Maria Vicario Perez Institucions de les que formen part Investigador/a principal Fisiologia i fisiopatologia digestiva Vall Hebron Institut de Recerca Email Maria Vicario Perez Email Institucions de les que formen part Investigador/a principal Fisiologia i fisiopatologia digestiva Vall Hebron Institut de Recerca
Línies de recerca Translational mucosal immunology Mucosal surfaces of the gastrointestinal, bronchopulmonary, and genitourinary tracts constitute the most prominent site of interaction between the host and the external habitat and a real hub where microbes and the host bi-directionally communicate through mechanisms that engage the activation of the immune and nervous systems. Barrier mechanisms have evolved early in evolution, and consist of a number of anatomical and functional elements distributed across the tissue layers, which tightly interact to maintain homeostasis. The mucosal immune system develops fundamental defensive and homeostatic duties at mucosal sites through activation of innate and adaptive immunity and the development of tolerogenic responses against harmless antigens. Immune responses also include the resolution of inflammation to avoid tissue damage after antigen penetration. However, uncontrolled immune activity is associated with mucosal barrier failure and organ dysfunction, which characterize most organic and functional disorders. The major goal of the Translational Mucosal Immunology lab is to further identify the role of specific immune cells (mast cells, eosinophils and B cells) as major players in the control of mucosal barrier mechanisms in health and disease. Our approach to translational research in digestive diseases involves the development of preclinical and clinical studies aimed at identifying biomarkers of gastrointestinal dysfunction and gut health. IP: Maria Vicario Perez Projectes Fisiologia i fisiopatologia digestiva IP: Fco Javier Santos Vicente Col·laboradors: Maria Vicario Perez, Beatriz Lobo Alvarez, Fernando Azpiroz Vidaur, Natalia Borruel Sainz, Francesc Xavier Molero Richard, Francesc Casellas Jordá, Carmen Alonso Cotoner, Carolina Malagelada Prats, Jorge Serra Pueyo, Ana Maria Gonzalez Castro, Ariadna Aguilar Cayuelas, Elba Exposito Fernandez, Laura Campderros Traver, Blanca Grases Pintó, Virginia Robles Alonso, Adoración Nieto Ruiz, Claudia Barber Caselles, Elena Céspedes Martínez, Danila Guagnozzi, Ronald Benjamin Llerena Castro, Francisca Yañez Araya, Consuelo Cammarota Entitat finançadora: Agència Gestió Ajuts Universitaris i de Recerca Finançament: 40000 Referència: 2021 SGR 00766 Durada: 01/01/2022 - 30/06/2025 Interacción neuro-epitelial inducida por el exposoma intestinal y su contribución a la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica IP: Maria Vicario Perez Col·laboradors: Judit Álvarez González Entitat finançadora: Instituto de Salud Carlos III Finançament: 20700 Referència: MV21/00097 Durada: 12/08/2022 - 31/01/2023 Disfunción neuroepitelial intestinal en la fisiopatología del síndrome del intestino irritable. IP: Maria Vicario Perez Col·laboradors: - Entitat finançadora: Instituto de Salud Carlos III Finançament: 82400 Referència: FI20/00256 Durada: 01/02/2021 - 31/03/2023 Contribución diferencial del epitelio intestinal a la fisiopatología de la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica. Perfil clínico-biológico para el diagnóstico diferencial. IP: Maria Vicario Perez Col·laboradors: Beatriz Lobo Alvarez, Merce Albert Bayo, Inés de Torres Ramirez, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Xavier Serra Ruiz Entitat finançadora: Instituto de Salud Carlos III Finançament: 183920 Referència: PI19/01643 Durada: 01/01/2020 - 30/06/2024 Paginació Pàgina actual 1 Page 2 Page 3 Page 4 Page 5 Pàgina següent › Última pàgina »
