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Stroke Research

The search for quality and innovation has always been an inherent part of the activity of the Stroke Research Group and represents the common thread that leads us to excellence and continuous improvement.

In recent years, the Stroke Research Group has established itself as a leader in the management, recruitment and international coordination of multicenter clinical trials, as well as in the development of patents for new thrombectomy devices and the creation of new technological solutions and digital platforms to improve the diagnosis, treatment and follow-up of stroke patients. Robust strategic alliances have also been consolidated with public and private entities that ensure the viability and scalability of the research projects initiated in our group.

The Stroke Research Group is made up of a transversal and multidisciplinary team that shares a common idea: to contribute from its area of knowledge to the care and management of stroke through the effective transfer of knowledge and the complementarity of the processes of clinical research.

Team

Rivera Sanchez, Laura

Rivera Sanchez, Laura

Administration and Management
Stroke research
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Alejandro Tomasello Weitz

Alejandro Tomasello Weitz

Stroke research
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Alvaro Garcia Tornel Garcia Camba

Alvaro Garcia Tornel Garcia Camba

Senior researcher
Stroke research
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Carlos Molina Cateriano

Carlos Molina Cateriano

Head of group
Stroke research
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Carlos Piñana Plaza

Carlos Piñana Plaza

Stroke research
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Carole Conforti

Carole Conforti

Research technician
Stroke research
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Rivera Sanchez, Laura

Rivera Sanchez, Laura

Administration and Management
Stroke research
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Alejandro Tomasello Weitz

Alejandro Tomasello Weitz

Stroke research
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Alvaro Garcia Tornel Garcia Camba

Alvaro Garcia Tornel Garcia Camba

Senior researcher
Stroke research
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Carlos Molina Cateriano

Carlos Molina Cateriano

Head of group
Stroke research
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Carlos Piñana Plaza

Carlos Piñana Plaza

Stroke research
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Carole Conforti

Carole Conforti

Research technician
Stroke research
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Research lines

Multimodal, morphological and functional cardiac monitoring in a patients with cryptogenic stroke

Responsible: Dr. Jorge Pagola

IP: -

New procedures and technologies for cerebral reperfusion

Responsible: Dr. Marc Ribo

IP: -

Virtual education platforms for patients with stroke eHealth

Responsible: Dr. Estela Sanjuan

IP: -

Projects

ARTERIAL: una herramienta de inteligencia artificial para la planificación del tratamiento endovascular del ictus.

IP: Marc Ribó Jacobi
Collaborators: Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 60000
Reference: INT22/00109
Duration: 01/01/2023 - 31/12/2024

Optimització del tractament endovascular a l'ictus isquèmic agut

IP: Mª Ángeles Muchada López
Collaborators: Marc Rodrigo Gisbert, Laia Perez Lasarte
Funding agency: Fundació Institut de Recerca HUVH
Funding: 35000
Reference: CARLESM/MARC_RG
Duration: 08/06/2023 - 07/06/2024

TRUSTroke: TRUSTWORTHY PREDICTION OF STROKE OUTCOME ON A FEDERATED LEARNING INFRASTRUCTURE

IP: Carlos Molina Cateriano
Collaborators: Estela Sanjuan Menendez, Laura Rivera Sanchez, Federica Rizzo, Marta Aurora Rubiera Del Fueyo, David Rodriguez Luna
Funding agency: EUROPEAN COMMISSION
Funding: 760000
Reference: TRUSTROKE_HE-HLTH-STAYHLTH2022
Duration: 01/05/2023 - 30/04/2027

(TARTAGLIA) - Fondos Estructura

IP: -
Collaborators: Giorgio Colangelo
Funding agency: Ministerio de Asuntos Económicos y Transf Digital
Funding: 306355.4
Reference: MIA.2021.M02.0005_ESTRUCTURA
Duration: 01/10/2021 - 31/12/2024

Logotip del Ministeri d'Assumptes Econòmics i Transformació Digital

Publications

Accuracy of a Smartwatch to Assess Heart Rate Monitoring and Atrial Fibrillation in Stroke Patients.

PMID: 37430546
Journal: SENSORS
Year: 2023
Reference: Sensors (Basel). 2023 May 10;23(10):4632. doi: 10.3390/s23104632.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Bashir, Saima; Duran, Laura; Francisco, Jaume; Juega, Jesus; Meza, Claudia; Molina, Carlos; Pagola, Jorge; Rodriguez, Maite; Santos, Alba et al.
DOI: 10.3390/s23104632

OSNA Total Tumor Load for the Prediction of Axillary Involvement in Breast Cancer Patients: Should We use Different Thresholds According to the Intrinsic Molecular Subtype? MOTTO Study.

PMID: 37534372
Journal: Clinical pathology (Thousand Oaks, Ventura County,
Year: 2023
Reference: Clin Pathol. 2023 Jul 31;16:2632010X231183693. doi: 10.1177/2632010X231183693. eCollection 2023 Jan-Dec.
Impact factor:
Publication type: Paper in international publication
Authors: Bernet, L; Cordoba, A; Godey, F; Hardisson, D; Peg, V; Prat, A; Rodrigo, M; Ruiz, I; Sanchez-Mendez, J I; Sancho, M et al.
DOI: 10.1177/2632010X231183693

Wall enhancement as a biomarker of intracranial aneurysm instability: a histo-radiological study.

PMID: 37589724
Journal: ACTA NEUROCHIRURGICA
Year: 2023
Reference: Acta Neurochir (Wien). 2023 Aug 17. doi: 10.1007/s00701-023-05739-8.
Impact factor:
Publication type: Paper in international publication
Authors: Arikan, Fuat; Coscojuela, Pilar; De Barros, Andrea; Dinia, Lavinia; Gandara, Dario; Gramegna, Laura Ludovica; Hernandez, David; Luzi, Michele; Martinez-Saez, Elena; Quintana, Manuel et al.
DOI: 10.1007/s00701-023-05739-8

Efficacy and Safety of Oral Factor XIa Inhibitors in Stroke Prevention: A Systematic Review and Meta-Analysis.

PMID: 37685629
Journal: Journal of Clinical Medicine
Year: 2023
Reference: J Clin Med. 2023 Aug 26;12(17):5562. doi: 10.3390/jcm12175562.
Impact factor:
Publication type: Review in international publication
Authors: Alexandrov, Andrei; Caso, Valeria; Eleftheriou, Andreas; Karapanayiotides, Theodore; Katsanos, Aristeidis H; Lemmens, Robin; Mitsias, Panayiotis D; Molina, Carlos A; Molina, Carlos A; Palaiodimou, Lina et al.
DOI: 10.3390/jcm12175562

Added value of patient-reported outcome measures (PROMs) after an acute stroke and early predictors of 90 days PROMs.

PMID: 35695977
Journal: Journal of patient-reported outcomes
Year: 2022
Reference: J Patient Rep Outcomes. 2022 Jun 13;6(1):66. doi: 10.1186/s41687-022-00472-9.
Impact factor: 0
Publication type: Paper in international publication
Authors: Montiel, Estefania, Baladas, Maria, Lallanas, Sofia, Aurin, Eva, Watson, Carolina, Gutierrez, Maria, Cossio, Yolima, Ribo, Marc, Molina, Carlos A, Rubiera, Marta et al.
DOI: 10.1186/s41687-022-00472-9

Increased Number of Passes and Double Stent Retriever Technique Induces Cumulative Injury on Arterial Wall After Mechanical Thrombectomy in a Swine Model.

PMID: 35672562
Journal: Translational Stroke Research
Year: 2022
Reference: Transl Stroke Res. 2022 Jun 8. pii: 10.1007/s12975-022-01044-1. doi: 10.1007/s12975-022-01044-1.
Impact factor: 6.829
Publication type: Paper in international publication
Authors: Tomasello, Alejandro, Ribo, Marc, Gil, Alberto, Li, Jiahui, Esteves, Marielle, Coscojuela, Pilar, de Dios, Marta, Pinana, Carlos, Requena, Manuel, Gragmegna, Laura Ludovica et al.
DOI: 10.1007/s12975-022-01044-1

Thrombectomy vs Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort.

PMID: 35599458
Journal: ANNALS OF NEUROLOGY
Year: 2022
Reference: Ann Neurol. 2022 May 22. doi: 10.1002/ana.26418.
Impact factor: 10.422
Publication type: Paper in international publication
Authors: Sarraj, Amrou, Albers, Gregory W, Blasco, Jordi, Arenillas, Juan F, Ribo, Marc, Hassan, Ameer E, Perez de la Ossa, Natalia, Wu, Teddy Yuan-Hao, Cardona Portela, Pere, Abraham, Michael G et al.
DOI: 10.1002/ana.26418

Effect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.

PMID: 35510397
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Year: 2022
Reference: JAMA. 2022 May 10;327(18):1782-1794. doi: 10.1001/jama.2022.4404.
Impact factor: 56.274
Publication type: Paper in international publication
Authors: Casajuana, Gemma, Jimenez, Xavier, Urra, Xabier, Cardona, Pere, Cocho, Dolores, Purroy, Francisco, Serena, Joaquin, San Roman Manzanera, Luis, Vivanco-Hidalgo, Rosa Maria, Salvat-Plana, Merce et al.
DOI: 10.1001/jama.2022.4404

Bottlenecks in the Acute Stroke Care System during the COVID-19 Pandemic in Catalonia.

PMID: 34023822
Journal: CEREBROVASCULAR DISEASES
Year: 2021
Reference: Cerebrovasc Dis. 2021;50(5):551-559. doi: 10.1159/000516309. Epub 2021 May 21.
Impact factor: 2.762
Publication type: Paper in international publication
Authors: Gomez-Choco, Manuel, Zaragoza-Brunet, Jose, Canovas, David, Krupinski, Jurek, Sala, Natalia Mas, Palomeras, Ernest, Cocho, Dolores, Redondo, Laura, Repullo, Carmen, Sanjurjo, Eduardo et al.
DOI: 10.1159/000516309

Posterior reversible encephalopathy syndrome (PRES) associated with COVID-19.

PMID: 33992168
Journal: JOURNAL OF CLINICAL NEUROSCIENCE
Year: 2021
Reference: J Clin Neurosci. 2021 Jun;88:108-112. doi: 10.1016/j.jocn.2021.03.028. Epub 2021 Mar 23.
Impact factor: 1.961
Publication type: Paper in international publication
Authors: Chen, Austin, Requena, Manuel, Rubiera, Marta, Sanchez, Anna, Siegler, James E, Muchada, Marian, Lallana, Sofia et al.
DOI: 10.1016/j.jocn.2021.03.028

SARS-CoV-2 and Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group.

PMID: 33878892
Journal: STROKE
Year: 2021
Reference: Stroke. 2021 May;52(5):e117-e130. doi: 10.1161/STROKEAHA.120.032927. Epub 2021 Apr 21.
Impact factor: 7.914
Publication type: Paper in international publication
Authors: Goncalves, Bruno, Bock, Daniel, Montaner, Joan, Aghayari Sheikh Neshin, Saeideh, Aguiar de Sousa, Diana, Tenser, Matthew S, Aires, Ana, Alfonso, Mercedes de Lera, Alizada, Orkhan, Azevedo, Elsa et al.
DOI: 10.1161/STROKEAHA.120.032927

Implications of initiating antiseizure drugs prior to the performance of EEG in first epileptic seizures.

PMID: 33875301
Journal: NEUROLOGIA
Year: 2021
Reference: Neurologia (Engl Ed). 2021 Apr 16. pii: S0213-4853(21)00053-0. doi: 10.1016/j.nrl.2021.02.014.
Impact factor: 3.109
Publication type: Paper in national publication
Authors: Llaurado, A, Quintana, M, Fonseca, E, Abraira, L, Toledo, M, Requena, M, Olive, M, Ballve, A, Campos, D, Sueiras, M et al.
DOI: 10.1016/j.nrl.2021.02.014

Computed Tomography Perfusion After Thrombectomy: An Immediate Surrogate Marker of Outcome After Recanalization in Acute Stroke.

PMID: 32404034
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Jun;51(6):1736-1742. doi: 10.1161/STROKEAHA.120.029212. Epub 2020 May 14.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Rubiera, Marta, Garcia-Tornel, Alvaro, Olive-Gadea, Marta, Campos, Daniel, Requena, Manuel, Vert, Carla, Pagola, Jorge, Rodriguez-Luna, David, Muchada, Marian, Boned, Sandra et al.
DOI: 10.1161/STROKEAHA.120.029212

Time Matters: Adjusted Analysis of the Influence of Direct Transfer to Angio-Suite Protocol in Functional Outcome.

PMID: 32390548
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Jun;51(6):1766-1771. doi: 10.1161/STROKEAHA.119.028586. Epub 2020 May 11.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Rubiera, Marta, Molina, Carlos A, Tomasello, Alejandro, Ribo, Marc, Hernandez, David, Rodriguez-Luna, David, Pagola, Jorge, Coscojuela, Pilar, Requena, Manuel, Olive, Marta et al.
DOI: 10.1161/STROKEAHA.119.028586

Large Vessel Occlusion is Independently Associated with Atrial Fibrillation Detection.

PMID: 32347993
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2020
Reference: Eur J Neurol. 2020 Aug;27(8):1618-1624. doi: 10.1111/ene.14281. Epub 2020 May 27.
Impact factor: 4.516
Publication type: Paper in international publication
Authors: Penalba, Anna, Pala, Elena, Rodriguez, Maite, De Lera Alfonso, Mercedes, Arenillas, Juan F, Cabezas, Juan Antonio, Moniche, Francisco, de Torres, Reyes, Montaner, Joan, Gonzalez-Alujas, Teresa et al.
DOI: 10.1111/ene.14281

Sudden Recanalization: A Game-Changing Factor in Endovascular Treatment of Large Vessel Occlusion Strokes.

PMID: 32078495
Journal: STROKE
Year: 2020
Reference: Stroke. 2020 Apr;51(4):1313-1316. doi: 10.1161/STROKEAHA.119.028787. Epub 2020 Feb 14.
Impact factor: 7.19
Publication type: Paper in international publication
Authors: Garcia-Tornel, Alvaro, Rubiera, Marta, Requena, Manuel, Muchada, Marian, Pagola, Jorge, Rodriguez-Luna, David, Deck, Matias, Juega, Jesus, Rodriguez-Villatoro, Noelia, Boned, Sandra et al.
DOI: 10.1161/STROKEAHA.119.028787

Etiology, seizure type, and prognosis of epileptic seizures in the emergency department.

PMID: 30763767
Journal: EPILEPSY & BEHAVIOR
Year: 2019
Reference: Epilepsy Behav. 2019 Mar;92:327-331. doi: 10.1016/j.yebeh.2018.12.008. Epub 2019 Feb 11.
Impact factor: 2.378
Publication type: Paper in international publication
Authors: Olive-Gadea, Marta, Requena, Manuel, Fonseca Hernandez, Elena, Quintana, Manuel, Santamarina, Estevo, Abraira Del Fresno, Laura, Alvarez-Sabin, Jose, Salas-Puig, Xavier, Toledo, Manuel et al.
DOI: 10.1016/j.yebeh.2018.12.008

Blog

News

UMBRELLA, a consortium of over 20 public and private partners, kicks off this week with the aim of revolutionising the entire stroke care pathway in Europe by adopting a holistic approach that covers stroke diagnosis, prevention and care.

The Consortium will create a platform to facilitate a personalised management for stroke patients, enabling a more efficient personalized monitoring and patient follow up.

Funding is key to bringing the neuroprotective drug ApTOLL to market and providing a new therapeutic option for the patients.