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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Publications

Performance of the 2019 ACR/EULAR classification criteria for IgG4-related disease and clinical phenotypes in a Spanish multicentre registry (REERIGG4).

PMID: 32658963
Journal: RHEUMATOLOGY
Year: 2021
Reference: Rheumatology (Oxford). 2021 Jan 5;60(1):217-223. doi: 10.1093/rheumatology/keaa247.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Pinilla, Blanca, Fernandez-Codina, Andreu, Feijoo-Masso, Carlos, Toledano-Macias, Maria, de Miguel-Campo, Borja, Fonseca-Aizpuru, Eva, Saez-Comet, Luis, Lopez-Dupla, Miguel, Hernandez-Rodriguez, Jose, Martinez-Valle, Fernando et al.
DOI: 10.1093/rheumatology/keaa247

Blog

News

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.