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16/09/2014

Vall d'Hebron establishes international basis for the management of respiratory infections in critical patients

2014_0188_IMATGE

16/09/2014

In the coming years, research will be focused in biomarkers, nebulised antibiotics and molecular diagnostic

Dr. Jordi Rello, head of the "http://www.vhir.org/larecerca/grupsrecerca/ca_grups_equip.asp?Idioma=en&mv1=2&mv2=1&mh1=2&mh2=1&mh3=1&mh4=0&ms=0&area=6&grup=3&menu=3" Intensive Care Service and the Clinical Research/Innovation in Pneumonia & Sepsis (CRIPS) group at Vall d’Hebron Institute of Research (VHIR), and head of the Intensive Care Service at the Hospital Universitari Vall d’Hebron, has set the foundations for a new model to guide the management of intensive care patients that have developed respiratory infections associated to mechanical ventilation. The conclusions of the study have been published at "http://www.thelancet.com/journals/lanres/article/PIIS2213-2600%2814%2970171-7/fulltext" The Lancet Respiratoy Medicine and have been presented recently at the "http://www.erscongress.org/" ERS International Congress , held in Munich, Germany.The researcher from VHIR and the Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), together with a researcher from the Hospital de Clinicas in Porto Alegre, Brasil, and a researcher from Brisbaine, Australia, has revised nearly a thousand articles published the last decade about pneumonia and tracheobronchitis caused by mechanical ventilation received in the ICU. Thanks to this basis, according to Dr. Rello, “the study establishes a new paradigm with the progress made the last 10 years that will guide a new approach to the managing of these patients in the next 5 or 10 years”.The infection of the airways is the main cause of antibiotic administration at the ICU and it usually presents in the form of severe sepsis or septic shock in patients that receive mechanical ventilation. The study shows that nearly 30 per cent of these infections evolve to pneumonia and the 70 per cent in tracheobronchitis, but finds that their differentiation is difficult because it depends on a lot of variables.The article describes for the first time the differences between the 8 main pathogens and shows how many days it takes pneumonia to appear after intubation, based on data not published of the largest European collaboration network in the study of this disease, the EUVAP.

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