About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 37014530 Journal: PEDIATRIC NEPHROLOGY Year: 2023 Reference: Pediatr Nephrol. 2023 Sep;38(9):3035-3042. doi: 10.1007/s00467-023-05913-1. Epub 2023 Apr 4. Impact factor: Publication type: Paper in international publication Authors: Adams, B; Aksenova, M; Alpay, H; Andersen, R; Ariceta, G; Ariceta, G; Aris, A M; Atmis, B; Baudouin, V; Bayrakci, U S et al. DOI: 10.1007/s00467-023-05913-1
PMID: 37487638 Journal: Life Science Alliance Year: 2023 Reference: Life Sci Alliance. 2023 Jul 24;6(10):e202201886. doi: 10.26508/lsa.202201886. Print 2023 Oct. Impact factor: Publication type: Paper in international publication Authors: Barbas, Coral; Chaix, Amandine; Herrero, J Ignacio; Lamas, Santiago; Lin, Terry; Meseguer, Anna; Miguel, Veronica; Panda, Satchidananda; Ramos, Ricardo; Rey-Serra, Carlos et al. DOI: 10.26508/lsa.202201886
PMID: 37644568 Journal: Orphanet Journal of Rare Diseases Year: 2023 Reference: Orphanet J Rare Dis. 2023 Aug 29;18(1):245. doi: 10.1186/s13023-023-02856-6. Impact factor: Publication type: Paper in international publication Authors: Arango-Sancho, Pedro; Barreda-Bonis, Ana Coral; Bou-Torrent, Rosa; Broseta-Monzo, Jose Jesus; Casado, Enrique; Chocron-de-Benzaquen, Sara; Chocron-de-Benzaquen, Sara; Gomez-Alonso, Carlos; Olmedilla-Ishishi, Yoko; Pintos-Morell, Guillem et al. DOI: 10.1186/s13023-023-02856-6
PMID: 37689688 Journal: World Journal of Emergency Surgery Year: 2023 Reference: World J Emerg Surg. 2023 Sep 9;18(1):45. doi: 10.1186/s13017-023-00513-8. Impact factor: Publication type: Review in international publication Authors: Abu-Zidan, Fikri M; Agnoletti, Vanni; Aisoni, Filippo; Ammendola, Michele; Ansaloni, Luca; Bala, Miklosh; Biffl, Walter; Catena, Fausto; Ceccarelli, Graziano; Ceresoli, Marco et al. DOI: 10.1186/s13017-023-00513-8
PMID: 34971403 Journal: PEDIATRIC NEPHROLOGY Year: 2022 Reference: Pediatr Nephrol. 2022 Aug;37(8):1867-1875. doi: 10.1007/s00467-021-05226-1. Epub 2021 Dec 31. Impact factor: Publication type: Paper in international publication Authors: Abranches, M; Akman, S; Alpay, H; Ariceta, G; Atmis, B; Bael, A; Bakkaloglu, S A; Bakkaloglu, Sevcan A; Bayrakci, U S; Bhimma, R et al. DOI: 10.1007/s00467-021-05226-1
PMID: 33779754 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Jun 23;37(7):1270-1280. doi: 10.1093/ndt/gfab075. Impact factor: Publication type: Paper in international publication Authors: Allende, Natalia; Ariceta, Gema; Avila, Ana; Barros, Xoana; Bravo, Luis; Cabello, Virginia; Cano-Megias, Marta; Caravaca-Fontan, Fernando; Cruz, Sonia; Da Silva, Iara et al. DOI: 10.1093/ndt/gfab075
PMID: 35681685 Journal: Cancers Year: 2022 Reference: Cancers (Basel). 2022 May 30;14(11). pii: cancers14112702. doi: 10.3390/cancers14112702. Impact factor: Publication type: Paper in international publication Authors: Campistol, Miriam; Celma, Ana; de Torres, Ines; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Santamaria, Anna; Semidey, Maria E; Trilla, Enrique et al. DOI: 10.3390/cancers14112702
PMID: 35643375 Journal: KIDNEY INTERNATIONAL Year: 2022 Reference: Kidney Int. 2022 Sep;102(3):604-612. doi: 10.1016/j.kint.2022.04.029. Epub 2022 May 25. Impact factor: Publication type: Paper in international publication Authors: Anarat, Ali; Ariceta, Gema; Aurelle, Manon; Baiko, Sergey; Balasz-Chmielewska, Irena; Benetti, Elisa; Benz, Marcus R; Bjerre, Anna; Boyer, Olivia; Clave, Stephanie et al. DOI: 10.1016/j.kint.2022.04.029
PMID: 34140257 Journal: Actas Urologicas Espanolas Year: 2021 Reference: Actas Urol Esp (Engl Ed). 2021 Jul-Aug;45(6):447-454. doi: 10.1016/j.acuroe.2020.09.008. Epub 2021 Jun 16. Impact factor: Publication type: Paper in national publication Authors: Celma, A; de Torres, I M; Morote, J; Planas, J; Regis, L; Roche, S; Schwartzmann, I; Semidey, M E et al. DOI: 10.1016/j.acuroe.2020.09.008
PMID: 34090639 Journal: ANALES DE PEDIATRIA Year: 2021 Reference: An Pediatr. 2021 Jun;94(6):415-417. doi: 10.1016/j.anpede.2020.05.008. Epub 2021 Apr 27. Impact factor: Publication type: Letter whit IF Authors: Adam Lancet, Victor; Ariceta Iraola, Gema; Garcia Jimenez, Maria Concepcion; Justa Roldan, Maria Luisa; Romero Salas, Yolanda et al. DOI: 10.1016/j.anpedi.2020.05.019
PMID: 34078418 Journal: Orphanet Journal of Rare Diseases Year: 2021 Reference: Orphanet J Rare Dis. 2021 Jun 2;16(1):251. doi: 10.1186/s13023-021-01872-8. Impact factor: Publication type: Paper in international publication Authors: Andersone, Ilze; Ariceta, Gema; Awan, Atif; Bacchetta, Justine; Bassanese, Giulia; Bockenhauer, Detlef; Buescher, Anja; Capasso, Giovambattista; Cornelissen, Elisabeth; Decramer, Stephane et al. DOI: 10.1186/s13023-021-01872-8
PMID: 34069888 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 May 18;10(10). pii: jcm10102174. doi: 10.3390/jcm10102174. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Gabaldon, Maria-Alejandra; Jacobs-Cacha, Conxita; Lopez-Hellin, Joan; Moreso, Francesc; Puig-Gay, Natalia; Sellares, Joana; Seron, Daniel; Soler, Maria Jose; Vergara, Ander et al. DOI: 10.3390/jcm10102174
PMID: 32699617 Journal: Clinical Kidney Journal Year: 2020 Reference: Clin Kidney J. 2019 Sep 26;13(3):371-379. doi: 10.1093/ckj/sfz107. eCollection 2020 Jun. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Buffin-Meyer, Benedicte; Conte-Auriol, Francoise; Decramer, Stephane; Feitz, Wout; Fossum, Magdalena; Hindryckx, An; Klein, Julie; Levtchenko, Elena; Lounis, Nadia et al. DOI: 10.1093/ckj/sfz107
PMID: 32605590 Journal: Orphanet Journal of Rare Diseases Year: 2020 Reference: Orphanet J Rare Dis. 2020 Jun 30;15(1):172. doi: 10.1186/s13023-020-01434-4. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Beck-Nielsen, Signe; Boot, Annemieke; Brandi, Maria Luisa; Jandhyala, Ravi; Levtchenko, Elena; Makitie, Outi; Mughal, Zulf; Nilsson, Ola; Padidela, Raja et al. DOI: 10.1186/s13023-020-01434-4
PMID: 31506748 Journal: WORLD JOURNAL OF UROLOGY Year: 2020 Reference: World J Urol. 2020 Jun;38(6):1481-1491. doi: 10.1007/s00345-019-02946-w. Epub 2019 Sep 10. Impact factor: Publication type: Paper in international publication Authors: Borque-Fernando, Angel; Celma, Ana; de Torres, Ines; Esteban, Luis Mariano; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Semidey, Maria Eugenia; Trilla, Enrique et al. DOI: 10.1007/s00345-019-02946-w
PMID: 32418146 Journal: PEDIATRIC NEPHROLOGY Year: 2020 Reference: Pediatr Nephrol. 2020 Sep;35(9):1669-1678. doi: 10.1007/s00467-020-04584-6. Epub 2020 May 17. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Aufricht, Christoph; Edefonti, Alberto; Eibensteiner, Fabian; Jankauskiene, Augustina; Klaus, Günter; Paglialonga, Fabio; Ranchin, Bruno; Ritschl, Valentin; Schmitt, Claus Peter et al. DOI: 10.1007/s00467-020-04584-6
PMID: 31038179 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2019 Reference: Nephrol Dial Transplant. 2019 Nov 1;34(11):1932-1940. doi: 10.1093/ndt/gfz069. Impact factor: Publication type: Paper in international publication Authors: Baiko, Sergey; Bakkaloglu, Sevcan A; Bayazit, Aysun K; Boehm, Michael; Bonthuis, Marjolein; Cvetkovic, Mirjana; Edvardsson, Vidar O; Fomina, Svitlana; Groothoff, Jaap W; Harambat, Jerome et al. DOI: 10.1093/ndt/gfz069
PMID: 31005637 Journal: Journal of Pediatric Urology Year: 2019 Reference: J Pediatr Urol. 2019 May;15(3):213-220. doi: 10.1016/j.jpurol.2019.03.015. Epub 2019 Mar 28. Impact factor: Publication type: Review in international publication Authors: Ariceta, G; Asensio, M; Gander, R; Lara, L E; Lopez, M; Lopez, M; Molino, J A; Royo, G F et al. DOI: 10.1016/j.jpurol.2019.03.015
PMID: 31010601 Journal: AMERICAN JOURNAL OF KIDNEY DISEASES Year: 2019 Reference: Am J Kidney Dis. 2019 Aug;74(2):193-202. doi: 10.1053/j.ajkd.2019.02.014. Epub 2019 Apr 19. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Aysun, Karabay Bayazit; Bilge, Ilmay; Borzych-Duzalka, Dagmara; Fila, Marc; Holtta, Tuula; Kang, Hee Gyung; Paglialonga, Fabio; Ranchin, Bruno; Schaefer, Franz et al. DOI: 10.1053/j.ajkd.2019.02.014
PMID: 30899871 Journal: Kidney international reports Year: 2019 Reference: Kidney Int Rep. 2018 Dec 3;4(3):434-446. doi: 10.1016/j.ekir.2018.11.010. eCollection 2019 Mar. Impact factor: Publication type: Paper in international publication Authors: Ardissino, Gianluigi; Ariceta, Gema; Blasco, Miquel; Cohen, David J; Cresseri, Donata; Fakhouri, Fadi; Fremeaux-Bacchi, Veronique; Gasteyger, Christoph; Generolova, Galina; Greenbaum, Larry et al. DOI: 10.1016/j.ekir.2018.11.010
PMID: 29753540 Journal: JOURNAL OF PEDIATRICS Year: 2018 Reference: J Pediatr. 2018 Aug;199:22-28.e6. doi: 10.1016/j.jpeds.2018.03.052. Epub 2018 May 9. Impact factor: Publication type: Paper in international publication Authors: Afonso, Alberto Caldas; Akinci, Nurver; Alpay, Harika; Anarat, Ali; Antoniewicz, Jolanta; Ariceta, Gema; Azukaitis, Karolis; Balasz-Chmielewska, Irena; Bald, Martin; Bayazit, Aysun Karabay et al. DOI: 10.1016/j.jpeds.2018.03.052
PMID: 28610805 Journal: NEFROLOGIA Year: 2018 Reference: Nefrologia. 2018 May - Jun;38(3):333-335. doi: 10.1016/j.nefro.2017.03.019. Epub 2017 Jun 10. Impact factor: Publication type: Letter or abstract Authors: Balcells, Joan; Del Toro, Mireia; Martinez de Companon, Zurine; Moreno, Antonio; Poblet-Puig, Miriam; Valles, Griselda; Vilalta, Ramon et al. DOI: 10.1016/j.nefro.2017.03.019
PMID: 29674338 Journal: Clinical Journal of the American Society of Nephrology Year: 2018 Reference: Clin J Am Soc Nephrol. 2018 Jun 7;13(6):874-883. doi: 10.2215/CJN.11401017. Epub 2018 Apr 19. Impact factor: Publication type: Paper in international publication Authors: Afonso, Alberto Caldas; Agbas, Ayse; Ariceta, Gema; De Rechter, Stephanie; Deschenes, Georges; Devuyst, Olivier; Duzova, Ali; Emma, Francesco; Giordano, Ugo; Godefroid, Nathalie et al. DOI: 10.2215/CJN.11401017
PMID: 29636297 Journal: Journal of Pediatric Urology Year: 2018 Reference: J Pediatr Urol. 2018 Oct;14(5):442.e1-442.e8. doi: 10.1016/j.jpurol.2018.03.009. Epub 2018 Mar 31. Impact factor: Publication type: Paper in international publication Authors: Ariceta, G; Asensio, M; Gander, R; Lopez, M; Molino, J A; Munoz, M; Royo, G F et al. DOI: 10.1016/j.jpurol.2018.03.009
PMID: 28471339 Journal: Journal of Child Sexual Abuse Year: 2017 Reference: J Child Sex Abus. 2017 Apr;26(3):246-269. doi: 10.1080/10538712.2017.1288186. Impact factor: Publication type: Paper in international publication Authors: Avecilla-Palau, Angels; Cobo, Jesus; Faro, Concepcio; Fernandez, Maria-Isabel; Lopetegui, Lourdes; Lopez, Silvia; Martinez, Cristina; Monteagudo, Monica; Pujol-Ribera, Enriqueta et al. DOI: 10.1080/10538712.2017.1288186
PMID: 28648215 Journal: NEFROLOGIA Year: 2017 Reference: Nefrologia. 2017 May-Jun;37(3):355. doi: 10.1016/j.nefro.2017.05.003. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Bermejo, Sheila; Burballa, Carla; Crespo, Marta; Gimeno, Javier; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores; Sanchez-Guerri, Ignacio et al. DOI: 10.1016/j.nefro.2017.05.003
PMID: 26571219 Journal: PEDIATRIC RESEARCH Year: 2016 Reference: Pediatr Res. 2016 Mar;79(3):496-501. doi: 10.1038/pr.2015.243. Epub 2015 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Arango, Ana; Blanco, Fiona; Cantos, Virginia; Chocron, Sara; Coto, Eliecer; Gil-Pena, Helena; Gomez, Juan; Gonzalez, Luz E; Hernandez, Olaya; Madrid, Alvaro et al. DOI: 10.1038/pr.2015.243
PMID: 26974972 Journal: PLoS One Year: 2016 Reference: PLoS One. 2016 Mar 14;11(3):e0151339. doi: 10.1371/journal.pone.0151339. eCollection 2016. Impact factor: Publication type: Paper in international publication Authors: Altadill, Tatiana; Byers, Stephen; Campoy, Irene; Cheema, Amrita K; Colas, Eva; Gil-Moreno, Antonio; Gill, Kirandeep; Lanau, Lucia; Reventos, Jaume; Rigau, Marina et al. DOI: 10.1371/journal.pone.0151339
PMID: 26422688 Journal: Gaceta Sanitaria Year: 2016 Reference: Gac Sanit. 2016 Jan-Feb;30(1):55-8. doi: 10.1016/j.gaceta.2015.08.006. Epub 2015 Oct 1. Impact factor: Publication type: Paper in international publication Authors: Anton, Laura; Fernandez, Esteve; Fu, Marcela; Martinez, Cristina; Martinez-Sanchez, Jose M; Quiros, Nuria; Riccobene, Anna; Salto, Esteve et al. DOI: 10.1016/j.gaceta.2015.08.006
PMID: 27595515 Journal: NEFROLOGIA Year: 2016 Reference: Nefrologia. 2016 Nov-Dec;36(6):660-666. doi: 10.1016/j.nefro.2016.05.018. Epub 2016 Aug 30. Impact factor: Publication type: Paper in international publication Authors: Arias-Cabrales, Carlos; Bermejo, Sheila; Burballa, Carla; Crespo, Marta; Gimeno, Javier; Mir, Marisa; Pascual, Julio; Perez-Saez, Maria Jose; Redondo-Pachon, Dolores; Sanchez-Guerri, Ignacio et al. DOI: 10.1016/j.nefro.2016.05.018
PMID: 25209656 Journal: GUT Year: 2015 Reference: Gut. 2015 Sep;64(9):1379-88. doi: 10.1136/gutjnl-2013-306236. Epub 2014 Sep 10. Impact factor: Publication type: Paper in international publication Authors: Alonso, Carmen; Azpiroz, Fernando; de Torres, Ines; Fortea, Marina; Gonzalez-Castro, Ana M; Guilarte, Mar; Lobo, Beatriz; Martinez, Cristina; Mosquera, Jose L; Pigrau, Marc et al. DOI: 10.1136/gutjnl-2013-306236
PMID: 26239461 Journal: Journal of Clinical Medicine Year: 2015 Reference: J Clin Med. 2015 May 18;4(5):998-1009. doi: 10.3390/jcm4050998. Impact factor: Publication type: Review in international publication Authors: Agraz, Irene; Espinel, Eugenia; Fort, Joan; Ibernon, Meritxell; Ramos, Natalia; Seron, Daniel et al. DOI: 10.3390/jcm4050998
PMID: 25886171 Journal: BMC NEPHROL Year: 2015 Reference: BMC Nephrol. 2015 Feb 18;16:22. doi: 10.1186/s12882-015-0002-z. Impact factor: Publication type: Paper in international publication Authors: Anarat, A; Ardissino, G; Ariceta, Gema; Baskin, E; Beck, B; Benz, K; Benzing, T; Bergmann, Carsten; Beringer, O; Bernhardt, W et al. DOI: 10.1186/s12882-015-0002-z
PMID: 25348508 Journal: NEPHROL DIAL TRANSPL Year: 2015 Reference: Nephrol Dial Transplant. 2015 Mar;30(3):475-80. doi: 10.1093/ndt/gfu329. Epub 2014 Oct 26. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Bedoya, Rafael; Bravo, Juan; Bueno, Alberto; Camacho, Juan A; Cantarell, Carmen; Crespo, Jose; Daza, Antonio; Garcia-Nieto, Victor; Gil Calvo, Marta et al. DOI: 10.1093/ndt/gfu329
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
