Skip to main content

Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Publications

Nuclear and cytosolic pS727-STAT3 levels correlate with overall survival of patients affected by clear cell renal cell carcinoma (ccRCC).

PMID: 33772065
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Mar 26;11(1):6957. doi: 10.1038/s41598-021-86218-x.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Arevalo, Jazmine, Lorente, David, Trilla, Enrique, Salcedo, Maria Teresa, Morote, Juan, Meseguer, Anna et al.
DOI: 10.1038/s41598-021-86218-x

Immune analysis of lymph nodes in relation to the presence or absence of tumor infiltrating lymphocytes in triple-negative breast cancer.

PMID: 33743482
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2021
Reference: Eur J Cancer. 2021 May;148:134-145. doi: 10.1016/j.ejca.2021.01.037. Epub 2021 Mar 17.
Impact factor: 9.162
Publication type: Paper in international publication
Authors: Munoz-Couselo, Eva, Perez-Garcia, Jose, Marti, Merce, Blanco-Heredia, Juan, Anjos, Carla Dos, Vazquez, Miguel, De Mattos-Arruda, Leticia, Cortes, Javier, Curigliano, Giuseppe, Schmid, Peter et al.
DOI: 10.1016/j.ejca.2021.01.037

Hepatic sinusoidal obstruction syndrome associated with nivolumab: an uncommon adverse event related to immune checkpoint inhibitors.

PMID: 33723557
Journal: Journal of Gastrointestinal and Liver Diseases
Year: 2021
Reference: J Gastrointestin Liver Dis. 2021 Mar 13;30(1):171-172. doi: 10.15403/jgld-3207.
Impact factor: 2.008
Publication type: Letter whit IF
Authors: Riveiro-Barciela, Mar, Gonzalez-Sans, Didac, Marmolejo, David, Salcedo, Maria-Teresa, Munoz-Couselo, Eva et al.
DOI: 10.15403/jgld-3207

Differential Characteristics and Outcomes of Asian and non-Asian Patients with HBV-related Hepatocellular Carcinoma.

PMID: 33713386
Journal: LIVER INTERNATIONAL
Year: 2021
Reference: Liver Int. 2021 Aug;41(8):1922-1932. doi: 10.1111/liv.14877. Epub 2021 Apr 1.
Impact factor: 5.828
Publication type: Paper in international publication
Authors: Huang, Daniel Q, Hoang, Joseph K, Leong, Jennifer, Riveiro-Barciela, Mar, Yang, Ju Dong, Accarino, Elena Vargas, Thin, Khin, Trinh, Lindsey, Cheung, Ramsey C, Roberts, Lewis R et al.
DOI: 10.1111/liv.14877

Evaluation of the intraoperative human papilloma virus test as a marker of early cure at 12 months after electrosurgical excision procedure in patients with cervical High Grade Squamous Intraepithelial Lesion: a prospective cohort study.

PMID: 31502397
Journal: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
Year: 2020
Reference: BJOG. 2020 Jan;127(1):99-105. doi: 10.1111/1471-0528.15932. Epub 2019 Sep 25.
Impact factor: 4.663
Publication type: Paper in international publication
Authors: Garcia, A, Centeno, C, Gil-Moreno, A, Dinares, C, Hernandez, J, Cabrera, S, Rabasa, J, Bradbury, M, Sanchez-Iglesias, J L, Guerrero, D et al.
DOI: 10.1111/1471-0528.15932

Blog

News

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

Icona fitxers

Current Rates

PDF 0.25 MB

Icona fitxers

Rates Anatomia Patologica VHIR 2021

PDF 0.22 MB