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Biomedical Research in Melanoma

The Biomedical Research in Melanoma group is interested in skin cancer. We investigate the molecular causes for these diseases to design effective therapies against them. Our research is done in close proximity to patients, where our goal is to translate our discoveries as fast as possible to the clinic. To that end, we have a multidisciplinary group that associate dermatologists, oncologists, pathologists and basic-scientists that ask relevant clinical questions that need biological answers.

Our workflow contemplates information obtained from patients (genetic information, clinical history, functional data…) that is translated into animal models (genetic modified mouse models, PDX…) and in vitro experiments to answer the formulated questions. These results are used to design novel therapeutic approaches, including drug development and preclinical studies that ultimately will be translated to patients. 

The main lines of investigation are: 
•    Molecular mechanisms involved in melanoma development and progression, 
•    Targeting metabolism for melanoma treatment,
•    The mechanisms of resistance to immunotherapy.
 

Team

Gabriela Gomez Andrade

Gabriela Gomez Andrade

Research technician
Biomedical Research in Melanoma
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Kimberley Anne McGrail Fernández

Kimberley Anne McGrail Fernández

Postdoctoral researcher
Biomedical Research in Melanoma
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Pablo Marino Castro Garcia

Pablo Marino Castro Garcia

Research assistant
Biomedical Research in Melanoma
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Paula Granado Martinez

Paula Granado Martinez

Postdoctoral researcher
Biomedical Research in Melanoma
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Vicente García-Patos Briones

Vicente García-Patos Briones

Head of group
Biomedical Research in Melanoma
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Gabriela Gomez Andrade

Gabriela Gomez Andrade

Research technician
Biomedical Research in Melanoma
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Kimberley Anne McGrail Fernández

Kimberley Anne McGrail Fernández

Postdoctoral researcher
Biomedical Research in Melanoma
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Pablo Marino Castro Garcia

Pablo Marino Castro Garcia

Research assistant
Biomedical Research in Melanoma
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Paula Granado Martinez

Paula Granado Martinez

Postdoctoral researcher
Biomedical Research in Melanoma
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Vicente García-Patos Briones

Vicente García-Patos Briones

Head of group
Biomedical Research in Melanoma
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Projects

Recerca biomèdica and melanomes mod anim i càncer

IP: Juan Angel Recio Conde
Collaborators: Paula Granado Martinez, Kimberley Anne McGrail Fernández, Carlos González Cruz, Vicente García-Patos Briones
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00653
Duration: 01/01/2022 - 30/06/2025

Novel therapeutic topical approach for discoid lupus cutaneous (DLE) treatment

IP: Cristina Solé Marce
Collaborators: Berta Ferrer Fábrega, Gloria Aparicio Español
Funding agency: Instituto de Salud Carlos III
Funding: 99099
Reference: PI21/01869
Duration: 01/01/2022 - 31/12/2025

Publications

Sentinel lymph node biopsy versus observation in high-risk cutaneous squamous cell carcinoma in immunosuppressed and immunocompetent patients: An inverse probability of treatment weighting study.

PMID: 38738666
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2024
Reference: J Eur Acad Dermatol Venereol. 2024 May 13. doi: 10.1111/jdv.20051.
Impact factor:
Publication type: Paper in international publication
Authors: Almazan-Fernandez, Francisco M; Avallone, Gianluca; Canueto, Javier; Carrasco, Cristian; Del Rio, Maria; Ferrandiz-Pulido, Carla; Ferrer-Fuertes, Ada; Fuente, Maria J; Gomez-Tomas, Alvaro; Jaka, Ane et al.
DOI: 10.1111/jdv.20051

Vitiligo-like basal cell carcinoma: An emerging entity in young women.

PMID: 38841972
Journal: Indian Journal of Dermatology Venereology & Leprology
Year: 2024
Reference: Indian J Dermatol Venereol Leprol. 2024 Apr 16:1-3. doi: 10.25259/IJDVL_672_2023.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Bassas-Freixas, Patricia; Bodet, Domingo; Falguera-Mayoral, Marc; Ferrer-Fabrega, Berta; Garcia-Patos, Vicente; Gomez-Tomas, Alvaro; Palao-Domenech, Ricard et al.
DOI: 10.25259/IJDVL_672_2023

The "Personalising Actinic Keratosis Treatment for Immunocompromised Patients" (IM-PAKT) Project: An Expert Panel Opinion.

PMID: 38902589
Journal: Dermatology and Therapy
Year: 2024
Reference: Dermatol Ther (Heidelb). 2024 Jun 21. doi: 10.1007/s13555-024-01215-y.
Impact factor:
Publication type: Paper in international publication
Authors: Ferrandiz-Pulido, Carla; Haedersdal, Merete; Hofbauer, Gunther F L; Lear, John Thomas; Lebbe, Celeste; Piaserico, Stefano; Szeimies, Rolf-Markus; Ulrich, Claas et al.
DOI: 10.1007/s13555-024-01215-y

Different mutational profiles of subcutaneous panniculitis-like T-cell lymphoma and lupus panniculitis: an additional case series.

PMID: 39032781
Journal:
Year: 2024
Reference: Actas Dermosifiliogr. 2024 Jul 18:S0001-7310(24)00595-7. doi: 10.1016/j.ad.2024.06.006.
Impact factor:
Publication type: Paper in international publication
Authors: Afonso-Martin, J L; Alonso-Alonso, R; Borregon, J; Cereceda, L; Cerroni, L; Chamizo, C; de la Fuente, L; Diaz de la Pinta, F J; Estrach, T; Ferrer, B et al.
DOI: 10.1016/j.ad.2024.06.006

Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients With Advanced Skin Cancers-Emerging Strategies for Clinical Management.

PMID: 36706163
Journal: TRANSPLANTATION
Year: 2023
Reference: Transplantation. 2023 Jul 1;107(7):1452-1462. doi: 10.1097/TP.0000000000004459. Epub 2023 Jun 20.
Impact factor:
Publication type: Review in international publication
Authors: Bouwes Bavinck, Jan Nico; Del Marmol, Veronique; Ferrandiz-Pulido, Carla; Geusau, Alexandra; Guthoff, Martina; Harwood, Catherine; Lebbe, Celeste; Leiter, Ulrike; Meyer, Thomas; Nageli, Mirjam C et al.
DOI: 10.1097/TP.0000000000004459

Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study.

PMID: 37901848
Journal: HemaSphere
Year: 2023
Reference: Hemasphere. 2023 Oct 24;7(11):e966. doi: 10.1097/HS9.0000000000000966. eCollection 2023 Nov.
Impact factor:
Publication type: Paper in international publication
Authors: Ara-Martin, M; Arias-Santiago, S; Botella-Estrada, R; Canueto, J; Carrascosa-Carrillo, J M; Carretero-Hernandez, G; Coto-Segura, P; de Eusebio-Murillo, E; Deheshi, Samineh; Descalzo, M A et al.
DOI: 10.1097/HS9.0000000000000966

Prognostic factors of satellitosis or in-transit metastasis in cutaneous squamous cell carcinoma. A multicentric cohort study.

PMID: 36907554
Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Year: 2023
Reference: J Am Acad Dermatol. 2023 Jul;89(1):119-127. doi: 10.1016/j.jaad.2023.02.048. Epub 2023 Mar 10.
Impact factor:
Publication type: Paper in international publication
Authors: Abril-Perez, Carlos; Aguayo-Ortiz, Rafael S; Altemir-Vidal, Arcadi; Bea-Ardebol, Sonia; Becerril, Sara; Bodet-Castillo, Domingo; Botella-Estrada, Rafael; Canueto, Javier; Deza, Gustavo; Ferrandiz-Pulido, Carla et al.
DOI: 10.1016/j.jaad.2023.02.048

Therapeutic Outcomes and Survival Analysis of Extramammary Paget's Disease: A multicentre retrospective study of 249 patients.

PMID: 37704106
Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Year: 2023
Reference: J Am Acad Dermatol. 2023 Sep 11:S0190-9622(23)02690-7. doi: 10.1016/j.jaad.2023.08.088.
Impact factor:
Publication type: Paper in international publication
Authors: Aguayo-Ortiz, Rafael S; Alcaraz, Inmaculada; Arandes-Marcocci, Jorge; Barchino-Ortiz, Lucia; Bea-Ardebol, Sonia; Delgado, Yolanda; Deza, Gustavo; Dradi, Giulia Greta; Escola, Helena; Escola-Rodriguez, Alba et al.
DOI: 10.1016/j.jaad.2023.08.088

Lipoblastoma-like tumor of the vulva: A case report and review of the literature.

PMID: 35483770
Journal: Revista espanola de patologia
Year: 2022
Reference: Rev Esp Patol. 2022 Apr-Jun;55(2):139-144. doi: 10.1016/j.patol.2019.10.001. Epub 2020 Jan 2.
Impact factor:
Publication type: Paper in national publication
Authors: Bodet, Domingo; Delbene, Clara; Ferrer, Berta; Ramon Y Cajal, Santiago; Rivas, Antoni; Romagosa, Cleofe; Valverde, Claudia; Vasquez-Dongo, Carmen et al.
DOI: 10.1016/j.patol.2019.10.001

Clinical and pathological features of Merkel cell carcinoma: A 4-year follow-up observational retrospective study in Spain.

PMID: 34922051
Journal: Cancer Epidemiology
Year: 2022
Reference: Cancer Epidemiol. 2022 Feb;76:102081. doi: 10.1016/j.canep.2021.102081. Epub 2021 Dec 15.
Impact factor:
Publication type: Paper in international publication
Authors: Aneiros-Fernandez, Jose; Ayala, Maria; Barranco, Carlos; Beato, Maria Jose; Carrillo, Rosario; Cordoba, Alicia; de Las Penas, Ramon; Fernandez-Figueras, Maria Teresa; Ferrer, Berta; Fraga-Fernandez, Javier et al.
DOI: 10.1016/j.canep.2021.102081

Prurigiform angiomatosis: report of three cases and review of the literature.

PMID: 35781803
Journal: INTERNATIONAL JOURNAL OF DERMATOLOGY
Year: 2022
Reference: Int J Dermatol. 2022 Jul 3. doi: 10.1111/ijd.16345.
Impact factor: 2.736
Publication type: Letter or abstract
Authors: Fernandez-Figueras, Maria-Teresa; Garcia-Patos Briones, Vicente; Perez-Munoz, Noelia; Barrabes-Torrella, Cristina; Salleras-Redonnet, Montse; Quintana-Codina, Monica; Gonzalez-Cruz, Carlos et al.
DOI: 10.1111/ijd.16345

Consensus-Based Recommendations on the Prevention of Squamous Cell Carcinoma in Solid Organ Transplant Recipients: A Delphi Consensus Statement.

PMID: 34468690
Journal: JAMA Dermatology
Year: 2021
Reference: JAMA Dermatol. 2021 Oct 1;157(10):1219-1226. doi: 10.1001/jamadermatol.2021.3180.
Impact factor:
Publication type: Paper in international publication
Authors: Arron, Sarah T; Asgari, Maryam M; Billingsley, Elizabeth; Blalock, Travis W; Blasdale, Katie; Bouwes Bavinck, Jan Nico; Carroll, Bryan T; Carucci, John A; Chong, Alvin H; Christensen, Sean R et al.
DOI: 10.1001/jamadermatol.2021.3180

Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis.

PMID: 34299025
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2021
Reference: Int J Mol Sci. 2021 Jul 9;22(14). pii: ijms22147406. doi: 10.3390/ijms22147406.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Shahrour, Fatima; Amor Lopez, Ana; Capuano, Alessandra; Doliana, Roberto; Hergueta-Redondo, Marta; Mazariegos, Marina S; Megias, Diego; Munoz, Eva; Munoz, Javier; Peinado, Hector et al.
DOI: 10.3390/ijms22147406

Posttransplant Kaposi sarcoma: Analysis of a series of 13 patients.

PMID: 34246484
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 Oct 8;157(7):339-343. doi: 10.1016/j.medcli.2021.04.030. Epub 2021 Jul 7.
Impact factor:
Publication type: Letter or abstract
Authors: Ferrandiz-Pulido, Carla; Ferrer Fabregas, Berta; Garcia-Patos Briones, Vicente; Gonzalez-Cruz, Carlos et al.
DOI: 10.1016/j.medcli.2021.04.030

Long-term results of sirolimus treatment in lymphangioleiomyomatosis: a single referral centre experience.

PMID: 33986388
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 May 13;11(1):10171. doi: 10.1038/s41598-021-89562-0.
Impact factor:
Publication type: Paper in international publication
Authors: Bello, Irene; Berastegui, Cristina; Bravo, Carlos; Burgos, Rosa; Escobar, Roser; Ferrandiz-Pulido, Carla; Gomez, Alba; Gomez-Olles, Susana; Lopez-Meseguer, Manuel; Mendez, Alejandra et al.
DOI: 10.1038/s41598-021-89562-0

Severe Autoinflammatory Manifestations and Antibody Deficiency Due to Novel Hypermorphic PLCG2 Mutations.

PMID: 32671674
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2020
Reference: J Clin Immunol. 2020 Oct;40(7):987-1000. doi: 10.1007/s10875-020-00794-7. Epub 2020 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Alsina, Laia; Anton, Maria Carmen; Arostegui, Juan I; Basagana, Maria; Bull, Daniel; Bunney, Tom D; Casals, Ferran; Colobran, Roger; Deya, Angela; Esteve-Sole, Ana et al.
DOI: 10.1007/s10875-020-00794-7

Efficacy of Thalidomide in Discoid Lupus Erythematosus: Insights into the Molecular Mechanisms.

PMID: 32659758
Journal: DERMATOLOGY
Year: 2020
Reference: Dermatology. 2020;236(5):467-476. doi: 10.1159/000508672. Epub 2020 Jul 13.
Impact factor:
Publication type: Review in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Ordi-Ros, Josep; Sole, Cristina et al.
DOI: 10.1159/000508672

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.

PMID: 32647375
Journal: Communications Biology
Year: 2020
Reference: Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0.
Impact factor:
Publication type: Paper in international publication
Authors: Canals, Francesc; Espinosa-Gil, Sergio; Ferrer, Berta; Garcia-Ortega, Sara; Garcia-Patos, Vicenc; Gil, Rosa; Gonzalez-Sanchez, Elena; Granado-Martinez, Paula; Grueso, Judit; Hernandez-Losa, Javier et al.
DOI: 10.1038/s42003-020-1092-0

Estimated Effect of COVID-19 Lockdown on Skin Tumor Size and Survival: An Exponential Growth Model.

PMID: 32513393
Journal: Actas dermo-sifiliograficas
Year: 2020
Reference: Actas Dermosifiliogr. 2020 Oct;111(8):629-638. doi: 10.1016/j.ad.2020.05.001. Epub 2020 May 11.
Impact factor:
Publication type: Review in national publication
Authors: Almazan, F; Canueto, J; Ferrandiz-Pulido, C; Fuente, M J; Jaka, A; Moreno-Ramirez, D; Nagore, E; Podlipnik, S; Ribero, S; Sanmartin, O et al.
DOI: 10.1016/j.ad.2020.05.001

Management of Kaposi Sarcoma after Solid Organ Transplantation: a European Retrospective Study.

PMID: 30902727
Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Year: 2019
Reference: J Am Acad Dermatol. 2019 Aug;81(2):448-455. doi: 10.1016/j.jaad.2019.03.028. Epub 2019 Mar 19.
Impact factor:
Publication type: Paper in international publication
Authors: Barete, Stephane; Bouwes-Bavinck, Jan Nico; Del Marmol, Veronique; Delyon, Julie; Euvrard, Sylvie; Ferrandiz-Pulido, Carla; Frances, Camille; Gulec, A Tulin; Harwood, Catherine A; Lebbe, Celeste et al.
DOI: 10.1016/j.jaad.2019.03.028

Indurated Papules on the Face.

PMID: 30850121
Journal: Actas dermo-sifiliograficas
Year: 2019
Reference: Actas Dermosifiliogr. 2019 Sep;110(7):599-600. doi: 10.1016/j.ad.2018.01.018. Epub 2019 Mar 6.
Impact factor:
Publication type: Paper in national publication
Authors: Cabezas Calderon, V; Garcia-Patos Briones, V; Gonzalez-Cruz, C et al.
DOI: 10.1016/j.ad.2018.01.018

Immunotherapy in Nonmelanoma Skin Cancer.

PMID: 30837075
Journal: Actas dermo-sifiliograficas
Year: 2019
Reference: Actas Dermosifiliogr. 2019 Jun;110(5):353-359. doi: 10.1016/j.ad.2018.09.013. Epub 2019 Mar 2.
Impact factor:
Publication type: Review in national publication
Authors: Aparicio Espanol, G; Bassas Freixas, P; Garcia-Patos Briones, V et al.
DOI: 10.1016/j.ad.2018.09.013

Vitamin D deficiency in solid-organ transplant recipients from a Spanish Mediterranean population.

PMID: 30701578
Journal: CLINICAL AND EXPERIMENTAL DERMATOLOGY
Year: 2019
Reference: Clin Exp Dermatol. 2019 Jun;44(4):e103-e109. doi: 10.1111/ced.13915. Epub 2019 Jan 30.
Impact factor:
Publication type: Paper in international publication
Authors: Berastegui, C; Castells, L; Ferrandiz-Pulido, C; Garcia-Patos, V; Juarez-Dobjanschi, C; Moreso, F; Torres, I B; Zarzoso-Munoz, I et al.
DOI: 10.1111/ced.13915

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence.

PMID: 29944140
Journal: JOURNAL OF CLINICAL INVESTIGATION
Year: 2018
Reference: J Clin Invest. 2018 Aug 31;128(9):3887-3905. doi: 10.1172/JCI96393. Epub 2018 Aug 6.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Susana; Argiles, Guillem; Arques, Oriol; Arroyo, Alicia G; Caratu, Ginevra; Casanovas, Oriol; Chicote, Irene; Cuesta-Borras, Estefania; Dienstmann, Rodrigo; Eguizabal, Cristina et al.
DOI: 10.1172/JCI96393

Genetic Profiles of Squamous Cell Carcinomas Associated with Recessive Dystrophic Epidermolysis Bullosa Unveil NOTCH and TP53 Mutations and an Increased MYC Expression.

PMID: 29291383
Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY
Year: 2018
Reference: J Invest Dermatol. 2018 Jun;138(6):1423-1427. doi: 10.1016/j.jid.2017.12.026. Epub 2017 Dec 29.
Impact factor:
Publication type: Paper in international publication
Authors: Bodet, D; Caratu, G; Ferrer, B; Garcia-Patos, V; Gonzalez-Sanchez, E; Hernandez-Losa, J; Mancuso, F; McGrail, K; Perez-Alea, M; Recio, J A et al.
DOI: 10.1016/j.jid.2017.12.026

PD-L1 Expression is Increased in Metastasizing Squamous Cell Carcinomas and Their Metastases.

PMID: 29742559
Journal: AMERICAN JOURNAL OF DERMATOPATHOLOGY
Year: 2018
Reference: Am J Dermatopathol. 2018 Sep;40(9):647-654. doi: 10.1097/DAD.0000000000001164.
Impact factor:
Publication type: Paper in international publication
Authors: Andrades, Evelyn; Ferrandiz-Pulido, Carla; Garcia-Diez, Irene; Garcia-Patos, Vicenc; Gimeno, Javier; Hernandez-Munoz, Inmaculada; Hernandez-Ruiz, Eugenia; Pujol, Ramon M; Toll, Agusti; Yebenes, Mireia et al.
DOI: 10.1097/DAD.0000000000001164

Early evolutionary divergence between papillary and anaplastic thyroid cancers.

PMID: 29648575
Journal: ANNALS OF ONCOLOGY
Year: 2018
Reference: Ann Oncol. 2018 Jun 1;29(6):1454-1460. doi: 10.1093/annonc/mdy123.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez, C; Cameselle-Teijeiro, J M; Capdevila, J; Caratu, G; Hernando, J; Iglesias, C; Mancuso, F F; Matias-Guiu, X; Matos, I; Mayor, R et al.
DOI: 10.1093/annonc/mdy123

Use of Molecular Biology Techniques in Sarcoidal Granulomatous Dermatitis: A Clinicopathological and Molecular Approach with Diagnostic Implications.

PMID: 28681062
Journal: ACTA DERMATO-VENEREOLOGICA
Year: 2017
Reference: Acta Derm Venereol. 2017 Nov 15;97(10):1241-1242. doi: 10.2340/00015555-2745.
Impact factor:
Publication type: Paper in international publication
Authors: Aparicio, Gloria; Esteves, Tiago C; Ferrer, Berta; Garcia-Patos, Vicente; Gonzalez-Lopez, Juanjo; Moure, Zaira; Romero, Dani; Sulleiro, Elena; Tortola, Teresa et al.
DOI: 10.2340/00015555-2745

ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment.

PMID: 28581514
Journal: ONCOGENE
Year: 2017
Reference: Oncogene. 2017 Oct 12;36(41):5695-5708. doi: 10.1038/onc.2017.160. Epub 2017 Jun 5.
Impact factor:
Publication type: Paper in international publication
Authors: Ceylan, I; Cortes, J; Costello, R; Ferrer, B; Fournet, G; Garcia-Patos, V; Hernandez-Losa, J; Martin, G; McGrail, K; Munoz, E et al.
DOI: 10.1038/onc.2017.160

Spiny hyperkeratosis (trichodysplasia spinulosa-like eruption): a cutaneous adverse effect of Hedgehog pathway inhibitors involving expression of p16.

PMID: 27510735
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2017
Reference: J Eur Acad Dermatol Venereol. 2017 Apr;31(4):e182-e184. doi: 10.1111/jdv.13907. Epub 2016 Aug 30.
Impact factor:
Publication type: Paper in international publication
Authors: Ferrer, B; Garcia-Patos, V; Hernandez-Losa, J; Lopez-Lerma, I; Zarzoso, I et al.
DOI: 10.1111/jdv.13907

Utility of Ultrasound in a Rapidly Growing Cutaneous Nodule in an Infant.

PMID: 27751521
Journal: JOURNAL OF PEDIATRICS
Year: 2017
Reference: J Pediatr. 2017 Jan;180:290-290.e1. doi: 10.1016/j.jpeds.2016.09.038. Epub 2016 Oct 14.
Impact factor:
Publication type: Paper in international publication
Authors: Aparicio, Gloria; Bassas, Patricia; Castany, Anna; Garcia-Patos, Vicente; Mollet, Jordi; Ubals, Maria et al.
DOI: 10.1016/j.jpeds.2016.09.038

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway.

PMID: 27057633
Journal: Oncotarget
Year: 2016
Reference: Oncotarget. 2016 May 10;7(19):28086-95. doi: 10.18632/oncotarget.8578.
Impact factor:
Publication type: Paper in international publication
Authors: Caratu, Ginevra; Cortes, Javier; Ferrer, Berta; Garcia-Patos, Vicente; Hernandez-Losa, Javier; Matito, Judit; Munoz, Eva; Perez-Alea, Mileidys; Recio, Juan A; Vivancos, Ana et al.
DOI: 10.18632/oncotarget.8578

Microarray study reveals a TGFbeta-Dependent mechanism of fibrosis in discoid lupus erythematosus.

PMID: 26972571
Journal: BRITISH JOURNAL OF DERMATOLOGY
Year: 2016
Reference: Br J Dermatol. 2016 Aug;175(2):302-13. doi: 10.1111/bjd.14539. Epub 2016 May 29.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, J; Ferrer, B; Gimenez-Barcons, M; Ordi-Ros, J; Sole, C et al.
DOI: 10.1111/bjd.14539

Epithelial-to-mesenchymal transition in penile squamous cell carcinoma.

PMID: 25063494
Journal: J UROLOGY
Year: 2015
Reference: J Urol. 2015 Feb;193(2):699-705. doi: 10.1016/j.juro.2014.07.083. Epub 2014 Jul 22.
Impact factor:
Publication type: Paper in international publication
Authors: Ferrandiz-Pulido, Carla; Garcia de Herreros, Antonio; Garcia-Patos, Vicenc; Gil, Inmaculada; Hernandez-Munoz, Inmaculada; Lloveras, Belen; Masferrer, Emili; Masferrer-Niubo, Magali; Pont, Antoni; Pujol, Ramon M et al.
DOI: 10.1016/j.juro.2014.07.083

Imiquimod and Photodynamic Therapy Are Useful in the Treatment of Porokeratosis in Children with Bone Marrow Transplantation.

PMID: 26223374
Journal: PEDIATR DERMATOL
Year: 2015
Reference: Pediatr Dermatol. 2015 Nov-Dec;32(6):e291-3. doi: 10.1111/pde.12654. Epub 2015 Jul 29.
Impact factor:
Publication type: Paper in international publication
Authors: Garcia-Patos, Vicente; Gilaberte, Yolanda; Gracia-Cazana, Tamara; Vera-Alvarez, Jesus et al.
DOI: 10.1111/pde.12654

Identification of somatic gene mutations in penile squamous cell carcinoma.

PMID: 26216163
Journal: GENE CHROMOSOME CANC
Year: 2015
Reference: Genes Chromosomes Cancer. 2015 Oct;54(10):629-37. doi: 10.1002/gcc.22274. Epub 2015 Jul 27.
Impact factor:
Publication type: Paper in international publication
Authors: Cajal, Y; de Torres, Ines; Ferrandiz-Pulido, Carla; Garcia-Patos, Vicente; Hernandez-Losa, Javier; Mares, Roso; Masferrer, Emili; Morote, Juan; Placer, Jose; Pujol, Ramon M et al.
DOI: 10.1002/gcc.22274

Long-term (1 year) efficacy of etanercept in moderate-to-severe psoriasis. Results of a multicentric observational study in Spain.

PMID: 26080687
Journal: EUR J DERMATOL
Year: 2015
Reference: Eur J Dermatol. 2015 Sep-Oct;25(5):410-7. doi: 10.1684/ejd.2015.2591.
Impact factor:
Publication type: Paper in international publication
Authors: Camacho, Francisco; Fernandez-Diaz, Maria Luisa; Garcia-Calvo, Carmen; Garcia-Patos, Vicente; Marquina, Amparo; Puig, Lluis et al.
DOI: 10.1684/ejd.2015.2591

Ribosomal proteins as novel players in tumorigenesis.

PMID: 24375388
Journal: CANCER AND METASTASIS REVIEWS
Year: 2014
Reference: Cancer Metastasis Rev. 2014 Mar;33(1):115-41. doi: 10.1007/s10555-013-9460-6.
Impact factor:
Publication type: Paper in international publication
Authors: de Las Heras-Rubio, A; Lleonart, M E; Paciucci, R; Perucho, L; Vilardell, J et al.
DOI: 10.1007/s10555-013-9460-6

A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation.

PMID: 25329316
Journal: PLoS Genetics
Year: 2014
Reference: PLoS Genet. 2014 Oct 16;10(10):e1004721. doi: 10.1371/journal.pgen.1004721. eCollection 2014 Oct.
Impact factor:
Publication type: Paper in international publication
Authors: Bastian, Boris; Bech-Serra, Joan Josep; Canals, Francesc; Cortes, Javier; Esteve-Puig, Rosaura; Ferrer, Berta; Flores, Juana Maria; Garcia-Patos, Vicenc; Gil, Rosa; Gonzalez-Sanchez, Elena et al.
DOI: 10.1371/journal.pgen.1004721

New approach to cancer therapy based on a molecularly defined cancer classification.

PMID: 24249308
Journal: CA-A CANCER JOURNAL FOR CLINICIANS
Year: 2014
Reference: CA Cancer J Clin. 2014 Jan-Feb;64(1):70-4. doi: 10.3322/caac.21211. Epub 2013 Nov 18.
Impact factor:
Publication type: Review in international publication
Authors: Calvo, Emiliano; Cortes, Javier; Perez-Garcia, Jose; Recio, Juan Angel; Seoane, Joan; Vivancos, Ana et al.
DOI: 10.3322/caac.21211

[Fever and skin lesions in a patient with chronic granulomatous disease.]

PMID: 24103241
Journal: ANALES DE PEDIATRIA
Year: 2014
Reference: An Pediatr (Barc). 2014 Feb;80(2):e50-1. doi: 10.1016/j.anpedi.2013.05.021. Epub 2013 Oct 6.
Impact factor:
Publication type: Letter whit IF
Authors: Ferrer Fabrega, B; Figueras Nadal, C; Garcia-Patos, V; Martin-Nalda, A; Rovira Castellvi, P et al.
DOI: 10.1016/j.anpedi.2013.05.021

Lkb1 loss promotes tumor progression of BRAF(V600E)-induced lung adenomas.

PMID: 23825589
Journal: PLoS One
Year: 2013
Reference: PLoS One. 2013 Jun 25;8(6):e66933. doi: 10.1371/journal.pone.0066933. Print 2013.
Impact factor:
Publication type: Paper in international publication
Authors: Barbacid, Mariano; Cortes, Javier; Flores, Juana Maria; Gonzalez-Sanchez, Elena; Hernandez-Losa, Javier; Mares, Roso; Martin-Caballero, Juan; Recio, Juan A et al.
DOI: 10.1371/journal.pone.0066933

Grovers disease in a peritoneal dialysis patient.

PMID: 23897199
Journal: NEFROLOGIA
Year: 2013
Reference: Nefrologia. 2013;33(4):608-9. doi: 10.3265/Nefrologia.pre2013.May.11220.
Impact factor:
Publication type: Letter whit IF
Authors: Agraz, Irene; Ferrer, Berta; Fort, Joan; Jatem, Elias; Ramos, Rosa; Semidei, M Eugenia et al.
DOI: 10.3265/Nefrologia.pre2013.May.11220

Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases.

PMID: 23928229
Journal: JOURNAL OF DERMATOLOGICAL SCIENCE
Year: 2013
Reference: J Dermatol Sci. 2013 Nov;72(2):93-102. doi: 10.1016/j.jdermsci.2013.07.001. Epub 2013 Jul 15.
Impact factor:
Publication type: Paper in international publication
Authors: Baro, Teresa; Casado, Beatriz; Costa, Irmgard; de Herreros, Antonio Garcia; Ferrandiz-Pulido, Carla; Gandarillas, Alberto; Garcia-Patos, Vicenc; Gimeno, Javier; Hernandez-Munoz, Inmaculada; Hernandez-Ruiz, M E et al.
DOI: 10.1016/j.jdermsci.2013.07.001

Aggressive Adult T Cell Leukemia/Lymphoma: The Tip of the Iceberg of the Hidden Human T Cell Lymphotropic Virus Type 1 Infection Burden in Nonendemic Countries.

PMID: 23228220
Journal: AIDS RESEARCH AND HUMAN RETROVIRUSES
Year: 2013
Reference: AIDS Res Hum Retroviruses. 2013 Apr;29(4):704-8. doi: 10.1089/AID.2012.0185. Epub 2012 Dec 26.
Impact factor:
Publication type: Paper in international publication
Authors: Caballero, Estrella; Garcia-Patos, Vicente; Lopez-Lerma, Ingrid; Palacio, Carlos et al.
DOI: 10.1089/AID.2012.0185

D2-40 immunohistochemical overexpression in cutaneous squamous cell carcinomas: A marker of metastatic risk.

PMID: 22521203
Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Year: 2012
Reference: J Am Acad Dermatol. 2012 Dec;67(6):1310-8. doi: 10.1016/j.jaad.2012.03.007. Epub 2012 Apr 20.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1016/j.jaad.2012.03.007

Penile Squamous Cell Carcinoma.

PMID: 22261674
Journal: Actas dermo-sifiliograficas
Year: 2012
Reference: Actas Dermosifiliogr. 2012 Jul-Aug;103(6):478-87. doi: 10.1016/j.ad.2011.08.008. Epub 2012 Jan 17.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; et al.
DOI: 10.1016/j.ad.2011.08.008

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations.

PMID: 21609436
Journal: Journal of Translational Medicine
Year: 2011
Reference: J Transl Med. 2011 May 24;9:76. doi: 10.1186/1479-5876-9-76.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/1479-5876-9-76

Tufted angioma associated with kasabach-merritt phenomenon: a therapeutic challenge.

PMID: 20814640
Journal: ACTA DERMATO-VENEREOLOGICA
Year: 2010
Reference: Acta Derm Venereol. 2010 Sep;90(5):536-8.
Impact factor:
Publication type: Letter or abstract
Authors: Ferrandiz-Pulido, Carla; Ferrer, Berta; Garcia-Patos, Vicente; Mollet, Jordi; Sabado, Constantino et al.
DOI: 10.2340/00015555-0848

Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth.

PMID: 20529342
Journal: BMC CANCER
Year: 2010
Reference: BMC Cancer. 2010 Jun 8;10:265. doi: 10.1186/1471-2407-10-265.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/1471-2407-10-265

The dual PI3K/mTOR inhibitor (PI-103) promotes immunosupression, in vivo tumor growth and increases survival of sorafenib treated melanoma cells.

PMID: 19810100
Journal: INTERNATIONAL JOURNAL OF CANCER
Year: 2010
Reference: Int J Cancer. 2010 Apr 1;126(7):1549-61.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1002/ijc.24926

Eccrine porocarcinoma presenting with scrotal lymphedema: a case report and review of systemic treatment.

PMID: 20089564
Journal: ANNALS OF ONCOLOGY
Year: 2010
Reference: Ann Oncol. 2010 Apr;21(4):907. Epub 2010 Jan 20.
Impact factor:
Publication type: Letter or abstract
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1093/annonc/mdp601

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The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

On World Cancer Research Day, we highlight the oncology research model of the Vall d'Hebron Campus that allows laboratory results to be transferred as quickly as possible to clinical practice.