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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Xavier Montalban Gairín

Xavier Montalban Gairín

Head of group
Clinical Neuroimmunology
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Jaume Sastre Garriga

Jaume Sastre Garriga

Main researcher
Clinical Neuroimmunology
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Jordi Rio Izquierdo

Jordi Rio Izquierdo

Senior researcher
Clinical Neuroimmunology
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Manuel Comabella Lopez

Manuel Comabella Lopez

Main researcher
Clinical Neuroimmunology
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Mar Tintore Subirana

Mar Tintore Subirana

Main researcher
Clinical Neuroimmunology
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Nicolás Miguel Fissolo

Nicolás Miguel Fissolo

Main researcher
Clinical Neuroimmunology
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Xavier Montalban Gairín

Xavier Montalban Gairín

Head of group
Clinical Neuroimmunology
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Jaume Sastre Garriga

Jaume Sastre Garriga

Main researcher
Clinical Neuroimmunology
Read more
Jordi Rio Izquierdo

Jordi Rio Izquierdo

Senior researcher
Clinical Neuroimmunology
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Manuel Comabella Lopez

Manuel Comabella Lopez

Main researcher
Clinical Neuroimmunology
Read more
Mar Tintore Subirana

Mar Tintore Subirana

Main researcher
Clinical Neuroimmunology
Read more
Nicolás Miguel Fissolo

Nicolás Miguel Fissolo

Main researcher
Clinical Neuroimmunology
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Research lines

Biomarkers of susceptibility, diagnosis and prognosis in MS (IV)

Study of humoral responses against Epstein-Barr virus as a long-term prognostic factor in patients with MS.


Characterization of the immunological profiles associated with the different MS phenotypes.


Study of extracellular vesicles derived from CNS cells as prognostic biomarkers in patients with MS.


IP: Manuel Comabella Lopez

Multiple sclerosis and Gender

We focused on studying the impact of sexual hormones and the different reproductive stages of a woman's life on multiple sclerosis. As part of this project we have achieved the following publications:


1 - Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis.

2 - Oral contraceptives do not modify the risk of a second attack and disability accrual in a prospective cohort of women with a clinically isolated syndrome and early multiple sclerosis.

3 - Menopause does not modify disability trajectories in a longitudinal cohort of women with clinically isolated syndrome and multiple sclerosis followed from disease onset.

4 - Menopause and multiple sclerosis: Influence on prognosis and role of disease-modifying drugs and hormonal replacement therapy.

IP: Mar Tintore Subirana, Luciana Midaglia Fernandez

Study of the pathogenesis of MS and search for new targets and/or therapeutic approaches (II)

Delve in the characterization of therapeutic targets identified by the group i.e. chitinase 3-like 1 and the NLRP3 inflammasome, for the development of new treatments in patients with MS.


Development of new humanized preclinical models of MS to investigate primary glial pathology, as well as the neuroprotective potential of new therapeutic agents: (i) generation of human glial chimeric mice with experimental autoimmune encephalomyelitis; (ii) transplantation of oligodendrocytes derived from MS patients into demyelinated human brain-slice cultures.

IP: Manuel Comabella Lopez

Projects

Characterization of chitinase 3 like (CHI3L1) effect on neurons: Towards developing CHI3L1 inhibitors to prevent disease progression in MS

IP: Manuel Comabella Lopez
Collaborators: -
Funding agency: Asociación Esclerosis Múltiple España
Funding: 50000
Reference: EME/PROJECTE/2024/COMABELLA
Duration: 30/09/2024 - 30/09/2025

Senolytic Therapy: A novel approach for immune rejuvenation in aged and progressive multiple sclerosis

IP: Carmen Espejo Ruiz
Collaborators: -
Funding agency: Asociación Esclerosis Múltiple España
Funding: 25000
Reference: EME/PROJECTE/2024/ESPEJO
Duration: 30/09/2024 - 30/09/2025

BIOBANCOS Y BIOMODELOS

IP: Isabel Novoa Garcia
Collaborators: Joaquim Vives Armengol, Anna Duarri Piqué, Eva Colas Ortega, Oriol Bestard Matamoros, Marta Rosal Fontana, Carmen Espejo Ruiz, Marielle Esteves Coelho, Juan Jose Gonzalez Lopez, Sheyla Pascual Martín, Alejandro Tomasello Weitz, Shirley Guzmán Avilés
Funding agency: Instituto de Salud Carlos III
Funding: 137460
Reference: PT23/00040
Duration: 01/01/2024 - 31/12/2026

A new in vitro human model to study MOGAD physiopathology: the MOGAXON project Background

IP: Alvaro Cobo Calvo
Collaborators: -
Funding agency: The Sumaira Foundation
Funding: 25000
Reference: MOGAXON_SUMAIRA/COBO
Duration: 06/03/2024 - 31/03/2026

Publications

Complement Activation Profiles Predict Clinical Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

PMID: 39661937
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2025
Reference: Neurol Neuroimmunol Neuroinflamm. 2025 Jan;12(1):e200340. doi: 10.1212/NXI.0000000000200340. Epub 2024 Dec 11.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez Bravo, Gary; Armangue, Thais; Arrambide, Georgina; Blanco, Yolanda; Bollo, Luca; Castillo, Mireia; Cobo-Calvo, Alvaro; Comabella, Manuel; Dinoto, Alessandro; Espejo, Carmen et al.
DOI: 10.1212/NXI.0000000000200340

Association of the Cervical Canal Area With Disability and Progression in People With Multiple Sclerosis.

PMID: 39666921
Journal: NEUROLOGY
Year: 2025
Reference: Neurology. 2025 Jan 14;104(1):e210136. doi: 10.1212/WNL.0000000000210136. Epub 2024 Dec 12.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Auger, Cristina; Barkhof, Frederik; Bellenberg, Barbara; Bisecco, Alvino; Braga, Nathane; Carbonell-Mirabent, Pere; Ciccarelli, Olga; De Angelis, Floriana; Eisele, Philipp et al.
DOI: 10.1212/WNL.0000000000210136

Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

PMID: 39752619
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2025
Reference: Neurol Neuroimmunol Neuroinflamm. 2025 Mar;12(2):e200362. doi: 10.1212/NXI.0000000000200362. Epub 2025 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Alcala, Carmen; Alonso, Ana; Alvarez Bravo, Gary; Arrambide, Georgina; Audoin, Bertrand; Auger, Cristina; Ayrignac, Xavier; Benyahya, Lakhdar; Bernard-Valnet, Raphael; Bourre, Bertrand et al.
DOI: 10.1212/NXI.0000000000200362

A data-driven model of disability progression in progressive multiple sclerosis.

PMID: 39777254
Journal:
Year: 2025
Reference: Brain Commun. 2024 Dec 3;7(1):fcae434. doi: 10.1093/braincomms/fcae434. eCollection 2025.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Bovis, Francesca; Cree, Bruce A C; Garbarino, Sara; Lorenzi, Marco; Pardini, Matteo; Piana, Michele; Sormani, Maria Pia; Tur, Carmen; Uccelli, Antonio et al.
DOI: 10.1093/braincomms/fcae434

Optic nerve topography in multiple sclerosis diagnostic criteria: Existing knowledge and future directions.

PMID: 38243584
Journal: Multiple Sclerosis Journal
Year: 2024
Reference: Mult Scler. 2024 Jan 19:13524585231225848. doi: 10.1177/13524585231225848.
Impact factor:
Publication type: Paper in international publication
Authors: Montalban, Xavier; Rovira, Alex; Sastre-Garriga, Jaume; Tintore, Mar; Vidal-Jordana, Angela et al.
DOI: 10.1177/13524585231225848

Radial Versus Femoral Access for Mechanical Thrombectomy in Stroke Patients: A Non-Inferiority Randomized Clinical Trial.

PMID: 38299334
Journal: STROKE
Year: 2024
Reference: Stroke. 2024 Feb 1. doi: 10.1161/STROKEAHA.124.046360.
Impact factor:
Publication type: Paper in international publication
Authors: Carmona, Tomas; De Dios Lascuevas, Marta; Diana, Francesco; Garcia-Tornel, Alvaro; Gramegna, Laura Ludovica; Hernandez, David; Juega, Jesus; Molina, Carlos A; Muchada, Marian; Olive Gadea, Marta et al.
DOI: 10.1161/STROKEAHA.124.046360

Optic chiasm manual and automated measurements in sub-acute optic neuritis with OCT and MRI correlations.

PMID: 38290202
Journal: EUROPEAN JOURNAL OF RADIOLOGY
Year: 2024
Reference: Eur J Radiol. 2024 Jan 26;172:111332. doi: 10.1016/j.ejrad.2024.111332.
Impact factor:
Publication type: Paper in international publication
Authors: Alberich, Manel; Appriou, Candice; Braga, Nathane; Cabello, Sergio; Mongay-Ochoa, Neus; Montalban, Xavier; Pareto, Deborah; Rodriguez, Breogan; Rovira, Alex; Sastre-Garriga, Jaume et al.
DOI: 10.1016/j.ejrad.2024.111332

Effect of Evobrutinib on Slowly Expanding Lesion Volume in Relapsing Multiple Sclerosis: A Post Hoc Analysis of a Phase 2 Trial.

PMID: 38335474
Journal: NEUROLOGY
Year: 2024
Reference: Neurology. 2024 Mar 12;102(5):e208058. doi: 10.1212/WNL.0000000000208058. Epub 2024 Feb 9.
Impact factor:
Publication type: Paper in international publication
Authors: Arnold, Douglas L; Elliott, Colm; Hyvert, Yann; Martin, Emily C; Montalban, Xavier; Tomic, Davorka et al.
DOI: 10.1212/WNL.0000000000208058

[Esclerosis multiple. Lactancia. Lactante. Planificacion familiar. Posparto. Tratamiento modificador de la enfermedad.].

PMID: 36544373
Journal: REVISTA DE NEUROLOGIA
Year: 2023
Reference: Rev Neurol. 2023 Jan 1;76(1):21-30. doi: 10.33588/rn.7601.2022404.
Impact factor:
Publication type: Review in national publication
Authors: Agusti, A; Bosch, M; Carreras, E; Castillo, F; Horno, R; Midaglia, L; Montalban, X; Sanchez-Velasco, S; Serrano, B; Tintore, M et al.
DOI: 10.33588/rn.7601.2022404

Spinal cord lesions and brain grey matter atrophy independently predict clinical worsening in definite multiple sclerosis: a 5-year, multicentre study.

PMID: 36171105
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Jan;94(1):10-18. doi: 10.1136/jnnp-2022-329854. Epub 2022 Sep 28.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, Frederik; Barkhof, Frederik; Bellenberg, Barbara; Bisecco, Alvino; Ciccarelli, Olga; Ciccarelli, Olga; Eisele, Philipp; Enzinger, Christian; Filippi, Massimo; Filippi, Massimo et al.
DOI: 10.1136/jnnp-2022-329854

Characterisation of the safety profile of evobrutinib in over 1000 patients from phase II clinical trials in multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus: an integrated safety analysis.

PMID: 36418156
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Jan;94(1):1-9. doi: 10.1136/jnnp-2022-328799. Epub 2022 Nov 23.
Impact factor:
Publication type: Paper in international publication
Authors: Genovese, Mark C; Guehring, Hans; Kao, Amy H; Le Bolay, Claire; Montalban, Xavier; Parsons-Rich, Dana; Tomic, Davorka; Wallace, Daniel et al.
DOI: 10.1136/jnnp-2022-328799

Multiple sclerosis progression: time for a new mechanism-driven framework.

PMID: 36410373
Journal: LANCET NEUROLOGY
Year: 2023
Reference: Lancet Neurol. 2023 Jan;22(1):78-88. doi: 10.1016/S1474-4422(22)00289-7. Epub 2022 Nov 18.
Impact factor:
Publication type: Review in international publication
Authors: 2022/11/22 06:00; Banwell, Brenda; Barkhof, Frederik; Chataway, Jeremy; Chitnis, Tanuja; Coetzee, Timothy; Cohen, Jeffrey A; Comi, Giancarlo; Correale, Jorge; Derfuss, Tobias et al.
DOI: 10.1016/S1474-4422(22)00289-7

Biopsychosocial Response to the COVID-19 Lockdown in People with Major Depressive Disorder and Multiple Sclerosis.

PMID: 36498739
Journal: Journal of Clinical Medicine
Year: 2022
Reference: J Clin Med. 2022 Dec 1;11(23):7163. doi: 10.3390/jcm11237163.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilo, Jordi; Annas, Peter; Arranz, Belen; Bailon, Raquel; Buron, Mathias Due; Comi, Giancarlo; Cummins, Nicholas; Dalla Costa, Gloria; Difrancesco, Sonia; Dineley, Judith et al.
DOI: 10.3390/jcm11237163

Peripheral myeloid-derived suppressor cells are good biomarkers of the efficacy of fingolimod in multiple sclerosis.

PMID: 36403026
Journal: Journal of Neuroinflammation
Year: 2022
Reference: J Neuroinflammation. 2022 Nov 19;19(1):277. doi: 10.1186/s12974-022-02635-3.
Impact factor:
Publication type: Paper in international publication
Authors: Cabanas-Cotillas, Maria; Calahorra, Leticia; Camacho-Toledano, Celia; Castillo-Trivino, Tamara; Clemente, Diego; Comabella, Manuel; Costa-Frossard, Lucienne; Garcia-Arocha, Jennifer; Garcia-Dominguez, Jose Manuel; Machin-Diaz, Isabel et al.
DOI: 10.1186/s12974-022-02635-3

Preferences Toward Attributes of Disease-Modifying Therapies: The Role of Nurses in Multiple Sclerosis Care.

PMID: 35700983
Journal: JOURNAL OF NEUROSCIENCE NURSING
Year: 2022
Reference: J Neurosci Nurs. 2022 Oct 1;54(5):220-225. doi: 10.1097/JNN.0000000000000661. Epub 2022 Jun 13.
Impact factor:
Publication type: Paper in international publication
Authors: Azanza-Munarriz, Cristina; Becerril-Rios, Noelia; Bueno-Gil, Guillermo; Del Rio-Munoz, Beatriz; Goicochea-Briceno, Haydee; Horno, Rosalia; Lendinez-Mesa, Alejandro; Maurino, Jorge; Medrano, Nicolas; Sanchez-Franco, Cesar et al.
DOI: 10.1097/JNN.0000000000000661

The utility of wearable devices in assessing ambulatory impairments of people with multiple sclerosis in free-living conditions.

PMID: 36371974
Journal: Computer Methods and Programs in Biomedicine
Year: 2022
Reference: Comput Methods Programs Biomed. 2022 Dec;227:107204. doi: 10.1016/j.cmpb.2022.107204. Epub 2022 Oct 31.
Impact factor:
Publication type: Paper in international publication
Authors: Bailon, Raquel; Comi, Giancarlo; Conde, Pauline; Cummins, Nicholas; Dalla Costa, Gloria; Dobson, Richard Jb; Folarin, Amos A; Guerrero, Ana Isabel; Hotopf, Matthew; Laiou, Petroula et al.
DOI: 10.1016/j.cmpb.2022.107204

Innovation in resident education - Description of the Neurology International Residents Videoconference and Exchange (NIRVE) program.

PMID: 33223147
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2021
Reference: J Neurol Sci. 2021 Jan 15;420:117222. doi: 10.1016/j.jns.2020.117222. Epub 2020 Nov 8.
Impact factor:
Publication type: Editorail in international publication
Authors: Chan, David K; Freedman, Morris; Gros, Priti; Kinach, Mark; Montalban, Xavier; Rotstein, Dalia; Sasikumar, Sanskriti et al.
DOI: 10.1016/j.jns.2020.117222

Development and evaluation of a manual segmentation protocol for deep grey matter in multiple sclerosis: Towards accelerated semi-automated references.

PMID: 33882422
Journal: NeuroImage-Clinical
Year: 2021
Reference: Neuroimage Clin. 2021;30:102659. doi: 10.1016/j.nicl.2021.102659. Epub 2021 Apr 6.
Impact factor:
Publication type: Paper in international publication
Authors: Amann, Michael; Barkhof, Frederik; Bartel, Fabian; Burggraaff, Jessica; de Sitter, Alexandra; Enzinger, Christian; Filippi, Massimo; Frederiksen, Jette; Gallo, Antonio; Gasperini, Claudio et al.
DOI: 10.1016/j.nicl.2021.102659

Women's Health in Multiple Sclerosis: A Scoping Review.

PMID: 35173669
Journal: Frontiers in Neurology
Year: 2021
Reference: Front Neurol. 2022 Jan 31;12:812147. doi: 10.3389/fneur.2021.812147. eCollection 2021.
Impact factor:
Publication type: Review in international publication
Authors: Amato, Maria Pia; Cohen, Jeffrey A; Harnegie, Mary Pat; Hellwig, Kerstin; Marrie, Ruth Ann; Ng, Huah Shin; O'Mahony, Julia; Ross, Lindsay; Tintore, Mar; Vukusic, Sandra et al.
DOI: 10.3389/fneur.2021.812147

Genomic Multiple Sclerosis Risk Variants Modulate the Expression of the ANKRD55-IL6ST Gene Region in Immature Dendritic Cells.

PMID: 35111166
Journal: Frontiers in Immunology
Year: 2021
Reference: Front Immunol. 2022 Jan 17;12:816930. doi: 10.3389/fimmu.2021.816930. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Aldekoa, Ane; Alloza, Iraide; Alvarez de Arcaya, Amaya; Antiguedad, Alfredo; Boyero, Sabas; Comabella, Manuel; Diez Garcia, Javier; Lindskog, Cecilia; Malhotra, Sunny; Mena, Jorge et al.
DOI: 10.3389/fimmu.2021.816930

Multiple sclerosis in the Middle East and North Africa region.

PMID: 35145729
Journal: Multiple sclerosis journal - experimental, transla
Year: 2020
Reference: Mult Scler J Exp Transl Clin. 2020 Jan 9;6(1):2055217319895540. doi: 10.1177/2055217319895540. eCollection 2020 Jan-Mar.
Impact factor:
Publication type: Editorail in international publication
Authors: Khoury, Samia J; Tintore, Mar et al.
DOI: 10.1177/2055217319895540

Radiologically Isolated Syndrome: 10-Year Risk Estimate of a Clinical Event.

PMID: 32500558
Journal: ANNALS OF NEUROLOGY
Year: 2020
Reference: Ann Neurol. 2020 Aug;88(2):407-417. doi: 10.1002/ana.25799. Epub 2020 Jun 29.
Impact factor:
Publication type: Paper in international publication
Authors: Amato, Maria Pia; Azevedo, Christina; Bensa, Caroline; Berger, Eric; Brochet, Bruno; Ciron, Jonathan; Cohen, Mikael; de Seze, Jerome; deStefano, Nicola; Inglese, Matilde et al.
DOI: 10.1002/ana.25799

Falls in People with Multiple Sclerosis: Risk Identification, Intervention, and Future Directions.

PMID: 33424479
Journal: International journal of MS care
Year: 2020
Reference: Int J MS Care. 2020 Nov-Dec;22(6):247-255. doi: 10.7224/1537-2073.2020-014. Epub 2020 Sep 14.
Impact factor:
Publication type: Paper in international publication
Authors: Comber, Laura; Coote, Susan; Gunn, Hilary; Kalron, Alon; Quinn, Gillian; Santoyo-Medina, Carme et al.
DOI: 10.7224/1537-2073.2020-014

Assessing life balance of European people with multiple sclerosis: A multicenter clinimetric study within the RIMS network.

PMID: 31915118
Journal: Multiple Sclerosis and Related Disorders
Year: 2020
Reference: Multiple Sclerosis and Related Disorders. 2020 Apr;39:101879.
Impact factor:
Publication type: Paper in international publication
Authors: Beckerman, Heleen; Duportail, Marijke; Eijssen, Isaline; Ferdinand, Sofie; Fillo, Núria; Jansa, Jelka; Kerkhofs, Lore; Kos, Daphne; Matuska, Kathleen; Schouteden, Sofie et al.
DOI: 10.1016/j.msard.2019.101879

Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.

PMID: 31043474
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 May 28;92(22):e2538-e2549. doi: 10.1212/WNL.0000000000007572. Epub 2019 May 1.
Impact factor:
Publication type: Paper in international publication
Authors: Aaen, Gregory; Al-Roughani, Raed; Albino da Paz, Jose; Alvarez, Veronica Gonzalez; Amato, Maria-Pia; Anagnostouli, Maria; Anlar, Banu; Armangue, Thais; Arrambide, Georgina; Banwell, Brenda et al.
DOI: 10.1212/WNL.0000000000007572

Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk.

PMID: 31251915
Journal: CELL
Year: 2019
Reference: Cell. 2019 Jun 27;178(1):262. doi: 10.1016/j.cell.2019.06.016.
Impact factor:
Publication type: Letter or abstract
Authors: Agliardi, Cristina; Alfredsson, Lars; Andlauer, Till F M; Ban, Maria; Baranzini, Sergio E; Barcellos, Lisa F; Barizzone, Nadia; Bayas, Antonios; Beecham, Ashley H; Bergh, Florian Then et al.
DOI: 10.1016/j.cell.2019.06.016

Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial.

PMID: 31285147
Journal: LANCET NEUROLOGY
Year: 2019
Reference: Lancet Neurol. 2019 Sep;18(9):845-856. doi: 10.1016/S1474-4422(19)30137-1. Epub 2019 Jul 5.
Impact factor:
Publication type: Paper in international publication
Authors: Aguera Morales, Eduardo; Al Khedr, Abdullatif; Ampapa, Radek; Arnold, Douglas L; Arroyo, Rafael; Belkin, Martin; Bonek, Robert; Boyko, Alexey; Cadavid, Diego; Calabresi, Peter A et al.
DOI: 10.1016/S1474-4422(19)30137-1

Effectiveness of delayed-release dimethyl fumarate on patient-reported outcomes and clinical measures in patients with relapsing-remitting multiple sclerosis in a real-world clinical setting: PROTEC.

PMID: 31832225
Journal: Multiple sclerosis journal - experimental, transla
Year: 2019
Reference: Mult Scler J Exp Transl Clin. 2019 Dec 2;5(4):2055217319887191. doi: 10.1177/2055217319887191. eCollection 2019 Oct-Dec.
Impact factor:
Publication type: Paper in international publication
Authors: Berger, T; Brambilla, L; Bretagne, A; Brochet, B; Giacomini, P S; Montalban, X; Su, R; Vasco Salgado, A et al.
DOI: 10.1177/2055217319887191

Epidemiology of NMOSD in Catalonia: Influence of the new 2015 criteria in incidence and prevalence estimates.

PMID: 28984163
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Dec;24(14):1843-1851. doi: 10.1177/1352458517735191. Epub 2017 Oct 6.
Impact factor:
Publication type: Paper in international publication
Authors: Aldea, Marta; Armangue, Thais; Arrambide, Georgina; Blanco, Yolanda; Brieva, Luis; Cano, Antonio; Escartin, Antonio; Escudero, Domingo; Graus, Francesc; Gubieras, Laura et al.
DOI: 10.1177/1352458517735191

Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop.

PMID: 28671487
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Apr 1;24(5):590-603. doi: 10.1177/1352458516686847.
Impact factor:
Publication type: Paper in international publication
Authors: Alfredsson, Lars; Aloisi, Francesca; Amato, Maria Pia; Amato, Maria Pia; Ascherio, Alberto; Baldin, Elisa; Bjornevik, Kjetil; Comabella, Manuel; Correale, Jorge; Cortese, Marianna et al.
DOI: 10.1177/1352458516686847

Response to the commentary of Yates RL and DeLuca GC on the study: HLA-DRB1*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis.

PMID: 29409599
Journal: Multiple Sclerosis and Related Disorders
Year: 2018
Reference: Mult Scler Relat Disord. 2018 Jan;19:168-170. doi: 10.1016/j.msard.2016.08.006. Epub 2016 Aug 12.
Impact factor:
Publication type: Review in international publication
Authors: Chard, Declan T; Hardy, John; Houlden, Henry; Liu, Zheng; Miller, David H; Mok, Kin Y; Muhlert, Nils; Pardini, Matteo; Samson, Rebecca S; Sethi, Varun et al.
DOI: 10.1016/j.msard.2016.08.006

Intra-atrial re-entrant tachycardia in patients with congenital heart disease: factors associated with disease severity.

PMID: 29016882
Journal: EUROPACE
Year: 2018
Reference: Europace. 2018 Aug 1;20(8):1343-1351. doi: 10.1093/europace/eux180.
Impact factor:
Publication type: Paper in international publication
Authors: Casaldaliga Ferrer, Jaume; Dos Subira, Laura; Francisco Pascual, Jaume; Garcia-Dorado Garcia, David; Miranda, Berta; Moya Mitjans, Angel; Perez-Rodon, Jordi; Pijuan Domenech, Antonia; Rivas Gandara, Nuria; Roca-Luque, Ivo et al.
DOI: 10.1093/europace/eux180

Hippocampal and Deep Gray Matter Nuclei Atrophy Is Relevant for Explaining Cognitive Impairment in MS: A Multicenter Study.

PMID: 27686487
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2017
Reference: AJNR Am J Neuroradiol. 2017 Jan;38(1):18-24. doi: 10.3174/ajnr.A4952. Epub 2016 Sep 29.
Impact factor:
Publication type: Paper in international publication
Authors: Arevalo, M J; Bisecco, A; Damjanovic, D; De Stefano, N; Enzinger, C; Fazekas, F; Filippi, M; Gallo, A; Hulst, H E; Muhlert, N et al.
DOI: 10.3174/ajnr.A4952

Comparison between gadolinium-enhanced 2D T1-weighted gradient-echo and spin-echo sequences in the detection of active multiple sclerosis lesions on 3.0T MRI.

PMID: 27456965
Journal: EUROPEAN RADIOLOGY
Year: 2017
Reference: Eur Radiol. 2017 Apr;27(4):1361-1368. doi: 10.1007/s00330-016-4503-3. Epub 2016 Jul 25.
Impact factor:
Publication type: Paper in international publication
Authors: Alcaide-Leon, P; Auger, C; Aymerich, F X; Corral, J F; Huerga, E; Mitjana, R; Montalban, X; Pareto, D; Rovira, A; Sastre-Garriga, J et al.
DOI: 10.1007/s00330-016-4503-3

Effect of bioprostheses anti-calcification treatment: comparative follow-up between Mitroflow LX and Magna pericardial xenografts using a propensity score-weighted analysis.

PMID: 28040770
Journal: Interactive Cardiovascular and Thoracic Surgery
Year: 2017
Reference: Interact Cardiovasc Thorac Surg. 2017 Mar 1;24(3):335-341. doi: 10.1093/icvts/ivw378.
Impact factor:
Publication type: Paper in international publication
Authors: Blasco-Lucas, Arnau; Casos, Kelly; Galinanes, Manuel; Gracia-Baena, Juan Manuel; Perez, Maria-Llanos; Permanyer, Eduard; Rios, Remedios et al.
DOI: 10.1093/icvts/ivw378

Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis.

PMID: 28063616
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2017
Reference: J Neuroimmunol. 2017 Feb 15;303:62-65. doi: 10.1016/j.jneuroim.2016.12.006. Epub 2016 Dec 18.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Cermeno, Jose C; Comabella, Manuel; Malhotra, Sunny; Matute-Blanch, Clara; Midaglia, Luciana; Montalban, Xavier; Rio, Jordi; Vidal-Jordana, Angela; Villar, Luisa M et al.
DOI: 10.1016/j.jneuroim.2016.12.006

Highlights from the 31st ECTRIMS congress - Barcelona 2015.

PMID: 26684283
Journal: Multiple Sclerosis Journal
Year: 2016
Reference: Mult Scler. 2016 Jan;22(1):7-10. doi: 10.1177/1352458515620500.
Impact factor:
Publication type: Review in international publication
Authors: Sastre-Garriga, Jaume; Wiendl, Heinz et al.
DOI: 10.1177/1352458515620500

The first volume of MSJ-ETC.

PMID: 28607713
Journal: Multiple sclerosis journal - experimental, transla
Year: 2016
Reference: Mult Scler J Exp Transl Clin. 2016 Jan 22;2:2055217315626042. doi: 10.1177/2055217315626042. eCollection 2016 Jan-Dec.
Impact factor:
Publication type: Editorail in international publication
Authors: Cohen, Jeffrey A; Kim, Ho Jin; Tintore, Mar et al.
DOI: 10.1177/2055217315626042

HLA-DRB*1501 associations with magnetic resonance imaging measures of grey matter pathology in multiple sclerosis.

PMID: 27237756
Journal: Multiple Sclerosis and Related Disorders
Year: 2016
Reference: Mult Scler Relat Disord. 2016 May;7:47-52. doi: 10.1016/j.msard.2016.03.003. Epub 2016 Mar 7.
Impact factor:
Publication type: Paper in international publication
Authors: Chard, Declan T; Hardy, John; Houlden, Henry; Liu, Zheng; Miller, David H; Mok, Kin Y; Muhlert, Nils; Pardini, Matteo; Samson, Rebecca S; Sethi, Varun et al.
DOI: 10.1016/j.msard.2016.03.003

[A message from the new Editor of the Revista de Neurologia].

PMID: 27270673
Journal: REVISTA DE NEUROLOGIA
Year: 2016
Reference: Rev Neurol. 2016 Jun 16;62(12):529.
Impact factor:
Publication type: Editorial in national publication
Authors: Sastre-Garriga, J et al.
DOI:

Spanish consensus on the use of natalizumab (Tysabri(R))-2013.

PMID: 24360652
Journal: NEUROLOGIA
Year: 2015
Reference: Neurologia. 2015 Jun;30(5):302-14. doi: 10.1016/j.nrl.2013.10.004. Epub 2013 Dec 19.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Cermeno, J C; Arroyo, R; Fernandez, O; Garcia-Merino, J A; Hernandez, M A; Izquierdo, G; Meca, J; Montalban, X; Moral, E; Olascoaga, J et al.
DOI: 10.1016/j.nrl.2013.10.004

Multiple deep white matter lesions mimicking multiple sclerosis as an unusual complication of a left atrial myxoma.

PMID: 24852926
Journal: MULT SCLER J
Year: 2015
Reference: Mult Scler. 2015 Jan;21(1):111-2. doi: 10.1177/1352458514535678. Epub 2014 May 22.
Impact factor:
Publication type: Paper in international publication
Authors: Negrotto, Laura et al.
DOI: 10.1177/1352458514535678

A patient care program for adjusting the autoinjector needle depth according to subcutaneous tissue thickness in patients with multiple sclerosis receiving subcutaneous injections of glatiramer acetate.

PMID: 25225835
Journal: J NEUROSCI NURS
Year: 2015
Reference: J Neurosci Nurs. 2015 Feb;47(1):E22-30. doi: 10.1097/JNN.0000000000000086.
Impact factor:
Publication type: Paper in international publication
Authors: Carrasco, Maria Luisa Vergara; Carreno, Maria Rosario Coll; Castano, Adela Harto; Felices, Ana Maria Bernad; Gil, Maria Jesus Diaz; Hidalgo, Leonor Mariana Rubio; Martinez, Pablo Francoli; Masid, Maria Luisa Sanchez; Morales, Jaime Cordero; Ocana, Rosalia Horno et al.
DOI: 10.1097/JNN.0000000000000086

Antibodies to MOG and AQP4 in adults with neuromyelitis optica and suspected limited forms of the disease.

PMID: 25344373
Journal: MULT SCLER J
Year: 2015
Reference: Mult Scler. 2015 Jun;21(7):866-874. doi: 10.1177/1352458514555785. Epub 2014 Oct 24.
Impact factor:
Publication type: Paper in international publication
Authors: Armangue, Thais; Arrambide, Georgina; Benito-Leon, Julian; Blanco, Yolanda; Calvo, Alvaro Cobo; Casanova, Bonaventura; Dalmau, Josep; Graus, Francesc; Hoftberger, Romana; Olascoaga, Javier et al.
DOI: 10.1177/1352458514555785

Epstein-Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis.

PMID: 24622348
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Oct;20(11):1545. doi: 10.1177/1352458514527025. Epub 2014 Mar 12.
Impact factor:
Publication type: Letter or abstract
Authors: Fissolo, Nicolas et al.
DOI: 10.1177/1352458514527025

Thrombotic thrombocytopenic purpura-haemolytic uremic syndrome in relapsing-remitting multiple sclerosis patients on high-dose interferon beta.

PMID: 24696053
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Nov;20(13):1788-9. doi: 10.1177/1352458514529614. Epub 2014 Apr 2.
Impact factor:
Publication type: Letter or abstract
Authors: Arrambide, Georgina et al.
DOI: 10.1177/1352458514529614

Comment on: 'Prevalence of brain magnetic resonance imaging meeting Barkhof and McDonald criteria for dissemination in space among headache patients'

PMID: 24351437
Journal: Multiple Sclerosis Journal
Year: 2014
Reference: Mult Scler. 2014 Jun;20(7):897-8. doi: 10.1177/1352458513515959. Epub 2013 Dec 18.
Impact factor:
Publication type: Paper in international publication
Authors: Montalban, Xavier; Rovira, Alex; Tintore, Mar; Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458513515959

Long-term impact of interferon beta-1b in patients with CIS: 8-year follow-up of BENEFIT.

PMID: 24218527
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2014
Reference: J Neurol Neurosurg Psychiatry. 2014 Nov;85(11):1183-9. doi: 10.1136/jnnp-2013-306222. Epub 2013 Nov 11.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, F; Edan, G; Freedman, M S; Hartung, H-P; Herrmann, J; Kappos, L; Lanius, V; Miller, D; Montalban, X; Pleimes, D et al.
DOI: 10.1136/jnnp-2013-306222

In vivo imaging of brain aromatase in female baboons: [11C]vorozole kinetics and effect of the menstrual cycle.

PMID: 24447618
Journal: Molecular Imaging
Year: 2013
Reference: Mol Imaging. 2013 Nov-Dec;12(8). doi: 10.2310/7290.2013.00068.
Impact factor:
Publication type: Paper in international publication
Authors: Alexoff, David; Biegon, Anat; Carter, Pauline; Fowler, Joanna S; Kim, Sunny W; Logan, Jean; Muench, Lisa; Pareto, Deborah; Shea, Coreen; Xu, Youwen et al.
DOI: 10.2310/7290.2013.00068

Optimization of [(11)C]raclopride positron emission tomographic rat studies: comparison of methods for image quantification.

PMID: 23651503
Journal: Molecular Imaging
Year: 2013
Reference: Mol Imaging. 2013 Jun;12(4):257-62.
Impact factor:
Publication type: Paper in international publication
Authors: Abasolo, Ibane; Farre, Magi; Gispert, Juan Domingo; Llop, Jordi; Millan, Olga; Pareto, Deborah; Ruiz, Alba; Torrent, Elia et al.
DOI:

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.

PMID: 24278027
Journal: PLoS Genetics
Year: 2013
Reference: PLoS Genet. 2013 Nov;9(11):e1003926. doi: 10.1371/journal.pgen.1003926. Epub 2013 Nov 21.
Impact factor:
Publication type: Paper in international publication
Authors: Bahlo, Melanie; Barcellos, Lisa; Barcellos, Lisa F; Bernardinelli, Luisa; Booth, David; Booth, David R; Broadley, Simon; Brown, Matthew A; Butzkueven, Helmut; Carrington, Mary et al.
DOI: 10.1371/journal.pgen.1003926

Sex and gender issues in multiple sclerosis.

PMID: 23858327
Journal: Therapeutic advances in neurological disorders
Year: 2013
Reference: Ther Adv Neurol Disord. 2013 Jul;6(4):237-48. doi: 10.1177/1756285613488434.
Impact factor:
Publication type: Letter or abstract
Authors: Gold, Ralf; Harbo, Hanne F; Tintore, Mar et al.
DOI: 10.1177/1756285613488434

Whole-body vibration training for patients with neurodegenerative disease.

PMID: 22336858
Journal: Cochrane Database of Systematic Reviews
Year: 2012
Reference: Cochrane Database Syst Rev. 2012 Feb 15;(2):CD009097. doi: 10.1002/14651858.CD009097.pub2.
Impact factor:
Publication type: Review in national publication
Authors: Bonfill Cosp, Xavier; Fort Vanmeerhaeghe, Azahara; Rigau Comas, David; Romero-Rodriguez, Daniel; Roque i Figuls, Marta; Santoyo Medina, Carme; Sitja Rabert, Merce et al.
DOI: 10.1002/14651858.CD009097.pub2

Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects.

PMID: 22516081
Journal: LANCET NEUROLOGY
Year: 2012
Reference: Lancet Neurol. 2012 May;11(5):467-76. doi: 10.1016/S1474-4422(12)70059-5.
Impact factor:
Publication type: Review in national publication
Authors: Balcer, Laura J; Banwell, Brenda; Barkhof, Frederik; Calabresi, Peter; Clanet, Michel; Cohen, Jeffrey A; Cohen, Jeffrey A; Comi, Giancarlo; Cutter, Gary R; Freedman, Mark S et al.
DOI: 10.1016/S1474-4422(12)70059-5

Which walking capacity tests to use in multiple sclerosis? A multicentre study providing the basis for a core set.

PMID: 21952098
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 Mar;18(3):364-71. doi: 10.1177/1352458511420598. Epub 2011 Sep 27.
Impact factor:
Publication type: Clinical guide
Authors: Bethoux, Francois; Dalgas, Ulrik; de Groot, Vincent; de Noordhout, Benoit Maertens; Feys, Peter; Gebara, Benoit; Gijbels, Domien; Knuts, Kathy; Maamagi, Heigo; Medina, Carme Santoyo et al.
DOI: 10.1177/1352458511420598

Effect of time of day on walking capacity and self-reported fatigue in persons with multiple sclerosis: a multi-center trial.

PMID: 21969239
Journal: Multiple Sclerosis Journal
Year: 2012
Reference: Mult Scler. 2012 Mar;18(3):351-7. doi: 10.1177/1352458511419881. Epub 2011 Oct 3.
Impact factor:
Publication type: Paper in international publication
Authors: Bethoux, F; Dalgas, U; de Groot, V; de Noordhout, B Maertens; Feys, P; Gebara, B; Gijbels, D; Knuts, K; Romberg, A; Santoyo, C et al.
DOI: 10.1177/1352458511419881

[Natalizumab for relapsing-remitting multiple sclerosis.]

PMID: 21193250
Journal: NEUROLOGIA
Year: 2011
Reference: Neurologia. 2011 Jul-Aug;26(6):357-68. doi: 10.1016/j.nrl.2010.10.004. Epub 2010 Dec 28.
Impact factor:
Publication type: Review in national publication
Authors: ; et al.
DOI: 10.1016/j.nrl.2010.10.004

New insights in the pathophysiology and treatment of multiple sclerosis spasticity and related symptoms. Foreword.

PMID: 21449852
Journal: Expert review of neurotherapeutics
Year: 2011
Reference: Expert Rev Neurother. 2011 Apr;11(4 Suppl):1.
Impact factor:
Publication type: Editorail in international publication
Authors: Montalban, Xavier et al.
DOI: 10.1586/ern.11.24

MRI monitoring of immunomodulation in relapse-onset multiple sclerosis trials.

PMID: 22143362
Journal: Nature Reviews Neurology
Year: 2011
Reference: Nat Rev Neurol. 2011 Dec 6;8(1):13-21. doi: 10.1038/nrneurol.2011.190.
Impact factor:
Publication type: Review in international publication
Authors: Barkhof, Frederik; de Stefano, Nicola; Fazekas, Franz; Filippi, Massimo; Kappos, Ludwig; Li, David K; Miller, David H; Montalban, Xavier; O'Connor, Paul; Petkau, John et al.
DOI: 10.1038/nrneurol.2011.190

Decision tree based fuzzy classifier of H-1 magnetic resonance spectra from cerebrospinal fluid samples

PMID: 90000005
Journal: FUZZY SETS AND SYSTEMS
Year: 2011
Reference: Fuzzy Sets and Systems, 170,1, 1 May 2011, 43-63
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.fss.2011.01.003

Fenton-treated functionalized diamond nanoparticles as gene delivery system.

PMID: 20047335
Journal: ACS Nano
Year: 2010
Reference: ACS Nano. 2010 Jan 26;4(1):65-74. doi: 10.1021/nn901616c.
Impact factor:
Publication type: Paper in international publication
Authors: Alvaro, Mercedes; Garcia, Hermenegildo; Herance, Jose Raul; Martin, Roberto et al.
DOI: 10.1021/nn901616c

Development and pilot phase of a European MS register.

PMID: 20443020
Journal: JOURNAL OF NEUROLOGY
Year: 2010
Reference: J Neurol. 2010 Oct;257(10):1620-7. Epub 2010 May 5.
Impact factor:
Publication type: Paper in international publication
Authors: Bergmann, Sverrir; Flachenecker, Peter; Khil, Laura; Kowalewski, Mariusz; Pascu, Ion; Perez-Miralles, Francisco; Sastre-Garriga, Jaume; Zwingers, Thomas et al.
DOI: 10.1007/s00415-010-5578-4

Oral laquinimod in patients with relapsing-remitting multiple sclerosis: 36-week double-blind active extension of the multi-centre, randomized, double-blind, parallel-group placebo-controlled study.

PMID: 20834039
Journal: MULTIPLE SCLEROSIS
Year: 2010
Reference: Mult Scler. 2010 Nov;16(11):1360-6. Epub 2010 Sep 8.
Impact factor:
Publication type: Paper in international publication
Authors: Abramsky, O; Abramsky, O; Antiguedad, A R; Arbizu, T; Arbizu, T; Arbizu, T; Arroyo, R; Barcena, J; Bartos, L; Bertolotto, A et al.
DOI: 10.1177/1352458510378127

Multiple sclerosis: Lesion location may predict disability in multiple sclerosis.

PMID: 21131911
Journal: Nature Reviews Neurology
Year: 2010
Reference: Nat Rev Neurol. 2010 Dec;6(12):648-9.
Impact factor:
Publication type: Editorail in international publication
Authors: Sastre-Garriga, Jaume; Tintore, Mar et al.
DOI: 10.1038/nrneurol.2010.161

Can rate of brain atrophy in multiple sclerosis be explained by clinical and MRI characteristics?

PMID: 19091881
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Apr;15(4):465-71. Epub 2008 Dec 17.
Impact factor:
Publication type: Paper in international publication
Authors: Barkhof, F; Barkhof, F; Comi, G; de Stefano, N; Fazekas, F; Filippi, M; Filippi, M; Fredricksen, J; Kappos, L; Knol, D L et al.
DOI: 10.1177/1352458508100505

MRI as an outcome in multiple sclerosis clinical trials.

PMID: 19949043
Journal: NEUROLOGY
Year: 2009
Reference: Neurology. 2009 Dec 1;73(22):1932; author reply 1932-3.
Impact factor:
Publication type: Letter or abstract
Authors: Barkhof, F; Daumer, Martin; De Stefano, Nicola; Ebers, George; Fazekas, F; Filippi, Massimo; Frederiksen, J; Kappos, L; Miller, D H; Montalban, X et al.
DOI: 10.1212/WNL.0b013e3181bd6b8f

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score.

PMID: 19879194
Journal: LANCET NEUROLOGY
Year: 2009
Reference: Lancet Neurol. 2009 Dec;8(12):1111-9.
Impact factor:
Publication type: Paper in international publication
Authors: Arnason, B G W; Ascherio, Alberto; Aubin, Cristin; Bauer, David; Chibnik, Lori B; Comi, G; Cook, S; Cui, Jing; De Jager, Philip L; Ebers, G C et al.
DOI: 10.1016/S1474-4422(09)70275-3

Early treatment: PreCISe-ly what the patient needs.

PMID: 20106344
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2009
Reference: J Neurol Sci. 2009 Dec;287S1:S2-S6.
Impact factor:
Publication type: Paper in international publication
Authors: et al.
DOI: 10.1016/S0022-510X(09)71293-6

[Epileptic status due to non-ketotic hyperglycemia].

PMID: 15766515
Journal: MEDICINA CLINICA
Year: 2005
Reference: Med Clin (Barc). 2005 Mar 19;124(10):398-9. doi: 10.1157/13072580.
Impact factor:
Publication type: Letter or abstract
Authors: Purroy, Francesc; Rio, Jordi; Rovira, Alex; Toledo, Manuel et al.
DOI: 10.1157/13072580

[Epileptic status due to non-ketotic hyperglycemia].

PMID: 15766515
Journal: MEDICINA CLINICA
Year: 2005
Reference: Med Clin (Barc). 2005 Mar 19;124(10):398-9. doi: 10.1157/13072580.
Impact factor: 1.005
Publication type: Letter or abstract
Authors: Rovira, Alex, Rio, Jordi, Purroy, Francesc, Toledo, Manuel et al.
DOI: 10.1157/13072580

Thesis

Immunosenescence in multiple sclerosis: innate immunity as a possible therapeutic target

PhD student: Maria Arantza Dema Etxezarreta
Director/s: Herena Eixarch Ahufinger, Carmen Espejo Ruiz
University: Universitat Autònoma de Barcelona
Year: 2023

Clinical monitoring of multiple sclerosis patients using digital technology

PhD student: Luciana Midaglia Fernandez
Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga
University:
Year: 2023

Esclerosis Múltiple y COVID-19: Factores de riesgo e inmunidad humoral y celular

PhD student: Ana Zabalza de Torres, Ana Zabalza de Torres
Director/s: Mar Tintore Subirana, Georgina Arrambide García
University: Universidad Autònoma de Barcelona
Year: 2022

Los astrocitos como diana en la prevención de la neurodegeneración en pacientes con esclerosis múltiple

PhD student: Clara Matute Blanch
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín
University:
Year: 2021

Inmunomodulación de la vía Th17 como estrategia terapéutica para la esclerosis múltiple

PhD student: Julia Enric Rubio Roca
Director/s: Miguel Chillon Rodriguez, Xavier Montalban Gairín
University:
Year: 2020

The gut microbiota as a therapeutic target in multiple sclerosis

PhD student: Laura Calvo Barreiro
Director/s: Carmen Espejo Ruiz, Herena Eixarch Ahufinger, Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2020

Búsqueda de variantes genéticas causales y estudio de sus implicaciones funcionales en pacientes con esclerosis múltiple

PhD student: Elia Gil Varea
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín, Sunny Malhotra Sareen
University: Universidad Autònoma de Barcelona
Year: 2018

Factores pronósticos no radiológicos de conversión a esclerosis múltiple y discapacidad de los síndromes clínicamente aislados.

PhD student: Raúl Pelayo Vergara
Director/s: Xavier Montalban Gairín
University:
Year: 2016

Estudio de pseudoatrofia cerebral en los pacientes con esclerosis múltiple

PhD student: Angela Vidal Jordana
Director/s: Xavier Montalban Gairín, Jaume Sastre Garriga
University: Universidad Autònoma de Barcelona
Year: 2016

Indicadores precoces de respuesta al tratamiento con interferón en pacientes con esclerosis múltiple

PhD student: Joaquin Castillo Justribo
Director/s: Xavier Montalban Gairín, Jordi Rio Izquierdo
University: Universidad Autònoma de Barcelona
Year: 2016

Brain Volume and Brain Metabolite Changes in the First Stages of Primary Progressive Multiple Sclerosis - A short-term longitudinal study

PhD student: Jaume Sastre Garriga
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2015

Búsqueda de biomarcadores asociados con la respuesta al interferón-beta en pacientes con esclerosis múltiple.

PhD student: Sunny Malhotra Sareen
Director/s: Manuel Comabella Lopez, Xavier Montalban Gairín
University:
Year: 2014

Estudio clínico y de resonancia magnética del rendimiento cognitivo en síndromes neurológicos aislados sugestivos de esclerosis múltiple

PhD student: M Jesus Arevalo Navines
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2014

Búsqueda de Biomarcadores Asociados con la Respuesta al Tratamiento con Interferón-beta en Pacientes con Esclerosis Múltiple Remitente-Recurrente.

PhD student: Manuel Comabella Lopez
Director/s: Xavier Montalban Gairín
University: Universidad Autònoma de Barcelona
Year: 2013

Estudio clínico y de resonancia magnética orientado al conocimiento del sustrato patológico de la discapacidad en la esclerosis múltiple primariamente progresiva

PhD student: Carmen Tur Gomez, Carmen Tur Gomez
Director/s: Xavier Montalban Gairín, Vicenç Fonollosa Pla
University: Universidad Autònoma de Barcelona
Year: 2012

Funció de les metalotioneínes en la patogenia de l’encefalomielitis autoimmune experimental i de l’esclerosi múltiple. Implicacions terapèutiques

PhD student: Carmen Espejo Ruiz
Director/s:
University: Universidad Autònoma de Barcelona
Year: 2005

Blog

News

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

Rates

Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

More information