Maria Vicario Perez Institutions of which they are part Main researcher Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca Email Maria Vicario Perez Email Institutions of which they are part Main researcher Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca
Research lines Translational mucosal immunology Mucosal surfaces of the gastrointestinal, bronchopulmonary, and genitourinary tracts constitute the most prominent site of interaction between the host and the external habitat and a real hub where microbes and the host bi-directionally communicate through mechanisms that engage the activation of the immune and nervous systems. Barrier mechanisms have evolved early in evolution, and consist of a number of anatomical and functional elements distributed across the tissue layers, which tightly interact to maintain homeostasis. The mucosal immune system develops fundamental defensive and homeostatic duties at mucosal sites through activation of innate and adaptive immunity and the development of tolerogenic responses against harmless antigens. Immune responses also include the resolution of inflammation to avoid tissue damage after antigen penetration. However, uncontrolled immune activity is associated with mucosal barrier failure and organ dysfunction, which characterize most organic and functional disorders. The major goal of the Translational Mucosal Immunology lab is to further identify the role of specific immune cells (mast cells, eosinophils and B cells) as major players in the control of mucosal barrier mechanisms in health and disease. Our approach to translational research in digestive diseases involves the development of preclinical and clinical studies aimed at identifying biomarkers of gastrointestinal dysfunction and gut health. IP: Maria Vicario Perez Projects Fisiologia i fisiopatologia digestiva IP: Fco Javier Santos Vicente Collaborators: Maria Vicario Perez, Beatriz Lobo Alvarez, Fernando Azpiroz Vidaur, Natalia Borruel Sainz, Francesc Xavier Molero Richard, Francesc Casellas Jordá, Carmen Alonso Cotoner, Carolina Malagelada Prats, Jorge Serra Pueyo, Ana Maria Gonzalez Castro, Ariadna Aguilar Cayuelas, Elba Exposito Fernandez, Laura Campderros Traver, Blanca Grases Pintó, Virginia Robles Alonso, Adoración Nieto Ruiz, Claudia Barber Caselles, Elena Céspedes Martínez, Danila Guagnozzi, Ronald Benjamin Llerena Castro, Francisca Yañez Araya, Consuelo Cammarota Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 40000 Reference: 2021 SGR 00766 Duration: 01/01/2022 - 30/06/2025 Interacción neuro-epitelial inducida por el exposoma intestinal y su contribución a la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica IP: Maria Vicario Perez Collaborators: Judit Álvarez González Funding agency: Instituto de Salud Carlos III Funding: 20700 Reference: MV21/00097 Duration: 12/08/2022 - 31/01/2023 Disfunción neuroepitelial intestinal en la fisiopatología del síndrome del intestino irritable. IP: Maria Vicario Perez Collaborators: - Funding agency: Instituto de Salud Carlos III Funding: 82400 Reference: FI20/00256 Duration: 01/02/2021 - 31/03/2023 Contribución diferencial del epitelio intestinal a la fisiopatología de la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica. Perfil clínico-biológico para el diagnóstico diferencial. IP: Maria Vicario Perez Collaborators: Beatriz Lobo Alvarez, Merce Albert Bayo, Inés de Torres Ramirez, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Xavier Serra Ruiz Funding agency: Instituto de Salud Carlos III Funding: 183920 Reference: PI19/01643 Duration: 01/01/2020 - 30/06/2024 Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Next page › Last page »
