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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Team

Cleofé Romagosa Pérez-Portabell

Cleofé Romagosa Pérez-Portabell

Main researcher
Translational Molecular Pathology
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Javier Hernandez Losa

Javier Hernandez Losa

Main researcher
Translational Molecular Pathology
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Josep Castellví Vives

Josep Castellví Vives

Senior researcher
Translational Molecular Pathology
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Marta Cano Galietero

Marta Cano Galietero

Predoctoral researcher
Translational Molecular Pathology
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Marta Sese Faustino

Marta Sese Faustino

Postdoctoral researcher
Translational Molecular Pathology
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Mercedes Martinez Mansilla

Mercedes Martinez Mansilla

Research technician
Translational Molecular Pathology
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Cleofé Romagosa Pérez-Portabell

Cleofé Romagosa Pérez-Portabell

Main researcher
Translational Molecular Pathology
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Javier Hernandez Losa

Javier Hernandez Losa

Main researcher
Translational Molecular Pathology
Read more
Josep Castellví Vives

Josep Castellví Vives

Senior researcher
Translational Molecular Pathology
Read more
Marta Cano Galietero

Marta Cano Galietero

Predoctoral researcher
Translational Molecular Pathology
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Marta Sese Faustino

Marta Sese Faustino

Postdoctoral researcher
Translational Molecular Pathology
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Mercedes Martinez Mansilla

Mercedes Martinez Mansilla

Research technician
Translational Molecular Pathology
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Projects

Búsqueda de firmas proteómicas y dianas terapéuticas en el cáncer de ovario seroso de alto grado avanzado resistente a platino

IP: Antonio Gil Moreno
Collaborators: Vicente Bebia Conesa, Francesc Xavier Serra Marin, Marta Rebull Santamaria, Martina Angeles Fite, Melissa Bradbury Lobato, Lourdes Elena Salazar Huayna, Búsqueda de firmas proteómicas y dianas terapéuticas en el cáncer de ovario seroso de alto grado avanzado resistente a platino, Melek Denizli , Valeria Tubita
Funding agency: Instituto de Salud Carlos III
Funding: 196250
Reference: PI24/01509
Duration: 01/01/2025 - 31/12/2027

Nanocápsulas que combinan nuevos fármacos con quimioterapia convencional para curar cánceres resistentes

IP: Matilde Lleonart Pajarin
Collaborators: Katerin Ingrid Rojas Laimito, Irene Braña Garcia, Yoelsis Garcia Mayea, David Virós Porcuna, Juan Fernando Fuentes Cabrera, Josep Castellví Vives, Marina Bataller Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 318750
Reference: AC24/00057
Duration: 01/01/2025 - 31/12/2027

Establecimiento de una estrategia combinada en carcinoma escamoso de cabeza y cuello (HNSCC): una herramienta eficaz para superar los tumores quimiorresistentes.

IP: Matilde Lleonart Pajarin
Collaborators: Katerin Ingrid Rojas Laimito, Yoelsis Garcia Mayea, Juan Lorente Guerrero, Juan Fernando Fuentes Cabrera, Sergio Benavente Norza, Josep Castellví Vives, Marina Bataller Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 240000
Reference: PI24/00630
Duration: 01/01/2025 - 31/12/2027

MNK - EB1

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Inés de Torres Ramirez, Adriana Martinez Cifuentes, Sara Garcia Ortega, Elena Muro Blanc, Marta Cano Galietero, Vicente Peg Camara, Stefan Hummer
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 189970
Reference: SLT036/24/000026
Duration: 21/12/2024 - 20/12/2026

Blog

News

The ten groups within the Cancer Area combine basic, translational and clinical research to identify new targets, biomarkers and therapeutic strategies

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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