Ariadna Laguna Tuset I am a neuroscientist with extensive experience in the molecular mechanisms underlying both neurodevelopmental and neurodegenerative diseases of the nervous system. My current research is aimed at identifying new therapeutic targets and biomarkers to improve the diagnosis and treatment of Parkinson's disease. Institutions of which they are part Main researcher Neurodegenerative Diseases Vall Hebron Institut de Recerca LinkedIn Twitter Orcid Email Ariadna Laguna Tuset LinkedIn Twitter Orcid Email Institutions of which they are part Main researcher Neurodegenerative Diseases Vall Hebron Institut de Recerca I am a neuroscientist with extensive experience in the molecular mechanisms underlying both neurodevelopmental and neurodegenerative diseases of the nervous system. My current research is aimed at identifying new therapeutic targets and biomarkers to improve the diagnosis and treatment of Parkinson's disease.
I received my Biology degree, Health and Life Sciences specialization, in 2003 at the Universitat Pompeu Fabra (Barcelona, Spain). I got my Ph.D. in 2008 in the laboratory of Dr. Mariona Arbonés at the Center for Genomic Regulation (CRG, Barcelona, Spain). My Ph.D. was devoted to study the molecular basis of Down Syndrome neurological alterations. In 2009, I joined the group of Professor Thomas Perlmann at the Ludwig Institute for Cancer Research – Karolinska Institutet (Stockholm, Sweden) as a post-doctoral Marie Curie researcher to work on the transcriptional regulation of dopamine neurons during development and in pathological conditions such as Parkinson’s disease. In 2014, I moved back to Barcelona and joined the Neurodegenerative Diseases Research Group at the Vall d’Hebron Research Institute (VHIR) as a Beatriu de Pinós post-doctoral researcher funded by AGAUR-FP7 Marie Curie Actions. Afterwards, I received a Young Investigator contract from the Spanish government (Ministry of Economy and Competitiveness (MINECO)) and a Junior Leader fellowship from the La Caixa Foundation to establish my own research lines within the group. In addition, I am an associate researcher at the Neuroscience Institute of the Autonomous University of Barcelona (UAB) and Scientific Ambassador of the World Parkinson Coalition. The research from my team is devoted to elucidate the molecular mechanisms of inter-organ communication in Parkinson’s disease and how this contributes to the pathophysiology and symptoms of this neurodegenerative disorder. Our research contributes to: (i) identify biomarkers for early detection, disease progression or response to treatment, (ii) identify new molecular targets and develop novel therapeutic strategies with disease-modifying potential, (iii) unravel molecular pathways common to other neurodegenerative or metabolic diseases. Researcher ID: F-9561-2016; Orcid: 0000-0002-9732-6677.
Research lines Identification of biomarkers of prodromal Parkinson's disease Despite intensive efforts towards understanding the aetiology/pathogenesis of Parkinson's disease (PD) and the development of novel therapeutic approaches for this neurodegenerative condition, the current treatment for PD remains symptomatic and yet far from modifying disease onset or progression. Before the manifestation of the classical motor symptoms, PD patients present with non-motor symptoms in a prodromal phase. The identification of deregulated molecular pathways or genes in peripheral blood and/or cerebrospinal fluid from these prodromal patients may help develop potential biomarkers for the early detection, diagnosis, risk assessment and/or progression of PD, which are currently lacking, as well as to stratify patients at very early stages to apply more specific, personalized disease-modifying treatments. IP: Miquel Vila Bover, Ariadna Laguna Tuset Projects PAIR: Parkinson’s Intergenerational Care IP: Ariadna Laguna Tuset Collaborators: - Funding agency: EUROPEAN COMMISSION Funding: 20000 Reference: EC/IMPETUS/2024/LAGUNA Duration: 07/06/2024 - 17/01/2025 diVHulga. Programa anual de actividades UCC+I del Campus Vall d’Hebron (VH) IP: Immaculada Hernández Rodríguez Collaborators: Josep Quer Sivila, Sara Ruiz Gallardo, Mayte Serrat Lopez, Julia Basallote Garciade Quiros, Beatriz Blasco Perez, Ariadna Laguna Tuset, Diana Fernandes de Rafael Funding agency: Fundación Española Ciencia y Tecnología (FECYT) Funding: 30000 Reference: FCT-23-19812 Duration: 01/07/2024 - 30/06/2025 Tejiendo Ciencia IP: Ariadna Laguna Tuset Collaborators: Anna Santamaria Margalef, Maria Mar Hernandez Guillamon, Sara Mas Assens Funding agency: Fundación Española Ciencia y Tecnología (FECYT) Funding: 15000 Reference: FCT-2023-19804 Duration: 01/12/2024 - 30/11/2025 The brain-body axis in Parkinson's disease for biomarker and therapeutic development (BRAIN-BODY-PD) IP: Ariadna Laguna Tuset Collaborators: - Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 199998.14 Reference: CNS2023-145555 Duration: 01/04/2024 - 31/03/2026 Pagination Current page 1 Page 2 Page 3 Page 4 Next page › Last page »
