About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 37682330 Journal: PEDIATRIC RADIOLOGY Year: 2023 Reference: Pediatr Radiol. 2023 Sep 8. doi: 10.1007/s00247-023-05745-z. Impact factor: Publication type: Paper in international publication Authors: Adams, Madeleine; Bertolini, Patrizia; Bisogno, Gianni; Bouhamama, Amine; Caro-Dominguez, Pablo; Charon, Valerie; Chatziantoniou, Cyrano; Coma, Ana; Coma, Ana; Dandis, Rana et al. DOI: 10.1007/s00247-023-05745-z
PMID: 37723198 Journal: Communications Biology Year: 2023 Reference: Commun Biol. 2023 Sep 18;6(1):949. doi: 10.1038/s42003-023-05320-0. Impact factor: Publication type: Paper in international publication Authors: Berlanga, Pablo; Cairo, Stefano; Calvo, Julien; Casanova, Michela; Chastagner, Pascal; Cherkaoui, Sarah; Daudigeos-Dubus, Estelle; Delattre, Olivier; Dessen, Philippe; Droit, Robin et al. DOI: 10.1038/s42003-023-05320-0
PMID: 37769113 Journal: CANCER Year: 2023 Reference: Cancer. 2023 Sep 28. doi: 10.1002/cncr.35036. Impact factor: Publication type: Paper in international publication Authors: Arvis, Pierre; Brega, Nicoletta; Casanova, Michela; Demetri, George D; Dowlati, Afshin; Drilon, Alexander; Hong, David S; Keedy, Vicki L; Kummar, Shivaani; Lassen, Ulrik N et al. DOI: 10.1002/cncr.35036
PMID: 37795968 Journal: PEDIATRIC BLOOD & CANCER Year: 2023 Reference: Pediatr Blood Cancer. 2023 Oct 5:e30662. doi: 10.1002/pbc.30662. Impact factor: Publication type: Paper in international publication Authors: Daugherty, Claire; Gallardo, Eva; Gros, Luis; Gros, Luis; Hill, Christon; Janeway, Katherine A; Rizzari, Carmelo; Schwartz, Stefan; Schwartz, Stefan; Thomas, Emma et al. DOI: 10.1002/pbc.30662
PMID: 35292802 Journal: Cancer Discovery Year: 2022 Reference: Cancer Discov. 2022 May 2;12(5):1266-1281. doi: 10.1158/2159-8290.CD-21-1136. Impact factor: Publication type: Paper in international publication Authors: Abbou, Samuel; Adam de Beaumais, Tiphaine; Aerts, Isabelle; Andre, Nicolas; Berlanga, Pablo; Bernard, Virginie; Casanova, Michela; Chevassus, Cecile; Chicard, Mathieu; Corradini, Nadege et al. DOI: 10.1158/2159-8290.CD-21-1136
PMID: 35289066 Journal: JOURNAL OF THROMBOSIS AND HAEMOSTASIS Year: 2022 Reference: J Thromb Haemost. 2022 Jun;20(6):1390-1399. doi: 10.1111/jth.15699. Epub 2022 Mar 27. Impact factor: Publication type: Paper in international publication Authors: Benitez Munoz, Helga; Berrueco, Ruben; Dapena, Jose Luis; Garcia Abos, Miriam; Garcia-Morin, Marina; Gassiot, Susanna; Gonzalez, Berta; Lendinez, Francisco; Martinez Merino, Marta; Menarguez Lopez, Angela et al. DOI: 10.1111/jth.15699
PMID: 35278672 Journal: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Year: 2022 Reference: Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):602-613. doi: 10.1016/j.ijrobp.2022.03.003. Epub 2022 Mar 9. Impact factor: Publication type: Paper in international publication Authors: Ben-Arush, Myriam; Bolle, Stephanie; Borjesson, Anna; Burrieza, Gabriela Guillen; Cesen, Maja; Chargari, Cyrus; De Moerloose, Barbara; Defachelles, Anne-Sophie; Deutsch, Eric; Devalck, Christine et al. DOI: 10.1016/j.ijrobp.2022.03.003
PMID: 35241283 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Nov 11;159(9):411-419. doi: 10.1016/j.medcli.2022.01.009. Epub 2022 Feb 28. Impact factor: Publication type: Paper in national publication Authors: Alonso, Laura; Balas, Antonio; Benito, Ana; Bueno, David; Diaz de Heredia, Cristina; Fuster, Jose Luis; Galan-Gomez, Victor; Gonzalez-Vicent, Marta; Mestre, Carmen; Mozo, Yasmina et al. DOI: 10.1016/j.medcli.2022.01.009
PMID: 34077956 Journal: NEURO-ONCOLOGY Year: 2021 Reference: Neuro Oncol. 2021 Sep 1;23(9):1597-1611. doi: 10.1093/neuonc/noab136. Impact factor: Publication type: Paper in international publication Authors: Alderete, Daniel; Bovenschen, Niels; Burger, Peter; Capper, David; Cho, Jaeho; Cruz, Ofelia; de Rojas, Teresa; Dufour, Christelle; Eberhart, Charles; Figarella-Branger, Dominique et al. DOI: 10.1093/neuonc/noab136
PMID: 34076861 Journal: Clinical & Translational Oncology Year: 2021 Reference: Clin Transl Oncol. 2021 Dec;23(12):2489-2496. doi: 10.1007/s12094-021-02649-y. Epub 2021 Jun 2. Impact factor: Publication type: Paper in international publication Authors: Andres, M; Bautista, F; Canete, A; Castaneda Heredia, A; Cruz, O; Fernandez-Teijeiro, A; Gallego, S; Guerra-Garcia, P; Hladun Alvaro, R; Juan Ribelles, A et al. DOI: 10.1007/s12094-021-02649-y
PMID: 34025429 Journal: Frontiers in Pharmacology Year: 2021 Reference: Front Pharmacol. 2021 May 5;12:670945. doi: 10.3389/fphar.2021.670945. eCollection 2021. Impact factor: Publication type: Paper in international publication Authors: Agusti, Antonia; Alonso, Laura; Amaro-Hosey, Kristopher; Cereza, Gloria; Danes, Immaculada; Gros, Luis; Renedo, Berta; Vendrell, Lourdes; Vidal, Xavier et al. DOI: 10.3389/fphar.2021.670945
PMID: 34021390 Journal: EUROPEAN RADIOLOGY Year: 2021 Reference: Eur Radiol. 2021 Dec;31(12):8925-8936. doi: 10.1007/s00330-021-08026-1. Epub 2021 May 22. Impact factor: Publication type: Paper in international publication Authors: Beishuizen, Auke; Bruin, Marrie C A; de Keizer, Bart; de Lange, Charlotte; Enriquez, Goya; Granata, Claudio; Kwee, Thomas C; Littooij, Annemieke S; Miller, Elka; Nievelstein, Rutger A J et al. DOI: 10.1007/s00330-021-08026-1
PMID: 31586946 Journal: JOURNAL OF MEDICAL GENETICS Year: 2020 Reference: J Med Genet. 2020 Apr;57(4):258-268. doi: 10.1136/jmedgenet-2019-106249. Epub 2019 Oct 5. Impact factor: Publication type: Paper in international publication Authors: Ancliff, Phil; Antelo, Maria Luisa; Argiles, Bienvenida; Arrizabalaga, Beatriz; Aza-Carmona, Miriam; Badell, Isabel; Balmana, Judith; Banez, Fatima; Barragano, Marta; Bauser, Christopher et al. DOI: 10.1136/jmedgenet-2019-106249
PMID: 31090942 Journal: LARYNGOSCOPE Year: 2020 Reference: Laryngoscope. 2020 Apr;130(4):E243-E251. doi: 10.1002/lary.28062. Epub 2019 May 15. Impact factor: Publication type: Paper in international publication Authors: Bellia Munzon, Gaston; Bisogno, Gianni; Boglione, Mariano; Cecchetto, Giovanni; Couloigner, Vincent; Eliott, Martin J; Ferrari, Andrea; Guillen Burrieza, Gabriela; Irtan, Sabine; Khen Dunlop, Naziha et al. DOI: 10.1002/lary.28062
PMID: 32273586 Journal: BONE MARROW TRANSPLANTATION Year: 2020 Reference: Bone Marrow Transplant. 2020 Sep;55(9):1884. doi: 10.1038/s41409-020-0901-x. Impact factor: Publication type: Letter or abstract Authors: Afanasyev, Boris; Ansari, Marc; Badell, Isabel; Bosman, Paul; Cesaro, Simone; Chevalier, Patrice; Chybicka, Alicja; de Heredia, Cristina Diaz; de Latour, Regis Peffault; Dufour, Carlo et al. DOI: 10.1038/s41409-020-0901-x
PMID: 32268485 Journal: Cancers Year: 2020 Reference: Cancers (Basel). 2020 Apr 6;12(4). pii: cancers12040886. doi: 10.3390/cancers12040886. Impact factor: Publication type: Paper in international publication Authors: Barber, Marta; Castellvi, Josep; Gil-Moreno, Antonio; Majem, Blanca; Morote, Juan; Parrilla, Alfonso; Perez-Benavente, Asuncion; Sanchez, Jose Luis; Santamaria, Anna; Segura, Miguel F et al. DOI: 10.3390/cancers12040886
PMID: 30660643 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2019 Reference: J Allergy Clin Immunol. 2019 Jun;143(6):2238-2253. doi: 10.1016/j.jaci.2018.12.1010. Epub 2019 Jan 17. Impact factor: Publication type: Paper in international publication Authors: Al-Dhekri, Hasan; Al-Mousa, Hamoud; Al-Saud, Bandar; Albert, Michael H; Alonso, Laura; Aquino, Victor M; Arnaout, Rand; Balashov, Dmitry; Barlogis, Vincent; Bertrand, Yves et al. DOI: 10.1016/j.jaci.2018.12.1010
PMID: 31781490 Journal: Frontiers in Oncology Year: 2019 Reference: Front Oncol. 2019 Nov 6;9:1173. doi: 10.3389/fonc.2019.01173. eCollection 2019. Impact factor: 4.137 Publication type: Review in international publication Authors: Boloix, Ariadna, Masanas, Marc, Jimenez, Carlos, Antonelli, Roberta, Soriano, Aroa, Roma, Josep, Sanchez de Toledo, Josep, Gallego, Soledad, Segura, Miguel F et al. DOI: 10.3389/fonc.2019.01173
PMID: 30606492 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2019 Reference: Enferm Infecc Microbiol Clin. 2019 Mar;37(3):215-217. doi: 10.1016/j.eimc.2018.11.012. Epub 2018 Dec 31. Impact factor: 1.685 Publication type: Letter or abstract Authors: Barcelo, Maria Estrella, Navarro-Royo, Elisa, Melendo-Perez, Susana, Fenoy-Alejandre, Marina, Morey-Olive, Miriam, Soler-Palacin, Pere, Soler-Palacin, Pere, Melendo-Perez, Susana, Mendoza-Palomar, Natalia, Fernandez-Polo, Aurora et al. DOI: 10.1016/j.eimc.2018.11.012
PMID: 30586230 Journal: AMERICAN JOURNAL OF TRANSPLANTATION Year: 2019 Reference: Am J Transplant. 2019 Jun;19(6):1798-1805. doi: 10.1111/ajt.15240. Epub 2019 Jan 25. Impact factor: 7.163 Publication type: Paper in international publication Authors: Bader, P, Dalissier, A, Ifversen, M, Schulz, A, Gennery, A, Burkhardt, B, Badell Serra, I, Diaz-de-Heredia, C, Lanino, E, Lankester, A C et al. DOI: 10.1111/ajt.15240
PMID: 29797665 Journal: CANCER Year: 2018 Reference: Cancer. 2018 Aug 1;124(15):3201-3209. doi: 10.1002/cncr.31553. Epub 2018 May 24. Impact factor: 6.537 Publication type: Paper in international publication Authors: Ferman, Sima, Gallego, Soledad, Zanetti, Ilaria, Orbach, Daniel, Ranchere, Dominique, Shipley, Janet, Zin, Angelica, Bergeron, Christophe, de Salvo, Gian Luca, Chisholm, Julia et al. DOI: 10.1002/cncr.31553
PMID: 29781567 Journal: PEDIATRIC BLOOD & CANCER Year: 2018 Reference: Pediatr Blood Cancer. 2018 Sep;65(9):e27096. doi: 10.1002/pbc.27096. Epub 2018 May 21. Impact factor: 2.646 Publication type: Paper in international publication Authors: Minard-Colin, Veronique, Walterhouse, David, Bisogno, Gianni, Martelli, Helene, Anderson, James, Rodeberg, David A, Ferrari, Andrea, Jenney, Meriel, Wolden, Suzanne, Arndt, Carola et al. DOI: 10.1002/pbc.27096
PMID: 29776868 Journal: Journal of Pediatric Urology Year: 2018 Reference: J Pediatr Urol. 2018 Oct;14(5):366-373. doi: 10.1016/j.jpurol.2018.03.018. Epub 2018 Apr 20. Impact factor: 1.935 Publication type: Review in national publication Authors: Gander, Romy, Asensio, Marino, Guillen, Gabriela, Royo, Gloria Fatou, Bolanos, Andrea, Perez, Mercedes, Diaz-De-Heredia, Cristina, Benitez, Maribel, Lopez, Manuel et al. DOI: 10.1016/j.jpurol.2018.03.018
PMID: 29700278 Journal: EXPERIMENTAL AND MOLECULAR MEDICINE Year: 2018 Reference: Exp Mol Med. 2018 Apr 27;50(4):51. doi: 10.1038/s12276-018-0077-2. Impact factor: 5.584 Publication type: Review in international publication Authors: Jimenez, Carlos, Jubierre, Luz, Sabado, Constantino, Gros, Luis, Llort, Anna, Hladun, Raquel, Roma, Josep, Toledo, Josep Sanchez de, Gallego, Soledad, Segura, Miguel F et al. DOI: 10.1038/s12276-018-0077-2
PMID: 27882658 Journal: PEDIATRIC BLOOD & CANCER Year: 2017 Reference: Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26348. Epub 2016 Nov 24. Impact factor: 2.634 Publication type: Paper in international publication Authors: Ferrari, Andrea, Trama, Annalisa, De Paoli, Angela, Merks, Johannes H M, Jenney, Meriel, Orbach, Daniel, Chisholm, Julia C, Gallego, Soledad, Glosli, Heidi, De Salvo, Gian Luca et al. DOI: 10.1002/pbc.26348
PMID: 27888015 Journal: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION Year: 2017 Reference: Biol Blood Marrow Transplant. 2017 Mar;23(3):491-497. doi: 10.1016/j.bbmt.2016.11.014. Epub 2016 Nov 22. Impact factor: 3.98 Publication type: Paper in international publication Authors: Castillo, Nerea, Garcia-Cadenas, Irene, Barba, Pere, Canals, Carme, Diaz-Heredia, Cristina, Martino, Rodrigo, Ferra, Christelle, Badell, Isabel, Elorza, Izaskun, Sierra, Jorge et al. DOI: 10.1016/j.bbmt.2016.11.014
PMID: 27718156 Journal: Clinical & Translational Oncology Year: 2017 Reference: Clin Transl Oncol. 2017 Jan;19(1):44-50. doi: 10.1007/s12094-016-1557-2. Epub 2016 Oct 7. Impact factor: 2.075 Publication type: Paper in international publication Authors: Zarzosa, P, Navarro, N, Giralt, I, Molist, C, Almazan-Moga, A, Vidal, I, Soriano, A, Segura, M F, Hladun, R, Villanueva, A et al. DOI: 10.1007/s12094-016-1557-2
PMID: 27459057 Journal: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK Year: 2017 Reference: Head Neck. 2017 Jan;39(1):24-31. doi: 10.1002/hed.24547. Epub 2016 Jul 26. Impact factor: 2.76 Publication type: Paper in international publication Authors: Mosseri, Veronique, Gallego, Soledad, Kelsey, Anna, Devalck, Christine, Brenann, Bernadette, van Noesel, Max M, Bergeron, Christophe, Merks, Johannes H M, Rechnitzer, Catherine, Jenney, Meriel et al. DOI: 10.1002/hed.24547
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
