About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are
We are experts on the following areas:
To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.
PMID: 37702442 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2023 Reference: N Engl J Med. 2023 Sep 14;389(11):987-997. doi: 10.1056/NEJMoa2300161. Epub 2023 Sep 12. Impact factor: Publication type: Paper in international publication Authors: Alberici, Irene; Alberici, Irene; Alpay, Harika; Anarat, Ali; Ariceta, Gema; Ariceta, Gema; Ariceta, Gema; Atmis, Bahriye; Barbi, Egidio; Baskin, Esra et al. DOI: 10.1056/NEJMoa2300161
PMID: 37752558 Journal: Orphanet Journal of Rare Diseases Year: 2023 Reference: Orphanet J Rare Dis. 2023 Sep 27;18(1):304. doi: 10.1186/s13023-023-02882-4. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Ariceta, Gema; Beck-Nielsen, Signe Sparre; Boot, Annemieke M; Brandi, Maria Luisa; Briot, Karine; de Lucas Collantes, Carmen; Emma, Francesco; Giannini, Sandro; Haffner, Dieter et al. DOI: 10.1186/s13023-023-02882-4
PMID: 37799531 Journal: Frontiers in Psychology Year: 2023 Reference: Front Psychol. 2023 Sep 18;14:1209245. doi: 10.3389/fpsyg.2023.1209245. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Canizares, Silvia; Ciudin, Andreea; Ciudin, Andreea; Comas, Marta; Comas, Marta; Cuatrecasas, Guillem; Diaz-Trastoy, Olaia; Flores, Lilliam; Goni, Fernando; Gutierrez-Medina, Sonsoles et al. DOI: 10.3389/fpsyg.2023.1209245
PMID: 37257423 Journal: DERMATOLOGY Year: 2023 Reference: Dermatology. 2023;239(5):685-693. doi: 10.1159/000530813. Epub 2023 May 31. Impact factor: Publication type: Paper in international publication Authors: Aguayo-Ortiz, Rafael; Ariceta, Gema; Bassas-Freixas, Patricia; Bernia-Petit, Eduardo; Bonfill-Orti, Montserrat; Canueto, Javier; Comas, Jordi; Cruz, Alejandro; Deza, Gustavo; Florez-Menendez, Angeles et al. DOI: 10.1159/000530813
PMID: 35625978 Journal: Cancers Year: 2022 Reference: Cancers (Basel). 2022 May 11;14(10). pii: cancers14102374. doi: 10.3390/cancers14102374. Impact factor: Publication type: Paper in international publication Authors: Abascal, Jose M; Borque-Fernando, Angel; Celma, Anna; de Torres, Ines M; Esteban, Luis M; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Santamaria, Anna et al. DOI: 10.3390/cancers14102374
PMID: 34375498 Journal: BJU INTERNATIONAL Year: 2022 Reference: BJU Int. 2022 May;129(5):627-633. doi: 10.1111/bju.15568. Epub 2021 Aug 25. Impact factor: Publication type: Paper in international publication Authors: Celma, Anna; de Torres, Ines M; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Roche, Sarai; Santamaria, Anna; Schwartzmann, Ivan; Semidey, Maria E et al. DOI: 10.1111/bju.15568
PMID: 35513740 Journal: Molecular and cellular pediatrics Year: 2022 Reference: Mol Cell Pediatr. 2022 May 5;9(1):9. doi: 10.1186/s40348-022-00141-3. Impact factor: Publication type: Review in international publication Authors: Arbeiter, Klaus; Ariceta, Gema; Bartosova, Maria; Bayazit, Aysun K; Buscher, Rainer; Caliskan, Salim; Cerkauskiene, Rimante; Drozdz, Dorota; Fathallah-Shaykh, Sahar; Klaus, Gunter et al. DOI: 10.1186/s40348-022-00141-3
PMID: 35485759 Journal: Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Year: 2022 Reference: Cir Pediatr. 2022 Apr 1;35(2):94-98. doi: 10.54847/cp.2022.02.19. Impact factor: Publication type: Letter or abstract Authors: Ariceta, G; Asensio, M; Coma, A; Cruz, A; Gander, R; Lopez, M; Molino, J A; Munoz, M; Rios, H; Royo, G F et al. DOI: 10.54847/cp.2022.02.19
PMID: 33988730 Journal: PEDIATRIC NEPHROLOGY Year: 2021 Reference: Pediatr Nephrol. 2021 Nov;36(11):3733-3740. doi: 10.1007/s00467-021-05089-6. Epub 2021 May 14. Impact factor: Publication type: Paper in international publication Authors: Brambilla, Marta; Caporale, Olga; Consolo, Silvia; Grassi, Maria Rosa; Gual, Alejandro Cruz; Montini, Giovanni; Paglialonga, Fabio et al. DOI: 10.1007/s00467-021-05089-6
PMID: 33987651 Journal: HUMAN MOLECULAR GENETICS Year: 2021 Reference: Hum Mol Genet. 2021 Jul 9;30(15):1413-1428. doi: 10.1093/hmg/ddab131. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Burballa, Carla; Butnaru, Cristian M; Cantero-Recasens, Gerard; Duran, Monica; Malhotra, Vivek; Meseguer, Anna; Sarro, Eduard et al. DOI: 10.1093/hmg/ddab131
PMID: 33929692 Journal: JOURNAL OF NEPHROLOGY Year: 2021 Reference: J Nephrol. 2021 Dec;34(6):2053-2062. doi: 10.1007/s40620-021-01054-6. Epub 2021 Apr 30. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Burballa, Carla; Claverie-Martin, Felix; Meseguer, Anna; Vall-Palomar, Monica et al. DOI: 10.1007/s40620-021-01054-6
PMID: 33914889 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2021 Reference: Nephrol Dial Transplant. 2021 Aug 27;36(9):1585-1596. doi: 10.1093/ndt/gfab171. Impact factor: Publication type: Letter or abstract Authors: Ariceta, Gema; Bockenhauer, Detlef; Boyer, Olivia; Camilla, Roberta; Emma, Francesco; Ferraro, Pietro Manuel; Haffner, Dieter; Konrad, Martin; Levtchenko, Elena; Lopez-Garcia, Sergio Camilo et al. DOI: 10.1093/ndt/gfab171
PMID: 32299680 Journal: KIDNEY INTERNATIONAL Year: 2020 Reference: Kidney Int. 2020 Jun;97(6):1287-1296. doi: 10.1016/j.kint.2020.01.035. Epub 2020 Mar 6. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Barbour, Tom; Cataland, Spero; Haller, Hermann; Heyne, Nils; Kavanagh, David; Miyakawa, Yoshitaka; Ortiz, Stephan; Rondeau, Eric; Scully, Marie et al. DOI: 10.1016/j.kint.2020.01.035
PMID: 32282893 Journal: BRAIN Year: 2020 Reference: Brain. 2020 May 1;143(5):1414-1430. doi: 10.1093/brain/awaa084. Impact factor: Publication type: Paper in international publication Authors: Amman, Lukas; Calvo-Barreiro, Laura; Castillo, Joaquin; Clemente, Diego; Comabella, Manuel; Costa, Carme; Eixarch, Herena; Espejo, Carmen; Fissolo, Nicolas; Keller, Christian W et al. DOI: 10.1093/brain/awaa084
PMID: 32247519 Journal: Actas Urologicas Espanolas Year: 2020 Reference: Actas Urol Esp. 2020 May;44(4):245-250. doi: 10.1016/j.acuro.2019.11.006. Epub 2020 Apr 1. Impact factor: Publication type: Paper in national publication Authors: Arevalo, J; de Torres, I; Lorente, D; Meseguer, A; Morote, J; Salcedo, M T; Trilla, E et al. DOI: 10.1016/j.acuro.2019.11.006
PMID: 32162654 Journal: Journal of Molecular Cell Biology Year: 2020 Reference: J Mol Cell Biol. 2020 Jul 1;12(7):499-514. doi: 10.1093/jmcb/mjaa005. Impact factor: Publication type: Paper in international publication Authors: Batlle, Daniel; Bou-Teen, Diana; Bram, Richard J; Croatt, Anthony J; Duran, Monica; Fernandez-Majada, Vanesa; Gundelach, Justin H; Meseguer, Anna; Nath, Karl A; Rico, Ana et al. DOI: 10.1093/jmcb/mjaa005
PMID: 30958186 Journal: Journal of the Royal Society Interface Year: 2019 Reference: J R Soc Interface. 2019 Feb 28;16(151):20180709. doi: 10.1098/rsif.2018.0709. Impact factor: Publication type: Paper in international publication Authors: Alarcon, Tomas; Arevalo, Jazmine; Balocco, Simone; Bobadilla, Ana Victoria Ponce; Byrne, Helen M; Carraro, Thomas; Maini, Philip K; Meseguer, Anna; Sarro, Eduard et al. DOI: 10.1098/rsif.2018.0709
PMID: 30466966 Journal: Actas Urologicas Espanolas Year: 2019 Reference: Actas Urol Esp. 2019 Apr;43(3):118-123. doi: 10.1016/j.acuro.2018.08.003. Epub 2018 Nov 19. Impact factor: Publication type: Review in national publication Authors: Arevalo, J; Celma, A; Lorente, D; Meseguer, A; Morote, J; Nemours, S; Placer, J; Planas, J; Regis, L; Salvador, C et al. DOI: 10.1016/j.acuro.2018.08.003
PMID: 30922918 Journal: CANCER LETTERS Year: 2019 Reference: Cancer Lett. 2019 Jun 28;452:158-167. doi: 10.1016/j.canlet.2019.03.019. Epub 2019 Mar 25. Impact factor: Publication type: Paper in international publication Authors: Canovas, Veronica; Ciudad, Carlos J; de Torres, Ines; Felix, Alex J; Gomez, Valenti; Maggio, Valentina; Morote, Juan; Noe, Veronique; Paciucci, Rosanna; Semidey, Maria Eugenia et al. DOI: 10.1016/j.canlet.2019.03.019
PMID: 30808384 Journal: Orphanet Journal of Rare Diseases Year: 2019 Reference: Orphanet J Rare Dis. 2019 Feb 26;14(1):58. doi: 10.1186/s13023-019-1014-8. Impact factor: Publication type: Review in international publication Authors: Ariceta, Gema; Beck-Nielsen, Signe Sparre; de Lucas Collantes, Carmen; Haffner, Dieter; Jandhyala, Ravi; Levtchenko, Elena; Makitie, Outi; Mughal, Zulf; Nilsson, Ola; Schnabel, Dirk et al. DOI: 10.1186/s13023-019-1014-8
PMID: 29588143 Journal: Journal of Pediatric Urology Year: 2018 Reference: J Pediatr Urol. 2018 Jun;14(3):222-230. doi: 10.1016/j.jpurol.2018.01.027. Epub 2018 Mar 20. Impact factor: Publication type: Review in national publication Authors: Ariceta, Gema; Asensio, Marino; Gander, Romy; Garcia, Laura; Lopez, Manuel; Madrid, Alvaro; Molino, Jose Andres; Royo, Gloria Fatou et al. DOI: 10.1016/j.jpurol.2018.01.027
PMID: 29232664 Journal: NEPHRON Year: 2018 Reference: Nephron. 2018;138(4):280-286. doi: 10.1159/000485398. Epub 2017 Dec 12. Impact factor: Publication type: Paper in international publication Authors: Ariceta, Gema; Askiti, Varvara; Aufricht, Christoph; Bakkaloglu, Sevcan A; Canpolat, Nur; Dufek, Stephanie; Edefonti, Alberto; Ekim, Mesiha; Fischbach, Michel; Holtta, Tuula et al. DOI: 10.1159/000485398
PMID: 29464030 Journal: Oncotarget Year: 2018 Reference: Oncotarget. 2017 Dec 19;9(5):5736-5751. doi: 10.18632/oncotarget.23422. eCollection 2018 Jan 19. Impact factor: Publication type: Paper in international publication Authors: Alcaraz, Estefania; Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Meseguer, Anna; Morote, Juan; Pinna, Lorenzo A; Plana, Maria; Ramon Y Cajal, Santiago; Ruzzene, Maria et al. DOI: 10.18632/oncotarget.23422
PMID: 29146701 Journal: Clinical Journal of the American Society of Nephrology Year: 2018 Reference: Clin J Am Soc Nephrol. 2018 Feb 7;13(2):258-264. doi: 10.2215/CJN.02530317. Epub 2017 Nov 16. Impact factor: Publication type: Paper in international publication Authors: Agraz, Irene; Ariceta, Gema; Arredondo, Karla V; Carnicer, Clara; Jaramillo, Juliana; Jatem, Elias; Lara, Luis Enrique; Madrid, Alvaro; Martinez, Cristina; Ostos, Elena et al. DOI: 10.2215/CJN.02530317
PMID: 27663779 Journal: BMC HEALTH SERVICES RESEARCH Year: 2016 Reference: BMC Health Serv Res. 2016 Sep 23;16(1):517. doi: 10.1186/s12913-016-1764-0. Impact factor: Publication type: Paper in international publication Authors: Ballbe, Montse; Fernandez, Esteve; Fu, Marcela; Martinez, Cristina; Vilardell, Miquel et al. DOI: 10.1186/s12913-016-1764-0
PMID: 26440456 Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY Year: 2016 Reference: Int J Cardiol. 2016 Jan 1;202:485-7. doi: 10.1016/j.ijcard.2015.09.048. Epub 2015 Sep 25. Impact factor: 4.036 Publication type: Paper in international publication Authors: Baneras, Jordi, Buera, Irene, Oristrell, Gerard, Sansano, Irene, Fort, Joan, Ibernon, Meritxell, Marti, Gerard, Barrabes, Jose A, Dorado, David Garcia et al. DOI: 10.1016/j.ijcard.2015.09.048
PMID: 26538615 Journal: NEPHROLOGY DIALYSIS TRANSPLANTATION Year: 2016 Reference: Nephrol Dial Transplant. 2016 Mar;31(3):495-505. doi: 10.1093/ndt/gfv368. Epub 2015 Nov 3. Impact factor: 4.085 Publication type: Paper in international publication Authors: Ruiz, Juan C, Porrini, Esteban L, Diaz, Jose M, Moreso, Francisco, Delgado Mallen, Patricia I, Silva Torres, Irene, Ibernon, Meritxell, Bayes-Genis, Beatriz, Benitez-Ruiz, Rocio, Lampreabe, Ildefonso et al. DOI: 10.1093/ndt/gfv368
PMID: 26239461 Journal: Journal of Clinical Medicine Year: 2015 Reference: J Clin Med. 2015 May 18;4(5):998-1009. doi: 10.3390/jcm4050998. Impact factor: 0 Publication type: Review in international publication Authors: Seron, Daniel, Ramos, Natalia, Espinel, Eugenia, Agraz, Irene, Ibernon, Meritxell, Fort, Joan et al. DOI: 10.3390/jcm4050998
The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.
"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.
Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.
