About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
We are dedicated to investigate transfusional activity, the alteration of erythrocytes during the conservation period and extracorporeal photoapheresis. We work on the molecular and serological characterization of blood group variants. In non-invasive fetal genotyping strategies due to blood group incompatibilities. We develop iPSC lines and produce in vitro erythrocytes with rare phenotypes. We deepen in the knowledge of epidemiology and the detection of infectious agents relevant for safety of the products supplied by the Blood and Tissue Bank.
We investigate in clinical immunology and develop our own HLA and KIR typing protocols. We develop and incorporate new therapeutic applications in cell therapy including hematopoietic transplantation, cellular immunology and regenerative medicine. We investigate the molecular mechanisms and genotype-phenotype correlation of coagulopathies, haemorrhagic diathesis and other associated congenital pathologies. We develop tools based on the new technologies of parallel massive sequencing with application to the molecular study, genetic counselling and prenatal diagnosis.
PMID: 37767741 Journal: TRANSFUSION Year: 2023 Reference: Transfusion. 2023 Sep 28. doi: 10.1111/trf.17518. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Carrio, Jaume; Coco, Sonia Bakkour; Linnen, Jeffrey M; Ong, Edgar; Piron, Maria; Sauleda, Silvia et al. DOI: 10.1111/trf.17518
PMID: 37810253 Journal: iScience Year: 2023 Reference: iScience. 2023 Sep 19;26(10):107948. doi: 10.1016/j.isci.2023.107948. eCollection 2023 Oct 20. Impact factor: Publication type: Paper in international publication Authors: Almirante, Benito; Buzon, Maria Jose; Chafino, Silvia; Fernandez-Veledo, Sonia; Foguet-Romero, Elisabet; Garcia-Pardo, Graciano; Gomez-Bertomeu, Frederic; Lopez-Dupla, Miguel; Olona, Montserrat; Peraire, Joaquim et al. DOI: 10.1016/j.isci.2023.107948
PMID: 37920152 Journal: Frontiers in Oncology Year: 2023 Reference: Front Oncol. 2023 Oct 18;13:1213898. doi: 10.3389/fonc.2023.1213898. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Baik, Christina S; Bes, Marta; Boral, Andy L; Bowles, Daniel W; Busskamp, Holger; Chan, Henry Lik-Yuen; Curigliano, Giuseppe; Esteban, Juan Ignacio; Gainor, Justin F; Garralda, Elena et al. DOI: 10.3389/fonc.2023.1213898
PMID: 37930713 Journal: EUROPEAN HEART JOURNAL Year: 2023 Reference: Eur Heart J. 2023 Oct 31:ehad529. doi: 10.1093/eurheartj/ehad529. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Busskamp, Holger; Chan, Henry Lik-Yuen; Esteban, Juan Ignacio; Fernandez-Hidalgo, Nuria; Ferreira-Gonzalez, Ignacio; Kohansal-Nodehi, Mahdokht; Kohler, Bruno; Kroeniger, Konstantin; Piratvisuth, Teerha et al. DOI: 10.1093/eurheartj/ehad529
PMID: 35175189 Journal: Blood Transfusion Year: 2022 Reference: Blood Transfus. 2022 Sep;20(5):353-361. doi: 10.2450/2022.0232-21. Epub 2022 Feb 4. Impact factor: Publication type: Paper in international publication Authors: Basile, Luca; Bes, Marta; Ciruela, Pilar; Jane, Mireia; Martinez, Ana; Piron, Maria; Puig, Lluis; Sauleda, Silvia et al. DOI: 10.2450/2022.0232-21
PMID: 35088770 Journal: BLOOD COAGULATION & FIBRINOLYSIS Year: 2022 Reference: Blood Coagul Fibrinolysis. 2022 Jan 1;33(Suppl 1):S19-S21. doi: 10.1097/MBC.0000000000001107. Impact factor: Publication type: Letter or abstract Authors: Corrales, Irene et al. DOI: 10.1097/MBC.0000000000001107
PMID: 34783692 Journal: BLOOD COAGULATION & FIBRINOLYSIS Year: 2022 Reference: Blood Coagul Fibrinolysis. 2022 Jan 1;33(Suppl 1):S12-S14. doi: 10.1097/MBC.0000000000001093. Impact factor: Publication type: Letter or abstract Authors: Batlle, Javier; Borras, Nina; Corrales, Irene; Lopez-Fernandez, Maria Fernanda; Perez-Rodriguez, Almudena; Pinto, Joana Costa; Vidal, Francisco et al. DOI: 10.1097/MBC.0000000000001093
PMID: 34921518 Journal: HLA Year: 2022 Reference: HLA. 2022 Feb;99(2):93-104. doi: 10.1111/tan.14515. Epub 2022 Jan 18. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Larran, Alberto; Caro, Jose L; Closa, Laia; Colomer, Dolors; Estrada, Natalia; Herrero, Maria J; Vidal, Francisco; Xicoy, Blanca; Zamora, Lurdes et al. DOI: 10.1111/tan.14515
PMID: 32705544 Journal: Methods in molecular biology (Clifton, N.J.) Year: 2021 Reference: Methods Mol Biol. 2021;2286:251-261. doi: 10.1007/7651_2020_280. Impact factor: Publication type: Paper in international publication Authors: Cabrera-Perez, Raquel; Coca, Maria Isabel; Martorell, Lluis; Reales, Laura; Rodriguez, Luciano; Vives, Joaquim et al. DOI: 10.1007/7651_2020_280
PMID: 33780553 Journal: JOURNAL OF CLINICAL APHERESIS Year: 2021 Reference: J Clin Apher. 2021 Aug;36(4):563-573. doi: 10.1002/jca.21894. Epub 2021 Mar 29. Impact factor: Publication type: Paper in international publication Authors: Alonso, Nieves; Antelo, Maria Luisa; Cid, Joan; de la Rubia, Javier; Del Rio-Garma, Julio; Fernandez-Docampo, Marta; Fernandez-Sojo, Jesus; Garcia-Candel, Faustino; Garcia-Gala, Jose Maria; Gomez-Segui, Ines et al. DOI: 10.1002/jca.21894
PMID: 33738725 Journal: ADVANCES IN THERAPY Year: 2021 Reference: Adv Ther. 2021 May;38(5):2054-2076. doi: 10.1007/s12325-021-01676-z. Epub 2021 Mar 18. Impact factor: Publication type: Review in international publication Authors: Abril-Gil, Mar; Albert-Bayo, Merce; Alonso-Cotoner, Carmen; Exposito, Elba; Gonzalez-Castro, Ana M; Lobo, Beatriz; Mall, John-P Ganda; Santos, Javier et al. DOI: 10.1007/s12325-021-01676-z
PMID: 33621399 Journal: STEM CELLS Year: 2021 Reference: Stem Cells. 2021 Jul;39(7):866-881. doi: 10.1002/stem.3358. Epub 2021 Mar 3. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Palomo, Ana Belen; Barrot, Carme; Blasco, Maria A; Delgado-Morales, Raul; Edel, Michael J; Esteller, Manel; Garcia-Martinez, Iris; Grau-Bove, Carme; Mezquita-Pla, Jovita; Moran, Sebastian et al. DOI: 10.1002/stem.3358
PMID: 32671674 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2020 Reference: J Clin Immunol. 2020 Oct;40(7):987-1000. doi: 10.1007/s10875-020-00794-7. Epub 2020 Jul 15. Impact factor: Publication type: Paper in international publication Authors: Alsina, Laia; Anton, Maria Carmen; Arostegui, Juan I; Basagana, Maria; Bull, Daniel; Bunney, Tom D; Casals, Ferran; Colobran, Roger; Deya, Angela; Esteve-Sole, Ana et al. DOI: 10.1007/s10875-020-00794-7
PMID: 32562174 Journal: MOLECULAR BIOLOGY REPORTS Year: 2020 Reference: Mol Biol Rep. 2020 Jul;47(7):5145-5154. doi: 10.1007/s11033-020-05588-z. Epub 2020 Jun 19. Impact factor: Publication type: Paper in international publication Authors: Garcia-Lopez, Joan; Grau-Vorster, Marta; Oliver-Vila, Irene; Vivas, Daniel; Vives, Joaquim et al. DOI: 10.1007/s11033-020-05588-z
PMID: 32536916 Journal: Frontiers in Immunology Year: 2020 Reference: Front Immunol. 2020 May 27;11:942. doi: 10.3389/fimmu.2020.00942. eCollection 2020. Impact factor: Publication type: Paper in international publication Authors: Casaroli-Marano, Ricardo P; Cox, Steven; Hernandez, Diana; Madrigal, Alejandro; Querol, Sergio; Rodriguez, Luciano; Samarkanova, Dinara; Samarkanova, Dinara et al. DOI: 10.3389/fimmu.2020.00942
PMID: 32542961 Journal: HAEMOPHILIA Year: 2020 Reference: Haemophilia. 2020 Jul;26(4):637-642. doi: 10.1111/hae.14018. Epub 2020 Jun 15. Impact factor: Publication type: Paper in international publication Authors: Altisent, Carmen; Boggio, Lisa; Chan, Anthony; Kenet, Gili; Mancuso, Maria Elisa; Oldenburg, Johannes; Santagostino, Elena; Seifert, Wilfried et al. DOI: 10.1111/hae.14018
PMID: 30503040 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 Mar;70(3):564-566. doi: 10.1016/j.jhep.2018.10.020. Epub 2018 Nov 28. Impact factor: Publication type: Letter or abstract Authors: Buti, Maria; Diaz-Mejia, Nely; Fernandez-Sojo, Jesus; Munoz-Couselo, Eva; Parra-Lopez, Rafael; Riveiro-Barciela, Mar et al. DOI: 10.1016/j.jhep.2018.10.020
PMID: 30744042 Journal: Cells Year: 2019 Reference: Cells. 2019 Feb 8;8(2). pii: cells8020135. doi: 10.3390/cells8020135. Impact factor: Publication type: Review in national publication Authors: Albert-Bayo, Merce; Alonso-Cotoner, Carmen; Gonzalez-Castro, Ana M; Paracuellos, Irene; Rodriguez-Lagunas, Maria J; Rodriguez-Urrutia, Amanda; Santos, Javier; Vicario, Maria et al. DOI: 10.3390/cells8020135
PMID: 30733543 Journal: BONE MARROW TRANSPLANTATION Year: 2019 Reference: Bone Marrow Transplant. 2019 Jul;54(7):1176. doi: 10.1038/s41409-019-0471-y. Impact factor: Publication type: Letter or abstract Authors: Alonso, Laura; Badell, Isabel; Caballero, Dolores; de Heredia, Cristina Diaz; Ferra, Christelle; Fox, Laura; Garcia-Cadenas, Irene; Jimenez, Maria Jose; Lopez-Corral, Lucia; Martino, Rodrigo et al. DOI: 10.1038/s41409-019-0471-y
PMID: 30672659 Journal: ESC Heart Failure Year: 2019 Reference: ESC Heart Fail. 2019 Apr;6(2):388-395. doi: 10.1002/ehf2.12406. Epub 2019 Jan 23. Impact factor: Publication type: Paper in international publication Authors: Bayes-Genis, Antoni; Campos, Eva; Enrich, Emma; Gastelurrutia, Paloma; Lupon, Josep; Querol, Sergi; Roura, Santiago; Rudilla, Francesc; Santiago-Vacas, Evelyn et al. DOI: 10.1002/ehf2.12406
PMID: 29448295 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2018 Reference: Thromb Haemost. 2018 Mar;118(3):451-460. doi: 10.1055/s-0038-1624581. Epub 2018 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Altisent, Carmen; Carcao, Manuel; Castaman, Giancarlo; Fukutake, Katsuyuki; Garly, May-Lill; Inbal, Aida; Kerlin, Bryce A; Kessler, Craig; Lassila, Riitta; Nugent, Diane et al. DOI: 10.1055/s-0038-1624581
PMID: 29410548 Journal: BONE MARROW TRANSPLANTATION Year: 2018 Reference: Bone Marrow Transplant. 2018 Jun;53(6):741-748. doi: 10.1038/s41409-018-0114-8. Epub 2018 Feb 6. Impact factor: Publication type: Paper in international publication Authors: Balas, Antonio; Barea, Luisa; Carreras, Enric; Castro, Ana; Duarte, Rafael F; Enrich, Emma; Garrido, Gregorio; Gomez-Zumaquero, Juan M; Larrea, Luis; Matesanz, Rafael et al. DOI: 10.1038/s41409-018-0114-8
PMID: 29044825 Journal: HAEMOPHILIA Year: 2018 Reference: Haemophilia. 2018 Jan;24(1):85-96. doi: 10.1111/hae.13361. Epub 2017 Oct 17. Impact factor: Publication type: Paper in international publication Authors: Gringeri, A; Hermans, C; Khair, K; Mazzucconi, M G; Oldenburg, J; Parra, R; Santagostino, E; Spotts, G; Steinitz-Trost, K; Tsakiris, D A et al. DOI: 10.1111/hae.13361
PMID: 29322348 Journal: CYTOTECHNOLOGY Year: 2018 Reference: Cytotechnology. 2018 Feb;70(1):31-44. doi: 10.1007/s10616-017-0186-0. Epub 2018 Jan 10. Impact factor: Publication type: Paper in international publication Authors: Caminal, Marta; Grau-Vorster, Marta; Marin-Gallen, Silvia; Oliver-Vila, Irene; Ramirez-Moncayo, Carmen; Vives, Joaquim et al. DOI: 10.1007/s10616-017-0186-0
PMID: 28445521 Journal: PLoS One Year: 2017 Reference: PLoS One. 2017 Apr 26;12(4):e0176301. doi: 10.1371/journal.pone.0176301. eCollection 2017. Impact factor: Publication type: Paper in international publication Authors: Brunel, Helena; Corrales, Irene; Gavidia-Bovadilla, Giovana; Lopez, Sonia; Martin-Fernandez, Laura; Ramirez, Lorena; Soria, Jose Manuel; Souto, Juan Carlos; Vidal, Francisco et al. DOI: 10.1371/journal.pone.0176301
PMID: 28288829 Journal: CLINICAL MICROBIOLOGY AND INFECTION Year: 2017 Reference: Clin Microbiol Infect. 2017 Nov;23(11):860-867. doi: 10.1016/j.cmi.2017.03.003. Epub 2017 Mar 11. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Buti, Maria; Casillas, Rosario; Esteban, Rafael; Homs, Maria; Nieto, Leonardo; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz, Alicia; Sauleda, Silvia et al. DOI: 10.1016/j.cmi.2017.03.003
PMID: 28205285 Journal: HAEMOPHILIA Year: 2017 Reference: Haemophilia. 2017 Mar;23(2):255-263. doi: 10.1111/hae.13167. Epub 2017 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Barbara, A M; Castaman, G; Catarino, C; Fischer, K; Gilman, E; Iorio, A; Kavakli, K; Lambert, T; Lassila, R; Lissitchkov, T et al. DOI: 10.1111/hae.13167
PMID: 26810137 Journal: PHARMACOGENOMICS JOURNAL Year: 2017 Reference: Pharmacogenomics J. 2017 Jan;17(1):98-104. doi: 10.1038/tpj.2015.89. Epub 2016 Jan 26. Impact factor: Publication type: Paper in international publication Authors: Casas, M; Cormand, B; Corominas, M; Corrales, M; Garcia-Martinez, I; Pagerols, M; Ramos-Quiroga, J A; Ribases, M; Richarte, V; Sanchez-Mora, C et al. DOI: 10.1038/tpj.2015.89
PMID: 26944419 Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Year: 2016 Reference: Eur J Clin Pharmacol. 2016 Jun;72(6):755-64. doi: 10.1007/s00228-016-2032-2. Epub 2016 Mar 5. Impact factor: Publication type: Paper in international publication Authors: Agusti, Antonia; Barbe, Jose; Formiga, Francesc; Garcia, Juana; Lopez-Soto, Alfonso; Moyano, Antonio Fernandez; Ramirez-Duque, Nieves; San-Jose, Antonio; Torres, Olga H; Vallano, Antoni et al. DOI: 10.1007/s00228-016-2032-2
PMID: 27023175 Journal: Translational Psychiatry Year: 2016 Reference: Transl Psychiatry. 2016 Mar 29;6:e769. doi: 10.1038/tp.2016.36. Impact factor: Publication type: Paper in international publication Authors: Abdellaoui, A; Bernard, M; Bigdeli, T B; Boks, M P; Boomsma, D I; Branje, S J T; Brown, S A; Bruinenberg, M; Casas, M; Derks, E M et al. DOI: 10.1038/tp.2016.36
PMID: 27021288 Journal: AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS Year: 2016 Reference: Am J Med Genet B Neuropsychiatr Genet. 2016 Jul;171(5):733-47. doi: 10.1002/ajmg.b.32434. Epub 2016 Mar 29. Impact factor: Publication type: Paper in international publication Authors: Aebi, Marcel; Brevik, Erlend J; Cormand, Bru; Franke, Barbara; Garcia-Martinez, Iris; Haavik, Jan; Jacob, Christian; Johansson, Stefan; Kittel-Schneider, Sarah; Lesch, Klaus-Peter et al. DOI: 10.1002/ajmg.b.32434
PMID: 26783191 Journal: KNEE Year: 2016 Reference: Knee. 2016 Aug;23(4):647-54. doi: 10.1016/j.knee.2015.08.013. Epub 2016 Jan 11. Impact factor: Publication type: Paper in international publication Authors: Codinach, Margarita; Coll, Ruth; Garcia-Lopez, Joan; Huguet, Marina; Lopez, Ramon; Munar, Ana; Orozco, Lluis; Soler, Robert; Vives, Joaquim et al. DOI: 10.1016/j.knee.2015.08.013
Over time, wild boars have approached the city of Barcelona and surrounding areas. As carriers of the hepatitis E virus, they are linked to a study identifying them as a potential source of transmission of this disease.
