About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Biomedical Research in Melanoma group is interested in skin cancer. We investigate the molecular causes for these diseases to design effective therapies against them. Our research is done in close proximity to patients, where our goal is to translate our discoveries as fast as possible to the clinic. To that end, we have a multidisciplinary group that associate dermatologists, oncologists, pathologists and basic-scientists that ask relevant clinical questions that need biological answers. Our workflow contemplates information obtained from patients (genetic information, clinical history, functional data…) that is translated into animal models (genetic modified mouse models, PDX…) and in vitro experiments to answer the formulated questions. These results are used to design novel therapeutic approaches, including drug development and preclinical studies that ultimately will be translated to patients.
The main lines of investigation are: • Molecular mechanisms involved in melanoma development and progression, • Targeting metabolism for melanoma treatment, • The mechanisms of resistance to immunotherapy.
PMID: 39036869 Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY Year: 2024 Reference: J Eur Acad Dermatol Venereol. 2024 Jul 22. doi: 10.1111/jdv.20250. Impact factor: Publication type: Paper in international publication Authors: Abril-Perez, Carlos; Baliu, Carola; Boada, Aram; Botella Estrada, Rafael; Castany, Anna; Deza, Gustavo; Ferrandiz-Pulido, Carla; Guerra-Amor, Alvaro; Jaka, Ane; Leal, Lorena et al. DOI: 10.1111/jdv.20250
PMID: 39040011 Journal: AMERICAN JOURNAL OF SURGICAL PATHOLOGY Year: 2024 Reference: Am J Surg Pathol. 2024 Jul 23. doi: 10.1097/PAS.0000000000002291. Impact factor: Publication type: Paper in international publication Authors: Ajami, Tarek; Algaba, Ferran; Corral, Juan Manuel; Darecka, Katarzyna; de Torres, Ines; Del Pino, Marta; Diez-Ahijado, Laia; Ferrandiz-Pulido, Carla; Garcia-Herrera, Adriana; Gaya, Josep Maria et al. DOI: 10.1097/PAS.0000000000002291
PMID: 39046711 Journal: JAMA Dermatology Year: 2024 Reference: JAMA Dermatol. 2024 Jul 24. doi: 10.1001/jamadermatol.2024.2242. Impact factor: Publication type: Paper in international publication Authors: Baum, Christian L; Bibee, Kristin P; Bordeaux, Jeremy S; Carr, David R; Carroll, Bryan T; Carter, Joi B; Carucci, John A; Cheraghlou, Shayan; Christensen, Sean R; Ferrandiz-Pulido, Carla et al. DOI: 10.1001/jamadermatol.2024.2242
PMID: 39115053 Journal: Molecular Oncology Year: 2024 Reference: Mol Oncol. 2024 Aug 8. doi: 10.1002/1878-0261.13715. Impact factor: Publication type: Paper in international publication Authors: Ding, Yuxin; Ferrer, Berta; Garcia-Patos, Vicente; Gonzalez-Sanchez, Elena; Granado-Martinez, Paula; Hernandez-Losa, Javier; Martin-Caballero, Juan; McGrail, Kimberley; Munoz-Couselo, Eva; Orsenigo, Roberto et al. DOI: 10.1002/1878-0261.13715
PMID: 37159995 Journal: ACTA BIOCHIMICA POLONICA Year: 2023 Reference: Acta Biochim Pol. 2023 May 9. doi: 10.18388/abp.2020_6588. Impact factor: Publication type: Paper in international publication Authors: Adamczak, Marcin; Chudek, Jerzy; Debska-Slizien, Alicja; Durlik, Magdalena; Ferrandiz-Pulido, Carla; Foroncewicz, Bartosz; Gellert, Ryszard; Krajewska, Magdalena; Kurnatowska, Ilona; Lizakowski, Slawomir et al. DOI: 10.18388/abp.2020_6588
PMID: 37088285 Journal: Actas dermo-sifiliograficas Year: 2023 Reference: Actas Dermosifiliogr. 2023 Apr 21:S0001-7310(23)00318-6. doi: 10.1016/j.ad.2023.04.022. Impact factor: Publication type: Paper in national publication Authors: Bea-Ardebol, S; Bonfill-Orti, M; Deza-Vargas, L G; Feal, C; Fernandez-de-Misa, R; Ferrandiz-Pulido, C; Florez, A; Galiano-Mejias, S; Hernandez-Hernandez, N; Jaka, A et al. DOI: 10.1016/j.ad.2023.04.022
PMID: 37830789 Journal: PEDIATRIC DERMATOLOGY Year: 2023 Reference: Pediatr Dermatol. 2023 Oct 13. doi: 10.1111/pde.15447. Impact factor: Publication type: Paper in international publication Authors: Aracil, Belen; Calvo-Montes, Jorge; Canada-Garcia, Javier E; Canton, Rafael; Casquero-Garcia, Veronica; Cercenado, Emilia; El Mammery, Achraf; Ferrandiz-Pulido, Carla; Garcia-Cobos, Silvia; Garcia-Patos, Vicente et al. DOI: 10.1111/pde.15447
PMID: 37828676 Journal: CURRENT MEDICINAL CHEMISTRY Year: 2023 Reference: Curr Med Chem. 2023 Oct 11. doi: 10.2174/0109298673268775231003111540. Impact factor: Publication type: Paper in international publication Authors: Andrade, Fernanda; Duran-Lara, Esteban F; Ferrandiz-Pulido, Carla; Garcia-Patos, Vicente; Gonzalez-Cruz, Carlos; Lobos G, Olga; Navarro, Alexandra; Navarro, Alexandra; Rafael, Diana; Repiso, Trinidad et al. DOI: 10.2174/0109298673268775231003111540
PMID: 33966586 Journal: LEUKEMIA & LYMPHOMA Year: 2021 Reference: Leuk Lymphoma. 2021 Sep;62(9):2130-2140. doi: 10.1080/10428194.2021.1901098. Epub 2021 May 8. Impact factor: Publication type: Paper in international publication Authors: Afonso-Martin, Juan Luis; Alonso-Alonso, Ruth; Borregon, Jennifer; Cereceda, Laura; Cerroni, Lorenzo; Cordoba, Raul; Estrach, Teresa; Ferrer, Berta; Garcia Toro, Enrique; Garcia, Candelaria et al. DOI: 10.1080/10428194.2021.1901098
PMID: 33197437 Journal: Actas dermo-sifiliograficas Year: 2021 Reference: Actas Dermosifiliogr. 2021 Mar;112(3):216-224. doi: 10.1016/j.ad.2020.11.005. Epub 2020 Nov 13. Impact factor: Publication type: Review in national publication Authors: Ferrandiz-Pulido, C; Garcia-Patos Briones, V; Gonzalez-Cruz, C et al. DOI: 10.1016/j.ad.2020.11.005
PMID: 32738832 Journal: Transplant Infectious Disease Year: 2021 Reference: Transpl Infect Dis. 2021 Feb;23(1):e13431. doi: 10.1111/tid.13431. Epub 2020 Aug 16. Impact factor: Publication type: Review in international publication Authors: Castells, Lluis; Ferrandiz-Pulido, Carla; Ferrer, Berta; Len, Oscar; Salcedo, Maria Teresa; Velasco, Marta et al. DOI: 10.1111/tid.13431
PMID: 32562197 Journal: Clinical & Translational Oncology Year: 2021 Reference: Clin Transl Oncol. 2021 Feb;23(2):311-317. doi: 10.1007/s12094-020-02420-9. Epub 2020 Jun 19. Impact factor: Publication type: Paper in international publication Authors: Bodet, D; Dienstmann, R; Garcia-Alvarez, A; Garcia-Patos, V; Hernando-Calvo, A; Munoz-Couselo, E; Ortiz, C; Recio, J A; Villacampa, G et al. DOI: 10.1007/s12094-020-02420-9
PMID: 32418618 Journal: Actas dermo-sifiliograficas Year: 2020 Reference: Actas Dermosifiliogr. 2020 Jun;111(5):357-363. doi: 10.1016/j.ad.2019.10.002. Epub 2020 May 14. Impact factor: Publication type: Paper in national publication Authors: Bassas Freixas, P; Cabezas-Calderon, V; Garcia-Patos Briones, V et al. DOI: 10.1016/j.ad.2019.10.002
PMID: 32389502 Journal: ANALES DE PEDIATRIA Year: 2020 Reference: An Pediatr (Barc). 2020 Jun;92(6):374-375. doi: 10.1016/j.anpedi.2020.04.013. Epub 2020 Apr 17. Impact factor: Publication type: Letter whit IF Authors: Espiau, Maria; Garcia-Patos, Vicenc; Lera-Carballo, Esther; Mercadal-Hally, Maria; Morey-Olive, Miriam et al. DOI: 10.1016/j.anpedi.2020.04.013
PMID: 30226477 Journal: Indian Journal of Dermatology Venereology & Leprology Year: 2020 Reference: Indian J Dermatol Venereol Leprol. 2020 Mar-Apr;86(2):215-217. doi: 10.4103/ijdvl.IJDVL_13_18. Impact factor: Publication type: Paper in international publication Authors: Bodet, Domingo; Garcia-Patos, Vicente; Gonzalez-Cruz, Carlos et al. DOI:
PMID: 32015486 Journal: ONCOGENE Year: 2020 Reference: Oncogene. 2020 Mar;39(13):2756-2771. doi: 10.1038/s41388-020-1184-9. Epub 2020 Feb 3. Impact factor: Publication type: Paper in international publication Authors: Borroto Escuela, Dasiel Oscar; Ceylan, Ismail; Costello, Regis; Di Stefano, Barbara; Fournet, Guy; Gonzalez, Elena; Iglesias I Felip, Carmela; Martin, Guillaume; Penarroche-Diaz, Reinier; Perez-Alea, Mileidys et al. DOI: 10.1038/s41388-020-1184-9
PMID: 30230044 Journal: MYCOSES Year: 2019 Reference: Mycoses. 2019 Feb;62(2):121-127. doi: 10.1111/myc.12853. Epub 2018 Oct 17. Impact factor: Publication type: Paper in international publication Authors: Aparicio, G; Ferrandiz-Pulido, C; Ferrer, B; Garcia-Patos, V; Gonzalez-Cruz, C; Juarez, C; Lopez-Lerma, I; Martin-Gomez, M T; Moreso, F; Repiso, T et al. DOI: 10.1111/myc.12853
PMID: 30130620 Journal: JOURNAL OF INVESTIGATIVE DERMATOLOGY Year: 2019 Reference: J Invest Dermatol. 2019 Jan;139(1):51-61. doi: 10.1016/j.jid.2018.07.026. Epub 2018 Aug 18. Impact factor: Publication type: Paper in international publication Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Ferrer, Berta; Moline, Teresa; Ordi-Ros, Josep; Sole, Cristina et al. DOI: 10.1016/j.jid.2018.07.026
PMID: 31153547 Journal: Actas dermo-sifiliograficas Year: 2019 Reference: Actas Dermosifiliogr. 2019 Oct;110(8):659-665. doi: 10.1016/j.ad.2019.02.003. Epub 2019 May 29. Impact factor: 0 Publication type: Paper in national publication Authors: Gonzalez-Cruz, C, Descalzo, M A, Arias-Santiago, S, Molina-Leyva, A, Gilaberte, Y, Fernandez-Crehuet, P, Viera-Ramirez, A, Fernandez-Penas, P, Taberner, R, Buendia-Eisman, A et al. DOI: 10.1016/j.ad.2019.02.003
PMID: 30850121 Journal: Actas dermo-sifiliograficas Year: 2019 Reference: Actas Dermosifiliogr. 2019 Sep;110(7):599-600. doi: 10.1016/j.ad.2018.01.018. Epub 2019 Mar 6. Impact factor: 0 Publication type: Paper in national publication Authors: Gonzalez-Cruz, C, Cabezas Calderon, V, Garcia-Patos Briones, V et al. DOI: 10.1016/j.ad.2018.01.018
PMID: 29429550 Journal: Actas dermo-sifiliograficas Year: 2018 Reference: Actas Dermosifiliogr. 2018 Apr;109(3):200-201. doi: 10.1016/j.ad.2017.12.002. Epub 2018 Feb 21. Impact factor: Publication type: Letter or abstract Authors: Ferrandiz-Pulido, C et al. DOI: 10.1016/j.ad.2017.12.002
PMID: 29394319 Journal: CARCINOGENESIS Year: 2018 Reference: Carcinogenesis. 2018 Mar 8;39(3):503-513. doi: 10.1093/carcin/bgy016. Impact factor: Publication type: Paper in international publication Authors: Andrades, Evelyn; Ferrandiz-Pulido, Carla; Garcia-Diez, Irene; Garcia-Patos, Vicenc; Gimeno, Javier; Gimeno, Ramon; Hernandez-Munoz, Inmaculada; Hernandez-Ruiz, Eugenia; Jaka, Ane; Masferrer, Emili et al. DOI: 10.1093/carcin/bgy016
PMID: 29149307 Journal: RHEUMATOLOGY Year: 2018 Reference: Rheumatology (Oxford). 2018 Feb 1;57(2):388-396. doi: 10.1093/rheumatology/kex413. Impact factor: Publication type: Paper in international publication Authors: Aparicio-Espanol, Gloria; Balada, Eva; Ferrer-Fabregas, Berta; Garcia-Patos, Vicente; Grau-Junyent, Josep M; Labrador-Horrillo, Moises; Martinez, Maria Angeles; Milisenda, Jose Cesar; Pinal-Fernandez, Iago; Selva-O'Callaghan, Albert et al. DOI: 10.1093/rheumatology/kex413
PMID: 29025692 Journal: Actas dermo-sifiliograficas Year: 2018 Reference: Actas Dermosifiliogr. 2018 Jan - Feb;109(1):83-86. doi: 10.1016/j.ad.2017.05.014. Epub 2017 Oct 10. Impact factor: Publication type: Paper in national publication Authors: Ferrandiz, C; Ferrandiz-Pulido, C; Lera-Imbuluzqueta, M; Plazas-Fernandez, M J et al. DOI: 10.1016/j.ad.2017.05.014
PMID: 26047065 Journal: J DERMATOL Year: 2015 Reference: J Dermatol. 2015 Dec;42(12):1172-5. doi: 10.1111/1346-8138.12967. Epub 2015 Jun 5. Impact factor: Publication type: Paper in international publication Authors: Ferrer, Berta; Garcia-Patos, Vicente; Gemigniani, Franco; Hernandez-Losa, Javier et al. DOI: 10.1111/1346-8138.12967
PMID: 26176264 Journal: AUTOPHAGY Year: 2015 Reference: Autophagy. 2015;11(9):1499-519. doi: 10.1080/15548627.2015.1063764. Impact factor: Publication type: Paper in international publication Authors: Artero-Castro, Ana; Castellvi, Josep; Feliciano, Andrea; Genestar, Monica; Leal, Jose A; LLeonart, Matilde E; Peg, Vicente; Perez-Alea, Mileidys; Ramon Y Cajal, Santiago et al. DOI: 10.1080/15548627.2015.1063764
PMID: 25485703 Journal: BIOCHEM BIOPH RES CO Year: 2015 Reference: Biochem Biophys Res Commun. 2015 Jan 2;456(1):489-93. doi: 10.1016/j.bbrc.2014.11.112. Epub 2014 Dec 6. Impact factor: Publication type: Paper in international publication Authors: Agnati, Luigi F; Belluardo, Natale; Borroto-Escuela, Dasiel O; Ciruela, Francisco; Fuxe, Kjell; Jimenez-Beristain, Antonio; Mudo, Giuseppa; Narvaez, Manuel; Perez-Alea, Mileidys; Tarakanov, Alexander O et al. DOI: 10.1016/j.bbrc.2014.11.112
PMID: 25957476 Journal: BIOCHEM BIOPH RES CO Year: 2015 Reference: Biochem Biophys Res Commun. 2015 Jul 31;463(3):180-6. doi: 10.1016/j.bbrc.2015.04.133. Epub 2015 May 6. Impact factor: Publication type: Paper in international publication Authors: Agnati, Luigi F; Belluardo, Natale; Borroto-Escuela, Dasiel O; Ciruela, Francisco; Fuxe, Kjell; Jimenez-Beristain, Antonio; Mudo, Giuseppa; Narvaez, Manuel; Perez-Alea, Mileidys; Tarakanov, Alexander O et al. DOI: 10.1016/j.bbrc.2015.04.133
PMID: 22863066 Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Year: 2013 Reference: J Am Acad Dermatol. 2013 Jan;68(1):73-82. doi: 10.1016/j.jaad.2012.05.029. Epub 2012 Aug 3. Impact factor: Publication type: Paper in international publication Authors: de Torres, Ines; Ferrandiz-Pulido, Carla; Garcia-Patos, Vicente; Hernandez-Losa, Javier; Lloveras, Belen; Masferrer, Emili; Mojal, Sergio; Morote, Juan; Pujol, Ramon M; Ramon Y Cajal, Santiago et al. DOI: 10.1016/j.jaad.2012.05.029
The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.
On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.
On World Cancer Research Day, we highlight the oncology research model of the Vall d'Hebron Campus that allows laboratory results to be transferred as quickly as possible to clinical practice.
