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Shock, Organ Dysfunction and Resuscitation

The goal of the Shock, Organic Dysfunction and Resuscitation Research Group (SODIR) is comprehensive, innovative research into the areas of shock, acute respiratory failure, acute kidney failure, organic dysfunction, resuscitation and critical patient monitoring. In addition, the research group has a special interest in applying artificial intelligence as an instrument to find innovative solutions for critical patients.

Team

Anna Casas Cubells

Anna Casas Cubells

Administration and Management
Shock, Organ Dysfunction and Resuscitation
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Anna Sánchez Corral

Anna Sánchez Corral

Predoctoral researcher
Shock, Organ Dysfunction and Resuscitation
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Antonio Alvarez Gonzalez

Antonio Alvarez Gonzalez

Shock, Organ Dysfunction and Resuscitation
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Arsenio De la Vega Sanchez

Arsenio De la Vega Sanchez

Predoctoral researcher
Shock, Organ Dysfunction and Resuscitation
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Candido Diaz Lagares

Candido Diaz Lagares

Postdoctoral researcher
Shock, Organ Dysfunction and Resuscitation
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César Laborda Soriano

César Laborda Soriano

Shock, Organ Dysfunction and Resuscitation
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Anna Casas Cubells

Anna Casas Cubells

Administration and Management
Shock, Organ Dysfunction and Resuscitation
Read more
Anna Sánchez Corral

Anna Sánchez Corral

Predoctoral researcher
Shock, Organ Dysfunction and Resuscitation
Read more
Antonio Alvarez Gonzalez

Antonio Alvarez Gonzalez

Shock, Organ Dysfunction and Resuscitation
Read more
Arsenio De la Vega Sanchez

Arsenio De la Vega Sanchez

Predoctoral researcher
Shock, Organ Dysfunction and Resuscitation
Read more
Candido Diaz Lagares

Candido Diaz Lagares

Postdoctoral researcher
Shock, Organ Dysfunction and Resuscitation
Read more
César Laborda Soriano

César Laborda Soriano

Shock, Organ Dysfunction and Resuscitation
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Publications

Identification of spread after deliberated intraneural injection in five mammalian species: not all animal models and needle types are valid for studying the effect of intraneural injections in humans.

PMID: 37699730
Journal: REGIONAL ANESTHESIA AND PAIN MEDICINE
Year: 2023
Reference: Reg Anesth Pain Med. 2023 Sep 12:rapm-2023-104820. doi: 10.1136/rapm-2023-104820.
Impact factor:
Publication type: Paper in international publication
Authors: Boezaart, Andre P; Esteves-Coelho, Marielle; Laredo, Franciso; Perez-Carrasco, Marcos; Perez-Carrasco, Marcos; Reina, Miguel A; Server, Anna; Server, Anna et al.
DOI: 10.1136/rapm-2023-104820

Serum amyloid A as a potential biomarker for disease activity in chronic spontaneous urticaria.

PMID: 37716523
Journal: The journal of allergy and clinical immunology. In practice
Year: 2023
Reference: J Allergy Clin Immunol Pract. 2023 Sep 14:S2213-2198(23)01012-7. doi: 10.1016/j.jaip.2023.09.004.
Impact factor:
Publication type: Paper in international publication
Authors: Baeza, Maria Luisa; Carvallo, Alvaro; Donado, Carmen Diaz; Ferrer, Marta; Ferrer, Marta; Guilarte, Mar; Herrera-Lasso, Valeria; Labrador-Horrillo, Moises; Labrador-Horrillo, Moises; Rodriguez-Garijo, Nuria et al.
DOI: 10.1016/j.jaip.2023.09.004

Endotoxin activity trend and multi-organ dysfunction in critically ill patients with septic shock, who received Polymyxin-B hemadsorption: A multicenter, prospective, observational study.

PMID: 37767775
Journal: ARTIFICIAL ORGANS
Year: 2023
Reference: Artif Organs. 2023 Aug;47(8):1361-1370. doi: 10.1111/aor.14534. Epub 2023 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Antonelli, Massimo; Antonelli, Massimo; Cascarano, Laura; Cutuli, Salvatore Lucio; Cutuli, Salvatore Lucio; Danzi, Vinicio; De Rosa, Silvia; De Rosa, Silvia; Ferrer, Ricard; Ferrer, Ricard et al.
DOI: 10.1111/aor.14534

Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.

PMID: 37799110
Journal: EUROPEAN JOURNAL OF IMMUNOLOGY
Year: 2023
Reference: Eur J Immunol. 2023 Oct 6:e2350633. doi: 10.1002/eji.202350633.
Impact factor:
Publication type: Paper in international publication
Authors: Andres-Leon, Eduardo; Arutyunyan, Anna; Ballestar, Esteban; Barmada, Anis; Calero-Nieto, Fernando J; Carrascosa, Jose Manuel; Carrillo, Jorge; Casafont-Sole, Ivette; Ciudad, Laura; de la Calle-Fabregat, Carlos et al.
DOI: 10.1002/eji.202350633

Methodology of a Large Multicenter Observational Study of Patients with COVID-19 in Spanish Intensive Care Units.

PMID: 35491287
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2022
Reference: Arch Bronconeumol. 2022 Apr;58 Suppl 1:22-31. doi: 10.1016/j.arbres.2022.03.010. Epub 2022 Apr 15.
Impact factor:
Publication type: Paper in national publication
Authors: Albaiceta, Guillermo M; Almansa, Raquel; Anon, Jose M; Barbe, Ferran; Barbera, Carme; Barberan, Jose; Barroso, Marta; Bermejo-Martin, Jesus; Boado, Maria Victoria; Bustamante-Munguira, Elena et al.
DOI: 10.1016/j.arbres.2022.03.010

Precision medicine in sepsis and septic shock: From omics to clinical tools.

PMID: 35433311
Journal: World journal of critical care medicine
Year: 2022
Reference: World J Crit Care Med. 2022 Jan 9;11(1):1-21. doi: 10.5492/wjccm.v11.i1.1. eCollection 2022 Jan 9.
Impact factor:
Publication type: Review in international publication
Authors: Chiscano-Camon, Luis; Ferrer, Ricard; Gonzalez-Lopez, Juan J; Hernandez-Gonzalez, Manuel; Larrosa, Nieves; Martinez-Gallo, Monica; Palmada, Clara; Perez-Carrasco, Marcos; Plata-Menchaca, Erika P; Ribas, Vicent et al.
DOI: 10.5492/wjccm.v11.i1.1

Closed-loop oxygen control improves oxygen therapy in acute hypoxemic respiratory failure patients under high flow nasal oxygen: a randomized cross-over study (the HILOOP study).

PMID: 35422002
Journal: CRITICAL CARE
Year: 2022
Reference: Crit Care. 2022 Apr 14;26(1):108. doi: 10.1186/s13054-022-03970-w.
Impact factor:
Publication type: Paper in international publication
Authors: Caritg, Oriol; Ferrer, Ricard; Garcia-de-Acilu, Marina; Pacheco, Andres; Pacheco, Andres; Ramos, Francisco J; Ricard, Jean-Damien; Roca, Oriol; Santafe, Manel; Schultz, Marcus J et al.
DOI: 10.1186/s13054-022-03970-w

Pulmonary Air Embolism in a COVID-19 Patient with ECMO Support.

PMID: 35353653
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2022
Reference: Am J Respir Crit Care Med. 2022 May 15;205(10):1239. doi: 10.1164/rccm.202109-2181IM.
Impact factor:
Publication type: Letter or abstract
Authors: Argudo, Eduard; Bonilla, Camilo; Chiscano-Camon, Luis; Ferrer, Ricard; Gallart, Elisabet; Giron, Pilar; Martinez-Martinez, Maria; Mera, Abrahan; Palmada, Clara; Papiol, Elisabet et al.
DOI: 10.1164/rccm.202109-2181IM

Evolution of poisoned patients admitted to Spanish intensive care units: Comparing two periods.

PMID: 34294562
Journal: Medicina Intensiva
Year: 2021
Reference: Med Intensiva (Engl Ed). 2021 Oct;45(7):e4-e6. doi: 10.1016/j.medine.2021.07.005. Epub 2021 Jul 20.
Impact factor:
Publication type: Letter whit IF
Authors: Alcaraz Penarrocha, R M; Montero Clavero, F J; Moran Chorro, I; Nogue Xarau, S; Palomar Martinez, M; Socias Mir, A et al.
DOI: 10.1016/j.medine.2021.07.005

Prognostic impact of total metabolic tumor volume in large B-cell lymphoma patients receiving CAR T-cell therapy.

PMID: 34236497
Journal: ANNALS OF HEMATOLOGY
Year: 2021
Reference: Ann Hematol. 2021 Sep;100(9):2303-2310. doi: 10.1007/s00277-021-04560-6. Epub 2021 Jul 8.
Impact factor:
Publication type: Paper in international publication
Authors: Abrisqueta, Pau; Barba, Pere; Bobillo, Sabela; Bosch, Francesc; Carpio, Cecilia; Catala, Eva; Diaz-Lagares, Candido; Iacoboni, Gloria; Jimenez, Moraima; Marin-Niebla, Ana et al.
DOI: 10.1007/s00277-021-04560-6

Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS.

PMID: 34232336
Journal: INTENSIVE CARE MEDICINE
Year: 2021
Reference: Intensive Care Med. 2021 Aug;47(8):851-866. doi: 10.1007/s00134-021-06459-2. Epub 2021 Jul 7.
Impact factor:
Publication type: Review in international publication
Authors: Amato, Marcelo; Antonelli, Massimo; Barbas, Carmen Silvia V; Bongiovanni, Filippo; Cutuli, Salvatore Lucio; de Acilu, Marina Garcia; Frat, Jean-Pierre; Grieco, Domenico Luca; Kress, John P; Maggiore, Salvatore Maurizio et al.
DOI: 10.1007/s00134-021-06459-2

Risk factors and outcomes of ventilator-associated pneumonia in COVID-19 patients: a propensity score matched analysis.

PMID: 34229747
Journal: CRITICAL CARE
Year: 2021
Reference: Crit Care. 2021 Jul 6;25(1):235. doi: 10.1186/s13054-021-03654-x.
Impact factor:
Publication type: Letter whit IF
Authors: Ferrer, Ricard; Martinez-Martinez, Maria; Nuvials, Francesc X; Plata-Menchaca, Erika P; Roca, Oriol et al.
DOI: 10.1186/s13054-021-03654-x

Contingency plan for the intensive care services for the COVID-19 pandemic.

PMID: 32336551
Journal: Medicina Intensiva
Year: 2020
Reference: Med Intensiva. 2020 Aug - Sep;44(6):363-370. doi: 10.1016/j.medin.2020.03.006. Epub 2020 Apr 23.
Impact factor:
Publication type: Paper in national publication
Authors: Ballesteros Sanz, M A; Bodi Saera, M A; Carrasco Rodriguez-Rey, L F; Castellanos Ortega, A; Catalan Gonzalez, M; Diaz Santos, E; Escriba Barcena, A; Frade Mera, M J; Igeno Cano, J C; Lopez, C de Haro et al.
DOI: 10.1016/j.medin.2020.03.006

Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection.

PMID: 32307151
Journal: Revista espanola de anestesiologia y reanimacion
Year: 2020
Reference: Rev Esp Anestesiol Reanim. 2020 May;67(5):261-270. doi: 10.1016/j.redar.2020.03.006. Epub 2020 Apr 16.
Impact factor:
Publication type: Paper in international publication
Authors: Carratala Perales, J M; Cinesi Gomez, C; de Andres Nilsson, J M; de Haro Lopez, C; Egea Santaolalla, C; Farrero Munoz, E; Ferrando Ortola, C; Ferrer Monreal, M; Ferrer Roca, R; Garcia Fernandez, J et al.
DOI: 10.1016/j.redar.2020.03.006

Clinical consensus recommendations regarding non-invasive respiratory support in the adult patient with acute respiratory failure secondary to SARS-CoV-2 infection.

PMID: 32312600
Journal: Medicina Intensiva
Year: 2020
Reference: Med Intensiva. 2020 Oct;44(7):429-438. doi: 10.1016/j.medin.2020.03.005. Epub 2020 Mar 30.
Impact factor:
Publication type: Paper in national publication
Authors: Carratala Perales, Jose Manuel; Cinesi Gomez, Cesar; de Andres Nilsson, Jose M; de Haro Lopez, Candelaria; Egea Santaolalla, Carlos; Farrero Munoz, Eva; Ferrando Ortola, Carlos; Ferrer Monreal, Miquel; Ferrer Roca, Ricard; Garcia Fernandez, Javier et al.
DOI: 10.1016/j.medin.2020.03.005

Effects of the extracorporeal membrane oxygenation circuit on plasma levels of ceftolozane.

PMID: 31387460
Journal: PERFUSION-UK
Year: 2020
Reference: Perfusion. 2020 Apr;35(3):267-270. doi: 10.1177/0267659119864813. Epub 2019 Aug 7.
Impact factor:
Publication type: Paper in international publication
Authors: Argudo, Eduard; Ferrer, Ricard; Grau, Santiago; Lopez-Meseguer, Manuel; Los-Arcos, Ibai; Luque, Sonia; Nuvials, Xavier; Riera, Jordi; Sandiumenge, Alberto et al.
DOI: 10.1177/0267659119864813

Hot topics on challenging areas with procalcitonin use in clinical practice, can it help antibiotic stewardship?

PMID: 31369813
Journal: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Year: 2019
Reference: Int J Antimicrob Agents. 2019 Dec;54(6):686-696. doi: 10.1016/j.ijantimicag.2019.07.016. Epub 2019 Jul 29.
Impact factor: 4.615
Publication type: Editorail in international publication
Authors: Saeed, Kordo, Gonzalez Del Castillo, Juan, Backous, Craig, Drevet, Sabine, Ferrer, Ricard, Gavazzi, Gaetan, Gluck, Eric, Jensen, Jens-Ulrik, Kanizsai, Peter, Ruiz-Rodriguez, Juan Carlos et al.
DOI: 10.1016/j.ijantimicag.2019.07.016

Conservative versus Liberal fluid therapy in Septic Shock (CLASSIC) trial - protocol and statistical analysis plan.

PMID: 31276193
Journal: ACTA ANAESTHESIOLOGICA SCANDINAVICA
Year: 2019
Reference: Acta Anaesthesiol Scand. 2019 Oct;63(9):1262-1271. doi: 10.1111/aas.13434. Epub 2019 Jul 24.
Impact factor: 2.228
Publication type: Paper in international publication
Authors: Jakob, Stephan M, Nalos, Marek, Pettila, Ville, van der Horst, Iwan, Ostermann, Marlies, Mouncey, Paul, Rowan, Kathy, Cecconi, Maurizio, Ferrer, Ricard, Malbrain, Manu L N G et al.
DOI: 10.1111/aas.13434

Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.

PMID: 31184740
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2019
Reference: JAMA. 2019 Jun 11;321(22):2175-2182. doi: 10.1001/jama.2019.7234.
Impact factor: 51.273
Publication type: Paper in international publication
Authors: Lopez, Alexandra, de la Torre, Maria-Carmen, Keough, Elena, Arauzo, Vanesa, Hermosa, Cecilia, Sanchez, Carmen, Tizon, Ana, Tenza, Eva, Laborda, Cesar, Cabanes, Sara et al.
DOI: 10.1001/jama.2019.7234

Plasma interleukin-6 concentration for the diagnosis of sepsis in critically ill adults.

PMID: 31038735
Journal: Cochrane Database of Systematic Reviews
Year: 2019
Reference: Cochrane Database Syst Rev. 2019 Apr 30;4:CD011811. doi: 10.1002/14651858.CD011811.pub2.
Impact factor: 7.755
Publication type: Review in international publication
Authors: Molano Franco, Daniel, Arevalo-Rodriguez, Ingrid, Roque I Figuls, Marta, Montero Oleas, Nadia G, Nuvials, Xavier, Zamora, Javier et al.
DOI: 10.1002/14651858.CD011811.pub2

High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial.

PMID: 28466461
Journal: Annals of Intensive Care
Year: 2017
Reference: Ann Intensive Care. 2017 Dec;7(1):47. doi: 10.1186/s13613-017-0270-9. Epub 2017 May 2.
Impact factor: 3.656
Publication type: Paper in international publication
Authors: Hernandez, Gonzalo, Panadero, Luna, Fernandez, Rafael, Subira, Carles, Frutos-Vivar, Fernando, Rialp, Gemma, Laborda, Cesar, Masclans, Joan Ramon, Lesmes, Amanda et al.
DOI: 10.1186/s13613-017-0270-9

Prone positioning as a bridge to recovery from refractory hypoxaemia following lung transplantationdagger.

PMID: 28449046
Journal: Interactive cardiovascular and thoracic surgery
Year: 2017
Reference: Interact Cardiovasc Thorac Surg. 2017 Aug 1;25(2):292-296. doi: 10.1093/icvts/ivx073.
Impact factor: 0
Publication type: Paper in international publication
Authors: Baldira, Jaume, Lagunes, Leonel, Augustin, Salvador, Roman, Antonio, Due, Maria, Rello, Jordi, Levine, Deborah J, Martinez, Maria, Mazo, Cristopher, Maldonado, Carolina et al.
DOI: 10.1093/icvts/ivx073

The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure.

PMID: 28429310
Journal: Annals of Intensive Care
Year: 2017
Reference: Ann Intensive Care. 2017 Dec;7(1):44. doi: 10.1186/s13613-017-0268-3. Epub 2017 Apr 20.
Impact factor: 3.656
Publication type: Paper in international publication
Authors: Martin-Loeches, Ignacio, Dominguez, Fco Javier Diaz, Moradillo, Susana, Martinez, Braulio Alvarez, Albala, Noelia, Ballesteros, Juan Carlos, Perez, Marta Paz, Losada, Elena Perez, Macias, Santiago, Garcia, Rafael Pajares et al.
DOI: 10.1186/s13613-017-0268-3

Passive leg raising for assessment of volume responsiveness: a review.

PMID: 28323719
Journal: Current Opinion in Critical Care
Year: 2017
Reference: Curr Opin Crit Care. 2017 Jun;23(3):237-243. doi: 10.1097/MCC.0000000000000404.
Impact factor: 3.316
Publication type: Review in international publication
Authors: Mesquida, Jaume, Gruartmoner, Guillem, Ferrer, Ricard et al.
DOI: 10.1097/MCC.0000000000000404

Blog

News

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

Hybrids VITA, developed together with Medical Simulator, reproduces different clinical scenarios for training on how to prevent, diagnose and treat possible complications of ECMO, which is a very complex technique.

Extracorporeal Cardiopulmonary Resuscitation (ECPR) offers therapeutic options for patients in whom conventional cardiopulmonary resuscitation techniques fail to restore the heartbeat.