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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

Circulating Tumor Cell Count Is a Prognostic Factor in Metastatic Colorectal Cancer Patients Receiving First-Line Chemotherapy Plus Bevacizumab: A Spanish Cooperative Group for the Treatment of Digestive Tumors Study.

PMID: 22643538
Journal: ONCOLOGIST
Year: 2012
Reference: Oncologist. 2012;17(7):947-55. doi: 10.1634/theoncologist.2012-0048. Epub 2012 May 29.
Impact factor: 3.812
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1634/theoncologist.2012-0048

Circulating tumour cells in early breast cancer.

PMID: 22935235
Journal: LANCET ONCOLOGY
Year: 2012
Reference: Lancet Oncol. 2012 Sep;13(9):e370; author reply e370. doi: 10.1016/S1470-2045(12)70316-9.
Impact factor: 22.589
Publication type: Letter whit IF
Authors: De Mattos-Arruda, Leticia, Tabernero, Josep, Seoane, Joan, Cortes, Javier et al.
DOI: 10.1016/S1470-2045(12)70316-9

Cisplatin and gemcitabine administered every two weeks in patients with locally advanced or metastatic urothelial carcinoma and impaired renal function.

PMID: 22595043
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2012
Reference: Eur J Cancer. 2012 Aug;48(12):1816-21. doi: 10.1016/j.ejca.2012.04.002. Epub 2012 May 16.
Impact factor: 5.536
Publication type: Paper in international publication
Authors: , , , , , , , et al.
DOI: 10.1016/j.ejca.2012.04.002

Citicoline in pre-clinical animal models of stroke: A meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial.

PMID: 22845688
Journal: JOURNAL OF NEUROCHEMISTRY
Year: 2012
Reference: J Neurochem. 2012 Oct;123(2):217-25. doi: 10.1111/j.1471-4159.2012.07891.x. Epub 2012 Aug 23.
Impact factor: 4.061
Publication type: Review in international publication
Authors: Montaner, J, Rosell, A, Campos, M, Garcia-Bonilla, L, Bustamante, A, Giralt, D et al.
DOI: 10.1111/j.1471-4159.2012.07891.x

Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial).

PMID: 22691567
Journal: LANCET
Year: 2012
Reference: Lancet. 2012 Jul 28;380(9839):349-57. doi: 10.1016/S0140-6736(12)60813-7. Epub 2012 Jun 11.
Impact factor: 38.278
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/S0140-6736(12)60813-7

Clinical audit of COPD patients requiring hospital admissions in Spain: AUDIPOC study.

PMID: 22911875
Journal: PLoS One
Year: 2012
Reference: PLoS One. 2012;7(7):e42156. Epub 2012 Jul 31.
Impact factor: 4.092
Publication type: Paper in international publication
Authors: Lopez-Campos, Jose Luis, Pozo-Rodriguez, Francisco, Medievilla, Cecilia Alonso, Falces Sierra, Armando, Soto Campos, Gregorio, Romero Valero, Fernando, Blanco Saez, Isidro, Sanchez Gomez, Jesus, Arenas de la Riva, Marisol, Cobos Ceballos, Maria Jesus et al.
DOI: 10.1371/journal.pone.0042156

Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices.

PMID: 22535857
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2012
Reference: JAMA. 2012 Apr 25;307(16):1727-35.
Impact factor: 30.026
Publication type: Paper in international publication
Authors: Rees, David, Athan, Eugene, Thierer, Jorge, Casabe, Jose, Cortes, Claudia, Altclas, Javier, Kogan, Silvia, Spelman, Denis, Athan, Eugene, Harris, Owen et al.
DOI: 10.1001/jama.2012.497

Clinical experience of bendamustine treatment for non-Hodgkin lymphoma and chronic lymphocytic leukemia in Spain.

PMID: 22154023
Journal: LEUKEMIA RESEARCH
Year: 2012
Reference: Leuk Res. 2012 Jun;36(6):709-14. Epub 2011 Dec 7.
Impact factor: 2.923
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.leukres.2011.10.024

Clinical experience with daptomycin for the treatment of patients with knee and hip periprosthetic joint infections.

PMID: 22511636
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2012
Reference: J Antimicrob Chemother. 2012 Jul;67(7):1749-54. doi: 10.1093/jac/dks119. Epub 2012 Apr 17.
Impact factor: 5.068
Publication type: Paper in international publication
Authors: Barro Ojeda, Victor, Corona Perez-Cardona, Pablo S, Guerra Farfan, Ernesto, Amat Mateu, Carles, Flores Sanchez, Xavier, Pigrau Serrallach, Carlos, Rodriguez Pardo, Dolors et al.
DOI: 10.1093/jac/dks119

[Clinical features and hospital complications of patients with acute coronary syndromes according to smoking habits.]

PMID: 21453939
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Apr 21;138(10):422-8. Epub 2011 Mar 31.
Impact factor: 1.385
Publication type: Paper in national publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.medcli.2011.01.016

Clinical guidelines for late-onset Pompe disease.

PMID: 22492103
Journal: Revista de neurologia
Year: 2012
Reference: Rev Neurol. 2012 Apr 16;54(8):497-507.
Impact factor:
Publication type: Letter or abstract
Authors: Barba-Romero, M A, Barrot, E, Bautista-Lorite, J, Gutierrez-Rivas, E, Illa, I, Jimenez, L M, Ley-Martos, M, Lopez de Munain, A, Pardo, J, Pascual-Pascual, S I et al.
DOI:

Clinical, Molecular and Biochemical Characterization of Nine Spanish Families with Conradi-Hunermann-Happle Syndrome: New Insights into CDPX2 With A Comprehensive Review of the Literature.

PMID: 22121851
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2012
Reference: Br J Dermatol. 2012 Apr;166(4):830-838. doi: 10.1111/j.1365-2133.2011.10756.x. Epub 2012 Mar 2.
Impact factor: 3.666
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1111/j.1365-2133.2011.10756.x

[Clinical practice guidelines for assessment and treatment of transsexualism. SEEN Identity and Sexual Differentiation Group (GIDSEEN)].

PMID: 22542505
Journal: Endocrinología y nutrición
Year: 2012
Reference: Endocrinol Nutr. 2012 Jun-Jul;59(6):367-82. doi: 10.1016/j.endonu.2012.02.001. Epub 2012 Apr 26.
Impact factor:
Publication type: Letter or abstract
Authors: Moreno-Perez, Oscar, Esteva De Antonio, Isabel, Albero, Ramon, Almaraz, Maria Cruz, Alvarez-Diz, Jose Antonio, Audi, Laura, Becerra, Antonio, Castano, Luis, Esteva, Isabel, Fernandez Sanchez-Barbudo, Miguel et al.
DOI: 10.1016/j.endonu.2012.02.001

Clinical Presentation of Invasive Pneumococcal Disease in Spain in the Era of Heptavalent Conjugate Vaccine.

PMID: 22173137
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2012
Reference: Pediatr Infect Dis J. 2012 Feb;31(2):124-8.
Impact factor: 3.577
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1097/INF.0b013e318241d09e

[Clinical profile and treatment of elderly patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease in Spanish Internal Medicine services. ECCO study].

PMID: 22118975
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Apr 28;138(11):461-7. Epub 2011 Nov 25.
Impact factor: 1.385
Publication type: Paper in national publication
Authors: Custardoy, Juan, Lopez Garcia, Francisco, San Roman Teran, Carlos, Recio, Jesus, Soriano, Joan B, de Rodas, Santiago Mola Caballero, Garcia, Francisco Lopez, Torregrosa, Jose Antonio Carratala, Cervera, Gemma Penades, Olavarrieta, Juan Custardoy et al.
DOI: 10.1016/j.medcli.2011.05.030

Clinical utility of chromosomal microarray analysis in invasive prenatal diagnosis.

PMID: 21975797
Journal: HUMAN GENETICS
Year: 2012
Reference: Hum Genet. 2012 Mar;131(3):513-23.
Impact factor: 5.069
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1007/s00439-011-1095-5

[Clinical variability of polymicrogiria: report of 35 new cases and review of the literature].

PMID: 22972573
Journal: REVISTA DE NEUROLOGIA
Year: 2012
Reference: Rev Neurol. 2012 Sep 16;55(6):321-9.
Impact factor:
Publication type: Letter or abstract
Authors: Flotats-Bastardas, M, Ortega-Aznar, A, Boronat-Guerrero, S, Raspall-Chaure, M, Del Toro-Riera, M, Munell, F, Macaya-Ruiz, A, Roig-Quilis, M, Vazquez-Mendez, E, Sanchez-Montanez, A et al.
DOI:

Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy.

PMID: 22889300
Journal: Retrovirology
Year: 2012
Reference: Retrovirology. 2012 Aug 13;9:68. doi: 10.1186/1742-4690-9-68.
Impact factor: 6.47
Publication type: Paper in international publication
Authors: Betancor, Gilberto, Garriga, Cesar, Puertas, Maria C, Nevot, Maria, Anta, Lourdes, Blanco, Jose L, Perez-Elias, M Jesus, de Mendoza, Carmen, Martinez, Miguel A, Martinez-Picado, Javier et al.
DOI: 10.1186/1742-4690-9-68

Clofarabine-based chemotherapy for relapsed/refractory adult acute lymphoblastic leukemia and lymphoblastic lymphoma. The Spanish experience.

PMID: 22431002
Journal: AMERICAN JOURNAL OF HEMATOLOGY
Year: 2012
Reference: Am J Hematol. 2012 Jun;87(6):631-4. doi: 10.1002/ajh.23167. Epub 2012 Mar 19.
Impact factor: 4.671
Publication type: Letter whit IF
Authors: , , , , , , , , , et al.
DOI: 10.1002/ajh.23167

Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.

PMID: 22291008
Journal: JOURNAL OF BIOLOGICAL CHEMISTRY
Year: 2012
Reference: J Biol Chem. 2012 Mar 23;287(13):9682-93. doi: 10.1074/jbc.M111.279224. Epub 2012 Jan 30.
Impact factor: 4.773
Publication type: Paper in international publication
Authors: Comas-Casellas, Emma, Martinez-Barriocanal, Agueda, Miro, Francesc, Ejarque-Ortiz, Aroa, Schwartz, Simo Jr, Martin, Margarita, Sayos, Joan et al.
DOI: 10.1074/jbc.M111.279224

Co-factor-enhanced food allergy.

PMID: 22845005
Journal: ALLERGY
Year: 2012
Reference: Allergy. 2012 Oct;67(10):1316-8. doi: 10.1111/j.1398-9995.2012.02877.x.. Epub 2012 Jul 30.
Impact factor: 6.271
Publication type: Paper in international publication
Authors: Sala-Cunill, A, Cardona, V, Luengo, O, Garriga, T, Labrador-Horrillo, M, Guilarte, M, Soto, L, Izquierdo, A et al.
DOI: 10.1111/j.1398-9995.2012.02877.x.

Cognitive assessment protocol design in the ISSYS (Investigating Silent Strokes in hYpertensives: A magnetic resonance imaging Study).

PMID: 22836018
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2012
Reference: J Neurol Sci. 2012 Nov 15;322(1-2):79-81. doi: 10.1016/j.jns.2012.06.015. Epub 2012 Jul 24.
Impact factor: 2.353
Publication type: Paper in international publication
Authors: Riba, I, Jarca, C I, Mundet, X, Tovar, J L, Orfila, F, Nafria, C, Raga, A, Girona, A, Fernandez-Lara, P, Castane, X et al.
DOI: 10.1016/j.jns.2012.06.015

Cognitive Disturbances and Neuropsychological Changes after Surgical Treatment in a Cohort of 185 Patients with Idiopathic Normal Pressure Hydrocephalus.

PMID: 22382387
Journal: ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
Year: 2012
Reference: Arch Clin Neuropsychol. 2012 May;27(3):304-17. doi: 10.1093/arclin/acs002. Epub 2012 Mar 1.
Impact factor: 2.178
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.1093/arclin/acs002

Cognitive dysfunction in cirrhosis is associated with falls. A prospective study.

PMID: 22213000
Journal: HEPATOLOGY
Year: 2012
Reference: Hepatology. 2012 Jun;55(6):1922-30. doi: 10.1002/hep.25554. Epub 2012 Apr 4.
Impact factor: 11.665
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1002/hep.25554