Skip to main content

Growth and Development

Our group is dedicated to paediatric research. We are interested in rare respiratory and endocrinological diseases, and also in common paediatric problems such as normal growth, asthma, neonatal pathology and imaging diagnosis, as well as minority diseases. Our goal is to transfer the findings of clinical and genetic studies to the widespread clinical practice and the general population, with the long-term objective of obtaining better diagnoses, implementing better therapeutic practices and improving the health of children.

Our group is part of CIBERER (Biomedical Research Networking Centre on Rare Diseases) (CIBERER U712) and European Reference Networks (ERN) for rare diseases ERN LUNG and Endo-ERN.

Team

Sarah Elizabeth Villarroel Bravo

Sarah Elizabeth Villarroel Bravo

Research technician
Growth and Development
Read more
Jose Miguel Escudero Fernandez

Jose Miguel Escudero Fernandez

Predoctoral researcher
Growth and Development
Read more
Alba García Moral

Alba García Moral

Predoctoral researcher
Growth and Development
Read more
Ana Creus Molins

Ana Creus Molins

Predoctoral researcher
Growth and Development
Read more
Andrea Puga Iñiguez

Andrea Puga Iñiguez

Research technician
Growth and Development
Read more
Castillo Martínez, María

Castillo Martínez, María

Predoctoral researcher
Growth and Development
Read more
Sarah Elizabeth Villarroel Bravo

Sarah Elizabeth Villarroel Bravo

Research technician
Growth and Development
Read more
Jose Miguel Escudero Fernandez

Jose Miguel Escudero Fernandez

Predoctoral researcher
Growth and Development
Read more
Alba García Moral

Alba García Moral

Predoctoral researcher
Growth and Development
Read more
Ana Creus Molins

Ana Creus Molins

Predoctoral researcher
Growth and Development
Read more
Andrea Puga Iñiguez

Andrea Puga Iñiguez

Research technician
Growth and Development
Read more
Castillo Martínez, María

Castillo Martínez, María

Predoctoral researcher
Growth and Development
Read more

Research lines

Preterm respiratory diseases and the influence of nutrition.

Bronchopulmonary dysplasia. Our current line in this subject is centered in studying the role of imaging in predicting the outcome of preterm babies with this chronic respiratory disease.

Omega-3 fatty acids supplementation and oxidative stress in preterm infants. The goal of this study is whether omega-3 fatty acids supplementation can decrease the incidence and severity of bronchopulmonary dysplasia and preterm retinopathy.

IP: Félix Castillo Salinas

Asthma and recurrent wheezing. Infant and children lung function.

Asthma and recurrent wheezing: Inflammatory markers. Insight into its pathogenesis and treatment.

Infant and children lung function: Reference values and clinical application.

IP: Antonio Moreno Galdó, Inés de Mir Messa

Cystic fibrosis.

Our paediatric Cystic Fibrosis Unit is one of the most important in Spain regarding number of patients and clinical research. We are the only centre in Spain collaborating in the European Cystic Fibrosis Clinical Trial Network, and in the Cystic Fibrosis Core Network of ERN-Lung. Besides clinical investigation, we are working in translational lab projects in collaboration with the Genetic Medicine group to study  the role of the eicosanoid pathway in the lung inflammation of this patients and, more importantly, to personalise the treatments for cystic fibrosis patients through the implementation of primary cultures of epithelial cells (bronchial, nasal) and organoids (rectal epithelium) and the study of transcripts and genomics by next generation sequencing in clinically diagnosed CF patients but with incomplete genomic characterization.

IP: Silvia Gartner Tizzano

Rare respiratory diseases: Primary ciliary dyskinesia, Paediatric interstitial lung diseases and paediatric pulmonary hypertension.

1.1 Primary ciliary dyskinesia (PCD): We are a referral centre for diagnosis of PCD and we have established a clinical and research collaboration network with other national and international PCD diagnostic centres. 

1.2 Paediatric interstitial lung diseases. We are leading the Spanish ISCIII registry for paediatric interstitial lung diseases and have started a project to characterize the incidence and the molecular basis of these rare diseases in Spain. We have international collaborations in this field (chILD EU registry and an E-rare 3 funded clinical trial).

1.3 Paediatric pulmonary hypertension. We have an active collaboration with the Spanish Registry of Paediatric Pulmonary Hypertension (REHIPED) and are developing an intense epidemiologic research in this area.


IP: Antonio Moreno Galdó

Blog

News

The study, in which Vall d'Hebron participates, helps to understand the variability among patients with retinitis pigmentosa.

Es va reconèixer la tasca de més de 70 professionals dedicades a aquesta malaltia pulmonar, tant assistencial com de recerca.

The two studies awarded has been the research for a the ciliary dyskinesia diagnosis led by the VHIR’s Growth and Development Group and the EPISCAN II, in which Dr. Miravitlles has participated.