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Odevixibat (A4250) in children with biliary atresia (BOLD-EXT)

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Ensayo aleatorizado, doble ciego, controlado con placebo y de grupos paralelos para investigar los efectos de dos dosis (ajuste ascendente a un régimen de dosis fijas) de BI 685509 oral en la hipertensión portal después de 24 semanas de tratamiento en pacientes con hipertensión portal clínicamente significativa (HPCS) en cirrosis compensada.

  • Protocol code: 1366-0021
  • EudraCT code: 2021-001285-38
  • Pathology: Factors que influencien en l’estat de salut i contacte amb els serveis de salut
  • Principal investigator:  Ventura Cots, Meritxell
  • Research group:  Malalties hepàtiques
  • Service: Hepatologia
  • Phase: Fase II
  • Recruiting: Open
  • Status: Open

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Estudio de prolongación multicéntrico, de un solo grupo, abierto y de extensión para evaluar la seguridad y la eficacia a largo plazo de ocrelizumab en pacientes con esclerosis múltiple

  • Protocol code: MN43964
  • EudraCT code: 2021-005746-15
  • Pathology: Malalties del sistema nerviós
  • Principal investigator:  Montalban Gairín, Xavier
  • Research group:  Neuroimmunologia clínica
  • Service: Neuroimmunologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de extensión de 52 semanas de fase III, multicéntrico y abierto para evaluar a seguridad y la tolerabilidad a largo plazo de atogepant por vía oral para laprevención de la migraña en participantes con migraña crónica u ocasional

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Estudio de fase II, aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia, la seguridad, la tolerabilidad, la farmacocinética y la farmacodinámica de TAK-341 intravenoso en sujetos con atrofia multisistémica

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Estudio fundamental, de fase 3, multicéntrico para evaluar la seguridad y la eficacia de la terapia fotodinámica focalizada vascular con TOOKAD (padeliporfina) en el tratamiento del cáncer urotelial de vías urinarias altas de grado bajo

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Ensayo de extensión abierto para evaluar la seguridad a largo plazo de KVD900, un inhibidor oral de la calicreína plasmática, para el tratamiento ademanda de las crisis de angioedema en pacientes adolescentes y adultos con angioedema hereditario de tipo I o II

  • Protocol code: KVD900-302
  • EudraCT code: 2021-001176-42
  • Pathology: Malalties del sistema respiratori
  • Principal investigator:  Guilarte Clavero, Mar
  • Research group:  Malalties sistèmiques
  • Service: Medicina Interna
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de fase II, aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y la seguridad de la pimavanserina para el tratamiento de la irritabilidad asociada al trastorno del espectro autista.

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IMPAHCT: Estudio de fase IIb/III, aleatorizado, doble ciego, controlado con placebo, de búsqueda de dosis de 24 semanas y confirmatorio para evaluar la seguridad y eficacia de AV-101 en pacientes con hipertensión arterial pulmonar (HAP)

  • Protocol code: AV-101-002
  • EudraCT code: 2021-001910-13
  • Pathology: Diseases of the respiratory system
  • Principal investigator:  López Meseguer, Manuel
  • Research group:  Pneumologia
  • Service: Pneumologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Tancat

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Estudio de extensión a largo plazo, abierto (con enmascaramiento de la dosis), de eptinezumab en niños y adolescentes con migraña crónica o episódica.

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Estudio de fase i, multicéntrico, de un solo grupo, para evaluar la farmacocinética, la farmacodinámica y la seguridad de crovalimab en pacientes con nefritis lúpica.

  • Protocol code: CA43761
  • EudraCT code: 2021-004561-12
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Soler Romeo, Maria Jose
  • Research group:  Nefrologia i trasplantament renal
  • Service: Nefrologia
  • Phase: Fase I
  • Recruiting: Closed
  • Status: Open

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Estudio de fase 1/2, aleatorizado, sin enmascaramiento, en el que se evalúa ramucirumab en pacientes menores de edad y en adultos jóvenes con tumores desmoplásicos de células pequeñas y redondas recidivantes, recurrentes o resistentes al tratamiento

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HUMAN A L B U MIN TREATMENT IN ADULT SEPTICSHOCK. A PHASE 2, MULTICENTER, RANDOMIZED, CONTROLLEDSTUDY EVALUATING IMMUNE RESPONSE AND ORGAN FAILURE

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Estudio de extensión a largo plazo en fase III, multicéntrico, aleatorizado y de dosis ciega para evaluar la eficacia y la seguridad de BIIB059 de forma continua en participantes adultos con lupus eritematoso sistémico (LES) activo

  • Protocol code: 230LE306
  • EudraCT code: 2021-006378-22
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Cortes Hernandez, Josefina
  • Research group:  Reumatologia
  • Service: Reumatologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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A controlled, open-label post-authorisation efficacy and safety study in imlifidase desensitised kidney transplant patients with positive crossmatch against a deceased donor prior to imlifidase treatment, including non-comparative registry and concurrent reference cohorts

  • Protocol code: 20-HMedIdeS-19
  • EudraCT code: 2021-002640-70
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Bestard Matamoros, Oriol
  • Research group:  Nephrology and kidney transplantation
  • Service: Nephrology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio multicéntrico de extensión a largo plazo para evaluar la seguridad y la eficacia de GSK3196165 en el tratamiento de la artritis reumatoide

  • Protocol code: 209564
  • EudraCT code: 2019-000878-30
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Lopez Lasanta, Maria America
  • Research group:  Rheumatology
  • Service: Rheumatology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de extensión a largo plazo para evaluar la seguridad y la tolerabilidad de TAK-861 en participantes con trastornos seleccionados de hipersomnia central

  • Protocol code: TAK-861-2003
  • EudraCT code: 2022-002965-13
  • Pathology: Nervous system diseases
  • Principal investigator:  Romero Santo-Tomas, Odile
  • Research group:  Pneumology
  • Service: Neurofisiologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Ensayo doble ciego, aleatorizado, controlado con placebo, fase IIb sobre la eficacia y seguridad de comprimidos de ácido norursodesoxicólico en pacientes con esteatohepatitis no alcohólica (EHNA)

  • Protocol code: NUT-3/NAS
  • EudraCT code: 2018-003443-31
  • Pathology: Malalties del sistema digestiu
  • Principal investigator:  Pericàs Pulido, Juan Manuel
  • Research group:  Liver Diseases
  • Service: Hepatology
  • Phase: Phase II
  • Recruiting: Open
  • Status: Open

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Estudio de fase 2 abierto para evaluar la seguridad, tolerabilidad, farmacocinética y farmacodinámica de sotatercept (MK-7962) en niños de entre uno y menos de 18 años con HAP que reciben el tratamiento habitual.

  • Protocol code: MK-7962-008
  • EudraCT code: 2022-000478-25
  • Pathology: Diseases of the respiratory system
  • Principal investigator:  Moreno Galdó, Antonio
  • Research group:  Creixement i desenvolupament
  • Service: General Pediatrics and Specialties
  • Phase: Phase II
  • Recruiting: Open
  • Status: Open

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Inicio temprano de tratamiento con Candesartan vs Placebo en portadores genéticos de mutaciones causales de MCD sin evidencia de enfermedad (EARLY-GENE trial).

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Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.