About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
We are dedicated to investigate transfusional activity, the alteration of erythrocytes during the conservation period and extracorporeal photoapheresis. We work on the molecular and serological characterization of blood group variants. In non-invasive fetal genotyping strategies due to blood group incompatibilities. We develop iPSC lines and produce in vitro erythrocytes with rare phenotypes. We deepen in the knowledge of epidemiology and the detection of infectious agents relevant for safety of the products supplied by the Blood and Tissue Bank.
We investigate in clinical immunology and develop our own HLA and KIR typing protocols. We develop and incorporate new therapeutic applications in cell therapy including hematopoietic transplantation, cellular immunology and regenerative medicine. We investigate the molecular mechanisms and genotype-phenotype correlation of coagulopathies, haemorrhagic diathesis and other associated congenital pathologies. We develop tools based on the new technologies of parallel massive sequencing with application to the molecular study, genetic counselling and prenatal diagnosis.
PMID: 38003562 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Nov 15;24(22):16372. doi: 10.3390/ijms242216372. Impact factor: Publication type: Paper in international publication Authors: Aguinaco, Reyes; Astigarraga, Itziar; Bastida, Jose Maria; Bernardo, Angel; Carrasco, Marina; Castellano-Tejedor, Carmina; Closa, Laia; Corrales, Irene; Ferrero, Ainara; Garcia-Martinez, Iris et al. DOI: 10.3390/ijms242216372
PMID: 38014779 Journal: AMERICAN JOURNAL OF HEMATOLOGY Year: 2023 Reference: Am J Hematol. 2023 Nov 28. doi: 10.1002/ajh.27131. Impact factor: Publication type: Paper in international publication Authors: Aguinaco, Reyes; Astigarraga, Itziar; Bastida, Jose Maria; Bernardo, Angel; Carrasco, Marina; Clark, Joan; Closa, Laia; Cooper, Nichola; Corrales, Irene; Ferrero, Ainara et al. DOI: 10.1002/ajh.27131
PMID: 38102535 Journal: BMC Neurology Year: 2023 Reference: BMC Neurol. 2023 Dec 15;23(1):441. doi: 10.1186/s12883-023-03477-z. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Palomo, B; Aran, B; Castano, J; Ettrup, Anders; Florea, Ioana; Jansson, Gary; Kuebler, B; Luo, Guogang; Pozo-Rosich, Patricia; Querol Giner, S et al. DOI: 10.1186/s12883-023-03477-z
PMID: 38158197 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2023 Reference: Thromb Haemost. 2023 Dec 29. doi: 10.1055/s-0043-1778070. Impact factor: Publication type: Paper in international publication Authors: Alcaraz-Mateos, Eduardo; Bandini, Perla; Berrueco, Ruben; Borras, Nina; Comes, Natalia; Corrales, Irene; Exposito-Afonso, Idaira Jael; Gassiot, Susanna; Hobeich, Carlos; Jiang, Xiaoyin Sara et al. DOI: 10.1055/s-0043-1778070
PMID: 34708896 Journal: HAEMOPHILIA Year: 2022 Reference: Haemophilia. 2022 Jan;28(1):125-137. doi: 10.1111/hae.14438. Epub 2021 Oct 28. Impact factor: Publication type: Paper in international publication Authors: Borras, Nina; Castillo-Gonzalez, Dunia; Chang-Monteagudo, Arturo; Comes, Natalia; Garrote-Santana, Heidys; Macias-Abraham, Consuelo; Martin-Fernandez, Laura; Rivero-Jimenez, Rene Antonio; Ruiz-Moleon, Vera; Vidal, Francisco et al. DOI: 10.1111/hae.14438
PMID: 35764313 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2022 Reference: Thromb Haemost. 2022 Jun 28. doi: 10.1055/s-0042-1749345. Impact factor: 5.723 Publication type: Paper in international publication Authors: Sanchis-Juan, Alba; Corral, Javier; Ouwehand, Willem H; Vicente, Vicente; Raymond, Frances Lucy; Vidal, Francisco; Undas, Anetta; Puurunen, Marja; Morange, Pierre-Emmanuel; Lopez-Fernandez, Maria Fernanda et al. DOI: 10.1055/s-0042-1749345
PMID: 35804055 Journal: BONE MARROW TRANSPLANTATION Year: 2022 Reference: Bone Marrow Transplant. 2022 Jul 8. pii: 10.1038/s41409-022-01750-2. doi: 10.1038/s41409-022-01750-2. Impact factor: 5.483 Publication type: Paper in international publication Authors: Martino, Rodrigo, Fernandez-Sojo, Jesus, Horton, Roger, Cid, Joan, Azqueta, Carmen, Garcia-Buendia, Ana, Valdivia, Elena, Martorell, Lluis, Rubio-Lopez, Nuria, Codinach, Margarita et al. DOI: 10.1038/s41409-022-01750-2
PMID: 35614316 Journal: BONE MARROW TRANSPLANTATION Year: 2022 Reference: Bone Marrow Transplant. 2022 May 25. pii: 10.1038/s41409-022-01722-6. doi: 10.1038/s41409-022-01722-6. Impact factor: 5.483 Publication type: Letter whit IF Authors: Talarn, Carme, Cid, Joan, Azqueta, Carmen, Valdivia, Elena, Martorell, Lluis, Codinach, Margarita, Marsal, Julia, Mussetti, Alberto, Esquirol, Albert, Trabazo, Maria et al. DOI: 10.1038/s41409-022-01722-6
PMID: 33599111 Journal: HLA Year: 2021 Reference: HLA. 2021 May;97(5):420-427. doi: 10.1111/tan.14221. Epub 2021 Mar 1. Impact factor: Publication type: Paper in international publication Authors: Caro, Jose L; Closa, Laia; Herrero, Maria J; Vidal, Francisco et al. DOI: 10.1111/tan.14221
PMID: 33581698 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2021 Reference: Thromb Haemost. 2021 Nov;121(11):1400-1408. doi: 10.1055/s-0040-1722623. Epub 2021 Feb 13. Impact factor: Publication type: Paper in international publication Authors: Abraham, Aby; Altisent, Carmen; Belletrutti, Mark J; Belyanskaya, Larisa; Carcao, Manuel; Carvalho, Manuela; Chambost, Herve; Chan, Anthony K C; Dubey, Leonid; Ducore, Jonathan et al. DOI: 10.1055/s-0040-1722623
PMID: 33196417 Journal: Blood Transfusion Year: 2021 Reference: Blood Transfus. 2021 Jan;19(1):54-63. doi: 10.2450/2020.0256-20. Epub 2020 Nov 12. Impact factor: Publication type: Paper in international publication Authors: Artaza, Gonzalo; Contreras, Enric; Ene, Gabriela; Ferrer, Gonzalo; Garcia, Nadia; Grifols, Joan; Jaramillo, Anny; Llopis, Jaume; Maglio, Laura; Millan, Anna et al. DOI: 10.2450/2020.0256-20
PMID: 34119882 Journal: TISSUE & CELL Year: 2021 Reference: Tissue Cell. 2021 Oct;72:101572. doi: 10.1016/j.tice.2021.101572. Epub 2021 Jun 4. Impact factor: 2.466 Publication type: Paper in international publication Authors: Perez, M L, Castells-Sala, C, Lopez-Chicon, P, Nieto-Nicolau, N, Aiti, A, Farinas, O, Casaroli-Marano, R P, Porta, O, Vilarrodona, A et al. DOI: 10.1016/j.tice.2021.101572
PMID: 32379400 Journal: JOURNAL OF THROMBOSIS AND HAEMOSTASIS Year: 2020 Reference: J Thromb Haemost. 2020 Sep;18(9):2145-2154. doi: 10.1111/jth.14886. Epub 2020 Aug 25. Impact factor: Publication type: Paper in international publication Authors: Badiee, Zahra; Baghaipour, Mohammad-Reza; Baronciani, Luciano; Battle, Javier; Berntorp, Erik; Bodo, Imre; Budde, Ulrich; Castaman, Giancarlo; Charles Richard Morris, Hay; Eikenboom, Jeroen C J et al. DOI: 10.1111/jth.14886
PMID: 32303710 Journal: BONE MARROW TRANSPLANTATION Year: 2020 Reference: Bone Marrow Transplant. 2020 Aug;55(8):1623-1631. doi: 10.1038/s41409-020-0890-9. Epub 2020 Apr 17. Impact factor: Publication type: Paper in international publication Authors: Borras, Nina; Campos, Eva; Corrales, Irene; Enrich, Emma; Martorell, Lluis; Querol, Sergi; Rudilla, Francesc; Sanchez, Mar; Vidal, Francisco et al. DOI: 10.1038/s41409-020-0890-9
PMID: 32304998 Journal: EBioMedicine Year: 2020 Reference: EBioMedicine. 2020 Apr;54:102729. doi: 10.1016/j.ebiom.2020.102729. Epub 2020 Apr 15. Impact factor: Publication type: Paper in international publication Authors: Agusti, Elba; Aylagas, Miriam; Bayes-Genis, Antoni; Camara-Rosell, Maria Luisa; Cediel, German; Coca, Maria Isabel; Coll, Ruth; Farre, Ramon; Galvez-Monton, Carolina; Garcia-Lopez, Joan et al. DOI: 10.1016/j.ebiom.2020.102729
PMID: 32281925 Journal: Blood Transfusion Year: 2020 Reference: Blood Transfus. 2020 May;18(3):208-216. doi: 10.2450/2020.0305-19. Epub 2020 Apr 3. Impact factor: Publication type: Paper in international publication Authors: Azqueta, Carmen; Codinach, Margarita; Coll, Ruth; Escudero, Jose R; Farssac, Elisenda; Gaitan, Jesus; Querol, Sergio; Rodriguez, Luciano; Samarkanova, Dinara; Samarkanova, Dinara et al. DOI: 10.2450/2020.0305-19
PMID: 30444298 Journal: HAEMOPHILIA Year: 2019 Reference: Haemophilia. 2019 Jan;25(1):144-153. doi: 10.1111/hae.13628. Epub 2018 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Alonso, Nieves; Altisent, Carmen; Alvarez-Roman, Maria Teresa; Bermejo, Nuria; Bonanad, Santiago; De la Corte-Rodriguez, Hortensia; Fernandez-Arias, Isabel; Fernandez-Mosteirin, Nuria; Garcia-Candel, Faustino; Garcia-Frade, Luis Javier et al. DOI: 10.1111/hae.13628
PMID: 30447901 Journal: CYTOTHERAPY Year: 2019 Reference: Cytotherapy. 2019 Jan;21(1):32-40. doi: 10.1016/j.jcyt.2018.09.009. Epub 2018 Nov 15. Impact factor: Publication type: Paper in international publication Authors: Blanco, Margarita; Codinach, Margarita; Garcia-Lopez, Joan; Grau-Vorster, Marta; Oliver-Vila, Irene; Rodriguez, Luciano; Torrents-Zapata, Silvia; Vivas, Daniel; Vives, Joaquim et al. DOI: 10.1016/j.jcyt.2018.09.009
PMID: 31425551 Journal: PLoS Pathogens Year: 2019 Reference: PLoS Pathog. 2019 Aug 19;15(8):e1007991. doi: 10.1371/journal.ppat.1007991. eCollection 2019 Aug. Impact factor: 6.463 Publication type: Paper in international publication Authors: Grau-Exposito, Judith, Luque-Ballesteros, Laura, Navarro, Jordi, Curran, Adrian, Burgos, Joaquin, Ribera, Esteban, Torrella, Ariadna, Planas, Bibiana, Badia, Rosa, Martin-Castillo, Mario et al. DOI: 10.1371/journal.ppat.1007991
PMID: 31353832 Journal: HLA Year: 2019 Reference: HLA. 2019 Oct;94(4):347-359. doi: 10.1111/tan.13644. Epub 2019 Aug 6. Impact factor: 2.785 Publication type: Paper in international publication Authors: Enrich, Emma, Campos, Eva, Martorell, Lluis, Herrero, Maria Jose, Vidal, Francisco, Querol, Sergi, Rudilla, Francesc et al. DOI: 10.1111/tan.13644
PMID: 29212942 Journal: JOURNAL OF VIROLOGY Year: 2018 Reference: J Virol. 2018 Feb 12;92(5):e01805-17. doi: 10.1128/JVI.01805-17. Print 2018 Mar 1. Impact factor: Publication type: Paper in international publication Authors: Alcami, Jose; Benito, Jose Miguel; Casado, Concepcion; Coiras, Maite; Dapena, Marta; Del Romero, Jorge; Dominguez-Molina, Beatriz; Garcia, Felipe; Gomez, Josep; Iribarren, Jose Antonio et al. DOI: 10.1128/JVI.01805-17
PMID: 29732577 Journal: TRANSFUSION Year: 2018 Reference: Transfusion. 2018 Jul;58(7):1732-1738. doi: 10.1111/trf.14651. Epub 2018 May 6. Impact factor: Publication type: Paper in international publication Authors: Amat, Lluis; Arroyo, JoseLuis; Azqueta, Carmen; Brull, Jose Maria; Cemborain, Arantxa; Cuadras, Daniel; Gaya, Antoni; Gomez Roig, Maria Dolores; Gomez, Susana; Lin, Xinxin et al. DOI: 10.1111/trf.14651
PMID: 28815880 Journal: HAEMOPHILIA Year: 2018 Reference: Haemophilia. 2018 Mar;24(2):211-220. doi: 10.1111/hae.13320. Epub 2017 Aug 16. Impact factor: 2.768 Publication type: Paper in international publication Authors: Liesner, R J, Knaub, S, Neufeld, E J, Walter, O, Belyanskaya, L, Pavlova, A, Altisent, C, Belletrutti, M J, Borel-Derlon, A, Carcao, M et al. DOI: 10.1111/hae.13320
PMID: 29924855 Journal: PLoS One Year: 2018 Reference: PLoS One. 2018 Jun 20;13(6):e0197876. doi: 10.1371/journal.pone.0197876. eCollection 2018. Impact factor: 2.766 Publication type: Paper in international publication Authors: Perez-Rodriguez, Almudena, Batlle, Javier, Corrales, Irene, Borras, Nina, Rodriguez-Trillo, Angela, Loures, Esther, Cid, Ana Rosa, Bonanad, Santiago, Cabrera, Noelia, Moret, Andres et al. DOI: 10.1371/journal.pone.0197876
PMID: 27811020 Journal: BLOOD Year: 2017 Reference: Blood. 2017 Jan 26;129(4):525-532. doi: 10.1182/blood-2016-06-722249. Epub 2016 Nov 3. Impact factor: Publication type: Paper in international publication Authors: Bergamaschi, Paola; Bittencourt, Henrique; Cunha, Renato; Diaz-de-Heredia, Cristina; Fernandes, Francisco; Gluckman, Eliane; Kogler, Gesine; Lamas, Carmen H; Michel, Gerard; Panepucci, Rodrigo A et al. DOI: 10.1182/blood-2016-06-722249
PMID: 28153425 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2017 Reference: Arch Bronconeumol. 2017 Jul;53(7):407-408. doi: 10.1016/j.arbres.2016.10.002. Epub 2017 Jan 31. Impact factor: Publication type: Review in national publication Authors: Aleman, Carmen; Fernandez de Sevilla, Tomas; Garcia, Jorge; Jauregui, Alberto; Persiva, Oscar; Vazquez, Ana et al. DOI: 10.1016/j.arbres.2016.10.002
PMID: 28158588 Journal: CLINICAL INFECTIOUS DISEASES Year: 2017 Reference: Clin Infect Dis. 2017 May 1;64(9):1191-1197. doi: 10.1093/cid/cix095. Impact factor: Publication type: Paper in international publication Authors: Blanco, Jose Ramon; De Luna-Romero, Marta; De Ory, Santiago J; De Pablo-Bernal, Rebeca S; Ferrando-Martinez, Sara; Genebat, Miguel; Gutierrez, Felix; Koup, Richard A; Leal, Manuel; Montero, Marta et al. DOI: 10.1093/cid/cix095
PMID: 28846465 Journal: JOURNAL OF CLINICAL ONCOLOGY Year: 2017 Reference: J Clin Oncol. 2017 Oct 20;35(30):3425-3432. doi: 10.1200/JCO.2017.72.6869. Epub 2017 Aug 28. Impact factor: 24.008 Publication type: Paper in international publication Authors: Dominietto, Alida, Castagna, Luca, Afanasyev, Boris, Robinson, Stephen, Blaise, Didier, Corradini, Paolo, Itala-Remes, Maija, Bermudez, Arancha, Forcade, Edouard, Russo, Domenico et al. DOI: 10.1200/JCO.2017.72.6869
PMID: 27181368 Journal: Scientific Reports Year: 2016 Reference: Sci Rep. 2016 May 16;6:25944. doi: 10.1038/srep25944. Impact factor: Publication type: Paper in international publication Authors: Aguilo, Silvia; Alonso, Judith; Ferran, Beatriz; Marti-Pamies, Ingrid; Martinez-Gonzalez, Jose; Rodriguez, Cristina; Rodriguez-Calvo, Ricardo; Vidal, Francisco et al. DOI: 10.1038/srep25944
PMID: 26714021 Journal: EUROPEAN JOURNAL OF HAEMATOLOGY Year: 2016 Reference: Eur J Haematol. 2016 May;96(5):461-74. doi: 10.1111/ejh.12730. Epub 2016 Feb 4. Impact factor: 2.544 Publication type: Review in international publication Authors: Mingot-Castellano, Maria Eva, Alvarez-Roman, Maria Teresa, Lopez-Fernandez, Maria Fernanda, Altisent-Roca, Carmen, Canaro-Hirnyk, Mariana Isabel, Jimenez-Yuste, Victor, Cid-Haro, Ana Rosa, Perez-Garrido, Rosario, Sedano-Balbas, Carmen et al. DOI: 10.1111/ejh.12730
PMID: 26755710 Journal: BLOOD Year: 2016 Reference: Blood. 2016 Apr 7;127(14):1761-9. doi: 10.1182/blood-2015-09-669234. Epub 2016 Jan 11. Impact factor: 11.841 Publication type: Paper in international publication Authors: Santagostino, Elena, Martinowitz, Uri, Lissitchkov, Toshko, Pan-Petesch, Brigitte, Hanabusa, Hideji, Oldenburg, Johannes, Boggio, Lisa, Negrier, Claude, Pabinger, Ingrid, von Depka Prondzinski, Mario et al. DOI: 10.1182/blood-2015-09-669234
PMID: 26969334 Journal: CLINICAL THERAPEUTICS Year: 2016 Reference: Clin Ther. 2016 Apr;38(4):936-44. doi: 10.1016/j.clinthera.2016.02.015. Epub 2016 Mar 8. Impact factor: 2.925 Publication type: Paper in international publication Authors: Korth-Bradley, Joan M, Rendo, Pablo, Smith, Lynne, Altisent, Carmen et al. DOI: 10.1016/j.clinthera.2016.02.015
Over time, wild boars have approached the city of Barcelona and surrounding areas. As carriers of the hepatitis E virus, they are linked to a study identifying them as a potential source of transmission of this disease.
