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Rheumatology

The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.

At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.

Team

Anna Roig Izquierdo

Anna Roig Izquierdo

Research assistant
Rheumatology
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Helena Borrell Paños

Helena Borrell Paños

Predoctoral researcher
Rheumatology
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Maria Pascual Pastor

Maria Pascual Pastor

Predoctoral researcher
Rheumatology
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Aitor Ruiz Ortiz

Aitor Ruiz Ortiz

Research technician
Rheumatology
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Estefania Moreno Ruzafa

Estefania Moreno Ruzafa

Research technician
Rheumatology
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Marta Muste Diaz

Marta Muste Diaz

Rheumatology
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Anna Roig Izquierdo

Anna Roig Izquierdo

Research assistant
Rheumatology
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Helena Borrell Paños

Helena Borrell Paños

Predoctoral researcher
Rheumatology
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Maria Pascual Pastor

Maria Pascual Pastor

Predoctoral researcher
Rheumatology
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Aitor Ruiz Ortiz

Aitor Ruiz Ortiz

Research technician
Rheumatology
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Estefania Moreno Ruzafa

Estefania Moreno Ruzafa

Research technician
Rheumatology
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Marta Muste Diaz

Marta Muste Diaz

Rheumatology
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Projects

Estratificación de pacientes con artritis reumatoide en la terapia anti-TNF. Caracterización espacial del transcriptoma de la membrana sinovial asociada a la respuesta a tratamiento y asociación a biomarcadores proteómicos.

IP: Antonio Julia Cano
Collaborators: Juan Jose De Agustin De Oro, Nuria Palau Balaña, Adria Aterido Ballonga
Funding agency: Instituto de Salud Carlos III
Funding: 196020
Reference: PI21/01185
Duration: 01/01/2022 - 30/06/2026

Novel therapeutic topical approach for discoid lupus cutaneous (DLE) treatment

IP: Cristina Solé Marce
Collaborators: Berta Ferrer Fábrega, Gloria Aparicio Español
Funding agency: Instituto de Salud Carlos III
Funding: 99099
Reference: PI21/01869
Duration: 01/01/2022 - 31/12/2025

Publications

Subclinical myocardial involvement in a cohort of patients with antisynthetase syndrome.

PMID: 38488096
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2024
Reference: Clin Exp Rheumatol. 2024 Feb;42(2):309-315. doi: 10.55563/clinexprheumatol/tgcrtf. Epub 2024 Mar 14.
Impact factor:
Publication type: Paper in international publication
Authors: Burcet-Rodriguez, Gemma; Cuellar-Calabria, Hug; Gil-Vila, Albert; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.55563/clinexprheumatol/tgcrtf

Restrictive Diets in Patients with Fibromyalgia: State of the Art.

PMID: 38540241
Journal: Biomedicines
Year: 2024
Reference: Biomedicines. 2024 Mar 12;12(3):629. doi: 10.3390/biomedicines12030629.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Espartal, Esther; Marsal, Sara; Muste, Marta; Serrat, Mayte; Tourino, Rafael et al.
DOI: 10.3390/biomedicines12030629

Study protocol for a three-arm randomized controlled trial investigating the effectiveness, cost-utility, and physiological effects of a fully self-guided digital Acceptance and Commitment Therapy for Spanish patients with fibromyalgia.

PMID: 38550263
Journal: Digital Health
Year: 2024
Reference: Digit Health. 2024 Mar 27;10:20552076241239177. doi: 10.1177/20552076241239177. eCollection 2024 Jan-Dec.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Borras, Xavier; D'Amico, Francesco; Dai, Yifei; Esteve, Montserrat; Feliu-Soler, Albert; Gallego, Ana; Grasa, Mar; Luciano, Juan V; McCracken, Lance M et al.
DOI: 10.1177/20552076241239177

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study.

PMID: 38600563
Journal: Journal of Translational Medicine
Year: 2024
Reference: J Transl Med. 2024 Apr 10;22(1):343. doi: 10.1186/s12967-024-05148-0.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre-Martin, Jose; Battistini, Federica; Cambras, Trinitat; Castro-Marrero, Jesus; Cordobilla, Begona; Domingo, Joan Carles; Sanmartin-Sentanes, Ramon; Zaragoza, Maria Cleofe et al.
DOI: 10.1186/s12967-024-05148-0

Prevalence of non-celiac gluten sensitivity and assessment of the response to gluten-free diet in a cohort of patients with fibromyalgia.

PMID: 35900154
Journal: RHEUMATOLOGY
Year: 2023
Reference: Rheumatology (Oxford). 2023 Mar 1;62(3):1069-1077. doi: 10.1093/rheumatology/keac434.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Casellas, Francesc; de Torres, Ines; Dot, Joan; Marsal S, Sara; Segurola, Hegoi et al.
DOI: 10.1093/rheumatology/keac434

High incidence of clinical fragility fractures in postmenopausal women with rheumatoid arthritis. A case-control study.

PMID: 36584785
Journal: BONE
Year: 2023
Reference: Bone. 2023 Mar;168:116654. doi: 10.1016/j.bone.2022.116654. Epub 2022 Dec 28.
Impact factor:
Publication type: Paper in international publication
Authors: Acin, Pilar Aguado; Arboleya, Luis; Armangue, Xavier Suris; Audera, Chesus Beltran; Bruno, Soledad Ojeda; Calleja, Cristina Hidalgo; Carazo, Sara Garcia; Castaneda, Santos; Castellanos-Moreira, Raul; Cerda, Dacia et al.
DOI: 10.1016/j.bone.2022.116654

Development of an algorithm for IgG4-related disease management.

PMID: 36682575
Journal: AUTOIMMUNITY REVIEWS
Year: 2023
Reference: Autoimmun Rev. 2023 Mar;22(3):103273. doi: 10.1016/j.autrev.2023.103273. Epub 2023 Jan 20.
Impact factor:
Publication type: Review in international publication
Authors: Culver, Emma L; D'Cruz, David P; Ebbo, Mikael; Fernandez-Codina, Andreu; Lanzillotta, Marco; Martinez-Valle, Fernando; Orozco-Galvez, Olimpia; Rebours, Vinciane; Schleinitz, Nicolas; Torre, Emanuel Della et al.
DOI: 10.1016/j.autrev.2023.103273

Coordinated local RNA overexpression of complement induced by interferon gamma in myositis.

PMID: 36739295
Journal: Scientific Reports
Year: 2023
Reference: Sci Rep. 2023 Feb 4;13(1):2038. doi: 10.1038/s41598-023-28838-z.
Impact factor:
Publication type: Paper in international publication
Authors: Albayda, Jemima; Casal-Dominguez, Maria; Christopher-Stine, Lisa; Corse, Andrea; Dell Orso, Stefania; Duque-Jaimez, Yaiza; Garrabou, Gloria; Grau, Josep Maria; Gutierrez-Cruz, Gustavo; Lloyd, Thomas E et al.
DOI: 10.1038/s41598-023-28838-z

Implementation of anti-HDV reflex testing among HBsAg-positive individuals increases testing for hepatitis D.

PMID: 36052219
Journal: JHEP Reports
Year: 2022
Reference: JHEP Rep. 2022 Jul 21;4(10):100547. doi: 10.1016/j.jhepr.2022.100547. eCollection 2022 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Pacin, Beatriz; Palom, Adriana; Rando-Segura, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Vargas, Elena; Vico, Judit et al.
DOI: 10.1016/j.jhepr.2022.100547

Humoral and cellular response in convalescent COVID-19 lupus patients.

PMID: 35962159
Journal: Scientific Reports
Year: 2022
Reference: Sci Rep. 2022 Aug 12;12(1):13787. doi: 10.1038/s41598-022-17334-5.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Sole, Cristina; Vidal, Xavier et al.
DOI: 10.1038/s41598-022-17334-5

Ultrasound in the evaluation of rheumatoid arthritis.

PMID: 35943461
Journal: European journal of rheumatology
Year: 2022
Reference: Eur J Rheumatol. 2022 Aug 9. doi: 10.5152/eurjrheum.2022.20224.
Impact factor:
Publication type: Paper in international publication
Authors: de Agustin de Oro, Juan Jose; Fernandez, Andres Ponce; Segarra, Vicente Torrente; Soria, Lourdes Mateo et al.
DOI: 10.5152/eurjrheum.2022.20224

Ultrasound in pediatric rheumatology: Highlighting the differences with adults.

PMID: 35943455
Journal: European journal of rheumatology
Year: 2022
Reference: Eur J Rheumatol. 2022 Mar 11;11(3):S348-S357. doi: 10.5152/eujrheum.2022.21119.
Impact factor:
Publication type: Paper in international publication
Authors: Lopez-Corbeto, Mireia; Moreno-Ruzafa, Estefania; Quesada-Masachs, Estefania et al.
DOI: 10.5152/eujrheum.2022.21119

A young girl with severe polyarteritis nodosa successfully treated with tocilizumab: a case report.

PMID: 34861842
Journal: Pediatric Rheumatology
Year: 2021
Reference: Pediatr Rheumatol Online J. 2021 Dec 3;19(1):168. doi: 10.1186/s12969-021-00654-7.
Impact factor:
Publication type: Letter or abstract
Authors: Aeschlimann, Florence A; Berbel Arcobe, Laura; Boistault, Margaux; Carsi Durall, Ariadna; Lopez Corbeto, Mireia; Quartier, Pierre et al.
DOI: 10.1186/s12969-021-00654-7

Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome.

PMID: 34799647
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Nov 19;11(1):22574. doi: 10.1038/s41598-021-01992-y.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Moralejo, Rodrigo; Atienza-Mateo, Belen; Balsa, Alejandro; Berastegui, Cristina; Bonilla, Gema; Calvo-Alen, Jaime; Castaneda, Santos; Cavagna, Lorenzo; Cifrian, Jose M; Diez, Elvira et al.
DOI: 10.1038/s41598-021-01992-y

Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.

PMID: 34732895
Journal: NATURE
Year: 2021
Reference: Nature. 2021 Nov;599(7886):673-678. doi: 10.1038/s41586-021-04057-2. Epub 2021 Nov 3.
Impact factor:
Publication type: Paper in international publication
Authors: An, Zhiqiang; Banik, Debarati; Berry, Deborah; Blommaert, Eline; Brantner, Christine A; Chaldekas, Krysta; Chiang, Huai-Chin; Curiel, Tyler J; Deng, Hui; Garcia, Roderic Espin et al.
DOI: 10.1038/s41586-021-04057-2

Efficacy of the FIBROWALK Multicomponent Program Moved to a Virtual Setting for Patients with Fibromyalgia during the COVID-19 Pandemic: A Proof-of-Concept RCT Performed Alongside the State of Alarm in Spain.

PMID: 34639600
Journal: International Journal of Environmental Research and Public Health
Year: 2021
Reference: Int J Environ Res Public Health. 2021 Sep 30;18(19). pii: ijerph181910300. doi: 10.3390/ijerph181910300.
Impact factor:
Publication type: Paper in international publication
Authors: Albajes, Klara; Almirall, Miriam; Coll-Omana, Mireia; Feliu-Soler, Albert; Luciano, Juan V; Serrat, Mayte; Sole, Silvia et al.
DOI: 10.3390/ijerph181910300

Association of apolipoprotein B/apolipoprotein A1 ratio and cardiovascular events in rheumatoid arthritis: results of the CARMA study.

PMID: 31694752
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2020
Reference: Clin Exp Rheumatol. 2020 Jul-Aug;38(4):662-669. Epub 2019 Oct 30.
Impact factor:
Publication type: Paper in international publication
Authors: Avila, Gabriela; Bachiller Corral, Javier; Barril, Sara Marçal; Bonilla Hernan, Gema; Castaneda, Santos; Delgado Frias, Esmeralda; Delgado Sanchez, Monica; Garcia Gonzalez, Javier; Garcia-Gomez, Carmen; Gonzalez-Gay, Miguel Angel et al.
DOI:

Effects of neuro-adaptive electrostimulation therapy on pain and disability in fibromyalgia: A prospective, randomized, double-blind study.

PMID: 33371148
Journal: MEDICINE
Year: 2020
Reference: Medicine (Baltimore). 2020 Dec 18;99(51):e23785. doi: 10.1097/MD.0000000000023785.
Impact factor:
Publication type: Paper in international publication
Authors: Alguacil-Diego, Isabel Maria; Castro-Marrero, Jesus; Cuenca-Zaldivar, Juan Nicolas; Fernandez-Carnero, Josue; Romano, Alberto Arribas; Udina-Cortes, Carlos; Villafane, Jorge Hugo et al.
DOI: 10.1097/MD.0000000000023785

Impact of Long-Term Cryopreservation on Blood Immune Cell Markers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for Biomarker Discovery.

PMID: 33329554
Journal: Frontiers in Immunology
Year: 2020
Reference: Front Immunol. 2020 Nov 17;11:582330. doi: 10.3389/fimmu.2020.582330. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Blanco, Julia; Cabrera, Cecilia; Carrillo, Jorge; Castro-Marrero, Jesus; Gomez-Mora, Elisabet; Oltra, Elisa; Rigau, Josepa; Urrea, Victor et al.
DOI: 10.3389/fimmu.2020.582330

MicroRNAs in Several Cutaneous Autoimmune Diseases: Psoriasis, Cutaneous Lupus Erythematosus and Atopic Dermatitis.

PMID: 33321931
Journal: Cells
Year: 2020
Reference: Cells. 2020 Dec 10;9(12). pii: cells9122656. doi: 10.3390/cells9122656.
Impact factor:
Publication type: Review in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Sole, Cristina et al.
DOI: 10.3390/cells9122656

Malignancy and myositis, from molecular mimicry to tumor infiltrating lymphocytes.

PMID: 31635909
Journal: NEUROMUSCULAR DISORDERS
Year: 2019
Reference: Neuromuscul Disord. 2019 Nov;29(11):819-825. doi: 10.1016/j.nmd.2019.09.014. Epub 2019 Sep 26.
Impact factor:
Publication type: Review in international publication
Authors: Gil-Vila, Albert; Pinal-Fernandez, Iago; Ros, Javier; Ros, Javier; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vila-Pijoan, Gemma et al.
DOI: 10.1016/j.nmd.2019.09.014

Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial.

PMID: 31610549
Journal: ANNALS OF INTERNAL MEDICINE
Year: 2019
Reference: Ann Intern Med. 2019 Nov 19;171(10):685-694. doi: 10.7326/M19-0291. Epub 2019 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Salomo, Antoni; Cortes-Hernandez, Josefina; Cuquet-Pedragosa, Jordi; Mauri-Plana, Montserrat; Ordi-Ros, Josep; Ortiz-Santamaria, Vera; Perez-Conesa, Mercedes; Riera-Mestre, Antoni; Saez-Comet, Luis; Sole, Cristina et al.
DOI: 10.7326/M19-0291

Functional rare variants influence the clinical response to anti-TNF therapy in Crohn's disease.

PMID: 31598133
Journal: Therapeutic Advances in Gastroenterology
Year: 2019
Reference: Therap Adv Gastroenterol. 2019 Sep 25;12:1756284819867848. doi: 10.1177/1756284819867848. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Melero, Patricia; Aterido, Adria; Banales, Jesus Maria; Barreiro-de Acosta, Manuel; Beltran, Belen; Benitez Garcia, Beatriz; Bermejo, Fernando; Bernardo, David; Blazquez Gomez, Isabel; Bujanda, Luis et al.
DOI: 10.1177/1756284819867848

Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis.

PMID: 30621746
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2019
Reference: Arthritis Res Ther. 2019 Jan 8;21(1):11. doi: 10.1186/s13075-018-1772-z.
Impact factor:
Publication type: Paper in international publication
Authors: Albinana, Nestor; Almirall, Miriam; Aparicio, Maria; Ariza, Rafael; Avendano, Cristina; Batlle, Enrique; Calvo, Gonzalo; Campos, Cristina; Clavaguera, Teresa; Collantes, Eduardo et al.
DOI: 10.1186/s13075-018-1772-z

Classification and management of adult inflammatory myopathies.

PMID: 30129477
Journal: LANCET NEUROLOGY
Year: 2018
Reference: Lancet Neurol. 2018 Sep;17(9):816-828. doi: 10.1016/S1474-4422(18)30254-0.
Impact factor:
Publication type: Review in international publication
Authors: Grau-Junyent, Josep Maria; Mammen, Andrew L; Milisenda, Jose Cesar; Pinal-Fernandez, Iago; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1016/S1474-4422(18)30254-0

Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure who reach complete response after rescue treatment.

PMID: 30129233
Journal: HEMATOLOGICAL ONCOLOGY
Year: 2018
Reference: Hematol Oncol. 2018 Dec;36(5):765-772. doi: 10.1002/hon.2553. Epub 2018 Sep 12.
Impact factor:
Publication type: Paper in international publication
Authors: Albo, Carmen; Arranz, Reyes; Bobillo, Sabella; Caballero, Dolores; Coria, Erika; Ferreiro, Jose Javier; Galeo, Andrea; Grande, Carlos; Hernandez-Garcia, Miguel Teodoro; Jarque, Isidro et al.
DOI: 10.1002/hon.2553

Dimensional Personality Assessment among a Chronic Fatigue Syndrome (CFS) sample with Personality Inventory for DSM-5 (PID-5).

PMID: 30079926
Journal: ACTAS ESPANOLAS DE PSIQUIATRIA
Year: 2018
Reference: Actas Esp Psiquiatr. 2018 Jul;46(4):125-32. Epub 2018 Jul 1.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Jose; Calvo, Natalia; Casas, Miquel; Castro-Marrero, Jesus; Ferrer, Marc; Gutierrez, Fernando; Pueyo, Natalia; Ramos Quiroga, Josep-Antoni; Saez-Francas, Naia et al.
DOI:

Subclinical cardiovascular disease and Systemic Sclerosis: A comparison between risk charts, quantification of coronary calcium and carotid ultrasonography.

PMID: 30005858
Journal: AUTOIMMUNITY REVIEWS
Year: 2018
Reference: Autoimmun Rev. 2018 Sep;17(9):900-905. doi: 10.1016/j.autrev.2018.03.015. Epub 2018 Jul 11.
Impact factor:
Publication type: Review in national publication
Authors: Callejas Moragas, E; Cuellar Calabria, H; Fernandez Codina, A; Fonollosa Pla, V; Guillen Del Castillo, A; Martinez Valle, F; Orozco Galvez, O; Pizzi, M N; Roque Perez, A; Sanz Perez, I et al.
DOI: 10.1016/j.autrev.2018.03.015

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts.

PMID: 28658137
Journal: MEDICINE
Year: 2017
Reference: Medicine (Baltimore). 2017 Jun;96(26):e7308. doi: 10.1097/MD.0000000000007308.
Impact factor:
Publication type: Paper in international publication
Authors: Blanco, Francisco; Canete, Juan D; Carreira, Patricia; Domenech, Eugeni; Fernandez-Gutierrez, Benjamin; Fernandez-Nebro, Antonio; Ferrandiz, Carlos; Fonseca, Eduardo; Garcia-Sanchez, Valle; Gisbert, Javier P et al.
DOI: 10.1097/MD.0000000000007308

Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus.

PMID: 28619073
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2017
Reference: Arthritis Res Ther. 2017 Jun 15;19(1):138. doi: 10.1186/s13075-017-1345-6.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Aguirre-Zamorano, Maria Angeles; Andreu, Jose Luis; Aterido, Adria; Blanco, Ricardo; Carreira, Patricia; Diez, Elvira; Fernandez-Nebro, Antonio; Freire, Mercedes; Gelpi, Josep Lluis et al.
DOI: 10.1186/s13075-017-1345-6

Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study.

PMID: 28596045
Journal: PSYCHOSOMATICS
Year: 2017
Reference: Psychosomatics. 2017 Sep - Oct;58(5):533-543. doi: 10.1016/j.psym.2017.04.010. Epub 2017 Apr 21.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Aliste, Luisa; Calvo, Natalia; Castro-Marrero, Jesus; de Sevilla, Tomas Fernandez; Faro, Monica; Martinez-Martinez, Alba; Saez-Francas, Naia et al.
DOI: 10.1016/j.psym.2017.04.010

Epigenome-wide association study of rheumatoid arthritis identifies differentially methylated loci in B cells.

PMID: 28475762
Journal: HUMAN MOLECULAR GENETICS
Year: 2017
Reference: Hum Mol Genet. 2017 Jul 15;26(14):2803-2811. doi: 10.1093/hmg/ddx177.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Farrell, William E; Glossop, John R; Jones, Lindsay Waite; Julia, Antonio; Lopez-Lasanta, Maria; Marsal, Sara; Myers, Richard M; Palau, Nuria; Pluma, Andrea et al.
DOI: 10.1093/hmg/ddx177

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

PMID: 27007234
Journal: JAMA Psychiatry
Year: 2016
Reference: JAMA Psychiatry. 2016 May 1;73(5):497-505. doi: 10.1001/jamapsychiatry.2016.0129.
Impact factor:
Publication type: Paper in international publication
Authors: Andreassen, Ole A; Bacanu, Silviu-Alin; Bakshi, Andrew; Barban, Nicola; Bramon, Elvira; Bruggeman, Richard; Buxbaum, Joseph D; Cairns, Murray J; Cantor, Rita M; Cloninger, C Robert et al.
DOI: 10.1001/jamapsychiatry.2016.0129

A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis.

PMID: 26983453
Journal: RHEUMATOLOGY
Year: 2016
Reference: Rheumatology (Oxford). 2016 Jun;55(6):1106-11. doi: 10.1093/rheumatology/kew035. Epub 2016 Mar 15.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Alperi-Lopez, Mercedes; Bertranpetit, Jaume; Blanco, Francisco; Bridges, S Louis Jr; Canete, Juan D; Codo, Laia; Corominas, Hector; Erra, Alba et al.
DOI: 10.1093/rheumatology/kew035

Microarray study reveals a TGFbeta-Dependent mechanism of fibrosis in discoid lupus erythematosus.

PMID: 26972571
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2016
Reference: Br J Dermatol. 2016 Aug;175(2):302-13. doi: 10.1111/bjd.14539. Epub 2016 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, J; Ferrer, B; Gimenez-Barcons, M; Ordi-Ros, J; Sole, C et al.
DOI: 10.1111/bjd.14539

Genome-Wide Association Study Identifies IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis.

PMID: 26815016
Journal: Ophthalmic Surgery Lasers & Imaging Retina
Year: 2016
Reference: Arthritis Rheumatol. 2016 Jun;68(6):1384-91. doi: 10.1002/art.39591.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Alperi-Lopez, Mercedes; Bertranpetit, Jaume; Blanco, Francisco; Canete, Juan D; Codo, Laia; Corominas, Hector; Erra, Alba; Fernandez-Gutierrez, Benjamin et al.
DOI: 10.1002/art.39591

A deletion at ADAMTS9-MAGI1 locus is associated with psoriatic arthritis risk.

PMID: 25990289
Journal: ANN RHEUM DIS
Year: 2015
Reference: Ann Rheum Dis. 2015 Oct;74(10):1875-81. doi: 10.1136/annrheumdis-2014-207190. Epub 2015 May 19.
Impact factor:
Publication type: Paper in international publication
Authors: Absher, Devin; Alonso, Arnald; Blanco, Ricardo; Canete, Juan D; Castaneda, Santos; Codo, Laia; Corominas, Hector; Dauden, Esteban; Day, Kenneth; de la Cueva, Pablo et al.
DOI: 10.1136/annrheumdis-2014-207190

Childhood trauma in Chronic Fatigue Syndrome: focus on personality disorders and psychopathology.

PMID: 26343462
Journal: COMPR PSYCHIAT
Year: 2015
Reference: Compr Psychiatry. 2015 Oct;62:13-9. doi: 10.1016/j.comppsych.2015.06.010. Epub 2015 Jun 17.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Calvo, Natalia; Casas, Miguel; Castro-Marrero, Jesus; Hernandez-Vara, Jorge; Ramirez, Nicolas; Saez-Francas, Naia et al.
DOI: 10.1016/j.comppsych.2015.06.010

Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis.

PMID: 26336855
Journal: ARTHRITIS RES THER
Year: 2015
Reference: Arthritis Res Ther. 2015 Sep 4;17:242. doi: 10.1186/s13075-015-0737-8.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Alonso, Arnald; Alperi-Lopez, Mercedes; Avila, Gabriela; Blanco, Francisco J; Canete, Juan D; Corominas, Hector; Erra, Alba; Fernandez-Gutierrez, Benjamin; Gonzalez-Alvaro, Isidoro et al.
DOI: 10.1186/s13075-015-0737-8

More on remission of recalcitrant dermatomyositis treated with ruxolitinib.

PMID: 25806935
Journal: NEW ENGL J MED
Year: 2015
Reference: N Engl J Med. 2015 Mar 26;372(13):1273-4. doi: 10.1056/NEJMc1500688#SA1.
Impact factor:
Publication type: Letter whit IF
Authors: Labrador-Horrillo, Moises; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1056/NEJMc1500688#SA1

Neuropsychological impairment in female patients with chronic fatigue syndrome: a preliminary study.

PMID: 24826505
Journal: APPLIED NEUROPSYCHOLOGY
Year: 2014
Reference: Appl Neuropsychol Adult. 2014;21(2):120-7. doi: 10.1080/09084282.2013.771264. Epub 2013 Aug 13.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Eiroa-Orosa, Francisco Jose; Qureshi, Adil; Rodriguez-Urrutia, Amanda; Santamarina-Perez, Pilar et al.
DOI: 10.1080/09084282.2013.771264

Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis.

PMID: 24741583
Journal: Journal of immunology research
Year: 2014
Reference: J Immunol Res. 2014;2014:290797. doi: 10.1155/2014/290797. Epub 2014 Feb 4.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Juarez, Candido; Labrador-Horrillo, Moises; Martinez, Maria Angeles; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI: 10.1155/2014/290797

Clinical and serological findings associated with the expression of ITGAL, PRF1, and CD70 in systemic lupus erythematosus.

PMID: 24238281
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2014
Reference: Clin Exp Rheumatol. 2014 Jan-Feb;32(1):113-6. Epub 2013 Nov 15.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Castro-Marrero, Jesus; Felip, Lledo; Ordi-Ros, Josep; Vilardell-Tarres, Miquel et al.
DOI:

Identification of a novel myositis-associated antibody directed against cortactin.

PMID: 25182205
Journal: AUTOIMMUNITY REVIEWS
Year: 2014
Reference: Autoimmun Rev. 2014 Oct;13(10):1008-12. doi: 10.1016/j.autrev.2014.08.038. Epub 2014 Aug 27.
Impact factor:
Publication type: Paper in international publication
Authors: Grau-Junyent, Josep M; Juarez, Candido; Labrador-Horrillo, Moises; Martinez, Maria Angeles; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI: 10.1016/j.autrev.2014.08.038

Available evidence and outcome of off-label use of rituximab in clinical practice.

PMID: 23700188
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2013
Reference: Eur J Clin Pharmacol. 2013 Sep;69(9):1689-99. doi: 10.1007/s00228-013-1518-4. Epub 2013 May 23.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, A; Alerany, C; Bosch, J A; Cortes-Hernandez, J; Danes, I; Ferrer, A; Lopez, A; Martinez, J; Vallano, A et al.
DOI: 10.1007/s00228-013-1518-4

An unusual case of organizing pneumonia and infection by P. jirovecii.

PMID: 23044282
Journal: Medicina Intensiva
Year: 2013
Reference: Med Intensiva. 2013 May;37(4):299-300. doi: 10.1016/j.medin.2012.08.005. Epub 2012 Oct 6.
Impact factor:
Publication type: Letter whit IF
Authors: Bravo, C; Caralt-Ramisa, B; Farre, M; Fernandez-Codina, A; Masclans, J R; Rello, J et al.
DOI: 10.1016/j.medin.2012.08.005

Idiopathic retroperitoneal fibrosis: a clinicopathological study in 24 Spanish cases.

PMID: 23515600
Journal: CLINICAL RHEUMATOLOGY
Year: 2013
Reference: Clin Rheumatol. 2013 Jun;32(6):889-93. doi: 10.1007/s10067-013-2225-3. Epub 2013 Mar 21.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus; Detorres, Ines; Fernandez-Codina, Andreu; Martinez-Valle, Fernando; Ordi-Ros, Jose; Vilardell-Tarres, Miquel et al.
DOI: 10.1007/s10067-013-2225-3

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome.

PMID: 23514202
Journal: Journal of Translational Medicine
Year: 2013
Reference: J Transl Med. 2013 Mar 20;11:68. doi: 10.1186/1479-5876-11-68.
Impact factor:
Publication type: Paper in international publication
Authors: Alegre, Jose; Blanco, Julia; Cabrera, Cecilia; Carrillo, Jorge; Castro-Marrero, Jesus; Clotet, Bonaventura; Curriu, Marta; Garcia-Quintana, Ana M; Massanella, Marta; Negredo, Eugenia et al.
DOI: 10.1186/1479-5876-11-68

Beta2-glycoprotein I gene polymorphisms Val247Leu and Trp316Ser in Spanish patients with primary antiphospholipid syndrome.

PMID: 21240499
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2012
Reference: Rheumatol Int. 2012 Apr;32(4):927-32. Epub 2011 Jan 15.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1007/s00296-010-1726-5

Change in the discontinuation pattern of tumour necrosis factor antagonists in rheumatoid arthritis over 10 years: data from the Spanish registry BIOBADASER 2.0.

PMID: 21998116
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2012
Reference: Ann Rheum Dis. 2012 Mar;71(3):382-5. Epub 2011 Oct 13.
Impact factor:
Publication type: Paper in international publication
Authors: Anton, Fred; Barcelo, Mireia; Beltran, Chesus; Borras, Juan Jose Garcia; Campos, Cristina; Campos-Fernandez, Cristina; Canete, Juan D; Cano, Laura; Carmona, Loreto; Descalzo, Miguel Angel et al.
DOI: 10.1136/annrheumdis-2011-200302

The Stone Man (Myositis ossificans progressiva).

PMID: 22459412
Journal: JOINT BONE SPINE
Year: 2012
Reference: Joint Bone Spine. 2012 Jul;79(4):415. doi: 10.1016/j.jbspin.2012.02.009. Epub 2012 Mar 27.
Impact factor:
Publication type: Editorail in international publication
Authors: ; et al.
DOI: 10.1016/j.jbspin.2012.02.009

Thalidomide in the treatment of refractory cutaneous lupus: prognostic factors of clinical outcome.

PMID: 21999437
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2012
Reference: Br J Dermatol. 2012 Mar;166(3):616-23. doi: 10.1111/j.1365-2133.2011.10693.x. Epub 2012 Jan 19.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1111/j.1365-2133.2011.10693.x

Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in Patients with Systemic Lupus Erythematosus.

PMID: 21509625
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2011
Reference: J Clin Immunol. 2011 Aug;31(4):584-7. Epub 2011 Apr 21.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1007/s10875-011-9535-5

Systemic lupus erythematosus as a first presentation of common variable immunodeficiency associated with infrequent mannose-binding lectin gene polymorphisms.

PMID: 19851769
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2011
Reference: Rheumatol Int. 2011 Apr;31(4):537-41. Epub 2009 Oct 23.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; et al.
DOI: 10.1007/s00296-009-1209-8

[The role of depression in cognitive inpairment in patients with chronic fatigue syndrome.]

PMID: 21145567
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Mar 12;136(6):239-243. Epub 2010 Dec 9.
Impact factor:
Publication type: Paper in national publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.medcli.2010.07.022

AStream: An R package for annotating LC/MS metabolomic data.

PMID: 21414990
Journal: BIOINFORMATICS
Year: 2011
Reference: Bioinformatics. 2011 May 1;27(9):1339-40. Epub 2011 Mar 16.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1093/bioinformatics/btr138

Nitric Oxide Metabolite Production During Exercise in Chronic Fatigue Syndrome: A Case-Control Study.

PMID: 20469961
Journal: JOURNAL OF WOMENS HEALTH
Year: 2010
Reference: J Womens Health (Larchmt). 2010 Jun;19(6):1073-7.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1089/jwh.2008.1255

Rheumatoid arthritis pharmacogenomics.

PMID: 20415547
Journal: PHARMACOGENOMICS
Year: 2010
Reference: Pharmacogenomics. 2010 May;11(5):617-9.
Impact factor:
Publication type: Paper in international publication
Authors: Julia, Antonio; Marsal, Sara et al.
DOI: 10.2217/pgs.10.53

Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis.

PMID: 19556211
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2010
Reference: Ann Rheum Dis. 2010 Jun;69(6):1239-42. Epub 2009 Jun 24.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1136/ard.2008.106195

Three-dimensional volumetric ultrasonography. Does it improve reliabililty of musculoskeletal ultrasound?

PMID: 20346243
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2010
Reference: Clin Exp Rheumatol. 2010 Jan-Feb;28(1):79-82.
Impact factor:
Publication type: Paper in international publication
Authors: Acebes, Carlos; Batlle-Gualda, Enrique; Brito, Elia; de Agustin, Juan Jose; de Miguel, Eugenio; Garrido, Jesus; Martinez, Agustin; Mayordomo, Lucia; Moller, Ingrid; Moragues, Carmen et al.
DOI:

Serum levels of soluble CD40 ligand at flare and at remission in patients with systemic lupus erythematosus.

PMID: 19332622
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2009
Reference: J Rheumatol. 2009 May;36(5):953-60.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, Eva; Cortes, Fina; Ordi-Ros, Josep; Perez, Eduardo Hermosilla; Urquizu-Padilla, Maria; Vilardell-Tarres, Miquel et al.
DOI: 10.3899/jrheum.080978

DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features.

PMID: 19318394
Journal: LUPUS
Year: 2009
Reference: Lupus. 2009 Apr;18(5):418-23.
Impact factor:
Publication type: Paper in international publication
Authors: Balada, E; Bujan-Rivas, S; Martinez-Valle, F; Ordi-Ros, J; Sellas-Fernandez, A; Vilardell-Tarres, M et al.
DOI: 10.1177/0961203308098189

Obstructive sleep apnea in patients with inflammatory myopathies.

PMID: 19145652
Journal: MUSCLE & NERVE
Year: 2009
Reference: Muscle Nerve. 2009 Feb;39(2):144-9.
Impact factor:
Publication type: Paper in international publication
Authors: Lloberes, Patricia; Romero, Odile; Sampol, Gabriel; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto; Vilardell-Tarres, Miquel et al.
DOI: 10.1002/mus.21204

Association of HLA Class II Genes with Systemic Sclerosis in Spanish Patients.

PMID: 19884273
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2009
Reference: J Rheumatol. 2009 Dec;36(12):2733-6.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.3899/jrheum.090377

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News

Funded by the European Union, this project coordinated by the Vall d'Hebron Research Institute (VHIR) seeks to develop more effective therapies by creating new combinations of existing drugs

The head of the Rheumatology Service at Vall d'Hebron University Hospital and of the Rheumatology research group at VHIR is a highly accomplished rheumatologist with a distinguished career in the field.

It is the first international multi-centre clinical trial to analyse the safety and effect of this treatment for an autoimmune disease.