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Rheumatology

The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.

At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.

Team

Mireia Barcelo Bru

Mireia Barcelo Bru

Predoctoral researcher
Rheumatology
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Mireia Lopez Corbeto

Mireia Lopez Corbeto

Main researcher
Rheumatology
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Sara Marsal Barril

Sara Marsal Barril

Main researcher
Rheumatology
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M Alba Erra Duran

M Alba Erra Duran

Postdoctoral researcher
Rheumatology
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Ramón Sanmartín Sentañes

Ramón Sanmartín Sentañes

Main researcher
Rheumatology
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Andrea Pluma Sanjurjo

Andrea Pluma Sanjurjo

Predoctoral researcher
Rheumatology
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Mireia Barcelo Bru

Mireia Barcelo Bru

Predoctoral researcher
Rheumatology
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Mireia Lopez Corbeto

Mireia Lopez Corbeto

Main researcher
Rheumatology
Read more
Sara Marsal Barril

Sara Marsal Barril

Main researcher
Rheumatology
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M Alba Erra Duran

M Alba Erra Duran

Postdoctoral researcher
Rheumatology
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Ramón Sanmartín Sentañes

Ramón Sanmartín Sentañes

Main researcher
Rheumatology
Read more
Andrea Pluma Sanjurjo

Andrea Pluma Sanjurjo

Predoctoral researcher
Rheumatology
Read more

Projects

Caracterización de las células patogénicas del músculo y piel de pacientes con Dermatomiositis y Síndrome Antisintetasa y estudio de aplicabilidad traslacional.

IP: Ernesto Trallero Araguas
Collaborators: Albert Selva O'Callaghan, Raul Tortosa Mendez, Albert Gil Vila, Gloria Aparicio Español, Adria Aterido Ballonga, Hugo Fernando Avalos Bogado
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI22/00708
Duration: 01/01/2023 - 31/12/2025

Ayudas para facultativos investigadores

IP: Sara Marsal Barril
Collaborators: Alejandro Gòmez Gomez, Miriam Izquierdo Sans, Judit Álvarez González
Funding agency: Fundación Española de Reumatología
Funding: 135000
Reference: FER/RECERCA/2021/MARSAL
Duration: 14/02/2022 - 13/02/2025

DECISION ON OPTIMAL COMBINATORIAL THERAPIES IN IMIDS USING SYSTEMS APPROACHES (DOCTIS)

IP: Sara Marsal Barril
Collaborators: Antonio Julia Cano, Javier Hoyo Pérez, Elena Granell Pallares, Adria Aterido Ballonga, Montse Sender Beleta, Nuria Palau Balaña, Edgar Nuñez Gallardo, Raul Tortosa Mendez, Maria Alba Erra Duran
Funding agency: EUROPEAN COMMISSION
Funding: 1079085
Reference: DOCTIS_H2020_SC1-BHC2019
Duration: 01/01/2020 - 31/12/2025

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (DISCOvERIE)

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez, Silvia Muñoz Caller, Carmen Alonso Cotoner, Ana Maria Gonzalez Castro, Elba Exposito Fernandez, Marc Pigrau Pastor, Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (D, Adoración Nieto Ruiz, Alejandro Henao Paez, Consuelo Cammarota, José Alegre Martin, Jesus Castro Marrero, Marta Ribases Haro, Natalia Llonga Tejedor, Amanda Rodríguez Urrutia
Funding agency: EUROPEAN COMMISSION
Funding: 1148684.84
Reference: DISCOVERIE_H2020-SC1-BHC2019
Duration: 01/01/2020 - 31/05/2025

Publications

Idiopathic inflammatory myopathy.

PMID: 39875256
Journal: MEDICINA CLINICA
Year: 2025
Reference: Med Clin (Barc). 2025 Jan 27:S0025-7753(25)00013-2. doi: 10.1016/j.medcli.2024.12.008.
Impact factor:
Publication type: Paper in international publication
Authors: Gil-Vila, Albert; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1016/j.medcli.2024.12.008

Simvastatin and Rifaximin in Decompensated Cirrhosis: A Randomized Clinical Trial.

PMID: 39908052
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2025
Reference: JAMA. 2025 Feb 5. doi: 10.1001/jama.2024.27441.
Impact factor:
Publication type: Paper in international publication
Authors: Abraldes, Juan G; Alessandria, Carlo; Allegretti, Andrew S; Alonso, Sonia; Angeli, Paolo; Ariza, Xavier; Banares, Rafael; Beuers, Ulrich; Campion, Daniela; Caraceni, Paolo et al.
DOI: 10.1001/jama.2024.27441

Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study.

PMID: 40058397
Journal: Lancet Gastroenterology & Hepatology
Year: 2025
Reference: Lancet Gastroenterol Hepatol. 2025 Mar 6:S2468-1253(25)00006-8. doi: 10.1016/S2468-1253(25)00006-8.
Impact factor:
Publication type: Paper in international publication
Authors: Abdelkader, Nadia Abdelaaty; Alessandria, Carlo; Allegretti, Andrew S; Angeli, Paolo; Arab, Juan Pablo; Asrani, Sumeet K; Balcar, Lorenz; Barone, Anna; Bruns, Tony; Cabrera, Maria Cecilia et al.
DOI: 10.1016/S2468-1253(25)00006-8

Real-world experience of IL-17Ai drug survival in a large cohort of axial spondyloarthritis and psoriatic arthritis.

PMID: 38435412
Journal:
Year: 2024
Reference: Rheumatol Adv Pract. 2024 Feb 15;8(1):rkae018. doi: 10.1093/rap/rkae018. eCollection 2024.
Impact factor:
Publication type: Paper in international publication
Authors: Barr, Andrew; Din, Naw Ra Aung; Freeston, Jane; Harrison, Stephanie R; Marzo-Ortega, Helena; McGonagle, Dennis; Michelena, Xabier; Vandevelde, Claire; Weddell, Jake et al.
DOI: 10.1093/rap/rkae018

Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study.

PMID: 38443140
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2024
Reference: Ann Rheum Dis. 2024 Mar 5:ard-2023-225443. doi: 10.1136/ard-2023-225443.
Impact factor:
Publication type: Paper in international publication
Authors: Becciolini, Andrea; Camarda, Federica; Cazenave, Tomas; Cipolletta, Edoardo; Corradini, Davide; de Agustin, Juan Jose; Destro Castaniti, Giulia Maria; Di Donato, Eleonora; Di Donato, Stefano; Di Geso, Luca et al.
DOI: 10.1136/ard-2023-225443

Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes.

PMID: 38468286
Journal: GENOME BIOLOGY
Year: 2024
Reference: Genome Biol. 2024 Mar 11;25(1):68. doi: 10.1186/s13059-024-03210-0.
Impact factor:
Publication type: Paper in international publication
Authors: Alperi-Lopez, Mercedes; Aterido, Adria; Blanco, Francisco; Byrne-Steele, Miranda; Erra, Alba; Fernandez-Cid, Carlos Marras; Fernandez-Nebro, Antonio; Garcia-Vivar, Maria Luz; Han, Jian; Juan-Mas, Antonio et al.
DOI: 10.1186/s13059-024-03210-0

Nailfold capillaroscopy findings of a multicentric multi-ethnic cohort of patients with idiopathic inflammatory myopathies.

PMID: 38488092
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2024
Reference: Clin Exp Rheumatol. 2024 Feb;42(2):367-376. doi: 10.55563/clinexprheumatol/l9gudh. Epub 2024 Mar 14.
Impact factor:
Publication type: Paper in international publication
Authors: Campbell, Bianca; Casal-Dominguez, Maria; Gil-Vila, Albert; Guillen-Del-Castillo, Alfredo; Mammen, Andrew Lee; Mejia-Dominguez, Nancy R; Milisenda, Jose; Munoz-Braceras, Sandra; Nunez-Alvarez, Carlos; Pak, Katherine et al.
DOI: 10.55563/clinexprheumatol/l9gudh

Direct Oral Anticoagulants vs Vitamin-K Antagonists in Thrombotic Antiphospholipid Syndrome: Meta-analysis of Randomized Controlled Trials.

PMID: 36328154
Journal: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Year: 2023
Reference: J Am Coll Cardiol. 2023 Jan 3;81(1):16-30. doi: 10.1016/j.jacc.2022.10.008. Epub 2022 Oct 31.
Impact factor:
Publication type: Paper in international publication
Authors: Bejjani, Antoine; Bikdeli, Behnood; Chatterjee, Saurav; Connors, Jean M; Cortes-Hernandez, Josefina; Cushman, Mary; Falanga, Anna; Garcia, David A; Goldhaber, Samuel Z; Jimenez, David et al.
DOI: 10.1016/j.jacc.2022.10.008

Therapeutic Response After Immunosuppressive Drug Prescription in Non-infectious Uveitis: A Survival Analysis.

PMID: 36266560
Journal: Ophthalmology and Therapy
Year: 2023
Reference: Ophthalmol Ther. 2023 Feb;12(1):139-153. doi: 10.1007/s40123-022-00587-8. Epub 2022 Oct 20.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Hernandez, Paula; Arriola-Villalobos, Pedro; Benitez Del Castillo, Jose M; Borrego-Sanz, Lara; Diaz-Valle, David; Gomez-Gomez, Alejandro; Madrid-Garcia, Alfredo; Mendez-Fernandez, Rosalia; Pato-Cour, Esperanza; Perez-Sancristobal, Ines et al.
DOI: 10.1007/s40123-022-00587-8

The ultrasonographic "pseudo-double contour" sign in calcium pyrophosphate deposition disease.

PMID: 36281790
Journal: Arthritis & Rheumatology
Year: 2023
Reference: Arthritis Rheumatol. 2023 Apr;75(4):639-640. doi: 10.1002/art.42397. Epub 2023 Feb 14.
Impact factor:
Publication type: Letter or abstract
Authors: Bong, David; Coronel, Luis; Filippou, Georgios; Miguel-Perez, Maribel; Moller, Ingrid; Pacini, Giovanni; Scanu, Anna; Sirotti, Silvia et al.
DOI: 10.1002/art.42397

Downregulation of miR-885-5p promotes NF-kappaB pathway activation and immune recruitment in Cutaneous Lupus Erythematosus.

PMID: 36049539
Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Year: 2023
Reference: J Invest Dermatol. 2023 Feb;143(2):209-219.e13. doi: 10.1016/j.jid.2022.08.036. Epub 2022 Aug 30.
Impact factor:
Publication type: Paper in international publication
Authors: Aparicio, Gloria; Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Penzo, Eleonora; Porres, Laura; Sole, Cristina et al.
DOI: 10.1016/j.jid.2022.08.036

When the usual doses are not enough.

PMID: 34774452
Journal: Reumatologia clinica
Year: 2022
Reference: Reumatol Clin (Engl Ed). 2022 Nov;18(9):560-561. doi: 10.1016/j.reumae.2021.05.001. Epub 2021 Nov 10.
Impact factor:
Publication type: Letter or abstract
Authors: Grados Canovas, Maria Dolors; Macias Reyes, Maria Jose; Marsal Barril, Sara; Pluma Sanjurjo, Andrea et al.
DOI: 10.1016/j.reumae.2021.05.001

An overlook on the current registries for rare and complex connective tissue diseases and the future scenario of TogethERN ReCONNET.

PMID: 36226147
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2022 Sep 26;9:889997. doi: 10.3389/fmed.2022.889997. eCollection 2022.
Impact factor:
Publication type: Review in international publication
Authors: Arnaud, Laurent; Bandeira, Matilde; Barril, Sara M; Bulina, Inita; Cannizzo, Sara; Carta, Claudio; Cornet, Alain; Cutolo, Maurizio; Di Cianni, Federica; Ferraris, Alessandro et al.
DOI: 10.3389/fmed.2022.889997

Management of Cancer-Associated Myositis.

PMID: 36313478
Journal: Current treatment options in rheumatology
Year: 2022
Reference: Curr Treatm Opt Rheumatol. 2022;8(4):91-104. doi: 10.1007/s40674-022-00197-2. Epub 2022 Oct 21.
Impact factor:
Publication type: Review in international publication
Authors: Agusti, Antonia; Alvarado-Cardenas, Marcelo; Gil-Vila, Albert; Lostes, Julia; Pinal-Fernandez, Iago; Riera-Arnau, Judit; Ros, Javier; Ros, Javier; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1007/s40674-022-00197-2

Effectiveness of two video-based multicomponent treatments for fibromyalgia: The added value of cognitive restructuring and mindfulness in a three-arm randomised controlled trial.

PMID: 36116229
Journal: BEHAVIOUR RESEARCH AND THERAPY
Year: 2022
Reference: Behav Res Ther. 2022 Nov;158:104188. doi: 10.1016/j.brat.2022.104188. Epub 2022 Sep 8.
Impact factor:
Publication type: Paper in international publication
Authors: Albajes, Klara; Almirall, Miriam; Feliu-Soler, Albert; Lluch Girbes, Enrique; Luciano, Juan V; Moix, Jenny; Navarrete, Jaime; Neblett, Randy; Serrat, Mayte et al.
DOI: 10.1016/j.brat.2022.104188

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

PMID: 34597274
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2021
Reference: J Clin Invest. 2021 Dec 1;131(23). pii: 152386. doi: 10.1172/JCI152386.
Impact factor:
Publication type: Paper in international publication
Authors: Aarberg Lund, Kristine Marie; Aarem, Jeanette; Aballi, Saad; Abdullah, Tala; Adeleye, Olumide; Adra, Darin; Afilalo, Jonathan; Afilalo, Marc; Afrasiabi, Zaman; Aghemo, Alessio et al.
DOI: 10.1172/JCI152386

IgG4-Related Disease, A Single-Center Experience.

PMID: 30585995
Journal: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
Year: 2021
Reference: J Clin Rheumatol. 2021 Dec 1;27(8S):S590-S591. doi: 10.1097/RHU.0000000000000970.
Impact factor:
Publication type: Letter whit IF
Authors: Barra, Lillian; Fernandez-Codina, Andreu; Haig, Sarah; Pope, Janet E et al.
DOI: 10.1097/RHU.0000000000000970

Thalidomide Exerts Anti-Inflammatory Effects in Cutaneous Lupus by Inhibiting the IRF4/NF-B and AMPK1/mTOR Pathways.

PMID: 34944673
Journal: Biomedicines
Year: 2021
Reference: Biomedicines. 2021 Dec 7;9(12). pii: biomedicines9121857. doi: 10.3390/biomedicines9121857.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Sole, Cristina et al.
DOI: 10.3390/biomedicines9121857

Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA: Different quasispecies?

PMID: 34887634
Journal: WORLD JOURNAL OF GASTROENTEROLOGY
Year: 2021
Reference: World J Gastroenterol. 2021 Nov 7;27(41):7144-7158. doi: 10.3748/wjg.v27.i41.7144.
Impact factor:
Publication type: Paper in international publication
Authors: Buti, Maria; Casillas, Rosario; Casis, Ernesto; Castillo-Ribelles, Laura; Cortese, Maria Francesca; Esteban, Rafael; Ferrer-Costa, Roser; Garcia-Garcia, Selene; Gregori, Josep; Pacin, Beatriz et al.
DOI: 10.3748/wjg.v27.i41.7144

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

PMID: 32341526
Journal: NATURE GENETICS
Year: 2020
Reference: Nat Genet. 2020 May;52(5):482-493. doi: 10.1038/s41588-020-0610-9. Epub 2020 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Adan, Roger; Agee, Michelle; Alfredsson, Lars; Alipanahi, Babak; Ando, Tetsuya; Andreassen, Ole; Anttila, Verneri; Arenas, Ernest; Artto, Ville; Auton, Adam et al.
DOI: 10.1038/s41588-020-0610-9

Expert Consensus on a Set of Outcomes to Assess the Effectiveness of Biologic Treatment in Psoriatic Arthritis: The MERECES Study.

PMID: 32007930
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2020
Reference: J Rheumatol. 2020 Nov 1;47(11):1637-1643. doi: 10.3899/jrheum.191056. Epub 2020 Feb 1.
Impact factor:
Publication type: Paper in international publication
Authors: Abad, Angel; Ahijado, Pilar; Almodovar, Raquel; Alonso, Elena; Alonso-Castro, Sara; Alvarez-Castro, Carolina; Alvarez-Vega, Jose L; Babio, Jesus; Batlle, Enrique; Belinchon, Isabel et al.
DOI: 10.3899/jrheum.191056

Are glomerular patients treated with immunosupressed drugs more protected against sever SARS-Covid -2?

PMID: 32994058
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2020
Reference: Semin Arthritis Rheum. 2020 Dec;50(6):e4. doi: 10.1016/j.semarthrit.2020.09.004. Epub 2020 Sep 22.
Impact factor:
Publication type: Letter or abstract
Authors: Agraz-Pamplona, Irene; Bolufer, Monica; Bury, Roxana; Carro, Clara Garcia; Cortes, Josefina; Espinel, Eugenia; Montoro, Bruno; Seron, Daniel; Solans, Roser; Soler, M Jose et al.
DOI: 10.1016/j.semarthrit.2020.09.004

Anti-TIF-1gamma Antibody Detection Using a Commercial Kit vs In-House Immunoblot: Usefulness in Clinical Practice.

PMID: 33613568
Journal: Frontiers in Immunology
Year: 2020
Reference: Front Immunol. 2021 Feb 1;11:625896. doi: 10.3389/fimmu.2020.625896. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Alserawan, Leticia; Alvarado-Cardenas, Marcelo; Baucells, Andres; Castellvi, Ivan; Corominas, Hector; Franco-Leyva, Teresa; Guillen, Andrea Garcia; Juarez, Candido; Mariscal, Anais; Martinez, Maria Angeles et al.
DOI: 10.3389/fimmu.2020.625896

PET Scan: Nuclear Medicine Imaging in Myositis.

PMID: 31754890
Journal: Current Rheumatology Reports
Year: 2019
Reference: Curr Rheumatol Rep. 2019 Nov 21;21(11):64. doi: 10.1007/s11926-019-0864-3.
Impact factor:
Publication type: Review in international publication
Authors: Alvarado-Cardenas, Marcelo; Gil-Vila, Albert; Pinal-Fernandez, Iago; Selva-O'Callaghan, Albert; Simo-Perdigo, Marc; Trallero-Araguas, Ernesto et al.
DOI: 10.1007/s11926-019-0864-3

Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course.

PMID: 31752231
Journal: Journal of Clinical Medicine
Year: 2019
Reference: J Clin Med. 2019 Nov 18;8(11). pii: jcm8112013. doi: 10.3390/jcm8112013.
Impact factor:
Publication type: Paper in international publication
Authors: Andersson, Helena; Arrigoni, Eugenio; Bachiller-Corral, Javier; Barsotti, Simone; Bartoloni, Elena; Bauhammer, Jutta; Bellando Randone, Silvia; Benucci, Maurizio; Blazquez Canamero, Maria Angeles; Bonella, Francesco et al.
DOI: 10.3390/jcm8112013

Withdrawal of infliximab therapy in ankylosing spondylitis in persistent clinical remission, results from the REMINEA study.

PMID: 30953541
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2019
Reference: Arthritis Res Ther. 2019 Apr 5;21(1):88. doi: 10.1186/s13075-019-1873-3.
Impact factor:
Publication type: Paper in international publication
Authors: Arasa, Xavier; Blanco, Jordi; Bonet, Maria; Centelles, Montse; Ciria, Manel; Clavaguera, Teresa; Figuls, Ramon; Gelman, Mario; Gratacos, Jordi; Hernandez, Victoria et al.
DOI: 10.1186/s13075-019-1873-3

Objectives and methodology of BIOBADASER phase iii.

PMID: 28935290
Journal: Reumatologia clinica
Year: 2019
Reference: Reumatol Clin. 2019 Jul - Aug;15(4):229-236. doi: 10.1016/j.reuma.2017.08.001. Epub 2017 Sep 19.
Impact factor:
Publication type: Paper in national publication
Authors: Barcelo Bru, Mireia; Bustabad, Sagrario; Campos, Cristina; Cuende, Eduardo; Del Pino-Montes, Javier; Diaz-Gonzalez, Federico; Farietta Varela, Sandra Myriam; Fernandez-Lopez, Jesus Carlos; Gomez-Reino, Juan Jesus; Grp Trabajo BIOBADASER Fase III et al.
DOI: 10.1016/j.reuma.2017.08.001

Analysis of shared heritability in common disorders of the brain.

PMID: 29930110
Journal: SCIENCE
Year: 2018
Reference: Science. 2018 Jun 22;360(6395). pii: 360/6395/eaap8757. doi: 10.1126/science.aap8757.
Impact factor:
Publication type: Paper in international publication
Authors: Adams, Hieab H H; Air, Tracy; Al-Chalabi, Ammar; Alda, Martin; Alegret, Montserrat; Alfredsson, Lars; Amouyel, Philippe; Andlauer, Till F M; Andreassen, Ole A; Anjorin, Adebayo et al.
DOI: 10.1126/science.aap8757

Low omega-3 index and polyunsaturated fatty acid status in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

PMID: 30471769
Journal: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
Year: 2018
Reference: Prostaglandins Leukot Essent Fatty Acids. 2018 Dec;139:20-24. doi: 10.1016/j.plefa.2018.11.006. Epub 2018 Nov 9.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Castro-Marrero, Jesus; Domingo, Joan Carles; Martinez-Martinez, Alba; von Schacky, Clemens; Zaragoza, Maria Cleofe et al.
DOI: 10.1016/j.plefa.2018.11.006

Persistence and adverse events of biological treatment in adult patients with juvenile idiopathic arthritis: results from BIOBADASER.

PMID: 30305158
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2018
Reference: Arthritis Res Ther. 2018 Oct 10;20(1):227. doi: 10.1186/s13075-018-1728-3.
Impact factor:
Publication type: Paper in international publication
Authors: Bethencourt Baute, Juan Jose; Bustabad Reyes, Sagrario; Campos, Cristina; Diaz-Gonzalez, Federico; Garcia-Gonzalez, Javier; Gomez-Reino, Juan Jesus; Hernandez, Victoria; Manrique, Sara; Medrano San Ildefonso, Marta; Ortiz, Ana et al.
DOI: 10.1186/s13075-018-1728-3

Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe-the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review.

PMID: 30181183
Journal: BMJ Open
Year: 2018
Reference: BMJ Open. 2018 Sep 4;8(9):e020817. doi: 10.1136/bmjopen-2017-020817.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Bakken, Inger Johanne; Capelli, Enrica; Castro-Marrero, Jesus; Estevez-Lopez, Fernando; Ivanovs, Andrejs; Lacerda, Eliana; Lorusso, Lorenzo; Murovska, Modra; Nacul, Luis et al.
DOI: 10.1136/bmjopen-2017-020817

Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib/IIa clinical trial.

PMID: 27269294
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2017
Reference: Ann Rheum Dis. 2017 Jan;76(1):196-202. doi: 10.1136/annrheumdis-2015-208918. Epub 2016 Jun 7.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Alberto; Alvaro-Gracia, Jose M; Blanco, Francisco; Carreno, Luis; DelaRosa, Olga; Diaz-Gonzalez, Federico; Garcia-Vicuna, Rosario; Jover, Juan A; Marsal, Sara; Martin-Martin, Cristina et al.
DOI: 10.1136/annrheumdis-2015-208918

Genetic variation associated with cardiovascular risk in autoimmune diseases.

PMID: 28982122
Journal: PLoS One
Year: 2017
Reference: PLoS One. 2017 Oct 5;12(10):e0185889. doi: 10.1371/journal.pone.0185889. eCollection 2017.
Impact factor:
Publication type: Paper in international publication
Authors: Aterido, Adria; Canete, Juan D; Corbeto, Mireia L; Domenech, Eugeni; Fernandez, Emilia; Fernandez-Gutierrez, Benjamin; Fernandez-Nebro, Antonio; Ferrandiz, Carlos; Garcia-Planella, Esther; Gisbert, Javier P et al.
DOI: 10.1371/journal.pone.0185889

Clinical utility of the ASDAS index in comparison with BASDAI in patients with ankylosing spondylitis (Axis Study).

PMID: 28918450
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2017
Reference: Rheumatol Int. 2017 Nov;37(11):1817-1823. doi: 10.1007/s00296-017-3814-2. Epub 2017 Sep 16.
Impact factor:
Publication type: Paper in international publication
Authors: Abad Hernandez, Miguel Angel; Alonso Ruiz, Alberto; Carrasco Benitez, Virginia; Collantes Estevez, Eduardo; Fisac, Cesar; Juanola Roura, Xavier; Medina Luezas, Julio; Rosas, Jose; Sellas I Fernandez, Agusti et al.
DOI: 10.1007/s00296-017-3814-2

The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE.

PMID: 28747192
Journal: Journal of Translational Medicine
Year: 2017
Reference: J Transl Med. 2017 Jul 26;15(1):162. doi: 10.1186/s12967-017-1263-z.
Impact factor:
Publication type: Review in national publication
Authors: Authier, Jerome; Blanco, Julia; Capelli, Enrica; Castro Marrero, Jesus; Freitag, Helma; Lacerda, Eliana; Meeus, Mira; Murovska, Modra; Nora-Krukle, Zaiga; Oltra, Elisa et al.
DOI: 10.1186/s12967-017-1263-z

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis.

PMID: 27716427
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2016
Reference: Arthritis Res Ther. 2016 Oct 4;18(1):221.
Impact factor:
Publication type: Paper in international publication
Authors: Balsa, Alejandro; Blanco, Francisco; Fernandez-Luna, Jose L; Fernandez-Nebro, Antonio; Julia, Antonio; Lopez-Hoyos, Marcos; Marsal, Sara; Martinez-Taboada, Victor; Munoz, Pedro; Torices, Silvia et al.
DOI: 10.1186/s13075-016-1113-z

Urine metabolome profiling of immune-mediated inflammatory diseases.

PMID: 27609333
Journal: BMC Medicine
Year: 2016
Reference: BMC Med. 2016 Sep 8;14(1):133. doi: 10.1186/s12916-016-0681-8.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre-Zamorano, MariaAngeles; Alonso, Arnald; Alperi-Lopez, Mercedes; Andreu, JoseLuis; Avila, Gabriela; Barreiro-de Acosta, Manuel; Beltran, Antoni; Blanco, Francisco; Blanco, Ricardo; Canete, Juan D et al.
DOI: 10.1186/s12916-016-0681-8

Zika virus infection in pregnant women in Barcelona, Spain.

PMID: 27063354
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2016
Reference: Clin Microbiol Infect. 2016 Jul;22(7):648-50. doi: 10.1016/j.cmi.2016.03.025. Epub 2016 Apr 6.
Impact factor:
Publication type: Paper in international publication
Authors: Bocanegra, C; Campins, M; Carreras, E; De Ory, F; Espasa, M; Llurba, E; Martin, A; Molina, I; Pou, D; Pumarola, T et al.
DOI: 10.1016/j.cmi.2016.03.025

Gender differences in chronic fatigue syndrome.

PMID: 26190206
Journal: Reumatologia clinica
Year: 2016
Reference: Reumatol Clin. 2016 Mar-Apr;12(2):72-77. doi: 10.1016/j.reuma.2015.05.007. Epub 2015 Jul 17.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Jose; Aliste, Luisa; Castro-Marrero, Jesus; Faro, Monica; Fernandez de Sevilla, Tomas; Saez-Francas, Naia et al.
DOI: 10.1016/j.reuma.2015.05.007

Intrapleural Fibrinolysis with Urokinase Versus Alteplase in Complicated Parapneumonic Pleural Effusions and Empyemas: A Prospective Randomized Study.

PMID: 26423784
Journal: LUNG
Year: 2015
Reference: Lung. 2015 Dec;193(6):993-1000. doi: 10.1007/s00408-015-9807-6. Epub 2015 Sep 30.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Aleman, Carmen; Andreu, Jordi; Bielsa, Silvia; Bruno Montoro, J; de Sevilla, Tomas Fernandez; Deu, Maria; Lopez, Iker; Martinez-Sogues, Mireia; Pallisa, Esther et al.
DOI: 10.1007/s00408-015-9807-6

Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.

PMID: 25848939
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Apr 7;10(4):e0122088. doi: 10.1371/journal.pone.0122088. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Alperiz, Mercedes; Aterido, Adria; Avila-Pedretti, Gabriela; Blanco, Francisco; Canete, Juan D; Corominas, Hector; Erra, Alba; Fernandez-Gutierrez, Benjamin; Fernandez-Nebro, Antonio; Gonzalez-Alvaro, Isidoro et al.
DOI: 10.1371/journal.pone.0122088

Analytical methods in untargeted metabolomics: state of the art in 2015.

PMID: 25798438
Journal: ANN ANIM SCI
Year: 2015
Reference: Front Bioeng Biotechnol. 2015 Mar 5;3:23. doi: 10.3389/fbioe.2015.00023. eCollection 2015.
Impact factor:
Publication type: Review in national publication
Authors: Alonso, Arnald; Julia, Antonio; Marsal, Sara et al.
DOI: 10.3389/fbioe.2015.00023

2014 update of the Consensus Statement of the Spanish Society of Rheumatology on the use of biological therapies in rheumatoid arthritis.

PMID: 26051464
Journal: Reumatologia clinica
Year: 2015
Reference: Reumatol Clin. 2015 Sep-Oct;11(5):279-294. doi: 10.1016/j.reuma.2015.05.001. Epub 2015 Jun 6.
Impact factor:
Publication type: Paper in international publication
Authors: Alvaro-Gracia, Jose Maria; Andreu, Jose Luis; Balsa, Alejandro; Caliz, Rafael; Fernandez-Nebro, Antonio; Ferraz-Amaro, Ivan; Garcia-Rodriguez, Susana; Gomez-Reino, Juan Jesus; Gonzalez-Alvaro, Isidoro; Marsal, Sara et al.
DOI: 10.1016/j.reuma.2015.05.001

Atypical scleromyxedema with prominent nodular lesions associated with immune thrombocytopenia: an unusual presentation.

PMID: 25219747
Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Year: 2014
Reference: J Am Acad Dermatol. 2014 Oct;71(4):e158-9. doi: 10.1016/j.jaad.2014.07.004.
Impact factor:
Publication type: Letter or abstract
Authors: Fernandez-Codina, Andreu; Ferrer, Berta; Garcia-Patos, Vicente; Hilari, Helena; Lopez-Lerma, Ingrid; Selva-O'Callaghan, Albert et al.
DOI: 10.1016/j.jaad.2014.07.004

The Pathogenesis and Genetics of Psoriasis.

PMID: 23369832
Journal: Actas dermo-sifiliograficas
Year: 2014
Reference: Actas Dermosifiliogr. 2014 Jul-Aug;105(6):535-45. doi: 10.1016/j.ad.2012.11.006. Epub 2013 Jan 29.
Impact factor:
Publication type: Review in national publication
Authors: Julia, A; Marsal, S; Puig, L et al.
DOI: 10.1016/j.ad.2012.11.006

"Pregnancy in adult-onset idiopathic inflammatory myopathy": report from a cohort of myositis patients from a single center.

PMID: 24906908
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2014
Reference: Semin Arthritis Rheum. 2014 Oct;44(2):234-40. doi: 10.1016/j.semarthrit.2014.05.004. Epub 2014 May 9.
Impact factor:
Publication type: Paper in international publication
Authors: Fernandez-Codina, Andreu; Martinez-Gomez, Xavier; Perez-Lopez, Jordi; Pinal-Fernandez, Iago; Rodrigo-Pendas, Jose; Selva-O'Callaghan, Albert; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.semarthrit.2014.05.004

Genome-wide analysis of single nucleotide polymorphisms and copy number variants in fibromyalgia suggest a role for the central nervous system.

PMID: 24582949
Journal: PAIN
Year: 2014
Reference: Pain. 2014 Jun;155(6):1102-9. doi: 10.1016/j.pain.2014.02.016. Epub 2014 Feb 26.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Carbonell, Jordi; Collado, Antonio; Docampo, Elisa; Escaramis, Georgia; Estivill, Xavier; Gratacos, Monica; Kogevinas, Manolis; Puig, Anna; Rabionet, Raquel et al.
DOI: 10.1016/j.pain.2014.02.016

The genetic architecture of rheumatoid arthritis: from susceptibility to clinical subphenotype associations.

PMID: 23574521
Journal: CURRENT TOPICS IN MEDICINAL CHEMISTRY
Year: 2013
Reference: Curr Top Med Chem. 2013;13(6):720-31.
Impact factor:
Publication type: Paper in international publication
Authors: Julia, Antonio; Marsal, Sara et al.
DOI:

GStream: improving SNP and CNV coverage on genome-wide association studies.

PMID: 23844243
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Jul 3;8(7):e68822. doi: 10.1371/journal.pone.0068822. Print 2013.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Arnald; Canela-Xandri, Oriol; Julia, Antonio; Marsal, Sara; Tortosa, Raul et al.
DOI: 10.1371/journal.pone.0068822

The role of neuroticism, perfectionism and depression in chronic fatigue syndrome. A structural equation modeling approach.

PMID: 23759150
Journal: COMPREHENSIVE PSYCHIATRY
Year: 2013
Reference: Compr Psychiatry. 2013 Oct;54(7):1061-7. doi: 10.1016/j.comppsych.2013.04.015. Epub 2013 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Calvo, Natalia; Casas, Miquel; Saez-Francas, Naia; Valero, Sergi et al.
DOI: 10.1016/j.comppsych.2013.04.015

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity.

PMID: 23249956
Journal: EUROPEAN JOURNAL OF HUMAN GENETICS
Year: 2013
Reference: Eur J Hum Genet. 2013 Jun;21(6):659-65. doi: 10.1038/ejhg.2012.229. Epub 2012 Dec 19.
Impact factor:
Publication type: Paper in international publication
Authors: Antonarakis, Stylianos E; Ausrele Kucinskiene, Zita; Borel, Christelle; D'Adamo, Pio; Debniak, Tadeusz; Esko, Tonu; Estivill, Xavier; Gasparini, Paolo; Glavac, Damjan; Gut, Ivo et al.
DOI: 10.1038/ejhg.2012.229

Unveiling Case-Control Relationships in Designing a Simple and Powerful Method for Detecting Gene-Gene Interactions.

PMID: 22886951
Journal: GENETIC EPIDEMIOLOGY
Year: 2012
Reference: Genet Epidemiol. 2012 Nov;36(7):710-6. doi: 10.1002/gepi.21665. Epub 2012 Aug 7.
Impact factor:
Publication type: Paper in international publication
Authors: Canela-Xandri, Oriol; Gelpi, Josep Lluis; Julia, Antonio; Marsal, Sara et al.
DOI: 10.1002/gepi.21665

Systemic lupus erythematosus: genomics, mechanisms, and therapies.

PMID: 22844327
Journal: Clinical & Developmental Immunology
Year: 2012
Reference: Clin Dev Immunol. 2012;2012:926931. Epub 2012 Jul 16.
Impact factor:
Publication type: Editorail in international publication
Authors: Chatham, Winn; Fernandez-Nebro, Antonio; Marsal, Sara; Rahman, Anisur et al.
DOI: 10.1155/2012/926931

Risk Variants for Psoriasis Vulgaris in a Large Case-Control Collection and Association with Clinical Subphenotypes.

PMID: 22814393
Journal: HUMAN MOLECULAR GENETICS
Year: 2012
Reference: Hum Mol Genet. 2012 Oct 15;21(20):4549-57. Epub 2012 Jul 19.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Acosta, Isabel; Alonso, Arnald; Canete, Juan D; Dauden, Esteban; Erra, Alba; Fernandez-Nebro, Antonio; Fernandez-Sueiro, Jose Luis; Ferrandiz, Carlos; Fonseca, Eduardo et al.
DOI: 10.1093/hmg/dds295

Attention-deficit hyperactivity disorder in chronic fatigue syndrome patients.

PMID: 22648008
Journal: PSYCHIATRY RESEARCH
Year: 2012
Reference: Psychiatry Res. 2012 Dec 30;200(2-3):748-53. doi: 10.1016/j.psychres.2012.04.041. Epub 2012 May 28.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.psychres.2012.04.041

[Chronic fatigue syndrome: study of a consecutive series of 824 cases assessed in two specialized units.]

PMID: 21794854
Journal: REVISTA CLINICA ESPANOLA
Year: 2011
Reference: Rev Clin Esp. 2011 Sep;211(8):385-90. Epub 2011 Jul 27.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.rce.2011.02.013

Enhanced transcript levels of CD48 in CD4(+) T cells from systemic lupus erythematosus patients.

PMID: 21474199
Journal: IMMUNOBIOLOGY
Year: 2011
Reference: Immunobiology. 2011 Sep;216(9):1034-7. Epub 2011 Mar 12.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.imbio.2011.03.004

[Anti-synthetase syndrome.]

PMID: 21543090
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Jun 11;137(2):77-83. Epub 2011 May 4.
Impact factor:
Publication type: Editorial in national publication
Authors: ; ; et al.
DOI: 10.1016/j.medcli.2011.02.026

Synovial fibroblast hyperplasia in rheumatoid arthritis: Clinicopathological correlations and partial reversal by anti-tumor necrosis factor therapy.

PMID: 21547893
Journal: ARTHRITIS AND RHEUMATISM
Year: 2011
Reference: Arthritis Rheum. 2011 Sep;63(9):2575-83. doi: 10.1002/art.30433.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1002/art.30433

Incidence and risk of hospitalisation due to shingles and chickenpox in patients with rheumatic diseases treated with TNF antagonists.

PMID: 20551153
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2010
Reference: Ann Rheum Dis. 2010 Oct;69(10):1751-5. Epub 2010 Jun 15.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Fred; Barcelo, Mireia; Beltran, Chesus; Borras, Juan Jose Garcia; Calvo, Javier; Campos, Cristina; Canete, Juan D; Cano, Laura; Carmona, Loreto; Cebrian, Laura et al.
DOI: 10.1136/ard.2009.125658

[Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome]

PMID: 20447621
Journal: REVISTA CLINICA ESPANOLA
Year: 2010
Reference: Rev Clin Esp. 2010 Jun;210(6):284-8. Epub 2010 May 5.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, J; de Sevilla, T Fernandez; Javierre, C; Roses, J M; Ruiz-Baques, A; Segundo, M J et al.
DOI: 10.1016/j.rce.2009.09.015

Conventional cancer screening versus PET/CT in dermatomyositis/polymyositis.

PMID: 20569766
Journal: AMERICAN JOURNAL OF MEDICINE
Year: 2010
Reference: Am J Med. 2010 Jun;123(6):558-62.
Impact factor:
Publication type: Paper in international publication
Authors: Andia-Navarro, Eduard; Gamez-Cenzano, Cristina; Grau, Josep M; Martinez-Gomez, Xavier; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vidaller-Palacin, Antonio; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.amjmed.2009.11.012

Long-term outcomes--mycophenolate mofetil treatment for lupus nephritis with addition of tacrolimus for resistant cases.

PMID: 20538787
Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION
Year: 2010
Reference: Nephrol Dial Transplant. 2010 Dec;25(12):3939-48. Epub 2010 Jun 10.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1093/ndt/gfq322

Genetic structure of Europeans: a view from the North-East.

PMID: 19424496
Journal: PLoS One
Year: 2009
Reference: PLoS One. 2009;4(5):e5472.
Impact factor:
Publication type: Letter or abstract
Authors: Antonarakis, Stylianos E; Attar, Homa; Balascak, Ivan; Borel, Christelle; D'Adamo, Pio; Debniak, Tadeusz; Deutsch, Samuel; Esko, Tonu; Estivill, Xavier; Gagnebin, Maryline et al.
DOI: 10.1371/journal.pone.0005472

Randomized clinical trial of the effectiveness of a home-based intervention in patients with heart failure: the IC-DOM study.

PMID: 19401125
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2009
Reference: Rev Esp Cardiol. 2009 Apr;62(4):400-8.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Jose; Ballarin, Elena; Brotons, Carlos; Casanovas, Jordi; Cata, Teresa; Falces, Carles; Martinez, Mireia; Moral, Irene; Ortiz, Jacint; Perez, Eulalia et al.
DOI:

Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.

PMID: 18495732
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2009
Reference: Ann Rheum Dis. 2009 May;68(5):751-6.
Impact factor:
Publication type: Paper in international publication
Authors: Canete, J D; Celis, R; de la Cruz, J; Izquierdo, E; Lora, D; Marsal, S; Moll, C; Pablos, J L; Palacin, A; Sanmarti, R et al.
DOI: 10.1136/ard.2008.089284

Anti-cyclic citrullinated peptide and anti-keratin antibodies in patients with idiopathic inflammatory myopathy.

PMID: 19386818
Journal: RHEUMATOLOGY
Year: 2009
Reference: Rheumatology (Oxford). 2009 Jun;48(6):676-9.
Impact factor:
Publication type: Paper in international publication
Authors: Delgado, Juan Francisco; Labrador-Horrillo, Moises; Martinez, Ma Angeles; Martinez-Gomez, Xavier; Rodriguez-Sanchez, Jose Luis; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI: 10.1093/rheumatology/kep065

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Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs

The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.

It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.