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Transfusional Medicine

We are dedicated to investigate transfusional activity, the alteration of erythrocytes during the conservation period and extracorporeal photoapheresis. We work on the molecular and serological characterization of blood group variants. In non-invasive fetal genotyping strategies due to blood group incompatibilities. We develop iPSC lines and produce in vitro erythrocytes with rare phenotypes.

We deepen in the knowledge of epidemiology and the detection of infectious agents relevant for safety of the products supplied by the Blood and Tissue Bank.

We investigate in clinical immunology and develop our own HLA and KIR typing protocols. We develop and incorporate new therapeutic applications in cell therapy including hematopoietic transplantation, cellular immunology and regenerative medicine.

We investigate the molecular mechanisms and genotype-phenotype correlation of coagulopathies, haemorrhagic diathesis and other associated congenital pathologies. We develop tools based on the new technologies of parallel massive sequencing with application to the molecular study, genetic counselling and prenatal diagnosis.

Team

Natàlia Comes Fernández

Natàlia Comes Fernández

Research technician
Transfusional Medicine
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Nuria Font Cotet

Nuria Font Cotet

Transfusional Medicine
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Nuria Nogués Gálvez

Nuria Nogués Gálvez

Transfusional Medicine
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Rafael Parra López

Rafael Parra López

Head of group
Transfusional Medicine
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Rut Mora Buch

Rut Mora Buch

Postdoctoral researcher
Transfusional Medicine
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Sergi Querol Giner

Sergi Querol Giner

Transfusional Medicine
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Natàlia Comes Fernández

Natàlia Comes Fernández

Research technician
Transfusional Medicine
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Nuria Font Cotet

Nuria Font Cotet

Transfusional Medicine
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Nuria Nogués Gálvez

Nuria Nogués Gálvez

Transfusional Medicine
Read more
Rafael Parra López

Rafael Parra López

Head of group
Transfusional Medicine
Read more
Rut Mora Buch

Rut Mora Buch

Postdoctoral researcher
Transfusional Medicine
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Sergi Querol Giner

Sergi Querol Giner

Transfusional Medicine
Read more

Publications

Extrinsic modulation of integrin alpha6 and progenitor cell behavior in mesenchymal stem cells.

PMID: 32659733
Journal: Stem Cell Research
Year: 2020
Reference: Stem Cell Res. 2020 Jun 30;47:101899. doi: 10.1016/j.scr.2020.101899.
Impact factor: 4.489
Publication type: Paper in international publication
Authors: Farinas, Oscar, Savio, Andres, Vilarrodona, Anna, Casaroli-Marano, Ricardo P, de la Torre, Raquel M, Nieto-Nicolau, Nuria et al.
DOI: 10.1016/j.scr.2020.101899

Neonatal alloimmune thrombocytopenia due to anti-HPA 5a in a HPA-5a homozygous neonate.

PMID: 32763115
Journal: TRANSFUSION AND APHERESIS SCIENCE
Year: 2020
Reference: Transfus Apher Sci. 2020 Dec;59(6):102880. doi: 10.1016/j.transci.2020.102880. Epub 2020 Jul 22.
Impact factor: 1.285
Publication type: Letter or abstract
Authors: Porta, R, Serrano, P, Paltrinieri, A, Ristic, G, Canals, C, Lozano, M et al.
DOI: 10.1016/j.transci.2020.102880

Induced pluripotent stem cell-derived lung alveolar epithelial type II cells reduce damage in bleomycin-induced lung fibrosis.

PMID: 32493487
Journal: Stem Cell Research & Therapy
Year: 2020
Reference: Stem Cell Res Ther. 2020 Jun 3;11(1):213. doi: 10.1186/s13287-020-01726-3.
Impact factor: 5.116
Publication type: Paper in international publication
Authors: Alvarez-Palomo, Belen, Sanchez-Lopez, Luis Ignacio, Moodley, Yuben, Edel, Michael J, Serrano-Mollar, Anna et al.
DOI: 10.1186/s13287-020-01726-3

Common Genetic Variants in ABO and CLEC4M Modulate the Pharmacokinetics of Recombinant FVIII in Severe Hemophilia A Patients.

PMID: 32726853
Journal: THROMBOSIS AND HAEMOSTASIS
Year: 2020
Reference: Thromb Haemost. 2020 Oct;120(10):1395-1406. doi: 10.1055/s-0040-1714214. Epub 2020 Jul 29.
Impact factor: 4.379
Publication type: Paper in international publication
Authors: Vidal, Francisco, Alonso, Sofia, Corrales, Irene, Megias-Vericat, Juan Eduardo, Garcia-Martinez, Iris, Borras, Nina, Martorell, Marta, Parra, Rafael, Altisent, Carme, Ramirez, Lorena et al.
DOI: 10.1055/s-0040-1714214

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Over time, wild boars have approached the city of Barcelona and surrounding areas. As carriers of the hepatitis E virus, they are linked to a study identifying them as a potential source of transmission of this disease.