Anxionnat, Rene; Biondi, Alessandra; Boutchakova, Maria; Bracard, Serge; Cognard, Christophe; Dorn, Franziska; Eiden, Sebastian; Gory, Benjamin et al.
DOI: 10.1136/neurintsurg-2018-014629

Effect of Glucose Improvement on Spirometric Maneuvers in Patients With Type 2 Diabetes: The Sweet Breath Study.

PMID: 30705064
Journal: DIABETES CARE
Year: 2019
Reference: Diabetes Care. 2019 Apr;42(4):617-624. doi: 10.2337/dc18-1948. Epub 2019 Jan 31.
Impact factor: 15.27
Publication type: Paper in international publication
Authors: Gutierrez-Carrasquilla, Liliana, Sanchez, Enric, Barbe, Ferran, Dalmases, Mireia, Lopez-Cano, Carolina, Hernandez, Marta, Rius, Ferran, Carmona, Paola, Hernandez, Cristina, Simo, Rafael et al.
DOI: 10.2337/dc18-1948

Effect of Glucose Improvement on Spirometric Maneuvers in Patients With Type 2 Diabetes: The Sweet Breath Study.

PMID: 30705064
Journal: DIABETES CARE
Year: 2019
Reference: Diabetes Care. 2019 Apr;42(4):617-624. doi: 10.2337/dc18-1948. Epub 2019 Jan 31.
Impact factor:
Publication type: Paper in international publication
Authors: Barbe, Ferran; Carmona, Paola; Dalmases, Mireia; Gutierrez-Carrasquilla, Liliana; Hernandez, Cristina; Hernandez, Marta; Lecube, Albert; Lopez-Cano, Carolina; Rius, Ferran; Sanchez, Enric et al.
DOI: 10.2337/dc18-1948

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials.

PMID: 29521573
Journal: Multiple Sclerosis Journal
Year: 2019
Reference: Mult Scler. 2019 Apr;25(4):565-573. doi: 10.1177/1352458518763089. Epub 2018 Mar 9.
Impact factor: 5.649
Publication type: Paper in international publication
Authors: Kappos, Ludwig, Barkhof, Frederik, Edan, Gilles, Freedman, Mark S, Montalban, Xavier, Muller-Myhsok, Bertram, Hemmer, Bernhard, Jeffery, Douglas, Hartung, Hans-Peter, Cook, Stuart et al.
DOI: 10.1177/1352458518763089

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials.

PMID: 29521573
Journal: Multiple Sclerosis Journal
Year: 2019
Reference: Mult Scler. 2019 Apr;25(4):565-573. doi: 10.1177/1352458518763089. Epub 2018 Mar 9.
Impact factor:
Publication type: Paper in international publication
Authors: Andlauer, Till Fm; Arnason, Barry; Barkhof, Frederik; Buck, Dorothea; Comi, Giancarlo; Cook, Stuart; Edan, Gilles; Filippi, Massimo; Freedman, Mark S; Hartung, Hans-Peter et al.
DOI: 10.1177/1352458518763089

Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.

PMID: 31184740
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 Jun 11;321(22):2175-2182. doi: 10.1001/jama.2019.7234.
Impact factor: 51.273
Publication type: Paper in international publication
Authors: Lopez, Alexandra, de la Torre, Maria-Carmen, Keough, Elena, Arauzo, Vanesa, Hermosa, Cecilia, Sanchez, Carmen, Tizon, Ana, Tenza, Eva, Laborda, Cesar, Cabanes, Sara et al.
DOI: 10.1001/jama.2019.7234

Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.

PMID: 31184740
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 Jun 11;321(22):2175-2182. doi: 10.1001/jama.2019.7234.
Impact factor:
Publication type: Paper in international publication
Authors: Arauzo, Vanesa; Arnau, Anna; Cabanes, Sara; de la Torre, Maria-Carmen; Del Mar Fernandez, Maria; Fernandez, Rafael; Garcia, Carolina; Gonzalez-Castro, Alejandro; Hermosa, Cecilia; Hernandez, Gonzalo et al.
DOI: 10.1001/jama.2019.7234

Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial.

PMID: 31287523
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 Jul 9;322(2):123-133. doi: 10.1001/jama.2019.9053.
Impact factor: 51.273
Publication type: Paper in international publication
Authors: Bastidas, Adriana, de la Serna, Javier, El Idrissi, Mohamed, Oostvogels, Lidia, Quittet, Philippe, Lopez-Jimenez, Javier, Vural, Filiz, Pohlreich, David, Zuckerman, Tsila, Issa, Nicolas C et al.
DOI: 10.1001/jama.2019.9053

Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial.

PMID: 31287523
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 Jul 9;322(2):123-133. doi: 10.1001/jama.2019.9053.
Impact factor:
Publication type: Paper in international publication
Authors: Abhyankar, Sunil; Bastidas, Adriana; Boeckh, Michael J; Campins, Magda; Campora, Laura; de la Serna, Javier; El Idrissi, Mohamed; Gaidano, Gianluca; Grigg, Andrew; Heineman, Thomas C et al.
DOI: 10.1001/jama.2019.9053

Effect of sirolimus exposure on the need for pre-emptive antiviral therapy for CMV infection after allogeneic hematopoietic stem cell transplantation.

PMID: 30639821
Journal: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Year: 2019
Reference: Biol Blood Marrow Transplant. 2019 May;25(5):1022-1030. doi: 10.1016/j.bbmt.2019.01.012. Epub 2019 Jan 10.
Impact factor: 3.599
Publication type: Paper in international publication
Authors: Pinana, Jose Luis, Martino, Rodrigo, Solano, Carlos, Guglieri-Lopez, Beatriz, Perez-Pitarch, Alejandro, Garcia-Cadenas, Irene, Gimenez, Estela, Barba, Pere, Rabella, Nuria, Hernandez-Boluda, Juan Carlos et al.
DOI: 10.1016/j.bbmt.2019.01.012

Effect of sirolimus exposure on the need for pre-emptive antiviral therapy for CMV infection after allogeneic hematopoietic stem cell transplantation.

PMID: 30639821
Journal: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Year: 2019
Reference: Biol Blood Marrow Transplant. 2019 May;25(5):1022-1030. doi: 10.1016/j.bbmt.2019.01.012. Epub 2019 Jan 10.
Impact factor:
Publication type: Paper in international publication
Authors: Barba, Pere; Esquirol, Albert; Ferriols-Lisart, Rafael; Fox, Laura; Garcia-Cadenas, Irene; Gimenez, Estela; Guglieri-Lopez, Beatriz; Hernandez-Boluda, Juan Carlos; Martino, Rodrigo; Navarro, David et al.
DOI: 10.1016/j.bbmt.2019.01.012

Effect of Superior Ovarian Nerve and Plexus Nerve Sympathetic Denervation on Ovarian-Derived Infertility Provoked by Estradiol Exposure to Rats.

PMID: 31024331
Journal: Frontiers in Physiology
Year: 2019
Reference: Front Physiol. 2019 Apr 9;10:349. doi: 10.3389/fphys.2019.00349. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Del Campo, Miguel; Lara, Hernan E; Piquer, Beatriz; Sridhar, Arun; Witherington, Jason et al.
DOI: 10.3389/fphys.2019.00349

Effectiveness and cost-effectiveness of a multicomponent intervention to improve medication adherence in people with depressive disorders - MAPDep: a study protocol for a cluster randomized controlled trial.

PMID: 30863020
Journal: Patient Preference and Adherence
Year: 2019
Reference: Patient Prefer Adherence. 2019 Feb 22;13:309-319. doi: 10.2147/PPA.S172963. eCollection 2019.
Impact factor: 2.097
Publication type: Paper in international publication
Authors: Del Pino-Sedeno, Tasmania, Penate, Wenceslao, de Las Cuevas, Carlos, Valcarcel-Nazco, Cristina, Fumero, Ascension, Serrano-Perez, Pedro Guillermo, Acosta Artiles, Francisco Javier, Ramos Garcia, Vanesa, Leon Salas, Beatriz, Bejarano-Quisoboni, Daniel et al.
DOI: 10.2147/PPA.S172963

Effectiveness and cost-effectiveness of a multicomponent intervention to improve medication adherence in people with depressive disorders - MAPDep: a study protocol for a cluster randomized controlled trial.

PMID: 30863020
Journal: Patient Preference and Adherence
Year: 2019
Reference: Patient Prefer Adherence. 2019 Feb 22;13:309-319. doi: 10.2147/PPA.S172963. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Acosta Artiles, Francisco Javier; Bejarano-Quisoboni, Daniel; de Las Cuevas, Carlos; Del Pino-Sedeno, Tasmania; Fumero, Ascension; Leon Salas, Beatriz; Penate, Wenceslao; Ramos Garcia, Vanesa; Serrano-Perez, Pedro Guillermo; Trujillo-Martin, Maria M et al.
DOI: 10.2147/PPA.S172963