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Ensayo clínico aleatorizado de no inferioridad para evaluar la eficacia de una dosis única y fija de 18 mg de ivermectina para el tratamiento de la estrongiloidiasis no complicada

  • Protocol code: STRONG-FIX
  • EudraCT code: 2022-004143-27
  • Pathology: Certes malalties infeccioses i parasitàries
  • Principal investigator:  Salvador Velez, Fernando M
  • Research group:  Malalties infeccioses
  • Service: Infeccioses
  • Phase: Fase II
  • Recruiting: Closed
  • Status: Iniciat

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
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Un ensayo de fase 2 de Gremubamab en comparación con placebo en participantes con bronquiectasias e infección crónica por Pseudomonas aeruginosa

  • Protocol code: GREAT-2
  • EudraCT code: 2022-003215-28
  • Pathology: Malalties del sistema respiratori
  • Principal investigator:  Polverino , Eva
  • Research group:  Pneumologia
  • Service: Pneumologia
  • Phase: Phase II
  • Recruiting: Open
  • Status: Tancat

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Un estudio piloto , multicéntrico, aleatorizado, no comparativo y de doble ciego de la terapia fágica en pacientes con infección de la articulación protésica de cadera o rodilla debida a Staphylococcus aureus tratados con DAIR y antibióticos.

  • Protocol code: PP-SA-001
  • EudraCT code: 2021-004469-11
  • Pathology: Certain infectious and parasitic diseases
  • Principal investigator:  Rodríguez Pardo, Ma Dolores
  • Research group:  Infectious Diseases
  • Service: Infectious
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Open

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Un ensayo clínico abierto y aleatorizado sobre la profilaxis de la infección por teicoplanina en pacientes pediátricos con leucemia mieloide aguda

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Ensayo aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia, farmacocinética y seguridad de remibrutinib (LOU064) a lo largo de 24 semanas en adolescentes de 12 a menos de 18 años de edad con urticaria crónica espontánea inadecuadamente controlada con antihistamínicos H1, seguido de una extensión opcional abierta de un máximo de otros 3 años y un período opcional de seguimiento de seguridad sin tratamiento a largo plazo de hasta 3 años adicionales.

  • Protocol code: CLOU064F12301
  • EudraCT code: No aplica
  • Pathology: Símptomes, signes i troballes anormals clíniques i de laboratori, no classificades enlloc més
  • Principal investigator:  Labrador Horrillo, Moisés
  • Research group:  Malalties sistèmiques
  • Service: Medicina Interna
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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A randomized, double-blind, placebo-controlled, phase 3 study to evaluate the efficacy and safety of fazirsiran in the treatment of Alpha-1 Antitrypsin deficiency–dssociated liver disease with METAVIR stage F2 to F4 fribrosis.

  • Protocol code: TAK-999-3001
  • EudraCT code: _
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Pons Delgado, Mònica
  • Research group:  Malalties hepàtiques
  • Service: Hepatologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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BRIGHT - A phase II, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of multiple doses of LT3001 drug product in subjects with Acute Ischemic Stroke (AIS)

  • Protocol code: LT3001-205
  • EudraCT code: _
  • Pathology: Malalties del sistema nerviós
  • Principal investigator:  Molina Cateriano, Carlos
  • Research group:  Recerca en ictus
  • Service: Neurologia
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Close

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Estudio de fase III, aleatorizado, doble ciego, controlado con placebo y de grupos paralelos para evaluar la eficacia y la seguridad de Iclepertin una vez al día durante un periodo de tratamiento de 26 semanas en pacientes con esquizofrenia (CONNEX-2)

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Estudio de fase 2, aleatorizado, en doble ciego, controlado con placebo y cruzado de dos vías,para evaluar la eficacia, seguridad y tolerabilidad de NMD670 en adultos deambulantes con atrofia espinal muscular detipo 3

  • Protocol code: NMD670-02-0001
  • EudraCT code: 2022-002301-24
  • Pathology: Nervous system diseases
  • Principal investigator:  Juntas Morales, Raul
  • Research group:  Sistema nerviós perifèric
  • Service: Neurology
  • Phase: Phase II
  • Recruiting: Open
  • Status: Open

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Obicetrapib y resultados cardiovasculares: estudio de fase III, aleatorizado, con doble enmascaramiento y comparativo con placebo para evaluar el efecto de 10 mg de obicetrapib en participantes con enfermedad cardiovascular aterosclerótica (ECVA) que no están bien controlados a pesar de recibir tratamientos antidislipidémicos en la dosis máxima tolerada

  • Protocol code: TA-8995-304
  • EudraCT code: 2021-005092-39
  • Pathology: Malalties del sistema circulatori
  • Principal investigator:  Lozano Torres, Jordi
  • Research group:  Malalties cardiovasculars
  • Service: Cardiologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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“A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in Subjects With Parkinson’s Disease With a Pathogenic Variant in the Glucocerebrosidase (GBA1) Gene

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A Multicenter, Adaptive, Randomized, Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections

  • Protocol code: INSIGHT 018 b
  • EudraCT code: No aplica
  • Pathology: Diseases of the respiratory system
  • Principal investigator:  Sánchez Montalvá, Adrián
  • Research group:  Infectious Diseases
  • Service: Infectious
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Open

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A Phase 3, Multicenter, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Obexelimab in Patients with IgG4-Related Disease

  • Protocol code: ZB012-03-001
  • EudraCT code: No aplica
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Martínez Valle, Fernando
  • Research group:  Systemic Diseases
  • Service: Internal Medicine
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Estudio de fase I/II, abierto y multicéntrico en el que se evalúan la seguridad, la eficacia y la cinética celular de YTB323 en participantes con trastornos autoinmunes refractarios graves.

  • Protocol code: CYTB323G12101
  • EudraCT code: 2022-001796-14
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Cortes Hernandez, Josefina
  • Research group:  Reumatologia
  • Service: Reumatologia
  • Phase: Phase II
  • Recruiting: Open
  • Status: Open

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Estudio de fase 2 aleatorizado de EQU-001 adyuvante para las crisis de inicio focal no controladas

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ESTUDIO DE FASE 2, DOBLE CIEGO, ALEATORIZADO, CONTROLADO CON PLACEBO, DE 4 GRUPOS PARA ESTUDIAR LOS SÍNTOMAS, LA FUNCIONALIDAD, LA CALIDAD DE VIDA RELACIONADA CON LA SALUD Y LA SEGURIDAD DE LA ADMINISTRACIÓN SUBCUTÁNEA REPETIDA DE PONSEGROMAB COMPARADO CON PLACEBO EN PARTICIPANTES ADULTOS CON INSUFICIENCIA CARDÍACA

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Ensayo de fase II, aleatorizado, sin enmascaramiento, controlado y multicéntrico del tratamiento de primera línea con células mesenquimales estromales MC0518 en comparación con el mejor tratamiento disponible en participantes pediátricos con enfermedad de injerto contra huésped aguda refractaria a esteroides después del trasplante alogénico de células madre

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Estudio multicéntrico, aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y la seguridad de CAL02 administrado por vía intravenosa conjuntamente con el tratamiento estándar en sujetos con neumonía bacteriana grave adquirida en la comunidad (SCABP)

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Estudio abierto sobre la seguridad y la eficacia del cenobamato (YKP3089) en pacientes pediátricos con crisis de inicio parcial (focales)

  • Protocol code: YKP3089C040
  • EudraCT code: 2020-005344-27
  • Pathology: Nervous system diseases
  • Principal investigator:  Raspall Chaure, Miquel
  • Research group:  Neurologia pediàtrica
  • Service: Pediatria General i Especialitats
  • Phase: Phase III
  • Recruiting: Open
  • Status: Open

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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Estudio de fase IIa, abierto y de dos grupos para evaluar el efecto de rilzabrutinib (PRN1008/SAR444671) sobre la seguridad y la actividad de la enfermedad en pacientes con enfermedad relacionada con la IgG4.

  • Protocol code: PRN1008-017/ACT17125
  • EudraCT code: 2022-002959-18
  • Pathology: Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
  • Principal investigator:  Martínez Valle, Fernando
  • Research group:  Systemic Diseases
  • Service: Internal Medicine
  • Phase: Phase II
  • Recruiting: Open
  • Status: Close

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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.