About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 37885338 Journal: KAOHSIUNG JOURNAL OF MEDICAL SCIENCES Year: 2023 Reference: Kaohsiung J Med Sci. 2023 Oct 27. doi: 10.1002/kjm2.12771. Impact factor: Publication type: Paper in international publication Authors: Abe, Hiroshi; Ahn, Sang Bong; Algaba, Ferran; An, Jihyun; Arai, Taeang; Atsukawa, Masanori; Buti, Maria; Cheung, Ka Shing; Cho, Yong Kyun; Chuang, Wan-Long et al. DOI: 10.1002/kjm2.12771
PMID: 37951467 Journal: Cirugia espanola Year: 2023 Reference: Cir Esp (Engl Ed). 2023 Nov 9:S2173-5077(23)00194-1. doi: 10.1016/j.cireng.2023.02.013. Impact factor: Publication type: Paper in international publication Authors: Areny, A; Arevalo, J; Campoy, I; Cantero-Recasens, G; Duran, M; Hernandez Granados, Pilar; Lopez-Cano, Manuel; Martinez, C; Meseguer, A; Nemours, S et al. DOI: 10.1016/j.cireng.2023.02.013
PMID: 35485759 Journal: Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Year: 2022 Reference: Cir Pediatr. 2022 Apr 1;35(2):94-98. doi: 10.54847/cp.2022.02.19. Impact factor: 0 Publication type: Letter or abstract Authors: Gander, R, Asensio, M, Royo, G F, Lopez, M, Coma, A, Munoz, M, Cruz, A, Rios, H, Ariceta, G, Molino, J A et al. DOI: 10.54847/cp.2022.02.19
PMID: 35484379 Journal: Scientific Reports Year: 2022 Reference: Sci Rep. 2022 Apr 28;12(1):6926. doi: 10.1038/s41598-022-10352-3. Impact factor: 4.38 Publication type: Paper in international publication Authors: Castro, Luis, Nemours, Stephane, Aranda, Miguel, Ferrer, Marina, Sanchez, Alex, Morote, Joan, Cantero-Recasens, Gerard, Meseguer, Anna, Semidey, Maria E, Ribatallada-Soriano, Didac et al. DOI: 10.1038/s41598-022-10352-3
PMID: 33532864 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2022 Reference: Nephrol Dial Transplant. 2022 Mar 25;37(4):687-696. doi: 10.1093/ndt/gfab019. Impact factor: 5.992 Publication type: Paper in international publication Authors: Domingo-Gallego, Andrea, Pybus, Marc, Bullich, Gemma, Furlano, Monica, Ejarque-Vila, Laia, Lorente-Grandoso, Laura, Ruiz, Patricia, Fraga, Gloria, Lopez Gonzalez, Mercedes, Pinero-Fernandez, Juan Alberto et al. DOI: 10.1093/ndt/gfab019
PMID: 35211308 Journal: Clinical Kidney Journal Year: 2022 Reference: Clin Kidney J. 2021 Nov 15;15(3):545-552. doi: 10.1093/ckj/sfab215. eCollection 2022 Mar. Impact factor: 4.452 Publication type: Paper in international publication Authors: Roca, Neus, Jatem, Elias, Abo, Anabel, Santacana, Maria, Cruz, Alejandro, Madrid, Alvaro, Fraga, Gloria, Martin, Marisa, Gonzalez, Jorge, Martinez, Cristina et al. DOI: 10.1093/ckj/sfab215
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
