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Meritxell Genesca Ferrer

I am a senior investigator at the infectious diseases department where I lead projects focused on defining protective immune responses against pathogens in order to develop new therapies. I have mainly worked on cervicovaginal mucosa immunity, a tissue with a high impact on public health as the portal of entry for sexually transmitted infections such as HIV. The knowledge acquired during my scientific career has served to expand my research towards the understanding of immune protection against pathogens in other tissues, such as against SARS-CoV-2 in the lung.

Institutions of which they are part

Main researcher
Infectious Diseases
Vall Hebron Institut de Recerca

Meritxell Genesca Ferrer

Institutions of which they are part

Main researcher
Infectious Diseases
Vall Hebron Institut de Recerca

I am a senior investigator at the infectious diseases department where I lead projects focused on defining protective immune responses against pathogens in order to develop new therapies. I have mainly worked on cervicovaginal mucosa immunity, a tissue with a high impact on public health as the portal of entry for sexually transmitted infections such as HIV. The knowledge acquired during my scientific career has served to expand my research towards the understanding of immune protection against pathogens in other tissues, such as against SARS-CoV-2 in the lung.

Dr. Meritxell Genescà is an expert on cervical mucosal immunology and infectious diseases. She obtained the Extraordinary Award from the Autonomous University of Barcelona as a Doctor in Veterinary Medicine (2000). After obtaining her PhD in physiology (2001-2004, IIBB-CSIC), she was contracted by the University of California first as a postdoctoral researcher and then as an Associate Researcher Immunologist. For the next six years, she worked on the top animal model for HIV sexual transmission studies and specialized in mucosal immunology. In 2011, she joined the Institut d’Investigació Germans Trias i Pujol in Badalona, through a Ramón y Cajal contract, before moving to her current institution in 2017. Dr. Genescà is interested on defining the nature of protective immune responses against pathogens that use the cervicovaginal mucosa as their portal of entry, such as HIV. Her group collaborates with several basic and clinical research groups in order to conduct translational comparative medicine in the following areas: 1) HIV reservoir characterization in the cervical tissue and new strategies for its elimination; 2) Sexually Transmitted Infections and increased risk of co-infection; 3) Adjuvants and biomarkers of mucosal immunity; 4) Tissue explant models to study host-pathogen interaction and immunity (including SARS-CoV-2).
She is a member of the international Society for Mucosal Immunology (SMI), the Spanish group for AIDS study (GESIDA) and the Spanish HIV/AIDS Network (RIS). Moreover, she has participated in many dissemination activities, such as career orientation and continuous education for seniors, among others. Her track record includes over 35 articles in major international scientific journals (https://orcid.org/0000-0001-6413-3812) with an h-index of 20, numerous presentations in international meetings and several fellowships and awards. She is also actively involved in teaching and student training.

Projects

Malalties infeccioses

IP: Vicenç Falcó Ferrer
Collaborators: Jose Santos Santiago, Maria Luisa Aznar Ruiz de Alegria, Adria Curran Fàbregas, Jorge Nestor Garcia Perez, Oscar Len Abad, Mª Carmen Ferrer Barberà, Javier Gomis Rodriguez, Diana Pou Ciruelo, Begoña Treviño Maruri, Nuria Fernández Hidalgo, Joan Gavaldà Santapau, Juan Espinosa Pereiro, Bibiana Planas Ribas, Ma Dolores Rodríguez Pardo, Pau Bosch Nicolau, David Perea Pérez, Israel Molina Romero, Patricia Álvarez López, Vicente Descalzo Jorro, Marta Sanchiz Cruz, Nuria Serre Delcor, Julia Sellares Nadal, Fernando M Salvador Velez, Isabel Ruiz Camps, Jordi Gómez i Prat, María José Buzón Gómez, Hakima Ouaarab Essadek, Paula Suanzes Diez, Jordi Navarro Mercadé, Esperanza Esteban Serna, Raisa Morales Martinez, Joaquin Burgos Cibrian, Nerea Sanchez Gaona, Joan Rey Cano, Adrián Sánchez Montalvá, Cristina Mancebo Perez, Montserrat Llinás Vidal, Malalties infeccioses, Maider Arando Lasagabaster, Ibai Los Arcos Bertiz, Claudia Broto Cortes, Meritxell Genesca Ferrer, Ines Mercedes Oliveira Souto, Silvina Andrea Magnani, Yasmine Margaret Baktash
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00764
Duration: 01/01/2022 - 30/06/2025

Plataformas basadas en la immunologia de las mucosas para el desarrollo de vacunas de nueva generación

IP: Meritxell Genesca Ferrer
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 199287
Reference: CNS2022-135549
Duration: 01/09/2023 - 31/08/2025

Ministerio de Ciencia

Charting SARS-CoV-2 entry factors in human tissues

IP: Meritxell Genesca Ferrer
Collaborators: David Perea Pérez, María José Buzón Gómez, Charting SARS-CoV-2 entry factors in human tissues
Funding agency: Fundació La Marató de TV3
Funding: 138750
Reference: 2021121
Duration: 23/09/2021 - 22/09/2023

Induction of CD8+ Resident Memory T cell phenotypes to eliminate viral reservoirs

IP: Meritxell Genesca Ferrer
Collaborators: -
Funding agency: GILEAD SCIENCES SLU
Funding: 49997.2
Reference: GLD21-00049
Duration: 01/07/2022 - 31/12/2024

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