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Growth and Development

Our group is dedicated to paediatric research. We are interested in rare respiratory and endocrinological diseases, and also in common paediatric problems such as normal growth, asthma, neonatal pathology and imaging diagnosis, as well as minority diseases. Our goal is to transfer the findings of clinical and genetic studies to the widespread clinical practice and the general population, with the long-term objective of obtaining better diagnoses, implementing better therapeutic practices and improving the health of children.

Our group is part of CIBERER (Biomedical Research Networking Centre on Rare Diseases) (CIBERER U712) and European Reference Networks (ERN) for rare diseases ERN LUNG and Endo-ERN.

Publications

Analysis of perceived risk and satisfaction with telematic follow-up in patients and families of congenital diaphragmatic hernia patients during SARS-CoV-2 pandemia.

PMID: 35835633
Journal: Journal of healthcare quality research
Year: 2022
Reference: J Healthc Qual Res. 2022 Jun 23. pii: S2603-6479(22)00054-9. doi: 10.1016/j.jhqr.2022.05.009.
Impact factor: 0
Publication type: Paper in international publication
Authors: de Mir, I, Khan, H A, Lopez Fernandez, S, Oliver, B, Rocha, O, Guillen, G, Molino, J A, Iglesias, I, Lopez, M et al.
DOI: 10.1016/j.jhqr.2022.05.009

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study.

PMID: 35816621
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2022
Reference: Am J Respir Crit Care Med. 2022 Jul 11. doi: 10.1164/rccm.202202-0392OC.
Impact factor: 21.405
Publication type: Paper in international publication
Authors: Mall, Marcus A, Brugha, Rossa, Gartner, Silvia, Legg, Julian, Mondejar-Lopez, Pedro, Prais, Dario, Ratjen, Felix, Davies, Jane C, Wainwright, Claire E, Wu, Pan et al.
DOI: 10.1164/rccm.202202-0392OC

Intralymphatic GAD-alum (Diamyd(R)) improves glycaemic control in Type 1 diabetes with HLA DR3-DQ2.

PMID: 35665810
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2022
Reference: J Clin Endocrinol Metab. 2022 Jun 6. pii: 6602344. doi: 10.1210/clinem/dgac343.
Impact factor: 5.958
Publication type: Paper in international publication
Authors: Ludvigsson, Johnny, Nowak, Christoph, Lind, Marcus, Sumnik, Zdenek, Pelikanova, Terezie, Chavez, Lia Nattero, Lundberg, Elena, Rica, Itxaso, Martinez-Brocca, Maria A, Ruiz de Adana, Mari Sol et al.
DOI: 10.1210/clinem/dgac343

Clinical practice guidelines for transsexual, transgender and gender diverse minors.

PMID: 35534418
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Apr;96(4):349.e1-349.e11. doi: 10.1016/j.anpede.2022.02.002. Epub 2022 May 6.
Impact factor: 1.5
Publication type: Paper in international publication
Authors: Guerrero-Fernandez, Julio, Gomez Balaguer, Marcelino, Rica Echevarria, Itxaso, Campos-Martorell, Ariadna, Chueca-Guindulain, Maria Jesus, Garcia Garcia, Emilio, Hoyos-Gurrea, Raul, Lopez de Lara, Diego, Lopez-Siguero, Juan Pedro, Martos Tello, Jose Maria et al.
DOI: 10.1016/j.anpede.2022.02.002

Updated guidance on the management of children with cystic fibrosis transmembrane conductance regulator-related metabolic syndrome/cystic fibrosis screen positive, inconclusive diagnosis (CRMS/CFSPID).

PMID: 33257262
Journal: Journal of Cystic Fibrosis
Year: 2021
Reference: J Cyst Fibros. 2021 Sep;20(5):810-819. doi: 10.1016/j.jcf.2020.11.006. Epub 2020 Nov 27.
Impact factor: 5.482
Publication type: Paper in international publication
Authors: Barben, Jurg, Castellani, Carlo, Munck, Anne, Davies, Jane C, deWinter, Karin, Gartner, Silvia, Kashirskaya, Nataliya, Mayell, Sarah J, Linnane, Barry, McColley, Susanna et al.
DOI: 10.1016/j.jcf.2020.11.006

Myocardial Geometry and Dysfunction in Morbidly Obese Adolescents (BMI 35-40 kg/m(2)).

PMID: 34392890
Journal: AMERICAN JOURNAL OF CARDIOLOGY
Year: 2021
Reference: Am J Cardiol. 2021 Oct 15;157:128-134. doi: 10.1016/j.amjcard.2021.07.026. Epub 2021 Aug 13.
Impact factor: 2.778
Publication type: Paper in international publication
Authors: Ventura, Paula S, Yeste, Diego, Riaza-Martin, Lucia, Arciniegas, Larry, Clemente, Maria, Torres, Marisa, Amigo, Nuria, Giralt, Gemma, Roses-Noguer, Ferran, Sabate-Rotes, Anna et al.
DOI: 10.1016/j.amjcard.2021.07.026

Nasal High-Flow for Weaning Preterm Newborns with Risk of Chronic Lung Disease from nCPAP.

PMID: 34396498
Journal: AMERICAN JOURNAL OF PERINATOLOGY
Year: 2021
Reference: Am J Perinatol. 2021 Jul 16. doi: 10.1055/s-0041-1732422.
Impact factor: 1.862
Publication type: Paper in international publication
Authors: Gregoraci Fernandez, Angela, Comunas Gomez, Juan Jose, Rodriguez-Losada, Olalla, Flores Espana, Vanessa, Gros Turpin, Anna, Perez Hoyos, Santiago, Castillo Salinas, Felix et al.
DOI: 10.1055/s-0041-1732422

Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis.

PMID: 34330959
Journal: Scientific Reports
Year: 2021
Reference: Sci Rep. 2021 Jul 30;11(1):15511. doi: 10.1038/s41598-021-94798-x.
Impact factor: 4.38
Publication type: Paper in international publication
Authors: Calucho, Maite, Gartner, Silvia, Barranco, Paula, Fernandez-Alvarez, Paula, Perez, Raquel Garcia, Tizzano, Eduardo F et al.
DOI: 10.1038/s41598-021-94798-x

Unusual context of CENPJ variants and primary microcephaly: compound heterozygosity and nonconsanguinity in an Argentinian patient.

PMID: 32549991
Journal: Human genome variation
Year: 2020
Reference: Hum Genome Var. 2020 Jun 8;7:20. doi: 10.1038/s41439-020-0105-3. eCollection 2020.
Impact factor: 0
Publication type: Paper in international publication
Authors: Cueto-Gonzalez, Anna M, Fernandez-Cancio, Monica, Fernandez-Alvarez, Paula, Garcia-Arumi, Elena, Tizzano, Eduardo F et al.
DOI: 10.1038/s41439-020-0105-3

Reactions on re-exposure following negative and inconclusive follow-up food challenges in children with acute FPIES.

PMID: 32534148
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2020
Reference: J Allergy Clin Immunol Pract. 2020 Oct;8(9):3228-3231.e3. doi: 10.1016/j.jaip.2020.05.040. Epub 2020 Jun 10.
Impact factor: 7.574
Publication type: Paper in international publication
Authors: Machinena, A, Pascal, M, Echeverria, L, Barni, S, Garriga-Baraut, T, Arasi, S, Moure, J D, Gomez-Carballa, A, Martinon-Torres, F, Boyle, R J et al.
DOI: 10.1016/j.jaip.2020.05.040

[Diagnostic accuracy of the tri-ponderal mass index in identifying the unhealthy metabolic obese phenotype in obese patients].

PMID: 32446672
Journal: ANALES DE PEDIATRIA
Year: 2020
Reference: An Pediatr (Barc). 2020 May 20. pii: S1695-4033(20)30149-1. doi: 10.1016/j.anpedi.2020.04.004.
Impact factor: 1.313
Publication type: Paper in national publication
Authors: Yeste, Diego, Clemente, Maria, Campos, Ariadna, Fabregas, Anna, Mogas, Eduard, Soler, Laura, Carrascosa, Antonio et al.
DOI: 10.1016/j.anpedi.2020.04.004

Diagnostic criteria for acute FPIES: what are we missing?

PMID: 31821916
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2020
Reference: J Allergy Clin Immunol Pract. 2020 May;8(5):1717-1720.e2. doi: 10.1016/j.jaip.2019.11.034. Epub 2019 Dec 9.
Impact factor: 7.574
Publication type: Paper in international publication
Authors: Vazquez-Ortiz, Marta, Argiz, Laura, Machinena, Adrianna, Echeverria, Luis, Blasco, Cristina, Prieto, Ana, Infante, Sonsoles, Vila, Leticia, Garcia, Emilio, Gonzalez-Delgado, Purificacion et al.
DOI: 10.1016/j.jaip.2019.11.034

Prospective assessment of diagnostic tests for pediatric penicillin allergy, from clinical history to challenge tests(,,).

PMID: 29803713
Journal: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
Year: 2018
Reference: Ann Allergy Asthma Immunol. 2018 Aug;121(2):235-244.e3. doi: 10.1016/j.anai.2018.05.013. Epub 2018 May 25.
Impact factor: 3.263
Publication type: Paper in international publication
Authors: Ibanez, Maria Dolores, Audicana, Maria Teresa, Del Rio, Pablo Rodriguez, Lasa, Eva Maria, Joral, Alejandro, Ruiz-Hornillos, Javier, Munoz, Candelaria, Traseira, Carmen Gomez, Escudero, Carmelo, Olaguibel Rivera, Jose Maria et al.
DOI: 10.1016/j.anai.2018.05.013

Clinical and immunological profile of children aged 5-9 years with persistent egg allergy before oral immunotherapy with egg. A multicenter, randomized controlled trial of the Spanish Society of Pediatric Allergy, Asthma and Clinical Immunology (SEICAP).

PMID: 29804794
Journal: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Year: 2018
Reference: Allergol Immunopathol (Madr). 2018 Sep - Oct;46(5):415-420. doi: 10.1016/j.aller.2018.01.004. Epub 2018 May 24.
Impact factor: 1.644
Publication type: Paper in international publication
Authors: Martorell, A, Echeverria, L, Martin-Munoz, M F, Martorell, C, Belver, M T, Alonso Lebrero, E, Zapatero, L, Fuentes, V, Pique, M, Plaza, A et al.
DOI: 10.1016/j.aller.2018.01.004

Detection of Bacteriophage Particles Containing Antibiotic Resistance Genes in the Sputum of Cystic Fibrosis Patients.

PMID: 29765367
Journal: Frontiers in Microbiology
Year: 2018
Reference: Front Microbiol. 2018 May 1;9:856. doi: 10.3389/fmicb.2018.00856. eCollection 2018.
Impact factor: 4.019
Publication type: Paper in international publication
Authors: Brown-Jaque, Maryury, Rodriguez Oyarzun, Lirain, Cornejo-Sanchez, Thais, Martin-Gomez, Maria T, Gartner, Silvia, de Gracia, Javier, Rovira, Sandra, Alvarez, Antonio, Jofre, Joan, Gonzalez-Lopez, Juan J et al.
DOI: 10.3389/fmicb.2018.00856

Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.

PMID: 29710837
Journal: Pharmaceuticals (Basel, Switzerland)
Year: 2018
Reference: Pharmaceuticals (Basel). 2018 Apr 29;11(2). pii: ph11020037. doi: 10.3390/ph11020037.
Impact factor: 0
Publication type: Paper in international publication
Authors: Fernandez-Cancio, Monica, Camats, Nuria, Fluck, Christa E, Zalewski, Adam, Dick, Bernhard, Frey, Brigitte M, Monne, Raquel, Toran, Nuria, Audi, Laura, Pandey, Amit V et al.
DOI: 10.3390/ph11020037

Oral immunotherapy for food allergy: A Spanish guideline. Immunotherapy egg and milk Spanish guide (items guide). Part I: Cow milk and egg oral immunotherapy: Introduction, methodology, rationale, current state, indications contraindications and oral immunotherapy build-up phase.

PMID: 28662773
Journal: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Year: 2017
Reference: Allergol Immunopathol (Madr). 2017 Jul - Aug;45(4):393-404. doi: 10.1016/j.aller.2017.05.001. Epub 2017 Jun 26.
Impact factor: 1.439
Publication type: Clinical guide
Authors: Martorell, A, Alonso, E, Echeverria, L, Escudero, C, Garcia-Rodriguez, R, Blasco, C, Bone, J, Borja-Segade, J, Bracamonte, T, Claver, A et al.
DOI: 10.1016/j.aller.2017.05.001

Oral immunotherapy for food allergy: A Spanish guideline. Egg and milk immunotherapy Spanish guide (ITEMS GUIDE). Part 2: Maintenance phase of cow milk (CM) and egg oral immunotherapy (OIT), special treatment dosing schedules. Models of dosing schedules of OIT with CM and EGG.

PMID: 28676231
Journal: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Year: 2017
Reference: Allergol Immunopathol (Madr). 2017 Sep - Oct;45(5):508-518. doi: 10.1016/j.aller.2017.05.002. Epub 2017 Jul 1.
Impact factor: 1.439
Publication type: Clinical guide
Authors: Martorell, A, Alonso, E, Echeverria, L, Escudero, C, Garcia-Rodriguez, R, Blasco, C, Bone, J, Borja-Segade, J, Bracamonte, T, Claver, A et al.
DOI: 10.1016/j.aller.2017.05.002

Whole-brain structural connectivity in dyskinetic cerebral palsy and its association with motor and cognitive function.

PMID: 28608616
Journal: HUMAN BRAIN MAPPING
Year: 2017
Reference: Hum Brain Mapp. 2017 Sep;38(9):4594-4612. doi: 10.1002/hbm.23686. Epub 2017 Jun 13.
Impact factor: 4.53
Publication type: Paper in international publication
Authors: Pueyo, Roser, van den Heuvel, Martijn P, Toro, Esther, Ballester-Plane, Julia, Schmidt, Ruben, Laporta-Hoyos, Olga, Junque, Carme, Vazquez, Elida, Delgado, Ignacio, Zubiaurre-Elorza, Leire et al.
DOI: 10.1002/hbm.23686

Oral immunotherapy for food allergy: a spanish guideline - Part 2. Immunotherapy Egg and Milk Spanish Guide (items guide).

PMID: 28593864
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2017
Reference: J Investig Allergol Clin Immunol. 2017;27(5):279-290. doi: 10.18176/jiaci.0178. Epub 2017 Jun 8.
Impact factor: 3.094
Publication type: Clinical guide
Authors: Claver, A, Corzo, J L, De la Hoz, B, Del Olmo, R, Dominguez, O, Fuentes-Aparicio, V, Guallar, I, Larramona, H, Martin-Munoz, F, Matheu, V et al.
DOI: 10.18176/jiaci.0178

Blog

News

The study, in which Vall d'Hebron participates, helps to understand the variability among patients with retinitis pigmentosa.

Es va reconèixer la tasca de més de 70 professionals dedicades a aquesta malaltia pulmonar, tant assistencial com de recerca.

The two studies awarded has been the research for a the ciliary dyskinesia diagnosis led by the VHIR’s Growth and Development Group and the EPISCAN II, in which Dr. Miravitlles has participated.